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GB1033484A - Process for preparing tablets containing chloral betaine - Google Patents

Process for preparing tablets containing chloral betaine

Info

Publication number
GB1033484A
GB1033484A GB1590464A GB1590464A GB1033484A GB 1033484 A GB1033484 A GB 1033484A GB 1590464 A GB1590464 A GB 1590464A GB 1590464 A GB1590464 A GB 1590464A GB 1033484 A GB1033484 A GB 1033484A
Authority
GB
United Kingdom
Prior art keywords
tablets
tablets containing
polyethylene glycols
chloral betaine
granules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1590464A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mead Johnson and Co LLC
Original Assignee
Mead Johnson and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mead Johnson and Co LLC filed Critical Mead Johnson and Co LLC
Publication of GB1033484A publication Critical patent/GB1033484A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

Tablets containing at least 90% total dry weight of chloral betaine are prepared by mixing the said agent with acacia or polyvinylpyrrolidone as a binder, granulating this mixture with aqueous gelatine solution, adjusting the free moisture in the granules to a weight percent of 0. 6 to 1. 1%, and compressing into tablets while maintaining this moisture content. Tabletting lubricants such as stearic acid, talc, high molecular weight polyethylene glycols, fatty glycerides and other edible oils, magnesium stearate, or mineral oil may be added to the granules before compressing. The tablets may be coated, with film formers such as ethyl-, methyl-, or hydroxypropylmethyl-cellulose, cellulose acetate phthalate, polyethylene glycols, shellac or alginic acid derivatives, or with sugar coatings or compression coatings.
GB1590464A 1963-06-28 1964-04-16 Process for preparing tablets containing chloral betaine Expired GB1033484A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29130063A 1963-06-28 1963-06-28

Publications (1)

Publication Number Publication Date
GB1033484A true GB1033484A (en) 1966-06-22

Family

ID=23119753

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1590464A Expired GB1033484A (en) 1963-06-28 1964-04-16 Process for preparing tablets containing chloral betaine

Country Status (1)

Country Link
GB (1) GB1033484A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235986A1 (en) * 1986-02-13 1987-09-09 Ethical Pharmaceuticals Limited Slow release formulation
EP1279433A2 (en) * 2001-06-26 2003-01-29 Glatt Ingenieurtechnik GmbH Process for coating of matrial in granular and powder form

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235986A1 (en) * 1986-02-13 1987-09-09 Ethical Pharmaceuticals Limited Slow release formulation
US4880830A (en) * 1986-02-13 1989-11-14 Ethical Pharmaceuticals Limited Slow release formulation
EP1279433A2 (en) * 2001-06-26 2003-01-29 Glatt Ingenieurtechnik GmbH Process for coating of matrial in granular and powder form
EP1279433A3 (en) * 2001-06-26 2003-07-02 Glatt Ingenieurtechnik GmbH Process for coating of matrial in granular and powder form
EP1987875A1 (en) * 2001-06-26 2008-11-05 Glatt Ingenieurtechnik GmbH Method for coating granular and powder-form materials

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