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FR2419265A1 - Procede de preparation d'un acide gras marque destine a servir de produit radiopharmaceutique - Google Patents

Procede de preparation d'un acide gras marque destine a servir de produit radiopharmaceutique

Info

Publication number
FR2419265A1
FR2419265A1 FR7905992A FR7905992A FR2419265A1 FR 2419265 A1 FR2419265 A1 FR 2419265A1 FR 7905992 A FR7905992 A FR 7905992A FR 7905992 A FR7905992 A FR 7905992A FR 2419265 A1 FR2419265 A1 FR 2419265A1
Authority
FR
France
Prior art keywords
fatty acid
mixture
preparation
labeled
radiopharmaceutical product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7905992A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forschungszentrum Juelich GmbH
Original Assignee
Kernforschungsanlage Juelich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kernforschungsanlage Juelich GmbH filed Critical Kernforschungsanlage Juelich GmbH
Publication of FR2419265A1 publication Critical patent/FR2419265A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
    • C07C53/19—Acids containing three or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

a. Procédé de préparation d'un acide gras marqué destiné à servir de produit radiopharmaceutique. b. Le procédé consiste à envoyer un mélange comprenant l'acide gras inaltéré, l'acide gras marqué par l'iode 123 en position oméga, une cétone et un iodure, en vue de séparer cbromatographiquement l'acide gras marqué par l'iode 123 en position oméga des autres constituants du mélange, sur une colonne de séparation garnie d'une substance de garnissage ayant une granulométrie déterminée comprise entre 5 et 30 mu , le mélange étant entraîné par un véhicule liquide envoyé sous pression dans la colonne de séparation c. Utilisation en médecine.
FR7905992A 1978-03-11 1979-03-08 Procede de preparation d'un acide gras marque destine a servir de produit radiopharmaceutique Withdrawn FR2419265A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2810696A DE2810696C3 (de) 1978-03-11 1978-03-11 Verfahren zur Gewinnung von ω-↑123↑J-Hexadecansäure oder ω↑123↑J-Heptadecansäure und deren Verwendung als Radiopharmaka

Publications (1)

Publication Number Publication Date
FR2419265A1 true FR2419265A1 (fr) 1979-10-05

Family

ID=6034214

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7905992A Withdrawn FR2419265A1 (fr) 1978-03-11 1979-03-08 Procede de preparation d'un acide gras marque destine a servir de produit radiopharmaceutique

Country Status (5)

Country Link
DE (1) DE2810696C3 (fr)
FR (1) FR2419265A1 (fr)
GB (1) GB2016455A (fr)
NL (1) NL7901820A (fr)
SE (1) SE7901916L (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508902A1 (fr) * 1981-07-02 1983-01-07 Commissariat Energie Atomique Procede de preparation extemporanee d'un acide gras injectable, marque a l'iode radioactif et preparation de derives iodes utilisables pour la mise en oeuvre de ce procede

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1236483A (fr) * 1984-03-19 1988-05-10 Commonwealth Of Australia (The) Marquage des molecules organiques

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EXBK/76 *
EXBK/77 *
EXBK/78 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508902A1 (fr) * 1981-07-02 1983-01-07 Commissariat Energie Atomique Procede de preparation extemporanee d'un acide gras injectable, marque a l'iode radioactif et preparation de derives iodes utilisables pour la mise en oeuvre de ce procede
EP0069648A1 (fr) * 1981-07-02 1983-01-12 Commissariat à l'Energie Atomique Procédé de préparation extemporanée d'un acide gras injectable, marqué à l'iode radioactif et préparation de dérivés iodes utilisables pour la mise en oeuvre de ce procédé
US4476106A (en) * 1981-07-02 1984-10-09 Commissariat A L'energie Atomique Process for the extemporaneous preparation of an injectable fatty acid tagged in the omega position by means of radioactive iodine

Also Published As

Publication number Publication date
NL7901820A (nl) 1979-09-13
GB2016455A (en) 1979-09-26
DE2810696C3 (de) 1982-02-25
DE2810696A1 (de) 1979-09-13
DE2810696B2 (de) 1981-01-08
SE7901916L (sv) 1979-09-12

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Legal Events

Date Code Title Description
ST Notification of lapse