[go: up one dir, main page]

FI953327A - Uudet 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-oni- ja oksatsolo(4,5-b)-pyridin-2(3H)-oniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset valmisteet - Google Patents

Uudet 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-oni- ja oksatsolo(4,5-b)-pyridin-2(3H)-oniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset valmisteet Download PDF

Info

Publication number
FI953327A
FI953327A FI953327A FI953327A FI953327A FI 953327 A FI953327 A FI 953327A FI 953327 A FI953327 A FI 953327A FI 953327 A FI953327 A FI 953327A FI 953327 A FI953327 A FI 953327A
Authority
FI
Finland
Prior art keywords
pyridin
oxazolo
pyrrolo
dihydro
compounds
Prior art date
Application number
FI953327A
Other languages
English (en)
Swedish (sv)
Other versions
FI953327A0 (fi
Inventor
Gerald Guillaumet
Marie-Claude Viaud
Laurence Savelon
Panayota Pavli
Pierre Renard
Bruno Pfeiffer
Daniel-Henri Caignard
Jean-Guy Bizot-Espiard
Gerard Adam
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9408418A external-priority patent/FR2722195B1/fr
Priority claimed from FR9408419A external-priority patent/FR2722196B1/fr
Application filed by Adir filed Critical Adir
Publication of FI953327A0 publication Critical patent/FI953327A0/fi
Publication of FI953327A publication Critical patent/FI953327A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI953327A 1994-07-07 1995-07-06 Uudet 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-oni- ja oksatsolo(4,5-b)-pyridin-2(3H)-oniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset valmisteet FI953327A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9408418A FR2722195B1 (fr) 1994-07-07 1994-07-07 Nouveaux derives de 1,3-dihydro-2h-pyrrolo(2,3-b) pyridin-2-ones et oxazolo(4,5-b) pyridin-2(3h)-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR9408419A FR2722196B1 (fr) 1994-07-07 1994-07-07 Nouveaux derives amines de 1,3-dihydro-2h-pyrrolo(2,3-b) pyridin-2-ones et oxazolo(4,5-b) pyridin-2 (3h)-ones, leur procede de preparation et les compositions pharmaceutique qui les contiennent

Publications (2)

Publication Number Publication Date
FI953327A0 FI953327A0 (fi) 1995-07-06
FI953327A true FI953327A (fi) 1996-01-08

Family

ID=26231276

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953327A FI953327A (fi) 1994-07-07 1995-07-06 Uudet 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-oni- ja oksatsolo(4,5-b)-pyridin-2(3H)-oniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset valmisteet

Country Status (9)

