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FI924427A0 - Bensylfosfonsyratyrosinkinas -inhibitorer. - Google Patents

Bensylfosfonsyratyrosinkinas -inhibitorer.

Info

Publication number
FI924427A0
FI924427A0 FI924427A FI924427A FI924427A0 FI 924427 A0 FI924427 A0 FI 924427A0 FI 924427 A FI924427 A FI 924427A FI 924427 A FI924427 A FI 924427A FI 924427 A0 FI924427 A0 FI 924427A0
Authority
FI
Finland
Prior art keywords
pct
sec
benzylphosphonyratyrosininkin
inhibitorer
tyrosine kinase
Prior art date
Application number
FI924427A
Other languages
English (en)
Finnish (fi)
Other versions
FI924427L (fi
Inventor
Robert Lee Dow
Steven Wayne Goldstein
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI924427L publication Critical patent/FI924427L/fi
Publication of FI924427A0 publication Critical patent/FI924427A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3882—Arylalkanephosphonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5537—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom the heteroring containing the structure -C(=O)-N-C(=O)- (both carbon atoms belong to the heteroring)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI924427A 1990-04-02 1992-10-01 Bensylfosfonsyratyrosinkinas -inhibitorer. FI924427A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50318890A 1990-04-02 1990-04-02
PCT/US1991/001731 WO1991015495A1 (en) 1990-04-02 1991-03-14 Benzylphosphonic acid tyrosine kinase inhibitors

Publications (2)

Publication Number Publication Date
FI924427L FI924427L (fi) 1992-10-01
FI924427A0 true FI924427A0 (fi) 1992-10-01

Family

ID=24001079

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924427A FI924427A0 (fi) 1990-04-02 1992-10-01 Bensylfosfonsyratyrosinkinas -inhibitorer.

Country Status (12)

Country Link
US (1) US5326905A (es)
EP (1) EP0526488B1 (es)
JP (1) JPH0662650B2 (es)
AT (1) ATE114661T1 (es)
CA (1) CA2078214C (es)
DE (1) DE69105495T2 (es)
DK (1) DK0526488T3 (es)
ES (1) ES2064101T3 (es)
FI (1) FI924427A0 (es)
IE (1) IE64067B1 (es)
PT (1) PT97214A (es)
WO (1) WO1991015495A1 (es)

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Also Published As

Publication number Publication date
PT97214A (pt) 1992-01-31
ES2064101T3 (es) 1995-01-16
EP0526488B1 (en) 1994-11-30
DE69105495D1 (en) 1995-01-12
WO1991015495A1 (en) 1991-10-17
JPH0662650B2 (ja) 1994-08-17
FI924427L (fi) 1992-10-01
US5326905A (en) 1994-07-05
EP0526488A1 (en) 1993-02-10
CA2078214C (en) 1995-03-28
ATE114661T1 (de) 1994-12-15
JPH05502452A (ja) 1993-04-28
DK0526488T3 (da) 1995-04-24
IE911035A1 (en) 1991-10-09
DE69105495T2 (de) 1995-04-06
IE64067B1 (en) 1995-07-12

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