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FI924210L - Framstaellning av kristallin penem - Google Patents

Framstaellning av kristallin penem Download PDF

Info

Publication number
FI924210L
FI924210L FI924210A FI924210A FI924210L FI 924210 L FI924210 L FI 924210L FI 924210 A FI924210 A FI 924210A FI 924210 A FI924210 A FI 924210A FI 924210 L FI924210 L FI 924210L
Authority
FI
Finland
Prior art keywords
kristallin
penem
framstaellning
kristallin penem
Prior art date
Application number
FI924210A
Other languages
English (en)
Finnish (fi)
Other versions
FI924210A0 (fi
Inventor
Masayoshi Kaneko
Shigeo Yabuno
Original Assignee
Lederle Japan Ltd
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lederle Japan Ltd, Takeda Chemical Industries Ltd filed Critical Lederle Japan Ltd
Publication of FI924210A0 publication Critical patent/FI924210A0/fi
Publication of FI924210L publication Critical patent/FI924210L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI924210A 1991-09-20 1992-09-18 Framstaellning av kristallin penem FI924210L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24164891 1991-09-20

Publications (2)

Publication Number Publication Date
FI924210A0 FI924210A0 (fi) 1992-09-18
FI924210L true FI924210L (fi) 1993-03-21

Family

ID=17077445

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924210A FI924210L (fi) 1991-09-20 1992-09-18 Framstaellning av kristallin penem

Country Status (9)

Country Link
US (2) US5286856A (fr)
EP (1) EP0533149A1 (fr)
JP (1) JP2767171B2 (fr)
KR (1) KR930006022A (fr)
FI (1) FI924210L (fr)
IL (1) IL103218A0 (fr)
NO (2) NO923619L (fr)
TW (1) TW264475B (fr)
ZA (1) ZA927164B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW264475B (fr) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
US6111098A (en) * 1994-05-02 2000-08-29 Shionogi & Co., Ltd. Crystal of pyrrolidylthiocarbapenem derivative, lyophilized preparation containing said crystal, and process for producing the same
JP3953274B2 (ja) * 1998-03-02 2007-08-08 メルク エンド カムパニー インコーポレーテッド カルバペネム抗生物質の合成方法
DE10300620B4 (de) * 2002-05-18 2017-04-13 Carl Zeiss Meditec Ag Trägervorrichtung für ein medizinisch-optisches Gerät
KR101013535B1 (ko) * 2004-10-21 2011-02-14 주식회사 만도 자동차의 파워 스티어링 장치용 실린더 튜브와 피드튜브의 조립 구조물
HUE028503T2 (en) 2006-09-25 2016-12-28 Ptc Therapeutics Inc Crystalline Forms of 3- [5- (2-Fluorophenyl) - [1,2,4] oxadiazol-3-yl] benzoic acid
WO2009047604A1 (fr) * 2007-10-08 2009-04-16 Orchid Chemicals & Pharmaceuticals Limited Procédé de préparation de l'antibiotique carbapénème
DE102008043318A1 (de) 2008-10-30 2010-05-12 Mvg Metallverarbeitungsgesellschaft Mbh Anhängekupplung
WO2013132422A1 (fr) * 2012-03-05 2013-09-12 Orchid Chemicals & Pharmaceuticals Ltd Procédé amélioré pour la préparation d'un antibiotique carbapenem
PL2857401T3 (pl) 2012-05-30 2020-02-28 Meiji Seika Pharma Co., Ltd. NOWY INHIBITOR ß–LAKTAMAZY I SPOSÓB JEGO WYTWARZANIA
WO2014097221A1 (fr) 2012-12-21 2014-06-26 Ranbaxy Laboratories Limited Procédé pour la purification de biapenem
KR102239725B1 (ko) 2013-09-24 2021-04-12 메이지 세이카 파루마 가부시키가이샤 디아자비시클로옥탄 유도체의 제조법과 그의 중간체
AR097971A1 (es) 2013-10-08 2016-04-20 Meiji Seika Pharma Co Ltd Formas cristalinas de derivado de diazabiciclooctano y proceso de producción de ellas
EP3228620B1 (fr) 2014-12-05 2020-09-02 Meiji Seika Pharma Co., Ltd. Procédé pour la production de cristaux et d'une préparation lyophilisée stable d'un dérivé du diazabicyclooctane
CN114349772B (zh) * 2020-10-13 2022-11-25 珠海联邦制药股份有限公司 一种比阿培南粗品的精制方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration
IL53427A0 (en) * 1976-11-24 1978-01-31 Lilly Co Eli Method of preparing a rapidly dissolving powder of sterile crystalline cefozolin sodium for parenteral administration
JPS6024080B2 (ja) * 1977-06-01 1985-06-11 武田薬品工業株式会社 結晶の製造法
GB1589317A (en) * 1977-11-24 1981-05-13 Lilly Co Eli Freeze drying cephalothin sodium
JPS56120615A (en) * 1980-02-27 1981-09-22 Nippon Chemiphar Co Ltd Preparation of lyophilized powder of cephalothin
US4713451A (en) * 1984-04-09 1987-12-15 Merck & Co., Inc. Crystalline dimethyliminothienamycin
IE60588B1 (en) * 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
JPS6425779A (en) * 1987-04-11 1989-01-27 Lederle Japan Ltd (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative
US4866171A (en) * 1987-04-11 1989-09-12 Lederle (Japan), Ltd. (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium-6-yl)]thio-6-[R-1-hydroxyethyl]-1-methyl-carbapenum-3-carboxylate
DK168047B1 (da) * 1987-12-07 1994-01-24 Lederle Japan Ltd (1r,5s,6s)-2-substitueret thio-6-oe(r)-1-hydroxyethylaa-1-methyl-carbapenem-3-carboxylsyrederivater, fremgangsmaade til remstilling deraf, midler og praeparater indeholdende den krystallinske forbindelse samt dens anvendelse.
US5082661A (en) * 1990-09-26 1992-01-21 Elizabeth Arden Co., Division Of Conopco, Inc. Odorless cosmetic compositions in gelatin capsules
GB9021061D0 (en) * 1990-09-27 1990-11-07 Unilever Plc Encapsulating method and products containing encapsulated material
TW264475B (fr) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
SG49234A1 (en) * 1993-01-29 1998-05-18 Agouron Pharma Condensed heterocyclic glutamic acid derivatives as antiproliferative agents

Also Published As

Publication number Publication date
JP2767171B2 (ja) 1998-06-18
JPH05271241A (ja) 1993-10-19
EP0533149A1 (fr) 1993-03-24
NO923619L (no) 1993-03-22
NO923619D0 (no) 1992-09-17
ZA927164B (en) 1994-03-18
KR930006022A (ko) 1993-04-20
AU645442B2 (en) 1994-01-13
FI924210A0 (fi) 1992-09-18
NO971332D0 (no) 1997-03-21
US5286856A (en) 1994-02-15
US5424069A (en) 1995-06-13
TW264475B (fr) 1995-12-01
NO971332L (no) 1993-03-22
IL103218A0 (en) 1993-02-21
AU2459792A (en) 1993-03-25

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Legal Events

Date Code Title Description
FD Application lapsed