FI913502A - 1-(substituerade pyridinylamino-1h -indol-5-yl-substuerade karbamater, foerfarande och mellanprdukter foer framstaellning av dessa och deras anvaendning som laekemedel. - Google Patents

1-(substituerade pyridinylamino-1h -indol-5-yl-substuerade karbamater, foerfarande och mellanprdukter foer framstaellning av dessa och deras anvaendning som laekemedel. Download PDF

Info

Publication number: FI913502A
Authority: FI; Finland
Prior art keywords: loweralkyl; och; hydrogen; substituarade; mellanprdukter
Prior art date: 1990-07-23

Application number

FI913502A

Other languages

English (en)

Other versions

FI102067B1 (fi

FI102067B (fi

FI913502A0 (fi

Inventor

Richard Charles Effland

Larry Davis

Gordon Edward Olsen

Joseph Thomas Klein

David Gordon Wettlaufer

Peter Allen Nemoto

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-23

Filing date

1991-07-19

Publication date

1992-01-24

1991-07-19 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1991-07-19 Publication of FI913502A0 publication Critical patent/FI913502A0/fi

1992-01-24 Publication of FI913502A publication Critical patent/FI913502A/fi

1998-10-15 Application granted granted Critical

1998-10-15 Publication of FI102067B1 publication Critical patent/FI102067B1/fi

1998-10-15 Publication of FI102067B publication Critical patent/FI102067B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

FI913502A 1990-07-23 1991-07-19 Menetelmä terapeuttisesti käyttökelpoisten 1-(substituoitu pyridinyyli amino)-1H-indol-5-yyli-substituoitujen karbamaattien valmistamiseksi FI102067B (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/555,890 US5102891A (en)	1990-07-23	1990-07-23	1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates

Publications (4)

Publication Number	Publication Date
FI913502A0 FI913502A0 (fi)	1991-07-19
FI913502A true FI913502A (fi)	1992-01-24
FI102067B1 FI102067B1 (fi)	1998-10-15
FI102067B FI102067B (fi)	1998-10-15

Family

ID=24218998

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI913502A FI102067B (fi)	1990-07-23	1991-07-19	Menetelmä terapeuttisesti käyttökelpoisten 1-(substituoitu pyridinyyli amino)-1H-indol-5-yyli-substituoitujen karbamaattien valmistamiseksi

Country Status (23)

Country	Link
US (1)	US5102891A (fi)
EP (1)	EP0468401B1 (fi)
JP (1)	JP2564714B2 (fi)
KR (1)	KR100201515B1 (fi)
AT (1)	ATE171176T1 (fi)
AU (1)	AU639581B2 (fi)
BR (1)	BR1100534A (fi)
CA (1)	CA2047531C (fi)
CZ (1)	CZ283253B6 (fi)
DE (1)	DE69130196T2 (fi)
DK (1)	DK0468401T3 (fi)
ES (1)	ES2121761T3 (fi)
FI (1)	FI102067B (fi)
HU (1)	HUT58317A (fi)
IE (1)	IE912567A1 (fi)
IL (1)	IL98920A (fi)
MX (1)	MX9100342A (fi)
NO (1)	NO300132B1 (fi)
NZ (1)	NZ239038A (fi)
PL (1)	PL291185A1 (fi)
PT (1)	PT98413B (fi)
SG (1)	SG48059A1 (fi)
ZA (1)	ZA915723B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5264442A (en) *	1990-08-13	1993-11-23	Hoechst-Roussel Pharmaceuticals Incorporated	Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
CZ284437B6 (cs) *	1991-04-17	1998-11-11	Hoechst Marion Roussel, Inc.	Substituované (pyridinylamino)-benzisoxazoly a -benzo[b]thiofeny, způsob jejich přípravy farmaceutický prostředek obsahující tyto sloučeniny a použití těchto sloučenin
US5319096A (en) *	1992-04-03	1994-06-07	Hoechst-Roussel Pharmaceuticals Inc.	(1H-indol-1-yl)-2-(amino) acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, pharmaceutical composition and use
US5459274A (en) *	1994-05-13	1995-10-17	Hoechst-Roussel Pharmaceuticals Inc.	Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines
US6004977A (en) *	1996-12-27	1999-12-21	Hoechst Marion Roussel, Inc.	N-(pyridinylamino) isoindolines and related compounds
PT950056E (pt) *	1996-12-27	2002-12-31	Aventis Pharma Inc	N-(piridinilamino) isoindolinas e compostos relacionados
US6218383B1 (en)	1998-08-07	2001-04-17	Targacept, Inc.	Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
GT200500063A (es) *	2004-04-01	2005-10-14		Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias
FR2888238B1 (fr) *	2005-07-07	2007-09-07	Servier Lab	Nouveaux derives 1h-indole-pyridinecarboxamides et 1h-indole-piperidinecarboxamide, leur procede de preparation et les compositions pharceumatiques qui les contiennent.
CA2789014C (en)	2010-02-09	2019-01-15	Michela Gallagher	Methods and compositions for improving cognitive function
US20140206667A1 (en)	2012-11-14	2014-07-24	Michela Gallagher	Methods and compositions for treating schizophrenia
US11160785B2 (en)	2013-03-15	2021-11-02	Agenebio Inc.	Methods and compositions for improving cognitive function
EP2968237A4 (en)	2013-03-15	2016-08-31	Univ Johns Hopkins	METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
EA034167B8 (ru)	2015-05-22	2021-04-27	Эйджинбайо, Инк.	Фармацевтические композиции леветирацетама пролонгированного высвобождения

