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GB1084864A - Medicated lozenges - Google Patents

Medicated lozenges

Info

Publication number
GB1084864A
GB1084864A GB431665A GB431665A GB1084864A GB 1084864 A GB1084864 A GB 1084864A GB 431665 A GB431665 A GB 431665A GB 431665 A GB431665 A GB 431665A GB 1084864 A GB1084864 A GB 1084864A
Authority
GB
United Kingdom
Prior art keywords
lozenges
polyethylene glycol
medicament
candy base
tannate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB431665A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1084864A publication Critical patent/GB1084864A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A medicated lozenge comprises a hard candy base consisting essentially of sucrose and glucose having dispersed therein from 2-16% by wt. of a mixture of a medicament and a polyethylene glycol having an average M.W. in the range 4,000-20,000. The lozenges may be prepared by first preparing a molten candy base consisting essentially of sucrose and glucose, separately heating a mixture of the powdered medicament and an appropriate polyethylene glycol until a uniform dispersion or solution of the medicament in the polyethylene glycol is obtained, blending the said dispersion or solution with the molten candy base in an amount of from 2-16% by wt., and forming the blend into lozenges. The Examples describe the preparation of lozenges containing acetaminophen, aluminium aspirin, salicylamide, acetylsalicylic acid, cyproheptadine tannate, 4-hexylresorcinol, phenylpropanolamine, phenylephrine hydrochloride, and d-methorphan tannate.
GB431665A 1964-02-06 1965-02-01 Medicated lozenges Expired GB1084864A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34312864A 1964-02-06 1964-02-06

Publications (1)

Publication Number Publication Date
GB1084864A true GB1084864A (en) 1967-09-27

Family

ID=23344825

Family Applications (1)

Application Number Title Priority Date Filing Date
GB431665A Expired GB1084864A (en) 1964-02-06 1965-02-01 Medicated lozenges

Country Status (1)

Country Link
GB (1) GB1084864A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1323417A1 (en) * 2001-05-10 2003-07-02 Yamanouchi Pharmaceutical Co. Ltd. Tablets quickly disintegrating in the oral cavity and process for producing the same
EP1374858A2 (en) * 2001-05-10 2004-01-02 Yamanouchi Pharmaceutical Co. Ltd. Quick-disintegrating tablet in the buccal cavity and manufacturing method thereof
WO2005023236A1 (en) * 2003-08-22 2005-03-17 Pediamed Pharmaceuticals, Inc. Phenylephrine tannate, pyrilamine tannate, and dextromethorphan tannate salts in pharmaceutical compositions
US6872405B2 (en) 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
EP1550438A2 (en) * 2003-12-16 2005-07-06 Advance Holdings Limited Method for preparing a medicated candy containing ambroxol and the thus obtained candy
WO2006092569A1 (en) 2005-03-01 2006-09-08 Reckitt Benckiser Healthcare (Uk) Limited Production process for nsaid-containing lozenges, their compositions, their medicinal use
WO2009023434A2 (en) * 2007-08-13 2009-02-19 Mcneil-Ppc, Inc. Method for stabilizing phenylephrine
GR1010679B (en) * 2023-02-03 2024-04-26 Ιουλια Κλεωνος Τσετη Pharmaceuticalcomposition of paracetamol in the form of pills or lozenges with a taste enhancer compatible with paracetamol

