[go: up one dir, main page]

FR2734839B1 - DNA SEQUENCE ENCODING AN A. PROTEIN. THALIANA HAVING DELTA-5,7 STEROL ACTIVITY, DELTA-7 REDUCTASE, DELTA-7RED PROTEIN, PRODUCTION PROCESS, TRANSFORMED YEAST STRAINS, APPLICATIONS. - Google Patents

DNA SEQUENCE ENCODING AN A. PROTEIN. THALIANA HAVING DELTA-5,7 STEROL ACTIVITY, DELTA-7 REDUCTASE, DELTA-7RED PROTEIN, PRODUCTION PROCESS, TRANSFORMED YEAST STRAINS, APPLICATIONS.

Info

Publication number
FR2734839B1
FR2734839B1 FR9506517A FR9506517A FR2734839B1 FR 2734839 B1 FR2734839 B1 FR 2734839B1 FR 9506517 A FR9506517 A FR 9506517A FR 9506517 A FR9506517 A FR 9506517A FR 2734839 B1 FR2734839 B1 FR 2734839B1
Authority
FR
France
Prior art keywords
delta
protein
thaliana
reductase
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9506517A
Other languages
French (fr)
Other versions
FR2734839A1 (en
Inventor
Xavier Chenivesse
Catherine Duport
Eric Lecain
Denis Pompon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR9506517A priority Critical patent/FR2734839B1/en
Priority to IL11687296A priority patent/IL116872A/en
Priority to IL16247696A priority patent/IL162476A/en
Priority to US08/601,435 priority patent/US5759801A/en
Priority to UA96020528A priority patent/UA72172C2/en
Priority to SK188-96A priority patent/SK283656B6/en
Priority to AT96400301T priority patent/ATE457354T1/en
Priority to DE69638123T priority patent/DE69638123D1/en
Priority to CN2004100488331A priority patent/CN1664107A/en
Priority to CZ1996432A priority patent/CZ294860B6/en
Priority to KR1019960003564A priority patent/KR100422293B1/en
Priority to ES96400301T priority patent/ES2339833T3/en
Priority to EP96400301A priority patent/EP0727489B1/en
Priority to RU96102857/13A priority patent/RU2242517C2/en
Priority to CA2169524A priority patent/CA2169524C/en
Priority to FI960663A priority patent/FI120877B/en
Priority to SI9630775T priority patent/SI0727489T1/en
Priority to ARP960101380A priority patent/AR003407A1/en
Priority to PT96400301T priority patent/PT727489E/en
Priority to CN961060778A priority patent/CN1216995C/en
Priority to DK96400301.6T priority patent/DK0727489T3/en
Priority to HU9600325A priority patent/HU220587B1/en
Priority to BRPI9600729 priority patent/BRPI9600729B8/en
Priority to PL96312828A priority patent/PL185569B1/en
Priority to HR960078A priority patent/HRP960078B1/en
Priority to TR96/00116A priority patent/TR199600116A2/en
Priority to JP05079896A priority patent/JP4082469B2/en
Publication of FR2734839A1 publication Critical patent/FR2734839A1/en
Priority to US08/783,202 priority patent/US5989881A/en
Application granted granted Critical
Publication of FR2734839B1 publication Critical patent/FR2734839B1/en
Priority to US08/931,047 priority patent/US5965417A/en
Priority to IL16247704A priority patent/IL162477A0/en
Priority to IL16247604A priority patent/IL162476A0/en
Priority to ARP060102688A priority patent/AR053931A2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/02—Dehydrogenating; Dehydroxylating

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR9506517A 1995-02-15 1995-06-01 DNA SEQUENCE ENCODING AN A. PROTEIN. THALIANA HAVING DELTA-5,7 STEROL ACTIVITY, DELTA-7 REDUCTASE, DELTA-7RED PROTEIN, PRODUCTION PROCESS, TRANSFORMED YEAST STRAINS, APPLICATIONS. Expired - Lifetime FR2734839B1 (en)

Priority Applications (32)

