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FI964410L - Förfarande för framställning av 4-amino-delta4-3-ketosteroider genom 4-nitro-delta4-3-ketosteroider - Google Patents

Förfarande för framställning av 4-amino-delta4-3-ketosteroider genom 4-nitro-delta4-3-ketosteroider Download PDF

Info

Publication number
FI964410L
FI964410L FI964410A FI964410A FI964410L FI 964410 L FI964410 L FI 964410L FI 964410 A FI964410 A FI 964410A FI 964410 A FI964410 A FI 964410A FI 964410 L FI964410 L FI 964410L
Authority
FI
Finland
Prior art keywords
delta4
ketosteroids
nitro
amino
preparing
Prior art date
Application number
FI964410A
Other languages
English (en)
Finnish (fi)
Other versions
FI964410A0 (sv
Inventor
Philip Marvin Weintraub
Cynthia Ann Gates
Michael Richard Angelastro
Timothy Thomas Curran
Gary Alan Flynn
Chi-Hsin Richard King
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of FI964410L publication Critical patent/FI964410L/sv
Publication of FI964410A0 publication Critical patent/FI964410A0/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011Unsubstituted amino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI964410A 1994-05-02 1996-11-01 Förfarande för framställning av 4-amino-delta4-3-ketosteroider genom 4-nitro-delta4-3-ketosteroider FI964410A0 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23143394A 1994-05-02 1994-05-02
PCT/US1995/004399 WO1995029932A1 (en) 1994-05-02 1995-04-11 Process for the preparation of 4-amino-δ4-3-ketosteroids via 4-nitro-δ4-3-ketosteroids

Publications (2)

Publication Number Publication Date
FI964410L true FI964410L (sv) 1996-11-01
FI964410A0 FI964410A0 (sv) 1996-11-01

Family

ID=22869232

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964410A FI964410A0 (sv) 1994-05-02 1996-11-01 Förfarande för framställning av 4-amino-delta4-3-ketosteroider genom 4-nitro-delta4-3-ketosteroider

Country Status (18)

Country Link
US (4) US5750744A (sv)
EP (1) EP0758340B1 (sv)
JP (1) JPH09512547A (sv)
CN (1) CN1042540C (sv)
AT (1) ATE175419T1 (sv)
AU (1) AU686793B2 (sv)
CA (1) CA2188760A1 (sv)
DE (1) DE69507139T2 (sv)
DK (1) DK0758340T3 (sv)
ES (1) ES2128052T3 (sv)
FI (1) FI964410A0 (sv)
GR (1) GR3029433T3 (sv)
HU (1) HUT75523A (sv)
IL (1) IL113532A (sv)
NO (1) NO964627L (sv)
NZ (1) NZ283974A (sv)
WO (1) WO1995029932A1 (sv)
ZA (1) ZA953357B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2347027T3 (es) 1998-05-22 2010-10-22 The Board Of Trustees Of The Leland Stanford Junior University Moleculas bifuncionales y terapias basadas en las mismas.
WO2003009815A2 (en) 2001-07-25 2003-02-06 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
WO2004037843A2 (en) * 2002-10-25 2004-05-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Crを含むタンパク質に対して特異的な受容体−結合タンパク質(rap)変異体を含む組成物およびその使用
NZ594310A (en) 2009-02-20 2014-02-28 To Bbb Holding B V Glutathione-based drug delivery system
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB892620A (en) * 1957-07-20 1962-03-28 Syntex Sa Cyclopentanophenanthrene derivatives
US3014632A (en) * 1961-03-06 1961-12-26 American Can Co Divider
US3159622A (en) * 1963-03-22 1964-12-01 Searle & Co 17 alpha-(2-carboxyethyl)-17 belta-hydroxy-6-nitroandrost-4-en-3-one gamma-lactones
GB8503940D0 (en) * 1985-02-15 1985-03-20 Erba Farmitalia 4-substituted androstendione derivatives
US5218110A (en) * 1990-08-01 1993-06-08 Merrell Dow Pharmaceuticals 4-amino-Δ4 -steroids and their use as 5α-reductase inhibitors
US5120840A (en) * 1990-08-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. 4-amino-4-ene-steroids and their use as 5α-reductase inhibitors
AU642757B2 (en) * 1990-08-01 1993-10-28 Merrell Dow Pharmaceuticals Inc. 4-amino-delta4, 6-steroids and their use as 5alpha-reductase inhibitors
US5143909A (en) * 1991-03-19 1992-09-01 Merrell Dow Pharmaceuticals Inc. Aminosteroids in a method for inhibiting c17-20 lyase

Also Published As

Publication number Publication date
EP0758340B1 (en) 1999-01-07
US5869475A (en) 1999-02-09
US5750744A (en) 1998-05-12
JPH09512547A (ja) 1997-12-16
CN1147258A (zh) 1997-04-09
DE69507139T2 (de) 1999-09-30
CA2188760A1 (en) 1995-11-09
US5990328A (en) 1999-11-23
EP0758340A1 (en) 1997-02-19
GR3029433T3 (en) 1999-05-28
ES2128052T3 (es) 1999-05-01
ATE175419T1 (de) 1999-01-15
NZ283974A (en) 1998-02-26
AU2244995A (en) 1995-11-29
HUT75523A (en) 1997-05-28
AU686793B2 (en) 1998-02-12
NO964627D0 (no) 1996-11-01
US5965550A (en) 1999-10-12
IL113532A (en) 2000-02-17
HU9603035D0 (en) 1997-01-28
CN1042540C (zh) 1999-03-17
FI964410A0 (sv) 1996-11-01
DE69507139D1 (de) 1999-02-18
WO1995029932A1 (en) 1995-11-09
IL113532A0 (en) 1995-07-31
DK0758340T3 (da) 1999-08-30
NO964627L (no) 1997-01-02
ZA953357B (en) 1996-01-17

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