FI961634A0 - Antitromboottisia atsasykloalkyylialkanoyyli peptidejä ja pseudopeptidejä - Google Patents

Antitromboottisia atsasykloalkyylialkanoyyli peptidejä ja pseudopeptidejä

Info

Publication number: FI961634A0
Authority: FI; Finland
Prior art keywords: pct; date; pseudopeptides; sec; prevention
Prior art date: 1993-10-15

Application number

FI961634A

Other languages

English (en)

Swedish (sv)

Other versions

FI961634A (fi

Inventor

Scott I Klein

Bruce F Molino

Original Assignee

Rhone Poulenc Rorer Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-15

Filing date

1996-04-12

Publication date

1996-04-12

1996-04-12 Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma

1996-04-12 Publication of FI961634A0 publication Critical patent/FI961634A0/fi

1996-05-23 Publication of FI961634A publication Critical patent/FI961634A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Crystallography & Structural Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI961634A 1993-10-15 1996-04-12 Antitromboottisia atsasykloalkyylialkanoyyli peptidejä ja pseudopeptidejä FI961634A (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US13882093A	1993-10-15	1993-10-15
PCT/US1994/012135 WO1995010295A1 (en)	1993-10-15	1994-10-17	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides

Publications (2)

Publication Number	Publication Date
FI961634A0 true FI961634A0 (fi)	1996-04-12
FI961634A FI961634A (fi)	1996-05-23

Family

ID=22483811

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI961634A FI961634A (fi)	1993-10-15	1996-04-12	Antitromboottisia atsasykloalkyylialkanoyyli peptidejä ja pseudopeptidejä

Country Status (28)

Country	Link
US (1)	US5866685A (fi)
EP (1)	EP0812205B1 (fi)
JP (1)	JP3032297B2 (fi)
KR (1)	KR100304332B1 (fi)
CN (1)	CN1135717A (fi)
AT (1)	ATE199727T1 (fi)
AU (1)	AU703854B2 (fi)
BG (1)	BG63166B1 (fi)
BR (1)	BR9407839A (fi)
CA (1)	CA2174097C (fi)
CZ (1)	CZ291378B6 (fi)
DE (1)	DE69426897T2 (fi)
DK (1)	DK0812205T3 (fi)
ES (1)	ES2155122T3 (fi)
FI (1)	FI961634A (fi)
GR (1)	GR3035581T3 (fi)
HK (1)	HK1006225A1 (fi)
HU (1)	HU222248B1 (fi)
NO (1)	NO961460L (fi)
NZ (1)	NZ275948A (fi)
PL (1)	PL181749B1 (fi)
PT (1)	PT812205E (fi)
RO (1)	RO115520B1 (fi)
RU (1)	RU2134695C1 (fi)
SG (1)	SG64919A1 (fi)
SK (1)	SK47796A3 (fi)
UA (1)	UA44258C2 (fi)
WO (1)	WO1995010295A1 (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5780590A (en) *	1993-10-15	1998-07-14	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
DK0812205T3 (da) *	1993-10-15	2001-04-17	Rhone Poulenc Rorer Pharma	Antithrombotiske azacycloalkylalkanoylpeptider og -pseudopeptider
US6274705B1 (en) *	1996-05-02	2001-08-14	Aventis Pharmaceuticals Products Inc.	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
BR9711340A (pt) *	1996-08-21	1999-08-17	Rhone Poulenc Rorer Pharma	Composto composi-Æo farmac-utica e processo para preparar um composto
CA2272317C (en) *	1996-11-27	2001-01-30	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Pharmaceutical composition comprising a compound having anti-xa activity and a platelet aggregation antagonist compound
WO1999019294A1 (en) *	1997-05-14	1999-04-22	Aventis Pharmaceuticals Products Inc. Legal/Patents	Process for the preparation of azacycloalkylalkanoyl pseudotetrapeptides
ZA989241B (en) *	1997-10-10	1999-06-04	Rhone Poulenc Rorer Pharma	Process for the preparation of azacycloalkylalkanoyl pseudotetrapeptides
AU2844800A (en) *	1998-12-30	2000-07-24	Aventis Pharmaceuticals Products Inc.	Process for preparing a stable non-hygroscopic crystalline n-(n-(n- piperdin- 4-yl)butanoyl)- n.ethylglycyl)- (l)-aspartyl) -ss-cyclohexylalanine amide
CN101735307B (zh) *	2008-11-18	2012-05-30	北京航空航天大学	一种血小板膜糖蛋白寡肽或其修饰物/衍生物以及它们的应用
RU2014153787A (ru) *	2012-06-11	2016-08-10	Дзе Кливленд Клиник Фаундейшн	Лечение и профилактика сердечно-сосудистого заболевания и тромбоза