Application Number Priority Date Filing Date Title
FR9506517A FR2734839B1 (en) 1995-06-01 1995-06-01 DNA SEQUENCE ENCODING AN A. PROTEIN. THALIANA HAVING DELTA-5,7 STEROL ACTIVITY, DELTA-7 REDUCTASE, DELTA-7RED PROTEIN, PRODUCTION PROCESS, TRANSFORMED YEAST STRAINS, APPLICATIONS.
IL11687296A IL116872A (en) 1995-02-15 1996-01-23 Delta-5, 7 sterol reductase from arabidopsis thaliana
IL16247696A IL162476A (en) 1995-02-15 1996-01-23 Arabidopsis thaliana proteins having delta -5,7- sterol - delta -7- reductase activity
US08/601,435 US5759801A (en) 1995-02-15 1996-02-12 Δ5,7 -sterol reductase from arabidopsis thaliana
SK188-96A SK283656B6 (en) 1995-02-15 1996-02-13 DNA sequence coding for an A. thaliana protein with delta-5,7-sterol-delta-7-reductase, the protein, process for the production, transformed yeast-strains and use
UA96020528A UA72172C2 (en) 1995-02-15 1996-02-13 Nucleic acid sequence having delta-5,7 sterol, delta-7 reductase activity, a method for producing protein, a method for recovery of sterols unsaturated at the position с-7, a method for producing pregnenolone, transformated strain saccaromyces cerevisiae accummulating free and etherificated pregnenolone and a method for revealing the lack of delta-5,7 sterol, delta-7 reductase
HU9600325A HU220587B1 (en) 1995-02-15 1996-02-14 Dna sequence of a. thaliana, delta-7-red protein, process for producing thereof, yeats strains transformed by this dna and use thereof
CN2004100488331A CN1664107A (en) 1995-02-15 1996-02-14 DNA sequence coding for an a. thaliana protein with delta-5,7-sterol-delta-7-reductase, the protein, process for the production, transformed yeast-strains and use
CZ1996432A CZ294860B6 (en) 1995-02-15 1996-02-14 DNA sequence encoding A. thaliana protein exhibiting delta-5,7 sterol, delta-7 reductase activity, the protein delta-7-Red, A. thaliana protein, process of their preparation, strain structures of transformed yeast and application thereof
KR1019960003564A KR100422293B1 (en) 1995-02-15 1996-02-14 DNA Sequence Coding for a Protein of A. Thaliana having a Delta-5,7 Sterol,Delta-7 Reductase Activity, Delta7-Red Protein, Production Process, Strains of Transformed Yeasts, Uses
ES96400301T ES2339833T3 (en) 1995-02-15 1996-02-14 DNA SEQUENCE CODING A PROTEIN OF A. THALIANA THAT HAS AN ACTIVITY DELTA-5,7-ESTEROL-DELTA-7-REDUCTASA, THE PROTEIN DELTA-7-RED, PRODUCTION PROCEDURE, THE LIFTS OF TRANSFORMED LEAVES, APPLICATIONS.
EP96400301A EP0727489B1 (en) 1995-02-15 1996-02-14 DNA sequence coding for an A. thaliana protein with delta-5,7-sterol-delta-7-reductase activity, the protein, process for the production, transformed yeast-strains and use
RU96102857/13A RU2242517C2 (en) 1995-02-15 1996-02-14 Nucleic acid sequence encoding protein eliciting delta-5,7-sterol,delta-7 reductase activity (variants), protein from arabidopsis thaliana eliciting indicated activity (variants), expression vector, method for cloning nucleic acid, diagnostic probe, method for preparing protein, method for reducing sterol (variants), method for preparing pregnenolone (variants), transformed yeast strain and method for detecting insufficiency of delta-5,7-sterol,delta-7 reductase
CA2169524A CA2169524C (en) 1995-02-15 1996-02-14 Dna sequence coding for an a.thaliana protein with delta-5,7 sterol, delta-7 reductase, delta-7-red protein activity, process for producing the same, transformed yeast strains, uses
FI960663A FI120877B (en) 1995-02-15 1996-02-14 DNA sequence encoding an A. thaliana protein with delta-5,7-sterol, delta-7 reductase activity, i.e. delta-7-Red protein, process for its preparation, altered yeast strains and applications
