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FI906273L - Foereningar foer behandling av inflammatorisk tarmsjukdom. - Google Patents

Foereningar foer behandling av inflammatorisk tarmsjukdom. Download PDF

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Publication number
FI906273L
FI906273L FI906273A FI906273A FI906273L FI 906273 L FI906273 L FI 906273L FI 906273 A FI906273 A FI 906273A FI 906273 A FI906273 A FI 906273A FI 906273 L FI906273 L FI 906273L
Authority
FI
Finland
Prior art keywords
tharmsjukdom
inflammatorisk
foereningar
foer behandling
behandling
Prior art date
Application number
FI906273A
Other languages
English (en)
Other versions
FI104251B (fi
FI906273A0 (fi
FI104251B1 (fi
Inventor
Jaswant Singh Gidda
Jill Ann Panetta
Michael Leroy Phillips
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI906273A0 publication Critical patent/FI906273A0/fi
Publication of FI906273L publication Critical patent/FI906273L/fi
Application granted granted Critical
Publication of FI104251B publication Critical patent/FI104251B/fi
Publication of FI104251B1 publication Critical patent/FI104251B1/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Surgical Instruments (AREA)
  • Nonmetallic Welding Materials (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Eye Examination Apparatus (AREA)
FI906273A 1989-12-21 1990-12-19 Menetelmä tulehduksellisten suolistosairauksien hoitoon käyttökelpoisten yhdisteiden valmistamiseksi FI104251B1 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45420389A 1989-12-21 1989-12-21
US45420389 1989-12-21

Publications (4)

Publication Number Publication Date
FI906273A0 FI906273A0 (fi) 1990-12-19
FI906273L true FI906273L (fi) 1991-06-22
FI104251B FI104251B (fi) 1999-12-15
FI104251B1 FI104251B1 (fi) 1999-12-15

Family

ID=23803709

Family Applications (2)

Application Number Title Priority Date Filing Date
FI906273A FI104251B1 (fi) 1989-12-21 1990-12-19 Menetelmä tulehduksellisten suolistosairauksien hoitoon käyttökelpoisten yhdisteiden valmistamiseksi
FI991698A FI19991698L (fi) 1989-12-21 1999-08-10 Menetelmä selektiivisesti eristää, oleellisesti puhtaassa enantiomeerisessä muodossa, raseemisten bentsyylisubstituoitujen rodaniinijohdannaisten enantiomeerejä

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI991698A FI19991698L (fi) 1989-12-21 1999-08-10 Menetelmä selektiivisesti eristää, oleellisesti puhtaassa enantiomeerisessä muodossa, raseemisten bentsyylisubstituoitujen rodaniinijohdannaisten enantiomeerejä

Country Status (22)