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002255321B2 (en) * 2001-05-10 2007-05-17 Astellas Pharma Inc. Tablets quickly disintegrating in the oral cavity and process for producing the same
EP1374858A2 (en) * 2001-05-10 2004-01-02 Yamanouchi Pharmaceutical Co. Ltd. Quick-disintegrating tablet in the buccal cavity and manufacturing method thereof
EP1374858A3 (en) * 2001-05-10 2004-05-26 Yamanouchi Pharmaceutical Co. Ltd. Quick-disintegrating tablet in the buccal cavity and manufacturing method thereof
EP1323417A4 (en) * 2001-05-10 2004-05-26 Yamanouchi Pharma Co Ltd Tablets quickly disintegrating in the oral cavity and process for producing the same
US6872405B2 (en) 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
EP1323417A1 (en) * 2001-05-10 2003-07-02 Yamanouchi Pharmaceutical Co. Ltd. Tablets quickly disintegrating in the oral cavity and process for producing the same
WO2005023236A1 (en) * 2003-08-22 2005-03-17 Pediamed Pharmaceuticals, Inc. Phenylephrine tannate, pyrilamine tannate, and dextromethorphan tannate salts in pharmaceutical compositions
EP1550438A2 (en) * 2003-12-16 2005-07-06 Advance Holdings Limited Method for preparing a medicated candy containing ambroxol and the thus obtained candy
EP1550438A3 (en) * 2003-12-16 2005-08-10 Advance Holdings Limited Method for preparing a medicated candy containing ambroxol and the thus obtained candy
KR101358687B1 (en) 2005-03-01 2014-02-07 레킷트 벵키저 헬스케어(유케이)리미티드 Production process for NSAID-containing lozenges and a pharmaceutical lozenge formulation obtained therfrom
EP1853220B1 (en) 2005-03-01 2017-08-16 Reckitt Benckiser Healthcare (UK) Limited Production process for nsaid-containing lozenges, their compositions, their medicinal use
EP3284458B1 (en) 2005-03-01 2021-06-16 Reckitt Benckiser Healthcare (UK) Limited Production process for nsaid-containing lozenges
US10933040B2 (en) 2005-03-01 2021-03-02 Reckitt Benckiser Healthcare (Uk) Limited Production process for NSAID-containing lozenges, their compositions, their medicinal use
AU2006219777B2 (en) * 2005-03-01 2010-07-01 Reckitt Benckiser Healthcare (Uk) Limited Production process for NSAID-containing lozenges, their compositions, their medicinal use
EP2210587A1 (en) * 2005-03-01 2010-07-28 Reckitt Benckiser Healthcare (UK) Limited Production process for NSAID-containing lozenges, their compositions, their medicinal use
US10328039B2 (en) 2005-03-01 2019-06-25 Reckiit Benckiser Healthcare (Uk) Limited Production process for NSAID-containing lozenges, their compositions, their medicinal use
EP3284458A1 (en) * 2005-03-01 2018-02-21 Reckitt Benckiser Healthcare (UK) Limited Production process for nsaid-containing lozenges, their compositions, their medicinal use
CN103156818A (en) * 2005-03-01 2013-06-19 利洁时保健(英国)有限公司 Production process for nsaid-containing lozenges, their compositions, their medicinal use
WO2006092569A1 (en) 2005-03-01 2006-09-08 Reckitt Benckiser Healthcare (Uk) Limited Production process for nsaid-containing lozenges, their compositions, their medicinal use
JP2008531664A (en) * 2005-03-01 2008-08-14 レキット ベンキーザー ヘルスケア (ユーケイ) リミテッド Method for producing NSAID-containing lozenge, composition thereof, medical use thereof
US8323695B2 (en) 2007-08-13 2012-12-04 Mcneil-Ppc, Inc. Method for stabilizing phenylephrine
EP2246045A1 (en) * 2007-08-13 2010-11-03 McNeil-PPC, Inc. Method for stabilizing phenylephrine
WO2009023434A3 (en) * 2007-08-13 2009-04-09 Mcneil Ppc Inc Method for stabilizing phenylephrine
WO2009023434A2 (en) * 2007-08-13 2009-02-19 Mcneil-Ppc, Inc. Method for stabilizing phenylephrine
GR1010679B (en) * 2023-02-03 2024-04-26 Ιουλια Κλεωνος Τσετη Pharmaceuticalcomposition of paracetamol in the form of pills or lozenges with a taste enhancer compatible with paracetamol

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