FR2444681B1 - - Google Patents

Info

Publication number: FR2444681B1
Authority: FR; France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR7930829A

Other languages

Other versions

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-18

Filing date

1979-12-17

Publication date

1982-10-29

1979-12-17 Application filed by Sandoz AG filed Critical Sandoz AG

1980-07-18 Publication of FR2444681A1 publication Critical patent/FR2444681A1/en

1982-10-29 Application granted granted Critical

1982-10-29 Publication of FR2444681B1 publication Critical patent/FR2444681B1/fr

Status Granted legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

FR7930829A 1978-12-18 1979-12-17 NOVEL 1,4-DIHYDROPYRIDINES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS Granted FR2444681A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH1283578A CH639659A5 (en)	1978-12-18	1978-12-18	NEW 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE.

Publications (2)

Publication Number	Publication Date
FR2444681A1 FR2444681A1 (en)	1980-07-18
FR2444681B1 true FR2444681B1 (en)	1982-10-29

Family

ID=4386824

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7930829A Granted FR2444681A1 (en)	1978-12-18	1979-12-17	NOVEL 1,4-DIHYDROPYRIDINES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS

Country Status (18)

Country	Link
JP (1)	JPS5583783A (en)
AU (1)	AU536055B2 (en)
BE (1)	BE880591A (en)
CH (1)	CH639659A5 (en)
CY (1)	CY1321A (en)
DE (1)	DE2949491A1 (en)
FR (1)	FR2444681A1 (en)
GB (2)	GB2103203B (en)
HK (1)	HK16086A (en)
IE (1)	IE49496B1 (en)
IT (1)	IT1164097B (en)
KE (1)	KE3593A (en)
MY (1)	MY8500130A (en)
NL (2)	NL193066C (en)
NZ (1)	NZ192422A (en)
SE (1)	SE445219B (en)
SG (1)	SG97585G (en)
ZA (1)	ZA796842B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3022030A1 (en) *	1980-06-12	1981-12-17	Bayer Ag, 5090 Leverkusen	4-THIAZOLE or 4-IMIDAZOLE-SUBSTITUTED, 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM
CH655658B (en) *	1980-09-18	1986-05-15
DE3269219D1 (en) *	1981-11-17	1986-03-27	Fisons Plc	Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
ZA83959B (en) *	1982-03-10	1984-09-26	Sandoz Ltd	1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
US4414213A (en) *	1982-03-22	1983-11-08	Mead Johnson & Company	Dihydropyridyl cyclic imidate esters and their pharmaceutical use
IL68975A (en) *	1982-06-15	1987-01-30	Sandoz Ag	4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives in optically active form,their preparation and pharmaceutical compositions containing them
FR2528431B1 (en) *	1982-06-15	1986-01-10	Sandoz Sa	NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
JPS5978186A (en) *	1982-10-27	1984-05-04	Yoshitomi Pharmaceut Ind Ltd	1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative
US4794111A (en) *	1984-05-23	1988-12-27	Bayer Aktiengesellschaft	Dihydropyridine preparations containing β-blockers
NL194389C (en) *	1984-06-14	2002-03-04	Novartis Ag	Process for preparing a solid dispersion of a pharmaceutically active agent that has low water solubility in a solid matrix of a water-soluble polyalkylene glycol as a carrier.
US5260321A (en) *	1984-11-12	1993-11-09	Sandoz Ltd.	Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
HU197201B (en) *	1985-10-01	1989-03-28	Sandoz Ag	Process for producing oral pharmaceutical compositions of controlled solubility of the active components
DE3542794A1 (en) *	1985-12-04	1987-06-11	Bayer Ag	ANTI-HYPERTENSIVE COMBINATION PREPARATION
GB8626217D0 (en) *	1986-11-03	1986-12-03	Sandoz Ltd	Pharmaceutical compositions
US4816263A (en) *	1987-10-02	1989-03-28	Alza Corporation	Dosage form for treating cardiovascular diseases comprising isradipine
KR940003492B1 (en) *	1988-10-27	1994-04-23	주식회사 유한양행	1,4-dihydropyridine derivative and preparation method thereof
DE4222770A1 (en) *	1992-07-10	1994-01-13	Bayer Ag	Light-activated 1- (2-nitrobenzyl) -substituted 1,4-dihydropyridines
CN1649614A (en)	2002-02-22	2005-08-03	新河药品股份有限公司	Active agent delivery systems and methods for protecting and administering active agents
WO2005023787A1 (en) *	2003-09-10	2005-03-17	Shasun Chemicals And Drugs Limited	Process for the manufacture of 2,1,3-benzoxadiazole-4-carboxaldehyde
CN103613584B (en) *	2013-11-27	2016-04-27	沈阳药科大学	The method of a kind of Isrodipine synthetic product aftertreatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670824C3 (en) *	1967-03-20	1978-08-03	Bayer Ag, 5090 Leverkusen	1,4-Dihydropyridine-33-dicarboxylic acid alkyl ester
FR2320750A1 (en) *	1975-08-12	1977-03-11	Hexachimie	1,4-DIHYDRO PYRIDINES AND THEIR THERAPEUTIC APPLICATION
DE2616991A1 (en) *	1976-04-17	1977-10-27	Bayer Ag	Thio-substd. dihydro-pyridine derivs. - coronary vasodilators and antihypertensives prepd. e.g. by reacting dicarbonyl cpds. with amines and thio-substd. ketones
JPS5373327A (en) *	1976-12-13	1978-06-29	Matsushita Electric Ind Co Ltd	Power source system
DK149855C (en) *	1977-06-20	1987-04-21	Sandoz Ag	METHOD OF ANALOGY FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE DERIVATIVES

