[go: up one dir, main page]

FR2963108B1 - Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin - Google Patents

Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin

Info

Publication number
FR2963108B1
FR2963108B1 FR1055973A FR1055973A FR2963108B1 FR 2963108 B1 FR2963108 B1 FR 2963108B1 FR 1055973 A FR1055973 A FR 1055973A FR 1055973 A FR1055973 A FR 1055973A FR 2963108 B1 FR2963108 B1 FR 2963108B1
Authority
FR
France
Prior art keywords
blood
evidence
kit
antigen complex
immunodiagnostic method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1055973A
Other languages
English (en)
Other versions
FR2963108A1 (fr
Inventor
Laurence Fauconnier
Yves Barbreau
Arnaud Boulet
Maha Zakhour
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diagast SAS
Original Assignee
Diagast SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1055973A priority Critical patent/FR2963108B1/fr
Application filed by Diagast SAS filed Critical Diagast SAS
Priority to EP11737928.9A priority patent/EP2596370B1/fr
Priority to TW100125771A priority patent/TW201217784A/zh
Priority to ES11737928T priority patent/ES2779043T3/es
Priority to JP2013520156A priority patent/JP2013531259A/ja
Priority to US13/810,925 priority patent/US9618518B2/en
Priority to ARP110102647A priority patent/AR082317A1/es
Priority to PCT/EP2011/062560 priority patent/WO2012010666A1/fr
Publication of FR2963108A1 publication Critical patent/FR2963108A1/fr
Application granted granted Critical
Publication of FR2963108B1 publication Critical patent/FR2963108B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/5434Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
FR1055973A 2010-07-21 2010-07-21 Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin Active FR2963108B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR1055973A FR2963108B1 (fr) 2010-07-21 2010-07-21 Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin
TW100125771A TW201217784A (en) 2010-07-21 2011-07-21 Magnetic immunodiagnostic method and kit for the demonstration of antibody/antigen complexes in erythrocyte blood grouping and phenotyping
ES11737928T ES2779043T3 (es) 2010-07-21 2011-07-21 Métodos de inmunodiagnóstico magnético y kits para la determinación de complejos de anticuerpo/antígeno en la agrupación y el fenotipado sanguíneo de eritrocitos
JP2013520156A JP2013531259A (ja) 2010-07-21 2011-07-21 赤血球の血液型判定および表現型判定における抗体/抗原複合体の実証のための磁気的免疫診断法およびキット
EP11737928.9A EP2596370B1 (fr) 2010-07-21 2011-07-21 Méthodes d'immunodiagnostic magnétique et nécessaires révélant la présence de complexes anticorps/antigènes dans le cadre du groupage et du phénotypage du sang érythrocytaire
US13/810,925 US9618518B2 (en) 2010-07-21 2011-07-21 Magnetic immunodiagnostic methods and kit for the demonstration of antibody/antigen complexes in erythrocyte blood grouping and phenotyping
ARP110102647A AR082317A1 (es) 2010-07-21 2011-07-21 Metodo de inmunodiagnostico magnetico y kit para la demostracion de complejos anticuerpo/antigeno en determinacion de grupo sanguineo y fenotipificacion de eritrocitos
PCT/EP2011/062560 WO2012010666A1 (fr) 2010-07-21 2011-07-21 Méthodes d'immunodiagnostic magnétique et nécessaires révélant la présence de complexes anticorps/antigènes dans le cadre du groupage et du phénotypage du sang érythrocytaire

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1055973A FR2963108B1 (fr) 2010-07-21 2010-07-21 Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin

Publications (2)

Publication Number Publication Date
FR2963108A1 FR2963108A1 (fr) 2012-01-27
FR2963108B1 true FR2963108B1 (fr) 2017-06-23

Family

ID=43598290

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1055973A Active FR2963108B1 (fr) 2010-07-21 2010-07-21 Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin

Country Status (8)