SI9630775T SI0727489T1 (en) 1995-02-15 1996-02-14 DNA sequence coding for an A. thaliana protein with delta-5,7-sterol-delta-7-reductase activity, the protein, process for the production, transformed yeast-strains and use
AT96400301T ATE457354T1 (en) 1995-02-15 1996-02-14 DNA SEQUENCE ENCODING A. THALIANA PROTEIN HAVING DELTA-5,7-STEROL-DELTA-7 REDUCTASE ACTIVITY, THE PROTEIN, METHOD OF PREPARATION, TRANSFORMED YEAST STRAINS AND USES
PT96400301T PT727489E (en) 1995-02-15 1996-02-14 Dna sequence coding for an a. thaliana protein with delta-5,7-sterol-delta-7-reductase activity, the protein, process for the production, transformed yeast-strains and use
CN961060778A CN1216995C (en) 1995-02-15 1996-02-14 DNA Sequence Coding for protein of A. thaliana having delta-5,7 terol, delta-7 reductase activity, delta T-red protein, production process strains of transformed yeasts uses
DK96400301.6T DK0727489T3 (en) 1995-02-15 1996-02-14 DNA sequence encoding an A. thaliana protein with delta-5,7-sterol, delta-7 reductase activity, delta-7Red protein, method of preparation, transformed yeast strains, uses
DE69638123T DE69638123D1 (en) 1995-02-15 1996-02-14 For an A. thaliana protein-encoding DNA sequence having delta-5,7-sterol-delta-7 reductase activity, the protein, methods of production, transformed yeast strains and uses
BRPI9600729 BRPI9600729B8 (en) 1995-02-15 1996-02-14 expression vector, transgenic microorganism, process for cloning a nucleic acid and process for preparing a protein and transformed yeast strain
ARP960101380A AR003407A1 (en) 1995-02-15 1996-02-14 CLONING PROCEDURE OF A NUCLEIC ACID CODING A PROTEIN WITH ACTIVITY OF DELTA-5,7-STEROL, DELTA-7-REDUCTASE, PROTEIN PREPARATION PROCEDURE, IN VITRO REDUCTION PROCEDURE OF AN UNSATURATED STEROL, PREGNOLINE PRODUCTION PROCEDURE , TRANSFORMED YEAST STRAIN AND IN VITRO DIAGNOSTIC METHOD FOR THE DETECTION OF DEFICIENCY OF DELTA-5, 7-STEROL, DELTA-7-REDUCTASE
PL96312828A PL185569B1 (en) 1995-02-15 1996-02-15 Nucleic acid sequence for encoding a protein a. thaliana of delta-7 activity of delta-5,7-sterole reductase, method of cloning such nucleic acid, delta-7red protein, method of obtaining such prote
HR960078A HRP960078B1 (en) 1995-02-15 1996-02-15 Dna sequence coding for a protein of a. thaliana having a delta-5, 7 sterol, delta- 7 reductase activity, delta-7-red protein, production process, strains of transformed yeasts, uses
TR96/00116A TR199600116A2 (en) 1995-02-15 1996-02-15 An a having a delta-5.7 sterol, delta-7 reductase activity, delta 7-red protein. DNA sequence coding, production process, transformed yeast type, uses for the transplanted protein.
JP05079896A JP4082469B2 (en) 1995-02-15 1996-02-15 A. having delta-5,7 sterol, delta-7 reductase activity DNA sequence encoding Thaliana protein, delta 7-Red protein, production method, transformed yeast strain, and utilization
US08/783,202 US5989881A (en) 1995-02-15 1997-01-14 Nucleic acid molecules encoding delta-5,7-sterol, delta-7 reductase from arabidopsis thaliana
US08/931,047 US5965417A (en) 1995-02-15 1997-09-16 Arabidepsi thaliana proteins having Δ-5,7-sterol-Δ-7-reductase activity
IL16247604A IL162476A0 (en) 1995-02-15 2004-06-10 Arabidopsi thaliana proteins havingdelta-5,7-sterol-delta-7-reductase activity
IL16247704A IL162477A0 (en) 1995-02-15 2004-06-10 Nucleic acid molecules encoding delta-5,7-sterol, delta-7 reductase from arabidopsis thaliana
ARP060102688A AR053931A2 (en) 1995-02-15 2006-06-22 DNA SEQUENCE CODING A PROTEIN OF A. THALIANA THAT HAS ACTIVITY OF DELTA -5,7-ESTEROL, DELTA-7-REDUCTASE, PROTEIN DELTA-7RED

