FI943207L - Framställningförfarande och användning av 4,5-dihydrogeldanamycin och dess hydrokinon - Google Patents

Framställningförfarande och användning av 4,5-dihydrogeldanamycin och dess hydrokinon Download PDF

Info

Publication number: FI943207L
Authority: FI; Finland
Prior art keywords: dihydrogeldanamycin; hydroquinone; preparing
Prior art date: 1992-01-06

Application number

FI943207A

Other languages

English (en)

Finnish (fi)

Other versions

FI943207A0 (sv

Inventor

Walter P Cullen

Mark T Jefferson

Mikel P Moyer

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-06

Filing date

1994-07-05

Publication date

1994-07-05

1994-07-05 Application filed by Pfizer filed Critical Pfizer

1994-07-05 Publication of FI943207L publication Critical patent/FI943207L/sv

1994-07-05 Publication of FI943207A0 publication Critical patent/FI943207A0/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Immunology (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

FI943207A 1992-01-06 1994-07-05 Framställningförfarande och användning av 4,5-dihydrogeldanamycin och dess hydrokinon FI943207A0 (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US81723592A	1992-01-06	1992-01-06
PCT/US1992/010189 WO1993014215A1 (en)	1992-01-06	1992-12-03	Process and uses for 4,5-dihydrogeldanamycin and its hydroquinone

Publications (2)

Publication Number	Publication Date
FI943207L true FI943207L (sv)	1994-07-05
FI943207A0 FI943207A0 (sv)	1994-07-05

Family

ID=25222638

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI943207A FI943207A0 (sv)	1992-01-06	1994-07-05	Framställningförfarande och användning av 4,5-dihydrogeldanamycin och dess hydrokinon

Country Status (15)

Country	Link
JP (1)	JPH06510913A (sv)
KR (1)	KR940703923A (sv)
CN (1)	CN1074937A (sv)
AU (1)	AU3225693A (sv)
BR (1)	BR9207024A (sv)
CA (1)	CA2127457A1 (sv)
CZ (1)	CZ390592A3 (sv)
FI (1)	FI943207A0 (sv)
HU (1)	HU9401936D0 (sv)
IL (1)	IL104289A0 (sv)
MX (1)	MX9300011A (sv)
NO (1)	NO942532D0 (sv)
PT (1)	PT101169A (sv)
WO (1)	WO1993014215A1 (sv)
ZA (1)	ZA9333B (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2166320A1 (en) *	1993-06-29	1995-01-12	Randall James Gallaschun	Ansamycin derivatives as antioncogene and anticancer agents
US5932566A (en) *	1994-06-16	1999-08-03	Pfizer Inc.	Ansamycin derivatives as antioncogene and anticancer agents
US6852496B1 (en)	1997-08-12	2005-02-08	Oregon Health And Science University	Methods of screening for agents that promote nerve cell growth
US6872715B2 (en)	2001-08-06	2005-03-29	Kosan Biosciences, Inc.	Benzoquinone ansamycins
CA2460498A1 (en)	2001-09-24	2003-04-03	Conforma Therapeutics Corporation	Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins
EP1923061A1 (en)	2001-09-24	2008-05-21	Conforma Therapeutic Corporation	Process for preparing 17-Allyl amino geldanamycin (17-AAG) and other ansamycins
DE60327994D1 (de)	2002-02-08	2009-07-30	Conforma Therapeutics Corp	Ansamycine mit verbesserten pharmakologischen und biologischen eigenschaften
TW200303363A (en) *	2002-02-25	2003-09-01	Upjohn Co	Process to prepare and isolate geldanamycin
WO2005009345A2 (en)	2003-06-13	2005-02-03	Kosan Biosciences, Inc.	2-desmethyl ansamycin compounds
US6870049B1 (en)	2003-11-12	2005-03-22	Kosan Biosciences, Inc.	11-O-methylgeldanamycin compounds
US6855705B1 (en)	2003-11-12	2005-02-15	Kosan Biosciences, Inc.	11-O-methylgeldanamycin compounds
US6887993B1 (en)	2003-11-12	2005-05-03	Kosan Biosciences, Inc.	11-O-methylgeldanamycin compounds
US6875863B1 (en)	2003-11-12	2005-04-05	Kosan Biosciences, Inc.	11-O-methylgeldanamycin compounds
JP2007512369A (ja) *	2003-11-26	2007-05-17	エンテロス・インコーポレーテッド	低酸素誘導因子１αアンタゴニストを用いる慢性関節リウマチの処置
CN1898212B (zh) *	2003-12-23	2012-06-13	无限发现公司	用于治疗癌症的包含苯醌的安沙霉素类似物
US20060019941A1 (en) *	2003-12-23	2006-01-26	Infinity Pharmaceuticals, Inc.	Analogs of benzoquinone-containing ansamycins and methods of use thereof
BRPI0418147A (pt)	2003-12-23	2007-04-17	Infinity Pharmaceuticals Inc	análogos de ansamicinas contendo benzoquinona e seus métodos de uso
KR20080004550A (ko)	2005-03-30	2008-01-09	콘포마 세러퓨틱스 코포레이션	Ｈｓｐ９０-억제제로서 알키닐 피롤로피리미딘 및 관련유사체
AU2007319014B2 (en) *	2006-11-09	2013-03-28	Bristol-Myers Squibb Company	Novel compounds and methods for their production
PE20081506A1 (es)	2006-12-12	2008-12-09	Infinity Discovery Inc	Formulaciones de ansamicina
CN100500668C (zh) *	2006-12-19	2009-06-17	中国人民解放军军事医学科学院毒物药物研究所	格尔德霉素衍生物及其制备方法和制备药物的用途
EP2121957A4 (en)	2007-01-26	2010-11-10	Kosan Biosciences Inc	MACROLACTAMES OBTAINED BY MODIFIED BIOSYNTHESIS
EP2297109A4 (en) *	2008-04-21	2011-06-22	Biocon Ltd	METHOD FOR ISOLATING AND PURIFYING GELDANAMYCIN
WO2010045442A1 (en)	2008-10-15	2010-04-22	Infinity Discovery, Inc.	Ansamycin hydroquinone compositions
CN102030764B (zh) *	2010-11-12	2012-07-04	中国医学科学院医药生物技术研究所	4，5双氢噻嗪酮格尔德霉素及其制备方法
CN103305563B (zh) *	2013-06-14	2014-12-03	湖南农业大学	一种以链霉菌提制阿里沙霉素的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3595955A (en) *	1969-03-26	1971-07-27	Upjohn Co	Geldanamycin and process for producing same

