GB1190546A - Process for producing L-Threonine and L-Valine - Google Patents
Process for producing L-Threonine and L-ValineInfo
- Publication number
- GB1190546A GB1190546A GB876869A GB876869A GB1190546A GB 1190546 A GB1190546 A GB 1190546A GB 876869 A GB876869 A GB 876869A GB 876869 A GB876869 A GB 876869A GB 1190546 A GB1190546 A GB 1190546A
- Authority
- GB
- United Kingdom
- Prior art keywords
- growth
- hydrocarbon
- thiamine
- atcc
- valine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
1,190,546. L-Threonine and L-valine by fermentation. KYOWA HAKKO KOGYO CO. Ltd. 18 Feb., 1969 [9 March, 1968], No. 8768/69. Heading C2C. L-Threonine and L-valine are produced by culturing a hydrocarbon-utilizing micro-organism, which requires thiamine and also isoleucine, α-ketobutyric acid, or α-aminobutyric acid for growth, under aerobic conditions in an aqueous nutrient medium containing thiamine, the growth requisite and a hydrocarbon or a mixture of hydrocarbons as the main source of carbon. Specified micro-organisms are Arthrobacter paraffineus ATCC 21220, Corynebacterium hydrocarboclastus ATCC 21221, and Brevibacterium ketoglutamicum ATCC 21222, and the hydrocarbon source is preferably one or more straight or branched chain alkanes of from 10 to 20 carbon atoms, e.g. a C 11 -C 18 nparaffin mixture or kerosene. The growth requisites are preferably present in an amount of 5-50 mg./l. medium, the concentration of thiamine is between 1 and 5 mg./l, and the pH is approximately 7. The medium may also contain citric, succinic, malic, fumaric or acetic acids, their sodium salts or L-homoserine, resulting in higher yields. Small amounts of other amino acids occur as by-products of the process. Specifications 1,117,154 and 1,122,508 are referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1494068A JPS5146836B1 (en) | 1968-03-09 | 1968-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1190546A true GB1190546A (en) | 1970-05-06 |
Family
ID=11874941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB876869A Expired GB1190546A (en) | 1968-03-09 | 1969-02-18 | Process for producing L-Threonine and L-Valine |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5146836B1 (en) |
| DE (1) | DE1912799A1 (en) |
| FR (1) | FR2003584A1 (en) |
| GB (1) | GB1190546A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2411209A1 (en) * | 1973-03-09 | 1974-09-12 | Ajinomoto Kk | METHOD FOR FERMENTATIONAL PRODUCTION OF L-VALIN |
| GB2147579A (en) * | 1983-08-05 | 1985-05-15 | Grace W R & Co | Production of L-amino acids from alpha-keto acids by fermentation |
| GB2147580A (en) * | 1983-08-05 | 1985-05-15 | Grace W R & Co | Improved process for producing L-amino acids from alpha-keto acids by fed-batch fermentation |
-
1968
- 1968-03-09 JP JP1494068A patent/JPS5146836B1/ja active Pending
-
1969
- 1969-02-18 GB GB876869A patent/GB1190546A/en not_active Expired
- 1969-03-07 DE DE19691912799 patent/DE1912799A1/en active Pending
- 1969-03-07 FR FR6906535A patent/FR2003584A1/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2411209A1 (en) * | 1973-03-09 | 1974-09-12 | Ajinomoto Kk | METHOD FOR FERMENTATIONAL PRODUCTION OF L-VALIN |
| GB2147579A (en) * | 1983-08-05 | 1985-05-15 | Grace W R & Co | Production of L-amino acids from alpha-keto acids by fermentation |
| GB2147580A (en) * | 1983-08-05 | 1985-05-15 | Grace W R & Co | Improved process for producing L-amino acids from alpha-keto acids by fed-batch fermentation |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1912799A1 (en) | 1970-09-24 |
| JPS5146836B1 (en) | 1976-12-11 |
| FR2003584A1 (en) | 1969-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |