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FI933252A0 - Nya amylinagonistpeptider och anvaendning som amylinagonister - Google Patents

Nya amylinagonistpeptider och anvaendning som amylinagonister

Info

Publication number
FI933252A0
FI933252A0 FI933252A FI933252A FI933252A0 FI 933252 A0 FI933252 A0 FI 933252A0 FI 933252 A FI933252 A FI 933252A FI 933252 A FI933252 A FI 933252A FI 933252 A0 FI933252 A0 FI 933252A0
Authority
FI
Finland
Prior art keywords
pro
ser
thr
asn
leu
Prior art date
Application number
FI933252A
Other languages
English (en)
Other versions
FI118601B (fi
FI933252L (fi
Inventor
Laura S L Gaeta
Howard Jones
Elisabeth Albrecht
Original Assignee
Amylin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc
Publication of FI933252A0 publication Critical patent/FI933252A0/fi
Publication of FI933252L publication Critical patent/FI933252L/fi
Application granted granted Critical
Publication of FI118601B publication Critical patent/FI118601B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI933252A 1991-11-19 1993-07-16 Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi FI118601B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79426691A 1991-11-19 1991-11-19
US79426691 1991-11-19
US9209842 1992-11-19
PCT/US1992/009842 WO1993010146A1 (en) 1991-11-19 1992-11-19 Amylin agonist peptides and uses therefor

Publications (3)

Publication Number Publication Date
FI933252A0 true FI933252A0 (fi) 1993-07-16
FI933252L FI933252L (fi) 1993-08-23
FI118601B FI118601B (fi) 2008-01-15

Family

ID=25162163

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933252A FI118601B (fi) 1991-11-19 1993-07-16 Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi

Country Status (17)

