FR12C0064I2 - Compositions pharmaceutiques injectables d'un derive d'anthracenedione avec action anti-tumorale - Google Patents
Compositions pharmaceutiques injectables d'un derive d'anthracenedione avec action anti-tumoraleInfo
- Publication number
- FR12C0064I2 FR12C0064I2 FR12C0064C FR12C0064C FR12C0064I2 FR 12C0064 I2 FR12C0064 I2 FR 12C0064I2 FR 12C0064 C FR12C0064 C FR 12C0064C FR 12C0064 C FR12C0064 C FR 12C0064C FR 12C0064 I2 FR12C0064 I2 FR 12C0064I2
- Authority
- FR
- France
- Prior art keywords
- pharmaceutical compositions
- injectable pharmaceutical
- antitumor action
- anthracenedione derivative
- anthracenedione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- RGHILYZRVFRRNK-UHFFFAOYSA-N anthracene-1,2-dione Chemical class C1=CC=C2C=C(C(C(=O)C=C3)=O)C3=CC2=C1 RGHILYZRVFRRNK-UHFFFAOYSA-N 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 title 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- SVAGFBGXEWPNJC-SPIKMXEPSA-N 6,9-bis(2-aminoethylamino)benzo[g]isoquinoline-5,10-dione;(z)-but-2-enedioic acid Chemical compound OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.O=C1C2=CN=CC=C2C(=O)C2=C1C(NCCN)=CC=C2NCCN SVAGFBGXEWPNJC-SPIKMXEPSA-N 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI001040A ITMI20021040A1 (it) | 2002-05-16 | 2002-05-16 | Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale |
| PCT/EP2003/004871 WO2003097101A1 (en) | 2002-05-16 | 2003-05-09 | Injectable pharmaceutical compositions of an anthracenedione derivative with anti-tumoral activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR12C0064I1 FR12C0064I1 (ja) | 2012-12-14 |
| FR12C0064I2 true FR12C0064I2 (fr) | 2013-08-16 |
Family
ID=11449903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR12C0064C Active FR12C0064I2 (fr) | 2002-05-16 | 2012-10-25 | Compositions pharmaceutiques injectables d'un derive d'anthracenedione avec action anti-tumorale |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20060199831A1 (ja) |
| EP (1) | EP1503797B1 (ja) |
| JP (1) | JP4624780B2 (ja) |
| AT (1) | ATE381944T1 (ja) |
| AU (1) | AU2003240613A1 (ja) |
| CA (1) | CA2486001C (ja) |
| DE (1) | DE60318310T2 (ja) |
| ES (1) | ES2298521T3 (ja) |
| FR (1) | FR12C0064I2 (ja) |
| IT (1) | ITMI20021040A1 (ja) |
| MX (1) | MXPA04011348A (ja) |
| WO (1) | WO2003097101A1 (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2106788A1 (en) * | 2008-04-04 | 2009-10-07 | Ipsen Pharma | Liquid and freeze dried formulations |
| CN108186560A (zh) * | 2016-03-26 | 2018-06-22 | 夏建明 | 一种治疗非霍奇金淋巴瘤的注射液及其制备方法 |
| CN108113967A (zh) * | 2016-03-26 | 2018-06-05 | 夏建明 | 一种治疗非霍奇金淋巴瘤的冻干组合物及其制备方法 |
| CN105997896B (zh) * | 2016-05-28 | 2019-07-05 | 长沙秋点兵信息科技有限公司 | 治疗非霍奇金淋巴瘤的注射用冻干粉及其制备方法 |
| CN106176630B (zh) * | 2016-08-03 | 2019-01-04 | 湖北丽益医药科技有限公司 | 一种注射用马来酸匹杉琼无菌粉末的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3590124A (en) * | 1967-06-27 | 1971-06-29 | Us Navy | Blood transfusion fluids having reduced turbulent friction properties |
| JP2690009B2 (ja) * | 1986-07-10 | 1997-12-10 | エーザイ 株式会社 | セフアロスポリン注射剤 |
