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FI95704B - Förfarande för framställning av nya terapeutiskt användbara pyridinderivat - Google Patents

Förfarande för framställning av nya terapeutiskt användbara pyridinderivat

Info

Publication number
FI95704B
FI95704B FI900886A FI900886A FI95704B FI 95704 B FI95704 B FI 95704B FI 900886 A FI900886 A FI 900886A FI 900886 A FI900886 A FI 900886A FI 95704 B FI95704 B FI 95704B
Authority
FI
Finland
Prior art keywords
preparation
therapeutically useful
pyridine derivatives
novel therapeutically
useful pyridine
Prior art date
Application number
FI900886A
Other languages
English (en)
Finnish (fi)
Other versions
FI95704C (sv
FI900886A0 (sv
Inventor
Per Sauerberg
Preben H Olesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK82589A external-priority patent/DK82589A/da
Priority claimed from DK231589A external-priority patent/DK231589D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI900886A0 publication Critical patent/FI900886A0/sv
Publication of FI95704B publication Critical patent/FI95704B/sv
Application granted granted Critical
Publication of FI95704C publication Critical patent/FI95704C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI900886A 1989-02-22 1990-02-22 Förfarande för framställning av nya terapeutiskt användbara pyridinderivat FI95704C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK82589A DK82589A (da) 1989-02-22 1989-02-22 Piperidinforbindelser, deres fremstilling og anvendelse
DK82589 1989-02-22
DK231589 1989-05-12
DK231589A DK231589D0 (da) 1989-05-12 1989-05-12 Piperidinforbindelser og deres fremstilling og anvendelse

Publications (3)

Publication Number Publication Date
FI900886A0 FI900886A0 (sv) 1990-02-22
FI95704B true FI95704B (sv) 1995-11-30
FI95704C FI95704C (sv) 1996-03-11

Family

ID=26064725

Family Applications (2)

Application Number Title Priority Date Filing Date
FI900887A FI900887A0 (fi) 1989-02-22 1990-02-22 Piperidinfoereningar samt framstaellning och anvaendning av dessa.
FI900886A FI95704C (sv) 1989-02-22 1990-02-22 Förfarande för framställning av nya terapeutiskt användbara pyridinderivat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI900887A FI900887A0 (fi) 1989-02-22 1990-02-22 Piperidinfoereningar samt framstaellning och anvaendning av dessa.

Country Status (22)

Country Link
US (5) US5043345A (sv)
EP (2) EP0384285A3 (sv)
JP (2) JPH02255680A (sv)
KR (1) KR0163763B1 (sv)
CN (1) CN1028105C (sv)
AR (1) AR247565A1 (sv)
AT (1) ATE123030T1 (sv)
AU (2) AU629302B2 (sv)
CA (2) CA2010579A1 (sv)
DE (1) DE69019550T2 (sv)
DK (1) DK0384288T3 (sv)
ES (1) ES2072323T3 (sv)
FI (2) FI900887A0 (sv)
GR (1) GR3017062T3 (sv)
HU (2) HU221623B1 (sv)
IE (1) IE69672B1 (sv)
IL (2) IL93352A (sv)
NO (2) NO900831L (sv)
NZ (1) NZ232615A (sv)
PH (1) PH26465A (sv)
PT (2) PT93241B (sv)
RU (1) RU2042676C1 (sv)

