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GB1094332A - A process for the production of ribonucleoside-5'-phosphate - Google Patents

A process for the production of ribonucleoside-5'-phosphate

Info

Publication number
GB1094332A
GB1094332A GB847665A GB847665A GB1094332A GB 1094332 A GB1094332 A GB 1094332A GB 847665 A GB847665 A GB 847665A GB 847665 A GB847665 A GB 847665A GB 1094332 A GB1094332 A GB 1094332A
Authority
GB
United Kingdom
Prior art keywords
ribonucleoside
chlorides
organic solvent
water
acid anhydride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB847665A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of GB1094332A publication Critical patent/GB1094332A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/02—Phosphorylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)

Abstract

Ribonucleoside - 51 - phosphates or salts thereof are prepared by reacting the corresponding ribonucleoside with metaboric acid or a salt thereof, in an organic solvent, to form the borate complex, phosphorylating, and contacting the resulting phosphorylated product with water which may contain alkali and may be mixed with an organic solvent. Specified phosphorylating agents are diphenyl- and dibenzylphosphoryl chlorides, O - benzylphosphorous-O,O - diphenylphosphoric acid anhydride, tetra - p - nitrophenylpyrophosphoric acid anhydride, pyrophosphoryl chlorides, and a mixture of POCl3 and water.
GB847665A 1964-02-26 1965-02-26 A process for the production of ribonucleoside-5'-phosphate Expired GB1094332A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1054264 1964-02-26

Publications (1)

Publication Number Publication Date
GB1094332A true GB1094332A (en) 1967-12-06

Family

ID=11753132

Family Applications (1)

Application Number Title Priority Date Filing Date
GB847665A Expired GB1094332A (en) 1964-02-26 1965-02-26 A process for the production of ribonucleoside-5'-phosphate

Country Status (4)

Country Link
CH (1) CH448103A (en)
DE (1) DE1620494A1 (en)
FR (1) FR1428186A (en)
GB (1) GB1094332A (en)

Also Published As

Publication number Publication date
CH448103A (en) 1967-12-15
DE1620494A1 (en) 1970-01-02
FR1428186A (en) 1966-02-11

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