FI954394A0 - 17-desoksikortikosteroidi-21-(O)-karboksyylihappoestereitä, menetelmä niiden valmistamiseksi ja niitä sisältäviä lääkkeitä - Google Patents

17-desoksikortikosteroidi-21-(O)-karboksyylihappoestereitä, menetelmä niiden valmistamiseksi ja niitä sisältäviä lääkkeitä

Info

Publication number: FI954394A0
Authority: FI; Finland
Prior art keywords: carboxylic acid; opt; deoxycorticosteroid; preparation; acid esters
Prior art date: 1994-09-20

Application number

FI954394A

Other languages

English (en)

Swedish (sv)

Other versions

FI114708B (fi

FI954394L (fi

Inventor

Ulrich Stache

Hans-Georg Alpermann

Manfred Bohn

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-20

Filing date

1995-09-18

Publication date

1995-09-18

1995-09-18 Application filed by Hoechst Ag filed Critical Hoechst Ag

1995-09-18 Publication of FI954394A0 publication Critical patent/FI954394A0/fi

1996-03-21 Publication of FI954394L publication Critical patent/FI954394L/fi

2004-12-15 Application granted granted Critical

2004-12-15 Publication of FI114708B publication Critical patent/FI114708B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI954394A 1994-09-20 1995-09-18 17-desoksikortikosteroidi-21-[O]-karboksyylihappoestereitä, menetelmä niiden valmistamiseksi ja niitä sisältäviä lääkkeitä FI114708B (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4433374		1994-09-20
DE4433374A DE4433374A1 (de)	1994-09-20	1994-09-20	17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (3)

Publication Number	Publication Date
FI954394A0 true FI954394A0 (fi)	1995-09-18
FI954394L FI954394L (fi)	1996-03-21
FI114708B FI114708B (fi)	2004-12-15

Family

ID=6528610

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI954394A FI114708B (fi)	1994-09-20	1995-09-18	17-desoksikortikosteroidi-21-[O]-karboksyylihappoestereitä, menetelmä niiden valmistamiseksi ja niitä sisältäviä lääkkeitä

Country Status (24)

Country	Link
US (1)	US5824670A (fi)
EP (1)	EP0708111B1 (fi)
JP (1)	JP3902255B2 (fi)
KR (1)	KR100406627B1 (fi)
CN (1)	CN1056151C (fi)
AT (1)	ATE188480T1 (fi)
AU (1)	AU695710B2 (fi)
CA (1)	CA2158610C (fi)
CZ (1)	CZ288297B6 (fi)
DE (2)	DE4433374A1 (fi)
DK (1)	DK0708111T3 (fi)
ES (1)	ES2140596T3 (fi)
FI (1)	FI114708B (fi)
GR (1)	GR3032688T3 (fi)
HU (1)	HU217438B (fi)
IL (1)	IL115331A (fi)
NO (1)	NO305210B1 (fi)
NZ (1)	NZ280038A (fi)
PL (1)	PL186071B1 (fi)
PT (1)	PT708111E (fi)
RU (1)	RU2161624C2 (fi)
SI (1)	SI9500295B (fi)
TW (1)	TW424094B (fi)
ZA (1)	ZA957877B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2012011106A1 (en) *	2010-07-20	2012-01-26	Taro Pharmaceutical Industries Ltd.	Process for the preparation of 17-desoxy-corticosteroids
US12209988B2 (en)	2019-05-24	2025-01-28	Electronics And Telecommunications Research Institute	Sensor and method of manufacturing the same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2755292A (en) *	1952-01-21	1956-07-17	Organon Labor Ltd	Phenyl propionate of testosterone
US2783226A (en) *	1955-02-03	1957-02-26	Schering Corp	Esters of cortical hormones
ES229413A1 (es) *	1956-06-22	1956-11-01	Francisco Vismara S P A	UN PROCEDIMIENTO PARA LA PREPARACIoN DE COMPUESTOS ESTEROIDALES QUE CONTENGAN UN GRUPO CEToLICO EN LA CADENA LATERAL
DE1131668B (de) *	1959-07-16	1962-06-20	Leo Ab	Verfahren zur Herstellung von Estern von Corticosteroid-Hormonen
CH495969A (de) *	1965-11-09	1970-09-15	Schering Ag	Verfahren zur Herstellung neuer 21-Ester von 16a-Methyl-21-hydroxy- 1,4-steroiden
DE2047105C3 (de) *	1970-09-18	1979-02-15	Schering Ag, 1000 Berlin Und 4619 Bergkamen	17-Chlorsteroide und Verfahren zu ihrer Herstellung
US3956349A (en) *	1975-02-18	1976-05-11	Syntex (U.S.A.) Inc.	Process for preparing 3-enol ethers of 11β-hydroxy-Δ4 -pregnene-3-ones and derivatives thereof
FR2342738A1 (fr) *	1976-03-02	1977-09-30	Roussel Uclaf	Nouveaux derives halogenes de la serie du 16a-methyl pregnane
DE2617655C2 (de) *	1976-04-21	1984-11-08	F. Hoffmann-La Roche & Co Ag, Basel	Kortikoide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE2645104C2 (de) *	1976-10-04	1986-04-24	Schering AG, 1000 Berlin und 4709 Bergkamen	11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung
FR2381065A2 (fr) *	1977-02-22	1978-09-15	Roussel Uclaf	Nouveaux derives halogenes de la serie du 16 a-methyl pregnane
US4086254A (en) *	1977-04-13	1978-04-25	The Upjohn Company	Photocleavable steroids
LU77457A1 (fi) *	1977-05-31	1979-01-19
US4377573A (en) *	1978-01-06	1983-03-22	Leveen Harry H	Method of control of gastrointestinal bleeding
DE2817988A1 (de) *	1978-04-25	1979-11-08	Hoechst Ag	Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
DE2920726A1 (de) *	1979-05-18	1980-11-27	Schering Ag	Neue kortikoide, ihre herstellung und verwendung
ATE8790T1 (de) *	1981-02-02	1984-08-15	Schering Corporation	Aromatische heterocyclische steroidester, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
SE8303031D0 (sv) *	1983-05-30	1983-05-30	Leo Ab	Improved steroid esters preparation
US4920114A (en) *	1988-06-28	1990-04-24	Merrell Dow Pharmaceuticals Inc.	19-fluoro- or cyano-21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors
US4910191A (en) *	1988-06-28	1990-03-20	Merrell Dow Pharmaceuticals Inc.	19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
ZA912235B (en) *	1990-04-02	1991-12-24	Merrell Dow Pharma	Haloethyl-substituted steroidal enzyme inhibitors