| NZ241868A (en) | 1991-03-08 | 1995-05-26 | Univ Vermont | 6,9-bis(substituted-amino)benzo[g]isoquinoline-5,10-diones, preparation and pharmaceutical compositions thereof |
| JP3501471B2 (ja) * | 1992-06-15 | 2004-03-02 | 旭化成ファーマ株式会社 | カルシトニン類の安定化組成物および安定化法 |
| JPH08126685A (ja) * | 1994-01-26 | 1996-05-21 | Shionogi & Co Ltd | デキストラン類の凍結乾燥方法 |
| US5587382A (en) * | 1994-03-28 | 1996-12-24 | Boehringer Mannheim Italia, Spa | 6,9-bis[(2-aminoethyl) amino]benzo [g]isoquinoline-5,10- dione dimaleate; an aza-anthracenedione with reduced cardiotoxicity |
| WO1999024401A1 (en) * | 1997-11-10 | 1999-05-20 | G.D. Searle & Co. | Use of alkylated iminosugars to treat multidrug resistance |
| GB9808922D0 (en) * | 1998-04-24 | 1998-06-24 | Cantab Pharmaceuticals Res Ltd | Virus preparations |
| TWI233805B (en) * | 1999-07-01 | 2005-06-11 | Fujisawa Pharmaceutical Co | Stabilized pharmaceutical composition in lyophilized form as antifungal agent |
| IT1315253B1 (it) * | 1999-10-22 | 2003-02-03 | Novuspharma Spa | Preparazione liposomiale di 6,9-bis-(2-amminoetil)ammino|benzog|isochinolin-5,10-dione dimaleato |
-
2002
- 2002-05-16 IT IT2002MI001040A patent/ITMI20021040A1/it unknown
-
2003
- 2003-05-09 ES ES03729997T patent/ES2298521T3/es not_active Expired - Lifetime
- 2003-05-09 JP JP2004505097A patent/JP4624780B2/ja not_active Expired - Lifetime
- 2003-05-09 US US10/514,301 patent/US20060199831A1/en not_active Abandoned
- 2003-05-09 AT AT03729997T patent/ATE381944T1/de not_active IP Right Cessation
- 2003-05-09 DE DE60318310T patent/DE60318310T2/de not_active Expired - Lifetime
- 2003-05-09 MX MXPA04011348A patent/MXPA04011348A/es active IP Right Grant
- 2003-05-09 AU AU2003240613A patent/AU2003240613A1/en not_active Abandoned
- 2003-05-09 CA CA2486001A patent/CA2486001C/en not_active Expired - Lifetime
- 2003-05-09 EP EP03729997A patent/EP1503797B1/en not_active Expired - Lifetime
- 2003-05-09 WO PCT/EP2003/004871 patent/WO2003097101A1/en active IP Right Grant
-
2010
- 2010-12-10 US US12/964,861 patent/US9211262B2/en not_active Expired - Lifetime
-
2012
- 2012-10-25 FR FR12C0064C patent/FR12C0064I2/fr active Active
-
2015
- 2015-11-10 US US14/937,689 patent/US20160256557A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI20021040A0 (it) | 2002-05-16 |
| CA2486001C (en) | 2010-04-13 |
| US9211262B2 (en) | 2015-12-15 |
| DE60318310T2 (de) | 2008-12-11 |
| AU2003240613A1 (en) | 2003-12-02 |
| US20160256557A1 (en) | 2016-09-08 |
| ATE381944T1 (de) | 2008-01-15 |
| US20060199831A1 (en) | 2006-09-07 |
| JP4624780B2 (ja) | 2011-02-02 |
| ITMI20021040A1 (it) | 2003-11-17 |
| CA2486001A1 (en) | 2003-11-27 |
| ES2298521T3 (es) | 2008-05-16 |
| EP1503797A1 (en) | 2005-02-09 |
| FR12C0064I1 (ja) | 2012-12-14 |
| US20110144147A1 (en) | 2011-06-16 |
| WO2003097101A1 (en) | 2003-11-27 |
| JP2005530792A (ja) | 2005-10-13 |
| MXPA04011348A (es) | 2005-08-15 |
| EP1503797B1 (en) | 2007-12-26 |
| DE60318310D1 (de) | 2008-02-07 |
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