Country Link
US (1) US9618518B2 (fr)
EP (1) EP2596370B1 (fr)
JP (1) JP2013531259A (fr)
AR (1) AR082317A1 (fr)
ES (1) ES2779043T3 (fr)
FR (1) FR2963108B1 (fr)
TW (1) TW201217784A (fr)
WO (1) WO2012010666A1 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9182389B2 (en) * 2011-02-22 2015-11-10 Chrome Red Technologies, Llc Detection of specific antigens in a population of antigens
WO2013181149A2 (fr) * 2012-05-29 2013-12-05 Arryx, Inc. Procédés et dispositifs pour l'analyse et l'évaluation d'échantillons
FR2991689B1 (fr) * 2012-06-11 2018-04-20 Diagast Dispositif de diagnostic immuno-hematologique et utilisations
CN103344755B (zh) * 2013-07-19 2015-06-24 中国科学院苏州生物医学工程技术研究所 一种磁化醛化羊红细胞的制备方法
GB201402174D0 (en) * 2014-02-07 2014-03-26 Qbd Qs Ip Ltd Detection method
GB201403115D0 (en) * 2014-02-21 2014-04-09 Qbd Qs Ip Ltd Red blood cell detection
SG11201607582RA (en) * 2014-03-07 2016-10-28 Univ California Devices for integrating analyte extraction, concentration and detection
WO2016077558A1 (fr) * 2014-11-13 2016-05-19 T2 Biosystems, Inc. Méthodes de typage sanguin et de dépistage d'anticorps
AU2016318103B2 (en) 2015-09-04 2022-11-17 The Regents Of The University Of California Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications
EP3165920B1 (fr) * 2015-11-06 2019-07-03 imusyn GmbH & Co. KG Procede d'analyse de serum sur anti-erythrocytaires
AU2017210033B2 (en) 2016-01-21 2022-09-29 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of bacteria
CN105699666B (zh) * 2016-01-26 2018-01-09 北京中科圆融生物科技发展有限公司 超顺磁性功能颗粒、磁化红细胞及其临床应用
PL3469365T3 (pl) 2016-06-09 2023-04-03 The Regents Of The University Of California Zatężanie biomarkera i amplifikacja sygnału do zastosowania w testach immunologicznych na bazie papieru
WO2018039139A1 (fr) 2016-08-22 2018-03-01 The Regents Of The University Of California Plate-forme d'hydrogel pour concentration aqueuse à deux phases d'une cible pour améliorer sa détection
WO2018183211A1 (fr) 2017-03-27 2018-10-04 The Regents Of The University Of California Immunoessai à écoulement latéral semi-quantitatif destiné à la détection de fuites de csf
JP6289705B1 (ja) 2017-03-31 2018-03-07 Jsr株式会社 プローブ結合担体の製造方法、プローブ結合担体および標的物質を検出または分離する方法
EP3752835A1 (fr) 2018-02-16 2020-12-23 Diagast Dispositif de diagnostic in vitro comprenant des perles et ses utilisations
CN108680756A (zh) * 2018-05-21 2018-10-19 中国科学院苏州生物医学工程技术研究所 一种不完全抗体检测试剂盒及检测方法
CN109541240A (zh) * 2018-11-15 2019-03-29 上海市血液中心 一种直抗检测能力验证方法及其检测试剂盒
FR3106900B1 (fr) 2020-02-04 2024-10-04 Innobiochips Procédé de capture et d’identification d’agglutinats cellulaires pour la détection d’anticorps anti-érythrocytaires multiplexe
CN111184684B (zh) * 2020-02-08 2022-08-30 苏州大学 一种红细胞凝胶递释系统及其制备方法与应用
CN111443211B (zh) * 2020-03-04 2024-01-26 重庆大学 一种多血型系统自动检测卡及检测方法
US20220065879A1 (en) * 2020-09-01 2022-03-03 Essen Instruments, Inc. D/B/A Essen Bioscience, Inc. Automated method for direct sampling of immune cells from whole blood or other biological samples in microwell plates
CN114137230B (zh) * 2022-01-29 2022-04-29 北京大有天弘科技有限公司 一种血型不规则抗体的检测方法及其应用
CN114397464B (zh) * 2022-03-24 2022-06-10 天津德祥生物技术有限公司 一种红细胞膜碎片与载体的偶联复合物、其偶联方法和应用
CN115356477B (zh) * 2022-10-20 2023-02-10 苏州纳微生命科技有限公司 一种链霉亲和素磁珠及其制备方法和应用
CN118759163B (zh) * 2024-09-06 2024-12-06 深圳市卫光生物制品股份有限公司 一种抗a、抗b血凝素滴度测定方法
CN119409814A (zh) * 2025-01-06 2025-02-11 浙江大学滨江研究院 一种复合抗体免疫磁珠及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3175955D1 (en) 1981-02-19 1987-04-09 Hoffmann La Roche Process for the deternination of antigens or antibodies
US4672040A (en) * 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
FR2577321B1 (fr) 1985-02-08 1989-04-28 Lapierre Yves Dispositif et procede de mise en evidence d'agglutinats erythrocytaires
US4752563A (en) * 1985-11-19 1988-06-21 Coulter Corporation Monoclonal antibody for recovery of leukocytes in human peripheral blood and method of recovery employing said monoclonal antibody
ES2030667T3 (es) 1985-12-20 1992-11-16 Syntex (U.S.A.) Inc. Metodo de separacion de particulas.
DE68919565T2 (de) 1988-07-20 1995-06-29 Olympus Optical Co Immuntestverfahren unter Verwendung magnetischer Markerteilchen.
CA2028995A1 (fr) 1989-10-31 1991-05-01 Tomo Saito Immuno-essai d'agglutination indirecte et appareil utilise a cette fin
GR1002306B (el) 1990-11-09 1996-05-08 Ortho Diagnostic Systems Inc. Αναλυση και διαταξη συγκολλησεως στηλης.
GB9107030D0 (en) 1991-04-04 1991-05-22 Wellcome Found Assay
FR2679660B1 (fr) 1991-07-22 1993-11-12 Pasteur Diagnostics Procede et dispositif magnetique d'analyse immunologique sur phase solide.
WO1996009409A1 (fr) * 1994-09-20 1996-03-28 Miltenyi Biotech, Inc. Enrichissement de cellules f×tales, a partir du sang maternel
NL1003570C2 (nl) 1996-07-11 1998-01-15 Stichting Centraal Lab Methode voor antigeen- en antistofbepaling in de bloedgroepserologie.
CA2375115C (fr) * 1999-05-28 2011-05-24 Stemcell Technologies Inc. Procede de separation des cellules par utilisation de rosettes immunitaires
FR2817967B1 (fr) 2000-12-08 2003-02-28 Diagast Procede de magnetisation de marqueurs chimiques ou biologiques
CA2557819A1 (fr) * 2004-03-03 2005-09-15 The General Hospital Corporation Dispositif magnetique destine a l'isolation de cellules et de biomolecules dans un environnement microfluidique
FR2869996B1 (fr) 2004-05-05 2006-12-15 Diagast Soc Par Actions Simpli Utilisation de ferrofluides pour le phenotypage sanguin et applications derivees
DE602006018595D1 (de) * 2005-04-08 2011-01-13 Medical Discovery Partners Llc Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut
FR2892820B1 (fr) * 2005-11-03 2008-02-01 Diagast Soc Par Actions Simpli Procede magnetique d'immunodiagnostic pour la mise en evidence de complexe anticorps/antigene, en particulier de groupe sanguin