Country Link
US (2) US5618819A (fi)
EP (1) EP0691339A1 (fi)
JP (1) JPH0853447A (fi)
CN (1) CN1127254A (fi)
AU (1) AU683167B2 (fi)
CA (1) CA2153294A1 (fi)
FI (1) FI953327A (fi)
NO (1) NO952677L (fi)
NZ (1) NZ272516A (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618819A (en) * 1994-07-07 1997-04-08 Adir Et Compagnie 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-(3H)-one compounds
US6166274A (en) * 1999-12-15 2000-12-26 Atofina Chemicals, Inc. Catalyzed liquid phase fluorination of 1230za
CA2585544A1 (en) * 2004-10-27 2006-05-11 Janssen Pharmaceutica N.V. Pyridine imidazoles and aza-indoles as progesterone receptor modulators
DE102005007694A1 (de) * 2005-02-18 2006-09-21 Henkel Kgaa Mittel zum Färben von keratinhaltigen Fasern
MY145694A (en) * 2005-04-11 2012-03-30 Xenon Pharmaceuticals Inc Spiroheterocyclic compounds and their uses as therapeutic agents
MY144968A (en) * 2005-04-11 2011-11-30 Xenon Pharmaceuticals Inc Spiro-oxindole compounds and their uses as therapeutic agents
AR053713A1 (es) * 2005-04-20 2007-05-16 Xenon Pharmaceuticals Inc Compuestos heterociclicos y sus usos como agentes terapeuticos
US8604031B2 (en) * 2006-05-18 2013-12-10 Mannkind Corporation Intracellular kinase inhibitors
AU2007307635A1 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Tricyclic spiro-oxindole derivatives and their uses as therapeutic agents
ATE545416T1 (de) * 2006-10-12 2012-03-15 Xenon Pharmaceuticals Inc Verwendung von spiro-oxindol-verbindungen als therapeutika
AU2007307638A1 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Spiro (furo [3, 2-C] pyridine-3-3 ' -indol) -2' (1'H)-one derivatives and related compounds for the treatment of sodium-channel mediated diseases, such as pain
JPWO2009025265A1 (ja) * 2007-08-21 2010-11-25 塩野義製薬株式会社 ピペラジン誘導体
WO2010045197A1 (en) * 2008-10-17 2010-04-22 Xenon Pharmaceuticals, Inc. Spiro-oxindole compounds and their use as therapeutic agents
CN106928247A (zh) * 2008-10-17 2017-07-07 泽农医药公司 螺羟吲哚化合物及其作为治疗剂的用途
EP3037421A3 (en) 2008-11-25 2016-11-30 University Of Rochester Mlk inhibitors and methods of use
AR077252A1 (es) 2009-06-29 2011-08-10 Xenon Pharmaceuticals Inc Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
WO2011047173A2 (en) * 2009-10-14 2011-04-21 Xenon Pharmaceuticals Inc. Pharmaceutical compositions for oral administration
EP2733145A1 (en) 2009-10-14 2014-05-21 Xenon Pharmaceuticals Inc. Synthetic methods for spiro-oxindole compounds
RU2596488C2 (ru) 2010-02-26 2016-09-10 Ксенон Фармасьютикалз Инк. Фармацевтические композиции спиро-оксиндольного соединения для местного введения и их применение в качестве терапевтических агентов
JP6086326B2 (ja) 2010-05-24 2017-03-01 ユニヴァーシティー オブ ロチェスター 二環式ヘテロアリールキナーゼ阻害剤および使用方法
US20140113824A1 (en) 2011-05-10 2014-04-24 Bayer Intellectual Property Gmbh Bicyclic (thio)carbonylamidines
US9056829B2 (en) * 2011-09-01 2015-06-16 Dsm Ip Assets B.V. Process for the alkoxycarbonylation of functionalized alkenes
EP2925319B1 (en) 2012-11-30 2019-01-09 University Of Rochester Mixed lineage kinase inhibitors for hiv/aids therapies
MA41169A (fr) * 2014-12-17 2017-10-24 Acraf Composés antibactériens à large spectre d'activité
TW201636017A (zh) 2015-02-05 2016-10-16 梯瓦製藥國際有限責任公司 以螺吲哚酮化合物之局部調配物治療帶狀疱疹後遺神經痛之方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2244507A1 (en) * 1973-06-26 1975-04-18 Inst Nat Sante Rech Med Chalcones and analogues - analgesics having low toxicity
US4038396A (en) * 1975-02-24 1977-07-26 Merck & Co., Inc. Anti-inflammatory oxazole[4,5-b]pyridines
JPS6015635B2 (ja) * 1976-05-28 1985-04-20 久光製薬株式会社 新規なオキサゾロ〔４，５−ｂ〕ピリジン誘導体
US4822794A (en) * 1987-05-08 1989-04-18 Rorer Pharmaceutical Corporation Pyridooxazinone-pyridone compounds, cardiotonic compositions including the same, and their uses
US4866074A (en) * 1987-05-08 1989-09-12 Rorer Pharmaceutical Corporation Naphtheridinone- and pyridooxazinone-pyridone compounds, cardiotonic compositions including same, and their uses
FR2650591B1 (fr) * 1989-08-07 1991-11-15 Science Organisation Nouveaux derives d'oxazolo pyridines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2652085A1 (fr) * 1989-09-20 1991-03-22 Science Organisation Nouveau procede de synthese de derives d'oxazolopyridines.
WO1991009598A1 (en) * 1990-01-05 1991-07-11 Pfizer Inc. Azaoxindole derivatives
FR2663929A1 (fr) * 1990-06-29 1992-01-03 Adir Nouveaux derives d'oxazolo pyridines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2669336B1 (fr) * 1990-11-20 1993-01-22 Adir Nouveaux derives d'oxazolo pyridines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5618819A (en) * 1994-07-07 1997-04-08 Adir Et Compagnie 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-(3H)-one compounds

