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FR2935387B1 - Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine - Google Patents

Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine

Info

Publication number
FR2935387B1
FR2935387B1 FR0804705A FR0804705A FR2935387B1 FR 2935387 B1 FR2935387 B1 FR 2935387B1 FR 0804705 A FR0804705 A FR 0804705A FR 0804705 A FR0804705 A FR 0804705A FR 2935387 B1 FR2935387 B1 FR 2935387B1
Authority
FR
France
Prior art keywords
hexadecasaccharides
covalent binding
antithrombotic activity
amino chain
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0804705A
Other languages
English (en)
Other versions
FR2935387A1 (fr
Inventor
Marie Claude Rouchon
Joseph Michael Schofield
Dave Smith
Patrick Soubayrol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to FR0804705A priority Critical patent/FR2935387B1/fr
Priority to JP2011524424A priority patent/JP2012500885A/ja
Priority to US13/060,745 priority patent/US20110212907A1/en
Priority to PCT/FR2009/001024 priority patent/WO2010023375A1/fr
Priority to EP09737026A priority patent/EP2328936A1/fr
Publication of FR2935387A1 publication Critical patent/FR2935387A1/fr
Application granted granted Critical
Publication of FR2935387B1 publication Critical patent/FR2935387B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FR0804705A 2008-08-26 2008-08-26 Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine Expired - Fee Related FR2935387B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0804705A FR2935387B1 (fr) 2008-08-26 2008-08-26 Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine
JP2011524424A JP2012500885A (ja) 2008-08-26 2009-08-24 共有結合およびアミノ鎖を含む抗トロンビン活性を有する十六糖
US13/060,745 US20110212907A1 (en) 2008-08-26 2009-08-24 Hexadecasaccharides with antithrombotic activity, including a covalent bond and an amino chain
PCT/FR2009/001024 WO2010023375A1 (fr) 2008-08-26 2009-08-24 Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine
EP09737026A EP2328936A1 (fr) 2008-08-26 2009-08-24 Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0804705A FR2935387B1 (fr) 2008-08-26 2008-08-26 Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine

Publications (2)

Publication Number Publication Date
FR2935387A1 FR2935387A1 (fr) 2010-03-05
FR2935387B1 true FR2935387B1 (fr) 2010-09-10

Family

ID=40513857

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0804705A Expired - Fee Related FR2935387B1 (fr) 2008-08-26 2008-08-26 Hexadecasaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine

Country Status (5)

Country Link
US (1) US20110212907A1 (fr)
EP (1) EP2328936A1 (fr)
JP (1) JP2012500885A (fr)
FR (1) FR2935387B1 (fr)
WO (1) WO2010023375A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2970969B1 (fr) * 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2874924B1 (fr) * 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique

Also Published As

Publication number Publication date
JP2012500885A (ja) 2012-01-12
FR2935387A1 (fr) 2010-03-05
US20110212907A1 (en) 2011-09-01
EP2328936A1 (fr) 2011-06-08
WO2010023375A1 (fr) 2010-03-04

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20130430