Also Published As

Publication number Publication date
ES2779043T3 (es) 2020-08-13
WO2012010666A1 (fr) 2012-01-26
US9618518B2 (en) 2017-04-11
FR2963108A1 (fr) 2012-01-27
US20130130280A1 (en) 2013-05-23
TW201217784A (en) 2012-05-01
EP2596370A1 (fr) 2013-05-29
AR082317A1 (es) 2012-11-28
JP2013531259A (ja) 2013-08-01
EP2596370B1 (fr) 2019-12-25

Similar Documents

Publication Publication Date Title
FR2963108B1 (fr) Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin
HK1219965A1 (zh) 對磷脂醯肌醇蛋白聚糖 特異的人單克隆抗體及其用途
EP2606069A4 (fr) Anticorps humanisés de la chaîne alpha des anti-récepteurs de l'interleukine-3
EP2572203A4 (fr) Isolement rapide d'anticorps monoclonaux à partir d'animaux
EP2771694A4 (fr) Anticorps monoclonaux et leurs procédés d'utilisation
EP2595657A4 (fr) Anticorps-antigènes antitumoraux et méthodes d'utilisation correspondantes
EP2794928A4 (fr) Compositions et procédés pour la détection d'analytes
EP2427479A4 (fr) Anticorps et procédés d'utilisation de ceux-ci
EP2460009A4 (fr) Dispositif pour la détection d'antigènes et applications associées
ZA201007452B (en) Anti-il-17a/il/17f cross-reactive antibodies and methods of use thereof
EP2569241A4 (fr) Procédé et système pour la limitation de droits d'accès
IL202322A0 (en) Detection of antigens carried by erythrocytes and of anti-erythrocyte antibodies
EP2542661A4 (fr) Dispositif de tri microfluidique pour la détection et l'isolement de cellules
EP2538840A4 (fr) Système dissocié d'imagerie par résonance magnétique
EP2696211A4 (fr) Capteur de champ magnétique à pont mono-puce et son procédé de préparation
DK2400298T3 (da) Enkelt B-celle-dyrkningsfremgangsmåde og specifik antistoffremstilling
EP2540743A4 (fr) Anticorps monoclonal anti-tnf-alpha entièrement humain, son procédé de préparation et son utilisation
EP2501719A4 (fr) Peptides et procédés pour la détection d'anticorps contre la maladie de lyme
EP2641914A4 (fr) Anticorps monoclonal capable de reconnaître la protéine l2 du papillomavirus humain (hpv) et procédé de mesure du titre en anticorps neutralisant le hpv l'employant
EP2693816A4 (fr) Procédé et dispositif pour la transmission d'accusés de réception de trames
EP2659270A4 (fr) Génération d'anticorps monoclonaux entiers
EP2575882A4 (fr) Anticorps monoclonaux humanisés et méthodes d'utilisation
EP2501718A4 (fr) Peptides, dispositifs, et procédés pour la détection d'anticorps anti-ehrlichia
BR112012025082A2 (pt) novos anticorpos monoclonais e método de análise imunológica de dímero-d
FR2980271B1 (fr) Procede de determination de la glycosylation d'un anticorps

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 7

PLFP Fee payment

Year of fee payment: 8

PLFP Fee payment

Year of fee payment: 9

PLFP Fee payment

Year of fee payment: 11

PLFP Fee payment

Year of fee payment: 12

PLFP Fee payment

Year of fee payment: 13

PLFP Fee payment

Year of fee payment: 14

PLFP Fee payment

Year of fee payment: 15