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683291A (en) *	1985-10-28	1987-07-28	Scripps Clinic And Research Foundation	Platelet binding inhibitors
FR2608160B1 (fr) *	1986-12-15	1989-03-31	Inst Nat Sante Rech Med	Nouveaux derives peptidiques et leur application notamment en therapeutique
US4857508A (en) *	1987-12-03	1989-08-15	Monsanto Company	Novel platelet-aggregation inhibitor peptide derivatives
US4992463A (en) *	1988-07-20	1991-02-12	Monsanto Company	Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation
US5037808A (en) *	1988-07-20	1991-08-06	Monsanto Co.	Indolyl platelet-aggregation inhibitors
US4879313A (en) *	1988-07-20	1989-11-07	Mosanto Company	Novel platelet-aggregation inhibitors
US5023233A (en) *	1989-07-28	1991-06-11	Merck & Co., Inc.	Fibrinogen receptor antagonists
JPH05500954A (ja) *	1989-09-29	1993-02-25	ローヌ―プーラン　ローラー　インターナショナル（ホウルディングス）　インコーポレイテッド	抗血栓性ペプチド及び疑似ペプチド
US5051405A (en) *	1989-10-10	1991-09-24	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Anti-thrombotic peptides and pseudopeptides
US5064814A (en) *	1990-04-05	1991-11-12	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Anti-thrombotic peptide and pseudopeptide derivatives
IL99539A0 (en) *	1990-09-27	1992-08-18	Merck & Co Inc	Fibrinogen receptor antagonists and pharmaceutical compositions containing them
NZ239876A (en) *	1990-09-27	1993-12-23	Merck & Co Inc	Glycyl-b-alanine derivatives and pharmaceutical compositions thereof.
EP0584066A4 (en) *	1991-04-11	1994-10-12	Rhone Poulenc Rorer Int	Anti-thrombotic peptide and pseudopeptide derivatives.
DK0812205T3 (da) *	1993-10-15	2001-04-17	Rhone Poulenc Rorer Pharma	Antithrombotiske azacycloalkylalkanoylpeptider og -pseudopeptider