1994
- 1994-09-20 DE DE4433374A patent/DE4433374A1/de not_active Withdrawn
1995
- 1995-09-08 TW TW084109384A patent/TW424094B/zh not_active IP Right Cessation
- 1995-09-15 DE DE59507565T patent/DE59507565D1/de not_active Expired - Lifetime
- 1995-09-15 DK DK95114511T patent/DK0708111T3/da active
- 1995-09-15 ES ES95114511T patent/ES2140596T3/es not_active Expired - Lifetime
- 1995-09-15 PT PT95114511T patent/PT708111E/pt unknown
- 1995-09-15 EP EP95114511A patent/EP0708111B1/de not_active Expired - Lifetime
- 1995-09-15 AT AT95114511T patent/ATE188480T1/de active
- 1995-09-18 NZ NZ280038A patent/NZ280038A/en not_active IP Right Cessation
- 1995-09-18 CN CN95116294A patent/CN1056151C/zh not_active Expired - Fee Related
- 1995-09-18 CZ CZ19952425A patent/CZ288297B6/cs not_active IP Right Cessation
- 1995-09-18 FI FI954394A patent/FI114708B/fi not_active IP Right Cessation
- 1995-09-18 US US08/529,668 patent/US5824670A/en not_active Expired - Lifetime
- 1995-09-18 AU AU31728/95A patent/AU695710B2/en not_active Ceased
- 1995-09-18 IL IL11533195A patent/IL115331A/en not_active IP Right Cessation
- 1995-09-19 ZA ZA957877A patent/ZA957877B/xx unknown
- 1995-09-19 PL PL95310544A patent/PL186071B1/pl not_active IP Right Cessation
- 1995-09-19 NO NO953695A patent/NO305210B1/no not_active IP Right Cessation
- 1995-09-19 CA CA002158610A patent/CA2158610C/en not_active Expired - Fee Related
- 1995-09-19 JP JP23939895A patent/JP3902255B2/ja not_active Expired - Fee Related
- 1995-09-19 RU RU95116371/04A patent/RU2161624C2/ru not_active IP Right Cessation
- 1995-09-19 HU HU9502735A patent/HU217438B/hu not_active IP Right Cessation
- 1995-09-20 KR KR1019950030850A patent/KR100406627B1/ko not_active Expired - Fee Related
- 1995-09-20 SI SI9500295A patent/SI9500295B/sl unknown
2000
- 2000-02-18 GR GR20000400386T patent/GR3032688T3/el unknown