1992
- 1992-12-03 AU AU32256/93A patent/AU3225693A/en not_active Abandoned
- 1992-12-03 HU HU9401936A patent/HU9401936D0/hu unknown
- 1992-12-03 BR BR9207024A patent/BR9207024A/pt not_active Application Discontinuation
- 1992-12-03 KR KR1019940702334A patent/KR940703923A/ko not_active Application Discontinuation
- 1992-12-03 WO PCT/US1992/010189 patent/WO1993014215A1/en active Application Filing
- 1992-12-03 JP JP5512423A patent/JPH06510913A/ja active Pending
- 1992-12-03 CA CA002127457A patent/CA2127457A1/en not_active Abandoned
- 1992-12-15 CN CN92113885A patent/CN1074937A/zh active Pending
- 1992-12-28 CZ CS923905A patent/CZ390592A3/cs unknown
- 1992-12-31 IL IL104289A patent/IL104289A0/xx unknown
1993
- 1993-01-04 PT PT101169A patent/PT101169A/pt not_active Application Discontinuation
- 1993-01-05 MX MX9300011A patent/MX9300011A/es unknown
- 1993-01-05 ZA ZA9333A patent/ZA9333B/xx unknown
1994
- 1994-07-05 FI FI943207A patent/FI943207A0/sv unknown
- 1994-07-05 NO NO942532A patent/NO942532D0/no unknown

Also Published As

Publication number	Publication date
ZA9333B (en)	1994-07-05
CA2127457A1 (en)	1993-07-22
JPH06510913A (ja)	1994-12-08
NO942532L (no)	1994-07-05
MX9300011A (es)	1993-12-01
BR9207024A (pt)	1995-12-05
IL104289A0 (en)	1993-05-13
CN1074937A (zh)	1993-08-04
FI943207A0 (sv)	1994-07-05
NO942532D0 (no)	1994-07-05
PT101169A (pt)	1994-03-31
KR940703923A (ko)	1994-12-12
AU3225693A (en)	1993-08-03
WO1993014215A1 (en)	1993-07-22
CZ390592A3 (en)	1993-08-11
HU9401936D0 (en)	1994-09-28

Publication	Publication Date	Title
FI943207L (sv)	1994-07-05	Framställningförfarande och användning av 4,5-dihydrogeldanamycin och dess hydrokinon
FI951596L (sv)	1995-04-04	Förfarande för erhållande av 10-desacetylbakkatin III
FI955727L (sv)	1996-01-26	Förfarande och anordning för framställning av liposomer
FI960948L (sv)	1996-02-29	Förpackning och förfarande för produktion av förpackningen
FI946104L (sv)	1995-06-29	Synnerligen koncentrerat immunoglobulinpreparat och förfarande för framställning av detta
FI951184L (sv)	1995-09-17	Deg innefattande sammansättning och förfarande för dess framställning
FI942745L (sv)	1994-12-12	Fluorenföreningar och en metod för framställning
FI925913L (sv)	1994-06-30	Förfarande för polymerisation av -olefiner samt en förpolymeriserad katalysatorkomposition och ett förfarande för framställning därav
FI941538L (sv)	1994-05-31	Partiklar, ett förfarande för framställning av dem och deras användning
FI944961L (sv)	1994-10-21	Farmaceutiskt preparat och förfarande för dess framställning
FI962069L (sv)	1996-05-15	Förfarande för framställning av karpolaktam
FI935465L (sv)	1994-06-08	Termoplastisk komposition, foerfarande foer framstaellning av denna och anvaendning av denna
NO921218L (no)	1992-09-29	Reseptor-rensemetode
FI943383L (sv)	1994-08-31	Förening FO-1289 och ett förfarande för framställning av den
FI943532L (sv)	1994-07-27	Fluffmassa och saett vid beredning av fluffmassa
EP0499233A3 (en)	1992-09-16	Organopentasiloxane and method for its preparation
DE69302555D1 (de)	1996-06-13	Bremsverfahren
FI925357L (sv)	1994-05-26	Byggnadsförfarande
FI944713L (sv)	1994-12-02	4-difenylmetylpiperidinderivat och förfarande för deras framställning
FI921621L (fi)	1992-10-13	Sprutmetod foer braensle
FI955800L (sv)	1995-12-01	Metod att framställa aminoalkylguanidiner
FI940775L (sv)	1994-02-18	Förfarande för framställning av alfa-fenylisoserinderivat och användning av dem
FI944169L (sv)	1994-09-09	Förfarande för framställning av beta-fenylisoserin och dess analoger
DK96392D0 (da)	1992-07-27	Modifikationsmetode
FI944563L (sv)	1994-09-30	Mikroorganismer, framställningsförfarande och användning