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9506517A FR2734839B1 (en) 1995-06-01 1995-06-01 DNA SEQUENCE ENCODING AN A. PROTEIN. THALIANA HAVING DELTA-5,7 STEROL ACTIVITY, DELTA-7 REDUCTASE, DELTA-7RED PROTEIN, PRODUCTION PROCESS, TRANSFORMED YEAST STRAINS, APPLICATIONS.

Publications (2)

Publication Number Publication Date
FR2734839A1 FR2734839A1 (en) 1996-12-06
FR2734839B1 true FR2734839B1 (en) 1997-07-04

Family

ID=9479580

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9506517A Expired - Lifetime FR2734839B1 (en) 1995-02-15 1995-06-01 DNA SEQUENCE ENCODING AN A. PROTEIN. THALIANA HAVING DELTA-5,7 STEROL ACTIVITY, DELTA-7 REDUCTASE, DELTA-7RED PROTEIN, PRODUCTION PROCESS, TRANSFORMED YEAST STRAINS, APPLICATIONS.

Country Status (1)

Country Link
FR (1) FR2734839B1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021098506A1 (en) * 2019-11-18 2021-05-27 沈阳博泰生物制药有限公司 STEROID 5β REDUCTASE VARIANT AND APPLICATION THEREFOR
CN113151317A (en) * 2021-05-26 2021-07-23 云南中烟工业有限责任公司 Tobacco delta (24) -sterol reductase gene and application thereof

Also Published As

Publication number Publication date
FR2734839A1 (en) 1996-12-06

Similar Documents

Publication Publication Date Title
FR2736927B1 (en) ENZYMES HAVING AMIDASE ACTIVITY, GENETIC TOOLS AND HOST MICROORGANISMS FOR OBTAINING SAME AND HYDROLYSIS PROCESS USING THE SAME
AU5001496A (en) Introduction of dna into bacillus strains by conjugation
CA2153898A1 (en) Method for generating single-stranded dna molecules
EP1602725A3 (en) Abasic-nucleotide containing enzymatic nucleic acid
AU7839594A (en) Strategy for the production of rna from immobilized templates
WO2000012726A3 (en) Rationally designed heparinases derived from heparinase i and ii
HUP9600325A1 (en) Dna sequence coding for delta-7-red protein of a. thaliana having a delta-5,7 sterol, delta-7 reductase activity, delta-7-red protein, production process, strains of transformed yeasts and their uses
WO1997003192A3 (en) Chromosome 1 gene and gene products related to alzheimer's disease
AU6761496A (en) Computational analysis of nucleic acid information defines bnding sites
EP0733709A3 (en) Mutated farnesyldiphosphate synthase capable of synthesizing geranylgeranyldiphosphate and gene coding therefor
AU2001267175A1 (en) Modular approach to on-line synthesis, drug discovery and biochemical transformations using immobilized enzyme reactors
FR2734839B1 (en) DNA SEQUENCE ENCODING AN A. PROTEIN. THALIANA HAVING DELTA-5,7 STEROL ACTIVITY, DELTA-7 REDUCTASE, DELTA-7RED PROTEIN, PRODUCTION PROCESS, TRANSFORMED YEAST STRAINS, APPLICATIONS.
FR2764303B1 (en) ASPARTASE ACTIVITY PROTEIN, DNA ENCODING THE SAME, DNA-CONTAINING PLASMID AND PROCESS FOR PRODUCING THE PROTEIN AND L-ASPARTIC ACID
CA2316113A1 (en) Method for nucleic acid purification using iodine
FR2730494B1 (en) DNA SEQUENCE ENCODING AN A. PROTEIN. THALIANA HAVING DELTA-5,7 STEROL ACTIVITY, DELTA-7 REDUCTASE, DELTA7-RED PROTEIN, PRODUCTION PROCESS, TRANSFORMED YEAST STRAINS, APPLICATIONS
WO1999036432A3 (en) Orotidine 5'-phosphate decarboxylase-gene, gene construct containing said gene and the utilization thereof
FR2708936B1 (en) Nitrile hydratase enzymes, genetic tools and host microorganisms for their production and hydrolysis process using said enzymes.
EP0748868A3 (en) Ceramide glucosyltransferase
AU5810296A (en) Process for obtaining acyloins, pyruvate decarboxylases suitable therefor and their production and DNA sequences of the PDC gene coding them
WO1997042343A3 (en) Teichoic acid enzymes and assays
CA2055698A1 (en) Peroxidase gene of microbial origin
FR2732344B1 (en) OLIGONUCLEOTIDES WITH CROSS-COALENT BINDING, PREPARATION METHOD AND SYNTHON USEFUL IN THE PROCESS
FR2763523B1 (en) METHOD FOR MANUFACTURING A FLAT OR TRONCONIC ANNULAR PART, AND PART OBTAINED BY THIS PROCESS
MY136784A (en) Global regulators of bacterial pathogenic genes as targets for engineering disease resistance
FR2729970B1 (en) DNA FRAGMENT, VECTOR, CORYNEFORMED BACTERIA AND PROCESS FOR PRODUCING L-AMINO ACIDS OR NUCLEIC ACIDS USING THEM

Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property