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FR2831186B1 - Production d'heparine a partir de cultures de mastocytes - Google Patents

Production d'heparine a partir de cultures de mastocytes

Info

Publication number
FR2831186B1
FR2831186B1 FR0113606A FR0113606A FR2831186B1 FR 2831186 B1 FR2831186 B1 FR 2831186B1 FR 0113606 A FR0113606 A FR 0113606A FR 0113606 A FR0113606 A FR 0113606A FR 2831186 B1 FR2831186 B1 FR 2831186B1
Authority
FR
France
Prior art keywords
mastocyte
heparin
crops
production
mastocyte crops
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0113606A
Other languages
English (en)
Other versions
FR2831186A1 (fr
Inventor
Pierre Cans
Jean Marc Guillaume
Helene Monique Marie Rigal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to FR0113606A priority Critical patent/FR2831186B1/fr
Priority to ARP020103974A priority patent/AR036915A1/es
Priority to CA002462714A priority patent/CA2462714A1/fr
Priority to PCT/FR2002/003617 priority patent/WO2003035886A2/fr
Priority to HU0401794A priority patent/HUP0401794A2/hu
Priority to NZ532414A priority patent/NZ532414A/en
Priority to KR10-2004-7005914A priority patent/KR20040071127A/ko
Priority to EP02793179A priority patent/EP1438415A2/fr
Priority to MXPA04003740A priority patent/MXPA04003740A/es
Priority to BR0213478-0A priority patent/BR0213478A/pt
Priority to PL02368599A priority patent/PL368599A1/xx
Priority to JP2003538386A priority patent/JP2005506092A/ja
Priority to CNA028210166A priority patent/CN1575341A/zh
Priority to IL16106602A priority patent/IL161066A0/xx
Priority to US10/492,200 priority patent/US20050042733A1/en
Publication of FR2831186A1 publication Critical patent/FR2831186A1/fr
Priority to ZA200402304A priority patent/ZA200402304B/xx
Priority to NO20041633A priority patent/NO20041633L/no
Priority to CO04036595A priority patent/CO5570711A2/es
Application granted granted Critical
Publication of FR2831186B1 publication Critical patent/FR2831186B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR0113606A 2001-10-22 2001-10-22 Production d'heparine a partir de cultures de mastocytes Expired - Fee Related FR2831186B1 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR0113606A FR2831186B1 (fr) 2001-10-22 2001-10-22 Production d'heparine a partir de cultures de mastocytes
ARP020103974A AR036915A1 (es) 2001-10-22 2002-10-21 Produccion de heparina a partir de cultivos de mastocitos
IL16106602A IL161066A0 (en) 2001-10-22 2002-10-22 Method for preparing heparin from mast cell cultures
HU0401794A HUP0401794A2 (hu) 2001-10-22 2002-10-22 Eljárás heparin előállítására, hízósejttenyészetekből kiindulva
NZ532414A NZ532414A (en) 2001-10-22 2002-10-22 Method for preparing heparin form mast cell cultures
KR10-2004-7005914A KR20040071127A (ko) 2001-10-22 2002-10-22 비만세포 배양물로 부터 헤파린의 제조방법
EP02793179A EP1438415A2 (fr) 2001-10-22 2002-10-22 Preparation d'heparine a partir de cultures de mastocytes
MXPA04003740A MXPA04003740A (es) 2001-10-22 2002-10-22 Metodo para prerarar heparina de cultivos de mastocitos.
BR0213478-0A BR0213478A (pt) 2001-10-22 2002-10-22 Processo de produção de heparina, e, preparação de heparina
PL02368599A PL368599A1 (en) 2001-10-22 2002-10-22 Method for preparing heparin from mast cell cultures
CA002462714A CA2462714A1 (fr) 2001-10-22 2002-10-22 Preparation d'heparine a partir de cultures de mastocytes
CNA028210166A CN1575341A (zh) 2001-10-22 2002-10-22 从肥大细胞培养物制备肝素的方法
PCT/FR2002/003617 WO2003035886A2 (fr) 2001-10-22 2002-10-22 Preparation d'heparine a partir de cultures de mastocytes
US10/492,200 US20050042733A1 (en) 2001-10-22 2002-10-22 Method for preparing heparin from mast cell cultures
JP2003538386A JP2005506092A (ja) 2001-10-22 2002-10-22 肥満細胞培養物からヘパリンを製造する方法。
ZA200402304A ZA200402304B (en) 2001-10-22 2004-03-24 Method for preparing heparin from mast cell cultures.
NO20041633A NO20041633L (no) 2001-10-22 2004-04-21 Fremgangsmate for fremstilling av heparin fra mastcelle kulturer
CO04036595A CO5570711A2 (es) 2001-10-22 2004-04-21 Metodo para preparar heparina de cultivos de mastocitos