Also Published As

Publication number	Publication date
GR3032688T3 (en)	2000-06-30
HUT72969A (en)	1996-06-28
NZ280038A (en)	1997-03-24
PT708111E (pt)	2000-04-28
IL115331A0 (en)	1995-12-31
CA2158610A1 (en)	1996-03-21
NO305210B1 (no)	1999-04-19
DE4433374A1 (de)	1996-03-21
CZ242595A3 (en)	1996-04-17
NO953695D0 (no)	1995-09-19
NO953695L (no)	1996-03-21
CN1124250A (zh)	1996-06-12
JP3902255B2 (ja)	2007-04-04
SI9500295A (en)	1996-04-30
AU3172895A (en)	1996-04-04
ATE188480T1 (de)	2000-01-15
US5824670A (en)	1998-10-20
HU9502735D0 (en)	1995-11-28
RU2161624C2 (ru)	2001-01-10
DE59507565D1 (de)	2000-02-10
CZ288297B6 (en)	2001-05-16
SI9500295B (en)	2001-12-31
CA2158610C (en)	2007-07-17
PL310544A1 (en)	1996-04-01
KR100406627B1 (ko)	2004-02-19
FI114708B (fi)	2004-12-15
IL115331A (en)	2002-07-25
DK0708111T3 (da)	2000-06-13
ES2140596T3 (es)	2000-03-01
AU695710B2 (en)	1998-08-20
FI954394L (fi)	1996-03-21
EP0708111B1 (de)	2000-01-05
TW424094B (en)	2001-03-01
JPH0899992A (ja)	1996-04-16
KR960010681A (ko)	1996-04-20
CN1056151C (zh)	2000-09-06
EP0708111A1 (de)	1996-04-24
PL186071B1 (pl)	2003-10-31
ZA957877B (en)	1996-04-03
HU217438B (hu)	2000-01-28

Publication	Publication Date	Title
ATE71375T1 (de)	1992-01-15	Substituierte 6-fluor-4-oxo-1,4-dihydrochinolin-3-carbonsaeure ; deren derivate; diese verbindung enthaltende pharmazeutische zubereitungen und verfahren zur herstellung dieser verbindungen.
FR2678938B1 (fr)	1993-10-08	Derives de pyrrolidine, leur preparation et les medicaments les contenant.
FR2680507B1 (fr)	1993-10-08	Nouvelles naphtylethylurees et naphtylethylthiourees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
ATE121739T1 (de)	1995-05-15	Discodermolideverbindungen, diese enthaltende zubereitungen, verfahren zu ihrer herstellung und deren verwendung.
ATE235482T1 (de)	2003-04-15	Isocumarinderivate und deren verwendung in medikamenten
ATE102210T1 (de)	1994-03-15	1h,3h,7-pyrrolo (1,2-c>thiazolcarbonsaeureamidderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
FI954394A0 (fi)	1995-09-18	17-desoksikortikosteroidi-21-(O)-karboksyylihappoestereitä, menetelmä niiden valmistamiseksi ja niitä sisältäviä lääkkeitä
ATE55250T1 (de)	1990-08-15	Ifosfamid-lyophilisat und verfahren zu dessen herstellung.
ATE36710T1 (de)	1988-09-15	Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung.
ATE53209T1 (de)	1990-06-15	Piperazinverbindungen, verfahren zu ihrer herstellung, pharmazeutische zusammensetzung und verwendung.
EP0318029A3 (en)	1990-09-26	Cyclic amine and pharmacological composition
HUT58097A (en)	1992-01-28	Process for producing 3,7-diazobicyclo(3,3.1)nonane compounds and pharmaceutical compositions comprising same
DE3886185D1 (de)	1994-01-20	2-Thiazolidinon-Derivate und diese enthaltende pharmazeutische Präparate, Verfahren zu deren Herstellung und deren Verwendung.
DE69116423D1 (de)	1996-02-29	3'-Deamino-4'-deoxy-4'-amino-8-fluoranthracycline und Verfahren zu ihrer Herstellung
ATE99663T1 (de)	1994-01-15	Neue leukotrien-b4-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE101119T1 (de)	1994-02-15	Butensaeure-amide, deren salze, diese enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung.
DE59105961D1 (de)	1995-08-17	2,13-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln.
ATE159011T1 (de)	1997-10-15	Stereoselektives verfahren zur herstellung von 2- amino-ethanol-derivaten mit zentralanalgetischer aktivität und zwischenprodukten
FR2655042B1 (fr)	1994-01-21	Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
ATE104276T1 (de)	1994-04-15	Salze von acrylsaeure, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die sie enthalten und deren verwendung in der medizin.
FR2573428B1 (fr)	1987-01-30	Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
DE3784883D1 (de)	1993-04-22	Fluor enthaltende makrolid-verbindungen, pharmazeutische zusammensetzungen, welche diese enthalten und ihre verwendung fuer die herstellung von arzneimitteln.
DE69011952D1 (de)	1994-10-06	Physiologisch aktive Verbindungen SN-198C sowie Verfahren und Bakterien zu deren Herstellung.

Legal Events

Date	Code	Title	Description
2015-04-22	MM	Patent lapsed