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EP0459568A3 (en) * 1990-05-31 1992-09-30 Merck Sharp & Dohme Ltd. Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5418240A (en) * 1990-08-21 1995-05-23 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
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EP0561913B1 (en) * 1990-11-29 1998-04-01 Allergan, Inc. Use of pyridine derivatives in the treatment of ocular hypertension
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IE922270A1 (en) * 1991-07-26 1993-01-27 Akzo Nv Pyrazole derivatives
US5641791A (en) * 1991-08-13 1997-06-24 Novo Nordisk A.S Heterocyclic compounds and their preparation and use
US5175166A (en) * 1991-08-27 1992-12-29 The University Of Toledo Muscarinic agonists
WO1993014089A1 (en) * 1992-01-13 1993-07-22 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5244906A (en) * 1992-01-23 1993-09-14 Dowelanco Insect control with substituted oxadiazole and thiadiazole compounds
CA2146019A1 (en) * 1992-10-23 1994-05-11 Howard B. Broughton Dopamine receptor subtype ligands
DE69426021T2 (de) * 1993-06-04 2001-05-17 Novo Nordisk A/S, Bagsvaerd Xamonelin-Tartrat
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US5753683A (en) * 1993-08-19 1998-05-19 Novo Nordisk A/S Antipsychotic method
US5545638A (en) * 1993-12-21 1996-08-13 Novo Nordisk A/S Method of treating gastrointestinal motility disorders
IL112024A (en) * 1993-12-21 1999-07-14 Novo Nordisk As Pharmaceutical compositions comprising tetrahydropyridine derivatives substituted with oxadiazole or thiadiazole for treating gastrointestinal motility disorders
US5605908A (en) * 1994-10-24 1997-02-25 Eli Lilly And Company Heterocyclic compounds and their use
US5672709A (en) * 1994-10-24 1997-09-30 Eli Lilly And Company Heterocyclic compounds and their preparation and use
US5998404A (en) * 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5484794A (en) * 1994-11-09 1996-01-16 Eli Lilly And Company Method for treating anxiety
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US5726193A (en) * 1994-10-31 1998-03-10 Eli Lilly And Company Method for treating anxiety
US5574028A (en) * 1994-10-31 1996-11-12 Eli Lilly And Company Method for treating anxiety
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US5565475A (en) * 1994-11-08 1996-10-15 Muhlhauser; Mark A. Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives
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US5605701A (en) * 1995-02-17 1997-02-25 Eli Lilly And Company Transdermal formulation
US5852037A (en) * 1995-11-13 1998-12-22 Eli Lilly And Company Method for treating anxiety
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US5998434A (en) * 1995-12-06 1999-12-07 Eli Lilly And Company Composition for treating pain
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AU2991397A (en) * 1996-04-23 1997-11-12 Eli Lilly And Company Heterocyclic compounds
CA2252573A1 (en) * 1996-04-23 1997-10-30 Celia Ann Whitesitt Heterocyclic compounds
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US6043258A (en) * 1996-08-01 2000-03-28 Eli Lilly And Company Method for treating disruptive behavior disorders with xanomeline
US6090829A (en) * 1996-08-01 2000-07-18 Eli Lilly And Company Method for treating excessive aggression
EP0821957A3 (en) * 1996-08-01 1998-04-22 Eli Lilly And Company Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) for treating substance abuse
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US6096767A (en) 1999-01-22 2000-08-01 The University Of Toledo Muscarinic receptor agonists
US6376675B2 (en) * 1999-01-22 2002-04-23 The University Of Toledo Muscarinic receptor agonists
US6211204B1 (en) 1999-01-22 2001-04-03 University Of Toledo Muscarinic receptor agonists
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NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IL83275A (en) * 1986-09-08 1994-02-27 Novo Nordisk As Compounds 1,2, 4-Oxadiazolyl Pipridine Transformed, their preparation and pharmaceutical preparations containing them
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DK162892C (da) * 1988-07-04 1992-05-11 Novo Nordisk As 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
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US5260311A (en) * 1989-02-22 1993-11-09 Novo Nordisk A/S Piperidine compounds and their use
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5175166A (en) * 1991-08-27 1992-12-29 The University Of Toledo Muscarinic agonists

Also Published As

Publication number Publication date
GR3017062T3 (en) 1995-11-30
JPH02255679A (ja) 1990-10-16
FI95704C (sv) 1996-03-11
FI900886A0 (sv) 1990-02-22
CN1045104A (zh) 1990-09-05
EP0384288B1 (en) 1995-05-24
FI900887A0 (fi) 1990-02-22
DE69019550D1 (de) 1995-06-29
PH26465A (en) 1992-07-27
KR0163763B1 (ko) 1998-12-01
NO900830L (no) 1990-08-23
JPH02255680A (ja) 1990-10-16
DE69019550T2 (de) 1995-10-05
PT93241B (pt) 1996-01-31
IL93352A (en) 1994-08-26
CA2010578C (en) 2000-05-23
AR247565A1 (es) 1995-01-31
NZ232615A (en) 1992-06-25
US5284859A (en) 1994-02-08
EP0384285A3 (en) 1991-04-24
IL93423A0 (en) 1990-11-29
US5041455A (en) 1991-08-20
DK0384288T3 (da) 1995-10-02
HUT58326A (en) 1992-02-28
KR910015569A (ko) 1991-09-30
IL93352A0 (en) 1990-11-29
NO900831L (no) 1990-08-23
IE69672B1 (en) 1996-10-02
HU900884D0 (en) 1990-05-28
ATE123030T1 (de) 1995-06-15
JP2921578B2 (ja) 1999-07-19
CA2010578A1 (en) 1990-08-22
NO900830D0 (no) 1990-02-21
RU2042676C1 (ru) 1995-08-27
NO900831D0 (no) 1990-02-21
AU629302B2 (en) 1992-10-01
HU211705A9 (en) 1995-12-28
NO179639C (no) 1996-11-20
AU4999690A (en) 1990-08-30
PT93241A (pt) 1990-08-31
HU221623B1 (hu) 2002-12-28
EP0384288A2 (en) 1990-08-29
PT93242A (pt) 1990-08-31
CN1028105C (zh) 1995-04-05
CA2010579A1 (en) 1990-08-22
US5043345A (en) 1991-08-27
ES2072323T3 (es) 1995-07-16
AU4999790A (en) 1990-08-30
EP0384288A3 (en) 1991-04-10
US5559138A (en) 1996-09-24
IE900504L (en) 1990-08-22
NO179639B (no) 1996-08-12
US5712297A (en) 1998-01-27
EP0384285A2 (en) 1990-08-29

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