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4791107A (en) *	1986-07-16	1988-12-13	Hoechst-Roussel Pharmaceuticals, Inc.	Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
ES2065324T3 (es) *	1987-04-24	1995-02-16	Hoechst Roussel Pharma	N-(piridinil)-1h-indol-1-aminas, un procedimiento para su preparacion y su uso como medicamentos.
US4970218A (en) *	1987-04-24	1990-11-13	Hoechst-Roussel Pharmaceuticals Inc.	N-(pyridinyl)-1H-indol-1-amines
US4983615A (en) *	1989-06-28	1991-01-08	Hoechst-Roussel Pharmaceuticals Inc.	Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders
US5006537A (en) *	1989-08-02	1991-04-09	Hoechst-Roussel Pharmaceuticals, Inc.	1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones
US4992448A (en) *	1989-10-24	1991-02-12	Hoechst-Roussel Pharmaceuticals Inc.	Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders

1990
- 1990-07-23 US US07/555,890 patent/US5102891A/en not_active Expired - Fee Related
1991
- 1991-07-19 NZ NZ239038A patent/NZ239038A/en unknown
- 1991-07-19 FI FI913502A patent/FI102067B/fi active IP Right Grant
- 1991-07-22 ZA ZA915723A patent/ZA915723B/xx unknown
- 1991-07-22 DK DK91112237T patent/DK0468401T3/da active
- 1991-07-22 PT PT98413A patent/PT98413B/pt not_active IP Right Cessation
- 1991-07-22 ES ES91112237T patent/ES2121761T3/es not_active Expired - Lifetime
- 1991-07-22 PL PL29118591A patent/PL291185A1/xx unknown
- 1991-07-22 IL IL9892091A patent/IL98920A/en not_active IP Right Cessation
- 1991-07-22 JP JP3181210A patent/JP2564714B2/ja not_active Expired - Fee Related
- 1991-07-22 IE IE256791A patent/IE912567A1/en not_active IP Right Cessation
- 1991-07-22 SG SG1996006744A patent/SG48059A1/en unknown
- 1991-07-22 NO NO912866A patent/NO300132B1/no unknown
- 1991-07-22 DE DE69130196T patent/DE69130196T2/de not_active Expired - Fee Related
- 1991-07-22 AT AT91112237T patent/ATE171176T1/de not_active IP Right Cessation
- 1991-07-22 CA CA002047531A patent/CA2047531C/en not_active Expired - Fee Related
- 1991-07-22 HU HU912450A patent/HUT58317A/hu unknown
- 1991-07-22 EP EP91112237A patent/EP0468401B1/en not_active Expired - Lifetime
- 1991-07-22 AU AU81216/91A patent/AU639581B2/en not_active Expired - Fee Related
- 1991-07-22 CZ CS912281A patent/CZ283253B6/cs not_active IP Right Cessation
- 1991-07-23 KR KR1019910012579A patent/KR100201515B1/ko not_active IP Right Cessation
- 1991-07-23 MX MX9100342A patent/MX9100342A/es not_active IP Right Cessation
1997
- 1997-04-13 BR BR1100534-3A patent/BR1100534A/pt active IP Right Grant

Also Published As

Publication number	Publication date
KR920002585A (ko)	1992-02-28
US5102891A (en)	1992-04-07
NO912866D0 (no)	1991-07-22
DE69130196T2 (de)	1999-04-01
ES2121761T3 (es)	1998-12-16
NO912866L (no)	1992-01-24
IE912567A1 (en)	1992-01-29
AU8121691A (en)	1992-01-30
ATE171176T1 (de)	1998-10-15
PT98413A (pt)	1992-05-29
FI102067B1 (fi)	1998-10-15
DE69130196D1 (de)	1998-10-22
FI102067B (fi)	1998-10-15
JP2564714B2 (ja)	1996-12-18
EP0468401A3 (en)	1992-07-29
CZ283253B6 (cs)	1998-02-18
ZA915723B (en)	1992-04-29
EP0468401A2 (en)	1992-01-29
HUT58317A (en)	1992-02-28
EP0468401B1 (en)	1998-09-16
CA2047531C (en)	2003-01-07
FI913502A0 (fi)	1991-07-19
PL291185A1 (en)	1993-04-05
MX9100342A (es)	1992-02-28
HU912450D0 (en)	1991-12-30
AU639581B2 (en)	1993-07-29
DK0468401T3 (da)	1999-06-14
JPH04243878A (ja)	1992-08-31
CS228191A3 (en)	1992-02-19
BR1100534A (pt)	2000-03-14
SG48059A1 (en)	1998-04-17
NO300132B1 (no)	1997-04-14
CA2047531A1 (en)	1992-01-24
IL98920A (en)	1995-08-31
NZ239038A (en)	1994-04-27
PT98413B (pt)	1999-01-29
KR100201515B1 (ko)	1999-06-15

Publication	Publication Date	Title
FI913502A (fi)	1992-01-24	1-(substituerade pyridinylamino-1h -indol-5-yl-substuerade karbamater, foerfarande och mellanprdukter foer framstaellning av dessa och deras anvaendning som laekemedel.
ES2079530T3 (es)	1996-01-16	1-(piridinilalquil)-1h-indoles, -indolinas y compuestos analogos relacionados.
NO902556D0 (no)	1990-06-08	4,5,5a,6-tetrahydro-3h-isoksazol(5,4,3-kl)akridinderivater og fremgangsmaate for fremstilling derav.
FI913801A0 (fi)	1991-08-09	Karbamoyl-1-(pyridinylalkyl)-1h -indoler, indoliner och relaterade analoger.

Legal Events

Date	Code	Title	Description
1991-07-19	FG	Patent granted	Owner name: HOECHST MARION ROUSSEL, INC.
1997-06-13	GB	Transfer or assigment of application	Owner name: HOECHST MARION ROUSSEL, INC.