Country Link
EP (2) EP0567626B1 (fi)
JP (4) JP2902115B2 (fi)
AT (1) ATE205854T1 (fi)
AU (1) AU714439B2 (fi)
CA (1) CA2100745C (fi)
CZ (1) CZ288029B6 (fi)
DE (1) DE69232064T2 (fi)
DK (1) DK0567626T3 (fi)
ES (1) ES2161697T3 (fi)
FI (1) FI118601B (fi)
GR (1) GR3036794T3 (fi)
HK (1) HK1041891A1 (fi)
MD (1) MD960317A (fi)
NO (2) NO324405B1 (fi)
RU (1) RU2130463C1 (fi)
SK (1) SK88793A3 (fi)
WO (1) WO1993010146A1 (fi)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222249B1 (hu) 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US5625032A (en) * 1993-07-21 1997-04-29 Amylin Pharmaceuticals, Inc. Selective amylin antagonist peptides and uses therefor
ZA946881B (en) 1993-09-07 1995-10-30 Amylin Pharmaceuticals Inc Methods for treating gastrointestinal motility
US5739106A (en) * 1995-06-07 1998-04-14 Rink; Timothy J. Appetite regulating compositions
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
US7312196B2 (en) 1997-01-08 2007-12-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US6410511B2 (en) 1997-01-08 2002-06-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US7101853B2 (en) * 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
AU760609B2 (en) * 1998-01-09 2003-05-15 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
GB0128583D0 (en) 2001-11-28 2002-01-23 Rsr Ltd Detection of autoantibodies indicative of diabetes
US8168233B2 (en) 2002-10-18 2012-05-01 Amylin Pharmaceuticals, Inc. Treatment of pancreatitis with amylin
CA2516726A1 (en) * 2003-03-18 2004-09-30 Applied Research Systems Ars Holding N.V. Amylin aggregation inhibitors and use thereof
AU2005298840B2 (en) * 2004-10-26 2010-09-16 Lonza Ag S-alkyl-sulphenyl protection groups in solid-phase synthesis
US20090156474A1 (en) 2004-11-01 2009-06-18 Amylin Pharmaceuticals, Inc. Methods for treating obesity and obesity related diseases and disorders
US8394765B2 (en) 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
US7671023B2 (en) 2005-03-31 2010-03-02 Amylin Pharmaceuticals, Inc. Amylin agonist for treating depression, anxiety disorder and schizophrenia
US8168592B2 (en) 2005-10-21 2012-05-01 Amgen Inc. CGRP peptide antagonists and conjugates
AU2007293885A1 (en) 2006-09-07 2008-03-13 Takeda Gmbh Combination treatment for diabetes mellitus
EP2120985B1 (en) 2007-02-05 2012-06-27 Amylin Pharmaceuticals, Inc. FN-38 peptides for use in the treatment of psychotic and anxiety disorders
JP2009149684A (ja) * 2009-03-11 2009-07-09 Amylin Pharmaceut Inc アミリン作動薬ペプチド用製剤
RU2537181C2 (ru) 2009-03-12 2014-12-27 Нордик Байосайенс А/С Лечение диабета и метаболического синдрома
AR097701A1 (es) * 2013-09-19 2016-04-13 Zealand Pharma As Análogos de amilina
JP6657101B2 (ja) 2013-11-05 2020-03-04 ベン グリオン ユニバーシティ オブ ザ ネガフ リサーチ アンド ディベロップメント オーソリティ 糖尿病及びそれから生じる疾患合併症の治療のための化合物
CA2947587C (en) * 2014-05-02 2022-10-18 The Research Foundation For The State University Of New York Islet amyloid polypeptides with improved solubility
MX2017011182A (es) * 2015-03-18 2018-06-06 Zealand Pharma As Analogos de amilina.
AR109514A1 (es) 2016-09-09 2018-12-19 Zealand Pharma As Análogos de amilina
US11028137B2 (en) 2017-02-01 2021-06-08 The Research Foundation For The State University Of New York Mutant islet amyloid polypeptides with improved solubility and methods for using the same
KR102130354B1 (ko) * 2019-08-14 2020-07-06 엘아이지넥스원 주식회사 코어 제거용 이형장치
IL312600A (en) 2022-05-30 2024-07-01 Zealand Pharma As Liquid formulations of amylin analogs
AU2023346836A1 (en) 2022-09-19 2025-03-20 Zealand Pharma A/S Combination therapy
WO2024261259A1 (en) 2023-06-21 2024-12-26 Zealand Pharma A/S Analogues with improved properties
WO2024261076A1 (en) 2023-06-21 2024-12-26 Zealand Pharma A/S Weight loss
WO2025003471A1 (en) 2023-06-30 2025-01-02 Zealand Pharma A/S Combination therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
WO1989006135A1 (en) * 1988-01-11 1989-07-13 Amylin Corporation Treatment of type 2 diabetes mellitus
WO1991000737A1 (en) * 1989-07-10 1991-01-24 Amylin Corporation Treatment of obesity and essential hypertension and related disorders
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
WO1992015317A1 (en) * 1991-03-08 1992-09-17 Amylin Pharmaceuticals, Inc. Synthetic preparation of amylin and amylin analogues

Also Published As

Publication number Publication date
EP0567626B1 (en) 2001-09-19
AU673147B2 (en) 1996-10-31
CA2100745A1 (en) 1993-05-20
JP2003238594A (ja) 2003-08-27
DE69232064D1 (de) 2001-10-25
DK0567626T3 (da) 2001-12-17
EP0567626A1 (en) 1993-11-03
JPH11152299A (ja) 1999-06-08
MD960317A (ro) 1998-05-31
ATE205854T1 (de) 2001-10-15
RU2130463C1 (ru) 1999-05-20
FI118601B (fi) 2008-01-15
WO1993010146A1 (en) 1993-05-27
JP4018116B2 (ja) 2007-12-05
NO324405B1 (no) 2007-10-08
NO932603D0 (no) 1993-07-19
AU1245697A (en) 1997-03-27
EP1162207A1 (en) 2001-12-12
GR3036794T3 (en) 2002-01-31
SK88793A3 (en) 1994-12-07
ES2161697T3 (es) 2001-12-16
AU3075392A (en) 1993-06-15
CZ288029B6 (cs) 2001-04-11
CA2100745C (en) 2007-07-31
JP2006213716A (ja) 2006-08-17
HK1041891A1 (zh) 2002-07-26
NO932603L (no) 1993-09-17
NO20073265L (no) 1993-09-17
DE69232064T2 (de) 2002-03-28
FI933252L (fi) 1993-08-23
JP2902115B2 (ja) 1999-06-07
JPH06504794A (ja) 1994-06-02
AU714439B2 (en) 2000-01-06
CZ168993A3 (en) 1994-04-13

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