FR2936255B1 - Modulateurs de fzd2 dans le traitement de l'alopecie - Google Patents
Modulateurs de fzd2 dans le traitement de l'alopecieInfo
- Publication number
- FR2936255B1 FR2936255B1 FR0856315A FR0856315A FR2936255B1 FR 2936255 B1 FR2936255 B1 FR 2936255B1 FR 0856315 A FR0856315 A FR 0856315A FR 0856315 A FR0856315 A FR 0856315A FR 2936255 B1 FR2936255 B1 FR 2936255B1
- Authority
- FR
- France
- Prior art keywords
- alopecia
- treatment
- fzd2
- modulators
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 201000004384 Alopecia Diseases 0.000 title abstract 3
- 102100021265 Frizzled-2 Human genes 0.000 title abstract 3
- 231100000360 alopecia Toxicity 0.000 title abstract 3
- 101000819477 Homo sapiens Frizzled-2 Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 101710140946 Frizzled-2 Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- 102000027257 transmembrane receptors Human genes 0.000 abstract 2
- 108091008578 transmembrane receptors Proteins 0.000 abstract 2
- 238000009109 curative therapy Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0856315A FR2936255B1 (fr) | 2008-09-19 | 2008-09-19 | Modulateurs de fzd2 dans le traitement de l'alopecie |
CA2737993A CA2737993A1 (fr) | 2008-09-19 | 2009-09-21 | Modulateurs de fzd2 dans le traitement de l'alopecie |
US13/120,103 US20110224243A1 (en) | 2008-09-19 | 2009-09-21 | FZD2 Molulators in the Treatment of Alopecia |
PCT/FR2009/051770 WO2010031979A1 (fr) | 2008-09-19 | 2009-09-21 | Modulateurs de fzd2 dans le traitement de l'alopecie |
EP09747890A EP2329036A1 (fr) | 2008-09-19 | 2009-09-21 | Modulateurs de fzd2 dans le traitement de l'alopecie |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0856315A FR2936255B1 (fr) | 2008-09-19 | 2008-09-19 | Modulateurs de fzd2 dans le traitement de l'alopecie |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2936255A1 FR2936255A1 (fr) | 2010-03-26 |
FR2936255B1 true FR2936255B1 (fr) | 2010-10-15 |
Family
ID=40568269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0856315A Expired - Fee Related FR2936255B1 (fr) | 2008-09-19 | 2008-09-19 | Modulateurs de fzd2 dans le traitement de l'alopecie |
Country Status (5)
Country | Link |
---|---|
US (1) | US20110224243A1 (fr) |
EP (1) | EP2329036A1 (fr) |
CA (1) | CA2737993A1 (fr) |
FR (1) | FR2936255B1 (fr) |
WO (1) | WO2010031979A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007133250A2 (fr) | 2005-10-31 | 2007-11-22 | Austin Gurney | Compositions et procédés de diagnostic et de traitement du cancer |
US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
TWI506037B (zh) | 2008-09-26 | 2015-11-01 | Oncomed Pharm Inc | 捲曲結合劑類及彼等之用途 |
TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Wnt拮抗劑及治療和篩選方法 |
JP2013530929A (ja) | 2010-04-01 | 2013-08-01 | オンコメッド ファーマシューティカルズ インコーポレイテッド | frizzled結合剤およびその使用 |
EP2720721B1 (fr) | 2011-06-17 | 2017-08-30 | President and Fellows of Harvard College | Frizzled 2 en tant que cible pour des anticorps thérapeutiques dans le traitement du cancer |
WO2014066328A1 (fr) | 2012-10-23 | 2014-05-01 | Oncomed Pharmaceuticals, Inc. | Méthodes de traitement de tumeurs neuro-endocrines à l'aide d'agents liants de parcours wnt |
WO2014121196A1 (fr) | 2013-02-04 | 2014-08-07 | Oncomed Pharmaceuticals, Inc. | Méthodes et surveillance de traitement par un inhibiteur de la voie wnt |
US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001253012B2 (en) * | 2000-03-31 | 2006-02-23 | The General Hospital Corporation | Methods of modulating hair growth |
EP1743022A4 (fr) * | 2004-02-27 | 2008-02-06 | Gen Hospital Corp | Procedes et compositions pour la croissance capillaire |
-
2008
- 2008-09-19 FR FR0856315A patent/FR2936255B1/fr not_active Expired - Fee Related
-
2009
- 2009-09-21 WO PCT/FR2009/051770 patent/WO2010031979A1/fr active Application Filing
- 2009-09-21 US US13/120,103 patent/US20110224243A1/en not_active Abandoned
- 2009-09-21 EP EP09747890A patent/EP2329036A1/fr not_active Withdrawn
- 2009-09-21 CA CA2737993A patent/CA2737993A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2329036A1 (fr) | 2011-06-08 |
US20110224243A1 (en) | 2011-09-15 |
CA2737993A1 (fr) | 2010-03-25 |
WO2010031979A1 (fr) | 2010-03-25 |
FR2936255A1 (fr) | 2010-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20130531 |