FI922592A0 - (arylalkylpiperidin-4-yl)metyl)-2a,3, 4,5-tetra-hydro-1(2h)-acetnaftylen-1-oner och motsvarande foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. - Google Patents
(arylalkylpiperidin-4-yl)metyl)-2a,3, 4,5-tetra-hydro-1(2h)-acetnaftylen-1-oner och motsvarande foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.Info
- Publication number
- FI922592A0 FI922592A0 FI922592A FI922592A FI922592A0 FI 922592 A0 FI922592 A0 FI 922592A0 FI 922592 A FI922592 A FI 922592A FI 922592 A FI922592 A FI 922592A FI 922592 A0 FI922592 A0 FI 922592A0
- Authority
- FI
- Finland
- Prior art keywords
- arylalkylpiperidin
- acetnaftylene
- oner
- hydro
- tetra
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Lubricants (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/713,249 US5106856A (en) | 1991-06-07 | 1991-06-07 | [(Arylalkylpiperidin-4-yl)methyl]-2a,3,4,5-tetrahydro-1(2H)-acenaphthylen-1-ones and related compounds |
| US71324991 | 1991-06-07 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI922592A0 true FI922592A0 (fi) | 1992-06-04 |
| FI922592A FI922592A (fi) | 1992-12-08 |
| FI101297B1 FI101297B1 (fi) | 1998-05-29 |
| FI101297B FI101297B (fi) | 1998-05-29 |
Family
ID=24865395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI922592A FI101297B (fi) | 1991-06-07 | 1992-06-04 | Menetelmä terapeuttisesti käyttökelpoisten £(N-bentsyylipiperidin-4-yy li)metyyli|-(tetra- tai heksahydro)asetnaftylen-1-onien tai -olien val mistamiseksi |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5106856A (fi) |
| EP (1) | EP0517221B1 (fi) |
| JP (1) | JP2961013B2 (fi) |
| KR (1) | KR100234445B1 (fi) |
| AT (1) | ATE131814T1 (fi) |
| AU (1) | AU646784B2 (fi) |
| CA (1) | CA2070714A1 (fi) |
| CZ (1) | CZ284591B6 (fi) |
| DE (1) | DE69206889T2 (fi) |
| DK (1) | DK0517221T3 (fi) |
| ES (1) | ES2081517T3 (fi) |
| FI (1) | FI101297B (fi) |
| GR (1) | GR3018558T3 (fi) |
| HU (1) | HU217967B (fi) |
| IE (1) | IE72199B1 (fi) |
| IL (1) | IL102118A (fi) |
| MX (1) | MX9202736A (fi) |
| NO (1) | NO178889C (fi) |
| NZ (1) | NZ243013A (fi) |
| PL (1) | PL169423B1 (fi) |
| RU (1) | RU2043989C1 (fi) |
| TW (1) | TW206214B (fi) |
| ZA (1) | ZA924109B (fi) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW248556B (fi) * | 1993-01-18 | 1995-06-01 | Takeda Pharm Industry Co | |
| US6939879B2 (en) * | 1998-08-28 | 2005-09-06 | Aventis Pharmaceuticals Inc. | Use of R (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol for the treatment of substance induced insomnia |
| NZ510685A (en) | 1998-09-30 | 2003-10-31 | Takeda Chemical Industries Ltd | Drugs for improving vesical excretory strength |
| CA2789014C (en) | 2010-02-09 | 2019-01-15 | Michela Gallagher | Methods and compositions for improving cognitive function |
| NO3034079T3 (fi) | 2010-11-15 | 2018-06-09 | ||
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| US11160785B2 (en) | 2013-03-15 | 2021-11-02 | Agenebio Inc. | Methods and compositions for improving cognitive function |
| EP2968237A4 (en) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION |
| CA2934553C (en) | 2013-12-20 | 2023-10-31 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| EA034167B8 (ru) | 2015-05-22 | 2021-04-27 | Эйджинбайо, Инк. | Фармацевтические композиции леветирацетама пролонгированного высвобождения |
| US10815242B2 (en) | 2015-06-19 | 2020-10-27 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US20180170941A1 (en) | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| BR112020026062B1 (pt) | 2018-06-19 | 2023-04-04 | Agenebio, Inc | Compostos derivados de benzodiazepina ou um sal farmaceuticamente aceitavel, isômero ou combinação dos mesmos, composição farmacêutica compreendendo os mesmos e usos dos mesmos para o tratamento de comprometimento cognitivo, câncer cerebral e psicose da doença de parkinson |
| US20240132513A1 (en) | 2022-08-19 | 2024-04-25 | Agenebio, Inc. | Benzazepine derivatives, compositions, and methods for treating cognitive impairment |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2589934A (en) * | 1950-08-24 | 1952-03-18 | Abbott Lab | 2-aminomethyl-tetrahydroacenapthones-1 and their preparation |
| US3391178A (en) * | 1964-12-30 | 1968-07-02 | Ernest E. Campaigne | Dialkylaminoalkyl 1-oxo-2alpha, 3, 4, 5-tetrahydroacenaphthen-2alpha-carboxylates |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| JP2969359B2 (ja) * | 1989-01-13 | 1999-11-02 | 武田薬品工業株式会社 | 環状アミン化合物 |
-
1991
- 1991-06-07 US US07/713,249 patent/US5106856A/en not_active Expired - Fee Related
-
1992
- 1992-05-23 TW TW081104034A patent/TW206214B/zh active
- 1992-06-04 EP EP92109467A patent/EP0517221B1/en not_active Expired - Lifetime
- 1992-06-04 FI FI922592A patent/FI101297B/fi not_active IP Right Cessation
- 1992-06-04 AT AT92109467T patent/ATE131814T1/de not_active IP Right Cessation
- 1992-06-04 DK DK92109467.8T patent/DK0517221T3/da active
- 1992-06-04 DE DE69206889T patent/DE69206889T2/de not_active Expired - Fee Related
- 1992-06-04 NZ NZ243013A patent/NZ243013A/en unknown
- 1992-06-04 ES ES92109467T patent/ES2081517T3/es not_active Expired - Lifetime
- 1992-06-05 HU HU9201887A patent/HU217967B/hu not_active IP Right Cessation
- 1992-06-05 KR KR1019920009765A patent/KR100234445B1/ko not_active IP Right Cessation
- 1992-06-05 ZA ZA924109A patent/ZA924109B/xx unknown
- 1992-06-05 PL PL92294803A patent/PL169423B1/pl unknown
- 1992-06-05 IL IL10211892A patent/IL102118A/en not_active IP Right Cessation
- 1992-06-05 JP JP4144694A patent/JP2961013B2/ja not_active Expired - Fee Related
- 1992-06-05 AU AU18015/92A patent/AU646784B2/en not_active Ceased
- 1992-06-05 NO NO922223A patent/NO178889C/no not_active IP Right Cessation
- 1992-06-05 CZ CS921713A patent/CZ284591B6/cs not_active IP Right Cessation
- 1992-06-06 RU SU925052251A patent/RU2043989C1/ru active
- 1992-06-08 MX MX9202736A patent/MX9202736A/es not_active IP Right Cessation
- 1992-06-08 CA CA002070714A patent/CA2070714A1/en not_active Abandoned
- 1992-07-01 IE IE921840A patent/IE72199B1/en not_active IP Right Cessation
-
1995
- 1995-12-28 GR GR950403690T patent/GR3018558T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Owner name: HOECHST MARION ROUSSEL, INC. |
|
| GB | Transfer or assigment of application |
Owner name: HOECHST MARION ROUSSEL, INC. |
|
| MA | Patent expired |