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FR2958942B1 - INHIBITORS OF ACCUMULATION OF SPRD TRANSCRIPTS AT S. AUREUS - Google Patents

INHIBITORS OF ACCUMULATION OF SPRD TRANSCRIPTS AT S. AUREUS

Info

Publication number
FR2958942B1
FR2958942B1 FR1052933A FR1052933A FR2958942B1 FR 2958942 B1 FR2958942 B1 FR 2958942B1 FR 1052933 A FR1052933 A FR 1052933A FR 1052933 A FR1052933 A FR 1052933A FR 2958942 B1 FR2958942 B1 FR 2958942B1
Authority
FR
France
Prior art keywords
sprd
transcripts
accumulation
aureus
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1052933A
Other languages
French (fr)
Other versions
FR2958942A1 (en
Inventor
Svetlana Chabelskaya
Brice Felden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Rennes 1
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Universite de Rennes 1
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Rennes 1, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Universite de Rennes 1
Priority to FR1052933A priority Critical patent/FR2958942B1/en
Priority to PCT/EP2011/056052 priority patent/WO2011128445A1/en
Publication of FR2958942A1 publication Critical patent/FR2958942A1/en
Application granted granted Critical
Publication of FR2958942B1 publication Critical patent/FR2958942B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne notamment un inhibiteur de l'accumulation des transcrits SprD et un procédé pour la sélection ou l'identification in vitro ou ex vivo de composés pour la prévention et/ou le traitement d'une infection staphylococcique.The invention relates in particular to an inhibitor of the accumulation of SprD transcripts and to a method for the selection or identification in vitro or ex vivo of compounds for the prevention and / or treatment of a staphylococcal infection.

FR1052933A 2010-04-16 2010-04-16 INHIBITORS OF ACCUMULATION OF SPRD TRANSCRIPTS AT S. AUREUS Expired - Fee Related FR2958942B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1052933A FR2958942B1 (en) 2010-04-16 2010-04-16 INHIBITORS OF ACCUMULATION OF SPRD TRANSCRIPTS AT S. AUREUS
PCT/EP2011/056052 WO2011128445A1 (en) 2010-04-16 2011-04-15 Inhibitors of the accumulation of sprd transcripts in s. aureus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1052933A FR2958942B1 (en) 2010-04-16 2010-04-16 INHIBITORS OF ACCUMULATION OF SPRD TRANSCRIPTS AT S. AUREUS

Publications (2)

Publication Number Publication Date
FR2958942A1 FR2958942A1 (en) 2011-10-21
FR2958942B1 true FR2958942B1 (en) 2015-04-17

Family

ID=43414843

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1052933A Expired - Fee Related FR2958942B1 (en) 2010-04-16 2010-04-16 INHIBITORS OF ACCUMULATION OF SPRD TRANSCRIPTS AT S. AUREUS

Country Status (2)

Country Link
FR (1) FR2958942B1 (en)
WO (1) WO2011128445A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ543855A (en) * 2003-06-05 2008-04-30 Wyeth Corp Nucleic acid arrays for detecting multiple strains of a non-viral species
FR2935146B1 (en) * 2008-08-22 2013-03-01 Univ Rennes POLYNUCLEOTIDES REGULATING NEGATIVELY THE EXPRESSION OF SBI PROTEIN

Also Published As

Publication number Publication date
WO2011128445A1 (en) 2011-10-20
FR2958942A1 (en) 2011-10-21

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