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FR2528431B1 - NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS - Google Patents

NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

Info

Publication number
FR2528431B1
FR2528431B1 FR8309551A FR8309551A FR2528431B1 FR 2528431 B1 FR2528431 B1 FR 2528431B1 FR 8309551 A FR8309551 A FR 8309551A FR 8309551 A FR8309551 A FR 8309551A FR 2528431 B1 FR2528431 B1 FR 2528431B1
Authority
FR
France
Prior art keywords
medicaments
novel
preparation
dihydropyridine derivatives
dihydropyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8309551A
Other languages
French (fr)
Other versions
FR2528431A1 (en
Inventor
Arnold Vogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2528431A1 publication Critical patent/FR2528431A1/en
Application granted granted Critical
Publication of FR2528431B1 publication Critical patent/FR2528431B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FR8309551A 1982-06-15 1983-06-07 NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS Expired FR2528431B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH369282 1982-06-15
CH369382 1982-06-15

Publications (2)

Publication Number Publication Date
FR2528431A1 FR2528431A1 (en) 1983-12-16
FR2528431B1 true FR2528431B1 (en) 1986-01-10

Family

ID=25693638

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8309551A Expired FR2528431B1 (en) 1982-06-15 1983-06-07 NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

Country Status (19)

Country Link
AU (1) AU1575383A (en)
BE (1) BE897000A (en)
CA (1) CA1208639A (en)
CH (1) CH660593A5 (en)
DE (1) DE3320616A1 (en)
DK (1) DK271183A (en)
ES (2) ES523243A0 (en)
FI (1) FI832072A7 (en)
FR (1) FR2528431B1 (en)
GB (1) GB2122192B (en)
HU (1) HU191853B (en)
IT (1) IT1178353B (en)
NL (1) NL8302067A (en)
NZ (1) NZ204536A (en)
PH (1) PH23436A (en)
PT (1) PT76870B (en)
SE (1) SE8303385L (en)
WO (1) WO1984000033A1 (en)
ZA (1) ZA834409B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431152A1 (en) * 1984-08-24 1986-03-06 Cassella Ag, 6000 Frankfurt METHOD FOR PRODUCING OPTICALLY ACTIVE, SUBSTITUTED 1,4-DIHYDROPYRIDINE AND THEIR USE AS A MEDICINAL PRODUCT
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
DE3447169A1 (en) * 1984-12-22 1986-07-03 Bayer Ag, 5090 Leverkusen OPTICALLY ACTIVE NITRODIHYDROPYRIDINE, METHOD FOR THE PRODUCTION AND THEIR USE IN MEDICINAL PRODUCTS
US4920225A (en) * 1986-12-22 1990-04-24 Laboratoires Syntex S.A. Resolution of 1,4-dihydropyridine derivatives
EP0287828A1 (en) * 1987-03-27 1988-10-26 Byk Gulden Lomberg Chemische Fabrik GmbH Intermediates and their preparation
DE4041814A1 (en) * 1990-12-24 1992-07-02 Byk Gulden Lomberg Chem Fab METHOD FOR PRODUCING DIHYDROPHYRIDINE CARBONIC ACIDS
US5135936A (en) * 1991-03-05 1992-08-04 Marion Merrell Dow Inc. Isomers of 1-azabicyclo[2.2.2]oct-3-yl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinediacarboxylic and their use as calcium antagonists
CN100425599C (en) * 2005-12-31 2008-10-15 清华大学 Organic electroluminescent material and its application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH639659A5 (en) * 1978-12-18 1983-11-30 Sandoz Ag NEW 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE.
DK149855C (en) * 1977-06-20 1987-04-21 Sandoz Ag METHOD OF ANALOGY FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE DERIVATIVES
DE2949464A1 (en) * 1978-12-18 1980-06-26 Sandoz Ag BENZOXADIAZOLES AND BENZOTHIADIAZOLES, THEIR PRODUCTION AND USE
FI813460L (en) * 1980-11-10 1982-05-11 Sandoz Ag NYA 4- (2,1,3-BENZOXADIAZOL-4-YL) -1,4-DIHYDRO-PYRIDIN DERIVATIVES DERAS FRAMSTAELLNINGSFOERFARANDE OCH DESSA INNEHAOLLANDE PHARMACEUTICAL COMPOSITION

Also Published As

Publication number Publication date
ES538157A0 (en) 1986-02-01
NL8302067A (en) 1984-01-02
FI832072L (en) 1983-12-16
FI832072A0 (en) 1983-06-08
FR2528431A1 (en) 1983-12-16
DK271183A (en) 1983-12-16
FI832072A7 (en) 1983-12-16
IT1178353B (en) 1987-09-09
AU1575383A (en) 1983-12-22
SE8303385L (en) 1983-12-16
CH660593A5 (en) 1987-05-15
PT76870B (en) 1986-02-27
GB2122192B (en) 1985-12-18
CA1208639A (en) 1986-07-29
ES8504179A1 (en) 1985-04-01
WO1984000033A1 (en) 1984-01-05
GB8316054D0 (en) 1983-07-20
NZ204536A (en) 1986-09-10
BE897000A (en) 1983-12-09
PT76870A (en) 1983-07-01
ES523243A0 (en) 1985-04-01
PH23436A (en) 1989-08-07
HU191853B (en) 1987-04-28
DE3320616A1 (en) 1983-12-15
ES8604578A1 (en) 1986-02-01
GB2122192A (en) 1984-01-11
ZA834409B (en) 1985-02-27
IT8348488A0 (en) 1983-06-13
DK271183D0 (en) 1983-06-13
SE8303385D0 (en) 1983-06-14

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Legal Events

Date Code Title Description
ST Notification of lapse