FI915653A - 5-amino-5,6,7,8-tetrahydroquinoliner och beslaektade foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. - Google Patents
5-amino-5,6,7,8-tetrahydroquinoliner och beslaektade foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. Download PDFInfo
- Publication number
- FI915653A FI915653A FI915653A FI915653A FI915653A FI 915653 A FI915653 A FI 915653A FI 915653 A FI915653 A FI 915653A FI 915653 A FI915653 A FI 915653A FI 915653 A FI915653 A FI 915653A
- Authority
- FI
- Finland
- Prior art keywords
- och
- arylalkyl
- alkyl
- formula
- deras
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 2
- ZMAFTVCNAYZLGF-UHFFFAOYSA-N 5,6,7,8-tetrahydroquinolin-5-amine Chemical class C1=CC=C2C(N)CCCC2=N1 ZMAFTVCNAYZLGF-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000007074 memory dysfunction Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 150000003530 tetrahydroquinolines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/620,811 US5110815A (en) | 1990-12-03 | 1990-12-03 | 5-amino-5,6,7,8-tetrahydroquinolines and related compounds and pharmaceutical use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI915653A0 FI915653A0 (fi) | 1991-11-29 |
| FI915653A true FI915653A (fi) | 1992-06-04 |
Family
ID=24487491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI915653A FI915653A (fi) | 1990-12-03 | 1991-11-29 | 5-amino-5,6,7,8-tetrahydroquinoliner och beslaektade foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US5110815A (xx) |
| EP (1) | EP0489379B1 (xx) |
| JP (1) | JP3090514B2 (xx) |
| KR (1) | KR100235506B1 (xx) |
| AT (1) | ATE168371T1 (xx) |
| AU (1) | AU639875B2 (xx) |
| CA (1) | CA2056793C (xx) |
| DE (1) | DE69129790T2 (xx) |
| DK (1) | DK0489379T3 (xx) |
| ES (1) | ES2119752T3 (xx) |
| FI (1) | FI915653A (xx) |
| IE (1) | IE914183A1 (xx) |
| NO (1) | NO914734L (xx) |
| NZ (1) | NZ240803A (xx) |
| PT (1) | PT99674B (xx) |
| TW (1) | TW211003B (xx) |
| ZA (1) | ZA919480B (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL112567A (en) * | 1994-02-10 | 2000-02-29 | Wyeth John & Brother Ltd | Substituted quinolines their preparation and pharmaceutical compositions containing them |
| IL112568A0 (en) * | 1994-02-10 | 1995-05-26 | Wyeth John & Brother Ltd | Substituted quinolines, their preparation and pharmaceutical compositions containing them |
| IL112566A (en) * | 1994-02-10 | 2000-10-31 | Wyeth John & Brother Ltd | Substituted quinolinones and pharmaceutical compositions containing them |
| KR0158065B1 (ko) * | 1995-05-29 | 1998-12-01 | 스기야마 가즈히코 | 반도체 집적회로장치 및 그 제조방법 |
| KR100648869B1 (ko) | 1998-09-30 | 2007-02-28 | 다케다 야쿠힌 고교 가부시키가이샤 | 방광 배출력 개선제 |
| TWI301760B (en) * | 2004-02-27 | 2008-10-11 | Merz Pharma Gmbh & Co Kgaa | Tetrahydroquinolinones and their use as antagonists of metabotropic glutamate receptors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4789678A (en) * | 1986-08-25 | 1988-12-06 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds |
| US4942168A (en) * | 1987-07-13 | 1990-07-17 | Hoechst-Roussel Pharmaceuticals Inc. | Hydroxyquinoline amines, and method of enhancing memory in mammals |
| EP0361489A3 (en) * | 1988-09-30 | 1991-06-12 | Chugai Seiyaku Kabushiki Kaisha | Novel 3,4-diaminoquinoline and pyridine compounds |
| JPH0322011A (ja) * | 1989-06-19 | 1991-01-30 | Nec Corp | キーボード入力データ処理方式 |
-
1990
- 1990-12-03 US US07/620,811 patent/US5110815A/en not_active Expired - Lifetime
-
1991
- 1991-11-22 TW TW080109151A patent/TW211003B/zh active
- 1991-11-29 NZ NZ24080391A patent/NZ240803A/en unknown
- 1991-11-29 FI FI915653A patent/FI915653A/fi unknown
- 1991-12-02 CA CA002056793A patent/CA2056793C/en not_active Expired - Fee Related
- 1991-12-02 EP EP91120652A patent/EP0489379B1/en not_active Expired - Lifetime
- 1991-12-02 ES ES91120652T patent/ES2119752T3/es not_active Expired - Lifetime
- 1991-12-02 IE IE418391A patent/IE914183A1/en not_active IP Right Cessation
- 1991-12-02 AU AU88352/91A patent/AU639875B2/en not_active Expired - Fee Related
- 1991-12-02 JP JP03317805A patent/JP3090514B2/ja not_active Expired - Fee Related
- 1991-12-02 NO NO91914734A patent/NO914734L/no unknown
- 1991-12-02 DE DE69129790T patent/DE69129790T2/de not_active Expired - Fee Related
- 1991-12-02 DK DK91120652T patent/DK0489379T3/da active
- 1991-12-02 AT AT91120652T patent/ATE168371T1/de not_active IP Right Cessation
- 1991-12-02 ZA ZA919480A patent/ZA919480B/xx unknown
- 1991-12-03 KR KR1019910022011A patent/KR100235506B1/ko not_active IP Right Cessation
- 1991-12-03 PT PT99674A patent/PT99674B/pt not_active IP Right Cessation
-
1993
- 1993-03-19 US US08/035,335 patent/US5310914A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA919480B (en) | 1992-08-26 |
| US5110815A (en) | 1992-05-05 |
| DE69129790T2 (de) | 1999-05-06 |
| AU639875B2 (en) | 1993-08-05 |
| US5310914A (en) | 1994-05-10 |
| JPH04290872A (ja) | 1992-10-15 |
| NO914734D0 (no) | 1991-12-02 |
| KR100235506B1 (ko) | 1999-12-15 |
| NO914734L (no) | 1992-06-04 |
| DK0489379T3 (da) | 1999-04-19 |
| ES2119752T3 (es) | 1998-10-16 |
| CA2056793A1 (en) | 1992-06-04 |
| JP3090514B2 (ja) | 2000-09-25 |
| AU8835291A (en) | 1992-06-04 |
| IE914183A1 (en) | 1992-06-03 |
| NZ240803A (en) | 1994-07-26 |
| TW211003B (xx) | 1993-08-11 |
| FI915653A0 (fi) | 1991-11-29 |
| KR920012036A (ko) | 1992-07-25 |
| DE69129790D1 (de) | 1998-08-20 |
| EP0489379B1 (en) | 1998-07-15 |
| ATE168371T1 (de) | 1998-08-15 |
| PT99674A (pt) | 1992-10-30 |
| CA2056793C (en) | 2003-03-11 |
| EP0489379A1 (en) | 1992-06-10 |
| PT99674B (pt) | 1999-05-31 |
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