Also Published As

Publication number Publication date
CA2153294A1 (fr) 1996-01-08
NZ272516A (en) 1996-10-28
JPH0853447A (ja) 1996-02-27
EP0691339A1 (fr) 1996-01-10
AU2482795A (en) 1996-01-18
US5767128A (en) 1998-06-16
NO952677D0 (no) 1995-07-06
NO952677L (no) 1996-01-08
FI953327A0 (fi) 1995-07-06
CN1127254A (zh) 1996-07-24
US5618819A (en) 1997-04-08
AU683167B2 (en) 1997-10-30

Similar Documents

Publication Publication Date Title
FI953327A (fi) Uudet 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-oni- ja oksatsolo(4,5-b)-pyridin-2(3H)-oniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset valmisteet
ZA875151B (en) Imidazo(4,5-b)pyridine compounds,process for preparing same and pharmaceutical compositions containing same
HUP0103137A3 (en) Oxazolo, thiazolo and selenazolo-[4,5-c]-quinolin-4-amines and analogs thereof, process for their preparation, pharmaceutical compositions containing them and their use
HUP0001805A3 (en) 6-benzyl-1,5-dihydro-pyrazolo[3,4-d]-pyrimidin-4-one derivatives, process for their preparation and pharmaceutical compositions containing them
HUT42089A (en) Process for preparing 1,2-dihydro-2h-imidazo/4,5-b/quinolin-2-one derivatives
HUP0200450A3 (en) Cephen derivatives containing an imidazo[4,5-b]pyridiniummethyl moiety, process for their preparation and pharmaceutical compositions of the same
HUT41771A (en) Process for producing benzimidazol derivatives, imidazo/4,5-b/pyridine derivatives and pharmaceutical compositions containing them
FI91529B (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten pyrido/1,2,3-de//1,4/bentsoksatsiinijohdannaisten valmistamiseksi
ZA955672B (en) 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2(3H)-one compounds a process for their preparation and pharmaceutical compositions containing them
NZ218880A (en) Pyrido(2,3-b)indole-3-carboxylic acid derivatives and pharmaceutical compositions thereof
EP0554098A3 (en) Process for the preparation of imidazo 4,5-b pyridine derivatives
MX6710E (es) Procedimiento para la preparacion de 10-(4-substituido-1-piperazinil)-2,4-dihidro-1,2,3-triazol(4,5-b)(1,5)-benzodiazepina
HU197910B (en) Process for producing 6h-isoxazolo/5,4-d/pyrazolo/3,4-b/pyridines and pharmaceutical compositions comprising such compounds
HUT45253A (en) Process for producing imidazo/4,5-b/pyridin-2-one derivatives and pharmaceutical compositions containing them
HUT57776A (en) Process for producing pyrido(3,4-b)(1,4)benzoxazepine derivatives and pharmaceutical compositions comprising same
IL65977A (en) 1,4,9,10-tetrahydropyrazolo(4,3-e)pyrido(3,2-b)(1,4)diazepin-10-one derivatives,their preparation and pharmaceutical compositions containing them
IL82532A0 (en) Pyrazolo(3,4-b)pyridine derivatives,processes for the preparation thereof and herbicidal compositions containing the same
FI820982L (fi) Nya 1,2-dihydropyrido/3,4-b/pyraziner och foerfarande och mellanprodukter foer framstaellning av desamma
IL78164A0 (en) 5-h pyrido(3',4'-:4,5)pyrrolo(3,2-c)-pyridine derivatives,their preparation and pharmaceutical compositions containing them
IL65555A (en) 5-pyridyl-1h-pyrazolo(3,4-b)pyridin-3-amine derivatives,their preparation and pharmaceutical compositions containing them
AU7787481A (en) Thiazolo(3,:2:,1,2)imidazo(4,5-b)pyridine derivatives
PT84310B (en) Pyrrolo ]3,4-b" pyridine derivatives process for the preparation thereof and pharmaceutical compositions containing them
HUT68172A (en) Process for the preparation of substituted d, l-2-(7-fluoro-3,4-dihidro-3-oxo-2h-1,4-benzoxazin-6-yl)-perhydroimidazo[1,5-a]pyridine-1,3-diones
FR2722196B1 (fr) Nouveaux derives amines de 1,3-dihydro-2h-pyrrolo(2,3-b) pyridin-2-ones et oxazolo(4,5-b) pyridin-2 (3h)-ones, leur procede de preparation et les compositions pharmaceutique qui les contiennent
GB8809176D0 (en) Pyrido(3 4-b)indole derivatives & process for their preparation