1994
- 1994-10-17 DK DK95900403T patent/DK0812205T3/da active
- 1994-10-17 CN CN94194242A patent/CN1135717A/zh active Pending
- 1994-10-17 RO RO96-00812A patent/RO115520B1/ro unknown
- 1994-10-17 AT AT95900403T patent/ATE199727T1/de not_active IP Right Cessation
- 1994-10-17 PL PL94313975A patent/PL181749B1/pl unknown
- 1994-10-17 UA UA96051845A patent/UA44258C2/uk unknown
- 1994-10-17 PT PT95900403T patent/PT812205E/pt unknown
- 1994-10-17 US US08/628,648 patent/US5866685A/en not_active Expired - Lifetime
- 1994-10-17 RU RU96109375/04A patent/RU2134695C1/ru not_active IP Right Cessation
- 1994-10-17 NZ NZ275948A patent/NZ275948A/en unknown
- 1994-10-17 CZ CZ19961084A patent/CZ291378B6/cs not_active IP Right Cessation
- 1994-10-17 HU HU9600983A patent/HU222248B1/hu not_active IP Right Cessation
- 1994-10-17 KR KR1019960701992A patent/KR100304332B1/ko not_active IP Right Cessation
- 1994-10-17 JP JP7512250A patent/JP3032297B2/ja not_active Expired - Fee Related
- 1994-10-17 SG SG1996008589A patent/SG64919A1/en unknown
- 1994-10-17 AU AU81237/94A patent/AU703854B2/en not_active Ceased
- 1994-10-17 SK SK477-96A patent/SK47796A3/sk unknown
- 1994-10-17 BR BR9407839A patent/BR9407839A/pt not_active Application Discontinuation
- 1994-10-17 DE DE69426897T patent/DE69426897T2/de not_active Expired - Lifetime
- 1994-10-17 ES ES95900403T patent/ES2155122T3/es not_active Expired - Lifetime
- 1994-10-17 WO PCT/US1994/012135 patent/WO1995010295A1/en active IP Right Grant
- 1994-10-17 EP EP95900403A patent/EP0812205B1/en not_active Expired - Lifetime
- 1994-10-17 CA CA002174097A patent/CA2174097C/en not_active Expired - Fee Related
1996
- 1996-04-12 NO NO961460A patent/NO961460L/no not_active Application Discontinuation
- 1996-04-12 FI FI961634A patent/FI961634A/fi unknown
- 1996-04-26 BG BG100544A patent/BG63166B1/bg unknown
1998
- 1998-06-16 HK HK98105458A patent/HK1006225A1/xx not_active IP Right Cessation
2001
- 2001-03-15 GR GR20010400194T patent/GR3035581T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69426897D1 (de)	2001-04-19
DE69426897T2 (de)	2001-07-05
EP0812205A1 (en)	1997-12-17
PL313975A1 (en)	1996-08-05
CA2174097C (en)	2002-06-04
UA44258C2 (uk)	2002-02-15
AU8123794A (en)	1995-05-04
US5866685A (en)	1999-02-02
CZ291378B6 (cs)	2003-02-12
GR3035581T3 (en)	2001-06-29
KR100304332B1 (ko)	2001-11-26
CZ108496A3 (en)	1996-12-11
SG64919A1 (en)	1999-05-25
CN1135717A (zh)	1996-11-13
NO961460D0 (no)	1996-04-12
JPH09507213A (ja)	1997-07-22
PT812205E (pt)	2001-08-30
HK1006225A1 (en)	1999-02-19
AU703854B2 (en)	1999-04-01
RO115520B1 (ro)	2000-03-30
CA2174097A1 (en)	1995-04-20
NZ275948A (en)	1997-02-24
EP0812205A4 (en)	1999-03-31
HUT73856A (en)	1996-09-30
BG63166B1 (bg)	2001-05-31
BG100544A (bg)	1996-11-29
DK0812205T3 (da)	2001-04-17
SK47796A3 (en)	1997-03-05
WO1995010295A1 (en)	1995-04-20
ATE199727T1 (de)	2001-03-15
EP0812205B1 (en)	2001-03-14
HU222248B1 (hu)	2003-05-28
JP3032297B2 (ja)	2000-04-10
RU2134695C1 (ru)	1999-08-20
ES2155122T3 (es)	2001-05-01
PL181749B1 (pl)	2001-09-28
HU9600983D0 (en)	1996-06-28
FI961634A (fi)	1996-05-23
NO961460L (no)	1996-06-17
BR9407839A (pt)	1997-05-13

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RU93054168A (ru)	1996-10-10	Димер молекулярного варианта аро-липопротеина, способ его получения, фармацевтическая композиция на его основе
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FI961634A0 (fi)	1996-04-12	Antitromboottisia atsasykloalkyylialkanoyyli peptidejä ja pseudopeptidejä
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FR2710844B1 (fr)	1995-12-29	Composition pour le traitement ou la prévention de l'herpès.
CA2179857A1 (en)	1996-12-29	Medicaments for the treatment or prophylaxis of ischemia-reperfusion injury
KR960000248A (ko)	1996-01-25	골대사 질환 치료제
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NO961357L (no)	1996-06-06	Nye terapeutisk aktive peptidforbindelser i blodkoagulasjonskaskaden, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem
MX9207343A (es)	1994-01-31	Derivados antitromboticos de acido diaminoalcanoico.
MX9601659A (es)	1997-07-31	Antagonistas del receptor de adhesion, procedimiento para prepararlos, composiciones farmaceuticas que los contienen y su empleo para preparar medicamentos y combatir enfermedades.
RU95104302A (ru)	1998-02-10	Аппликационный материал лечебно-профилактического назначения