Country Link
EP (1) EP0434394B1 (fi)
JP (1) JP3036853B2 (fi)
KR (1) KR0176243B1 (fi)
CN (1) CN1029846C (fi)
AT (1) ATE169294T1 (fi)
AU (1) AU639734B2 (fi)
CA (1) CA2032330C (fi)
CY (1) CY2100B1 (fi)
DE (1) DE69032537T2 (fi)
DK (1) DK0434394T3 (fi)
ES (1) ES2121748T3 (fi)
FI (2) FI104251B1 (fi)
HU (1) HU216732B (fi)
IE (1) IE904633A1 (fi)
IL (3) IL108962A (fi)
MX (1) MX23803A (fi)
NO (1) NO300458B1 (fi)
NZ (1) NZ236472A (fi)
PT (1) PT96198B (fi)
RU (2) RU2036915C1 (fi)
YU (1) YU240690A (fi)
ZA (1) ZA9010041B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU87339A1 (fr) * 1988-09-20 1990-04-06 Oreal Nouveaux derives de benzylidene-cyclanones,leur procede de preparation,leur utilisation en tant qu'agents anti-oxydants et comme filtres solaires,compositions cosmetiques et pharmaceutiques les contenant
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
IL106877A (en) * 1992-09-10 1998-03-10 Lilly Co Eli Rodinin derivatives for use as drugs for the treatment of Alzheimer's disease
DE69301894T2 (de) * 1992-10-28 1996-11-07 Shionogi & Co Benzylidenderivate
US6251928B1 (en) 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
US5563277A (en) * 1994-12-21 1996-10-08 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives
ES2153081T3 (es) * 1995-09-07 2001-02-16 Lilly Co Eli Forma cristalina alternativa de tazofelona((+,-)-5-((3,5-bis(1,1-dimetiletil)-4-hidroxifenil)metil)-4-tiazolidinona).
ATE193284T1 (de) * 1995-09-07 2000-06-15 Lilly Co Eli Verfahren zur herstellung von benzylsubstituierten rhodaninederivaten
EP0779282A1 (en) * 1995-12-14 1997-06-18 Eli Lilly And Company Thiomorpholinone compounds for treating multiple sclerosis
US5981523A (en) * 1996-02-05 1999-11-09 Eli Lilly And Company Compounds and methods for treating multiple sclerosis
US6063799A (en) * 1996-09-03 2000-05-16 Eli Lilly And Company Alternate crystal form of Tazofelone
US6005142A (en) 1996-09-03 1999-12-21 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives
WO2000018748A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Rhodanine derivatives for the treatment and prevention of metabolic bone disorders
WO2000018746A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Thiazolidine derivatives for the treatment and prevention of metabolic bone disorders
WO2000018747A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders
BR0314943A (pt) * 2002-09-30 2005-08-02 Univ California Inibidores da proteìna reguladora da condutância transmembrana da fibrose cìstica e usos destes
US7235573B2 (en) 2002-09-30 2007-06-26 The Regents Of The University Of California Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors
AU2002953533A0 (en) * 2002-12-24 2003-01-16 Arthron Limited Fc receptor modulating compounds and compositions
JP5778755B2 (ja) * 2010-04-15 2015-09-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung ヒドロキノンの製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR862081B (en) * 1985-08-09 1986-12-24 Lilly Co Eli Di-t-butylphenol compounds
IE940525L (en) * 1988-05-25 1989-11-25 Warner Lambert Co Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents
CA2013599C (en) * 1989-04-07 1999-11-16 Jill A. Panetta Aryl-substituted rhodanine derivatives

Also Published As

Publication number Publication date
FI104251B (fi) 1999-12-15
NO905478D0 (no) 1990-12-19
AU639734B2 (en) 1993-08-05
IL96654A (en) 1995-06-29
CY2100B1 (en) 2002-04-05
HU908368D0 (en) 1991-07-29
ZA9010041B (en) 1992-08-26
IL108962A0 (en) 1994-06-24
FI19991698L (fi) 1999-08-10
EP0434394B1 (en) 1998-08-05
CN1052668A (zh) 1991-07-03
KR910011812A (ko) 1991-08-07
NO300458B1 (no) 1997-06-02
PT96198A (pt) 1991-09-30
IE904633A1 (en) 1991-07-17
FI906273A0 (fi) 1990-12-19
MX23803A (es) 1994-02-28
IL108962A (en) 1996-12-05
CA2032330C (en) 2001-05-08
EP0434394A3 (en) 1992-01-08
HUT59915A (en) 1992-07-28
CN1029846C (zh) 1995-09-27
AU6826690A (en) 1991-06-27
FI104251B1 (fi) 1999-12-15
JPH04279573A (ja) 1992-10-05
EP0434394A2 (en) 1991-06-26
DE69032537T2 (de) 1999-01-21
RU2050355C1 (ru) 1995-12-20
DE69032537D1 (de) 1998-09-10
HU216732B (hu) 1999-08-30
ES2121748T3 (es) 1998-12-16
DK0434394T3 (da) 1998-12-14
PT96198B (pt) 1998-05-29
RU2036915C1 (ru) 1995-06-09
YU240690A (sh) 1992-12-21
CA2032330A1 (en) 1991-06-22
KR0176243B1 (ko) 1999-03-20
NO905478L (no) 1991-06-24
ATE169294T1 (de) 1998-08-15
NZ236472A (en) 1993-03-26
JP3036853B2 (ja) 2000-04-24

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: ELI LILLY AND COMPANY