GB1061571A - N,n'-disubstituted piperazines and process for their manufacture - Google Patents
N,n'-disubstituted piperazines and process for their manufactureInfo
- Publication number
- GB1061571A GB1061571A GB170264A GB170264A GB1061571A GB 1061571 A GB1061571 A GB 1061571A GB 170264 A GB170264 A GB 170264A GB 170264 A GB170264 A GB 170264A GB 1061571 A GB1061571 A GB 1061571A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid addition
- phenyl
- addition salt
- converting
- free base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25104763A | 1963-01-14 | 1963-01-14 | |
| US25778463A | 1963-02-11 | 1963-02-11 | |
| US25778363A | 1963-02-11 | 1963-02-11 | |
| US27189063A | 1963-04-10 | 1963-04-10 | |
| US32133463A | 1963-11-04 | 1963-11-04 | |
| US32134263A | 1963-11-04 | 1963-11-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1061571A true GB1061571A (en) | 1967-03-15 |
Family
ID=27559375
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1053301D Active GB1053301A (nl) | 1963-01-14 | ||
| GB170264A Expired GB1061571A (en) | 1963-01-14 | 1964-01-14 | N,n'-disubstituted piperazines and process for their manufacture |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1053301D Active GB1053301A (nl) | 1963-01-14 |
Country Status (5)
| Country | Link |
|---|---|
| BE (3) | BE642429A (nl) |
| CH (5) | CH449634A (nl) |
| DE (1) | DE1232587B (nl) |
| FR (1) | FR3734M (nl) |
| GB (2) | GB1061571A (nl) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0034284A2 (en) * | 1980-02-18 | 1981-08-26 | Tanabe Seiyaku Co., Ltd. | Piperazine derivative, processes for preparing the same and therapeutic compositions containing it |
| US7485651B2 (en) | 1998-03-31 | 2009-02-03 | Acadia Pharmaceuticals, Inc. | Compounds with activity on muscarinic receptors |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5513209A (en) * | 1978-07-11 | 1980-01-30 | Synthelabo | Antidepressive made of piperazine derivative |
| FR2568878B1 (fr) * | 1984-08-07 | 1986-11-21 | Cortial | Nouveaux derives de (phenylpiperazinylethylamine ethoxy)-4 phenol, leur methode de preparation et leur application therapeutique |
| DE3715763A1 (de) * | 1987-05-12 | 1988-11-24 | Hoechst Ag | Diarylalkyl-substituierte alkylamine, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende arzneimittel |
| MXPA00009569A (es) * | 1998-03-31 | 2002-08-06 | Acadia Pharm Inc | Compuestos con actividad en receptores muscarinicos. |
-
0
- GB GB1053301D patent/GB1053301A/en active Active
-
1964
- 1964-01-09 CH CH449267A patent/CH449634A/de unknown
- 1964-01-09 CH CH449367A patent/CH449635A/de unknown
- 1964-01-09 CH CH449467A patent/CH449636A/de unknown
- 1964-01-09 CH CH22764A patent/CH449030A/de unknown
- 1964-01-09 CH CH449167A patent/CH449633A/de unknown
- 1964-01-10 DE DEC31848A patent/DE1232587B/de active Pending
- 1964-01-13 BE BE642429A patent/BE642429A/xx unknown
- 1964-01-13 BE BE642427A patent/BE642427A/xx unknown
- 1964-01-13 BE BE642428A patent/BE642428A/xx unknown
- 1964-01-14 GB GB170264A patent/GB1061571A/en not_active Expired
- 1964-04-07 FR FR969932A patent/FR3734M/fr not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0034284A2 (en) * | 1980-02-18 | 1981-08-26 | Tanabe Seiyaku Co., Ltd. | Piperazine derivative, processes for preparing the same and therapeutic compositions containing it |
| EP0034284A3 (en) * | 1980-02-18 | 1981-12-09 | Tanabe Seiyaku Co., Ltd. | Piperazine derivative and processes for preparing the same |
| US7485651B2 (en) | 1998-03-31 | 2009-02-03 | Acadia Pharmaceuticals, Inc. | Compounds with activity on muscarinic receptors |
Also Published As
| Publication number | Publication date |
|---|---|
| BE642428A (nl) | 1964-07-13 |
| CH449635A (de) | 1968-01-15 |
| BE642427A (nl) | 1964-07-13 |
| CH449636A (de) | 1968-01-15 |
| GB1053301A (nl) | |
| CH449634A (de) | 1968-01-15 |
| BE642429A (nl) | 1964-07-13 |
| FR3734M (fr) | 1965-12-06 |
| CH449030A (de) | 1967-12-31 |
| CH449633A (de) | 1968-01-15 |
| DE1232587B (de) | 1967-01-19 |
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