1978
- 1978-12-18 CH CH1283578A patent/CH639659A5/en not_active IP Right Cessation
1979
- 1979-12-08 DE DE19792949491 patent/DE2949491A1/en active Granted
- 1979-12-11 SE SE7910188A patent/SE445219B/en not_active IP Right Cessation
- 1979-12-13 BE BE1/9643A patent/BE880591A/en not_active IP Right Cessation
- 1979-12-14 GB GB08215988A patent/GB2103203B/en not_active Expired
- 1979-12-14 IT IT51095/79A patent/IT1164097B/en active Protection Beyond IP Right Term
- 1979-12-14 GB GB7943113A patent/GB2037766B/en not_active Expired
- 1979-12-14 NL NL7909024A patent/NL193066C/en not_active IP Right Cessation
- 1979-12-14 CY CY1321A patent/CY1321A/en unknown
- 1979-12-17 FR FR7930829A patent/FR2444681A1/en active Granted
- 1979-12-17 AU AU53896/79A patent/AU536055B2/en not_active Expired
- 1979-12-17 NZ NZ192422A patent/NZ192422A/en unknown
- 1979-12-17 JP JP16396579A patent/JPS5583783A/en active Granted
- 1979-12-17 IE IE2445/79A patent/IE49496B1/en not_active IP Right Cessation
- 1979-12-18 ZA ZA00796842A patent/ZA796842B/en unknown
1985
- 1985-12-20 SG SG975/85A patent/SG97585G/en unknown
- 1985-12-30 MY MY130/85A patent/MY8500130A/en unknown
1986
- 1986-01-08 KE KE3593A patent/KE3593A/en unknown
- 1986-03-06 HK HK160/86A patent/HK16086A/en not_active IP Right Cessation
1999
- 1999-05-11 NL NL990014C patent/NL990014I1/en unknown

Also Published As

Publication number	Publication date
NL193066B (en)	1998-05-06
AU536055B2 (en)	1984-04-19
MY8500130A (en)	1985-12-31
BE880591A (en)	1980-06-13
NZ192422A (en)	1982-09-14
IE792445L (en)	1980-06-18
GB2103203A (en)	1983-02-16
NL7909024A (en)	1980-06-20
SE445219B (en)	1986-06-09
DE2949491C2 (en)	1988-10-27
GB2037766B (en)	1983-02-16
IT7951095A0 (en)	1979-12-14
SG97585G (en)	1986-07-18
AU5389679A (en)	1980-06-26
IE49496B1 (en)	1985-10-16
NL990014I1 (en)	1999-07-01
FR2444681A1 (en)	1980-07-18
GB2037766A (en)	1980-07-16
SE7910188L (en)	1980-06-19
JPS5583783A (en)	1980-06-24
IT1164097B (en)	1987-04-08
KE3593A (en)	1986-02-07
HK16086A (en)	1986-03-14
NL193066C (en)	1998-09-08
JPH0369910B2 (en)	1991-11-05
CH639659A5 (en)	1983-11-30
CY1321A (en)	1986-06-27
DE2949491A1 (en)	1980-06-26
ZA796842B (en)	1981-07-29
GB2103203B (en)	1983-06-08

Publication	Publication Date	Title
FR2414952B1 (en)	1983-01-14
FR2415298B3 (en)	1981-02-13
FR2415885B1 (en)	1981-06-12
FR2414146B1 (en)	1984-10-19
FR2416109B1 (en)	1984-07-06
FR2414801B1 (en)	1981-11-27
FR2415801B2 (en)	1980-08-29
FR2416083B1 (en)	1982-12-17
FR2413071B3 (en)	1981-10-16
FR2395309B1 (en)	1982-10-29
FR2415357B3 (en)	1980-09-19
BG25974A1 (en)	1979-01-12
BG25955A1 (en)	1979-01-12
BG25806A1 (en)	1979-01-12
BG26337A2 (en)	1979-03-15
BG26022A1 (en)	1979-02-15
BG26017A1 (en)	1979-02-15
BG26015A1 (en)	1979-02-15
BG26014A1 (en)	1979-02-15
BG26013A1 (en)	1979-02-15
BG26012A1 (en)	1979-02-15
BG26009A1 (en)	1979-02-15
BG26008A1 (en)	1979-02-15
BG26007A1 (en)	1979-02-15
BG26006A1 (en)	1979-02-15

Legal Events

Date	Code	Title	Description
1992-08-14	CC	Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)	Free format text: 92C0169, 920507
1992-10-23	CB	Supplementary protection certificate (spc) granted (law of 25 june 1990)	Free format text: 92C0169, 791217
1993-04-23	CL	Concession to grant licences
1997-11-14	TP	Transmission of property