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0113606A FR2831186B1 (fr) 2001-10-22 2001-10-22 Production d'heparine a partir de cultures de mastocytes

Publications (2)

Publication Number Publication Date
FR2831186A1 FR2831186A1 (fr) 2003-04-25
FR2831186B1 true FR2831186B1 (fr) 2004-06-18

Family

ID=8868558

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0113606A Expired - Fee Related FR2831186B1 (fr) 2001-10-22 2001-10-22 Production d'heparine a partir de cultures de mastocytes

Country Status (18)

Country Link
US (1) US20050042733A1 (fr)
EP (1) EP1438415A2 (fr)
JP (1) JP2005506092A (fr)
KR (1) KR20040071127A (fr)
CN (1) CN1575341A (fr)
AR (1) AR036915A1 (fr)
BR (1) BR0213478A (fr)
CA (1) CA2462714A1 (fr)
CO (1) CO5570711A2 (fr)
FR (1) FR2831186B1 (fr)
HU (1) HUP0401794A2 (fr)
IL (1) IL161066A0 (fr)
MX (1) MXPA04003740A (fr)
NO (1) NO20041633L (fr)
NZ (1) NZ532414A (fr)
PL (1) PL368599A1 (fr)
WO (1) WO2003035886A2 (fr)
ZA (1) ZA200402304B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2853663B1 (fr) * 2003-04-14 2007-08-31 Aventis Pharma Sa Procede d'obtention de lignees de mastocytes a partir de tissus de porcs et procede de production de molecules de type heparine
FR2876386B1 (fr) * 2004-10-12 2007-04-06 Aventis Pharma Sa Lignees de mastocytes porcins produisant des molecules de type heparine
KR100688553B1 (ko) * 2005-06-22 2007-03-02 삼성전자주식회사 코어 사이즈를 감소시킨 반도체 메모리 장치
KR101447123B1 (ko) * 2014-02-27 2014-10-06 박상협 헤파린의 추출 방법
KR102104367B1 (ko) 2019-09-02 2020-04-24 팜앤바이오 주식회사 헤파린나트륨의 제조장치 및 제조방법
CN111979193A (zh) * 2019-09-27 2020-11-24 云南洛宇生物科技有限公司 大鼠骨髓源肥大细胞培养方法
CN110592165B (zh) * 2019-10-18 2021-04-27 福州大学 燕窝中硫酸乙酰肝素/肝素的提取方法与结构解析

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3016331A (en) * 1960-01-28 1962-01-09 Ormonoterapia Richter Spa Purification of heparin
WO1990014418A1 (fr) * 1989-05-19 1990-11-29 The Uab Research Foundation Lignees cellulaires de mastocytome murine produisant l'heparine
ES2108566T3 (es) * 1993-12-10 1997-12-16 Genentech Inc Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos.
FI974321A0 (fi) * 1997-11-25 1997-11-25 Jenny Ja Antti Wihurin Rahasto Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa
US6596705B1 (en) * 1998-02-09 2003-07-22 The Regents Of The University Of California Inhibition of L-selectin and P-selection mediated binding using heparin

Also Published As

Publication number Publication date
NO20041633L (no) 2004-04-21
AR036915A1 (es) 2004-10-13
BR0213478A (pt) 2004-11-03
CO5570711A2 (es) 2005-10-31
US20050042733A1 (en) 2005-02-24
IL161066A0 (en) 2004-08-31
JP2005506092A (ja) 2005-03-03
WO2003035886A2 (fr) 2003-05-01
HUP0401794A2 (hu) 2004-11-29
NZ532414A (en) 2006-12-22
CN1575341A (zh) 2005-02-02
FR2831186A1 (fr) 2003-04-25
EP1438415A2 (fr) 2004-07-21
KR20040071127A (ko) 2004-08-11
CA2462714A1 (fr) 2003-05-01
WO2003035886A3 (fr) 2004-02-26
PL368599A1 (en) 2005-04-04
MXPA04003740A (es) 2005-06-20
ZA200402304B (en) 2004-10-07

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20090630