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FI964783L - Method for treating cancer by regulating p53 protein - Google Patents

Method for treating cancer by regulating p53 protein Download PDF

Info

Publication number
FI964783L
FI964783L FI964783A FI964783A FI964783L FI 964783 L FI964783 L FI 964783L FI 964783 A FI964783 A FI 964783A FI 964783 A FI964783 A FI 964783A FI 964783 L FI964783 L FI 964783L
Authority
FI
Finland
Prior art keywords
protein
regulating
treating cancer
cancer
treating
Prior art date
Application number
FI964783A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI120501B (en
FI964783A0 (en
Inventor
Jean-Marie Blanchard
Serge Carillo
Marc Peichaczyk
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI964783A0 publication Critical patent/FI964783A0/en
Publication of FI964783L publication Critical patent/FI964783L/en
Application granted granted Critical
Publication of FI120501B publication Critical patent/FI120501B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI964783A 1994-05-31 1996-11-29 Use of inhibitors of calpain activity, which regulate the level of p53 protein in the manufacture of anti-cancer drugs FI120501B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9406583 1994-05-31
FR9406583A FR2720277B1 (en) 1994-05-31 1994-05-31 Method of treating cancer by regulating the P53 protein.
FR9500670 1995-05-22
PCT/FR1995/000670 WO1995033060A1 (en) 1994-05-31 1995-05-22 Method of cancer treatment by p53 protein control

Publications (3)

Publication Number Publication Date
FI964783A0 FI964783A0 (en) 1996-11-29
FI964783L true FI964783L (en) 1996-11-29
FI120501B FI120501B (en) 2009-11-13

Family

ID=9463670

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964783A FI120501B (en) 1994-05-31 1996-11-29 Use of inhibitors of calpain activity, which regulate the level of p53 protein in the manufacture of anti-cancer drugs

Country Status (8)

Country Link
EP (1) EP0763121A1 (en)
JP (1) JPH10500978A (en)
AU (1) AU714209B2 (en)
CA (1) CA2190293C (en)
FI (1) FI120501B (en)
FR (1) FR2720277B1 (en)
NO (1) NO321411B1 (en)
WO (1) WO1995033060A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19518488C1 (en) * 1995-05-19 1996-10-10 Progen Biotechnik Gmbh Autoantigen, suitable for determining a tendency to thrombosis
EP0799892A3 (en) * 1996-04-05 1998-08-12 Takeda Chemical Industries, Ltd. Calpain, its production and use
US6232454B1 (en) 1998-02-27 2001-05-15 Incyte Genomics, Inc. Human proteinase molecules
AU2344100A (en) * 1998-11-18 2000-06-05 Canji, Inc. Viral vectors with late transgene expression
AU2001247922A1 (en) * 2000-03-31 2001-10-15 Parker Hughes Institute Calpain inhibitors in cancer treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753665B2 (en) * 1984-04-20 1995-06-07 財団法人癌研究会 Anti-metastatic agent
US5340922B1 (en) * 1988-05-31 1999-11-02 Mclean Hospital Corp Neural calcium-activated neutral proteinase inhibitors
EP0395309B1 (en) * 1989-04-28 1995-12-27 Takara Shuzo Co. Ltd. Human calpastatin-like polypeptide
JPH0641067A (en) * 1992-04-20 1994-02-15 Kitasato Inst:The New calpain-inhibitor kp-1241 and its production
EP0580161A1 (en) * 1992-07-22 1994-01-26 THE McLEAN HOSPITAL CORPORATION Prophylactic and therapeutic treatment of Alzheimer's disease
US5607831A (en) * 1993-03-25 1997-03-04 The United States Of America As Represented By The Department Of Health And Human Services In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death

Also Published As

Publication number Publication date
FI120501B (en) 2009-11-13
FI964783A0 (en) 1996-11-29
FR2720277A1 (en) 1995-12-01
EP0763121A1 (en) 1997-03-19
CA2190293C (en) 2011-06-28
AU714209B2 (en) 1999-12-23
WO1995033060A1 (en) 1995-12-07
CA2190293A1 (en) 1995-12-07
NO321411B1 (en) 2006-05-08
JPH10500978A (en) 1998-01-27
FR2720277B1 (en) 1996-07-12
NO964772L (en) 1996-11-11
NO964772D0 (en) 1996-11-11
AU2620695A (en) 1995-12-21

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Owner name: AVENTIS PHARMA S.A.

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