FI903108A0 - Paramagnetiska foereningar. - Google Patents

Paramagnetiska foereningar.

Info

Publication number: FI903108A0
Authority: FI; Finland
Prior art keywords: foereningar; paramagnetic; paramagnetic foereningar
Prior art date: 1988-01-26

Application number

FI903108A

Other languages

English (en)

Inventor

Jo Klaveness

Paol Rongved

Per Strande

Original Assignee

Nycomed As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-26

Filing date

1990-06-20

Publication date

1990-06-20

1990-06-20 Application filed by Nycomed As filed Critical Nycomed As

1990-06-20 Publication of FI903108A0 publication Critical patent/FI903108A0/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
- A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Radiology & Medical Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

FI903108A 1988-01-26 1990-06-20 Paramagnetiska foereningar. FI903108A0 (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB888801646A GB8801646D0 (en)	1988-01-26	1988-01-26	Chemical compounds
PCT/EP1989/000078 WO1989006979A1 (en)	1988-01-26	1989-01-26	Paramagnetic compounds

Publications (1)

Publication Number	Publication Date
FI903108A0 true FI903108A0 (fi)	1990-06-20

Family

ID=10630512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI903108A FI903108A0 (fi)	1988-01-26	1990-06-20	Paramagnetiska foereningar.

Country Status (13)

Country	Link
US (1)	US5208324A (fi)
EP (2)	EP0326226A1 (fi)
JP (1)	JPH03502338A (fi)
CA (1)	CA1331458C (fi)
DK (1)	DK175390A (fi)
FI (1)	FI903108A0 (fi)
GB (1)	GB8801646D0 (fi)
HU (1)	HU205212B (fi)
IE (1)	IE890233L (fi)
NZ (1)	NZ227750A (fi)
RU (1)	RU2081881C1 (fi)
WO (1)	WO1989006979A1 (fi)
ZA (1)	ZA89628B (fi)

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US5707604A (en) *	1986-11-18	1998-01-13	Access Pharmaceuticals, Inc.	Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
US5672334A (en) *	1991-01-16	1997-09-30	Access Pharmaceuticals, Inc.	Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans
GB8900719D0 (en) *	1989-01-13	1989-03-08	Nycomed As	Compounds
US5395608A (en) *	1989-04-26	1995-03-07	The Curators Of The University Of Missouri	Triamine chelants, their derivatives, complexes and conjugates
AU6709390A (en) *	1989-12-22	1991-06-27	E.R. Squibb & Sons, Inc.	10-(2'-hydroxy-3'-polyoxaalkyl)-1,4,7-tris-carboxymethyl -1,4,7,10-tetraazacyclododecane
AU625529B2 (en) *	1989-12-22	1992-07-16	E.R. Squibb & Sons, Inc.	10-(2'-hydroxy-3'-alkoxy-1,4,7-triscarboxymethyl-1,4,7,10- tetraazacyclododecanes
WO1991010669A1 (en) *	1990-01-19	1991-07-25	Cockbain, Julian, Roderick, Michaelson	Chelating compounds
US5236694A (en) *	1990-02-21	1993-08-17	The Board Of Regents, The University Of Texas System	19f labelled dextrans and antibodies as nmr imaging and spectroscopy agents
US5190744A (en) *	1990-03-09	1993-03-02	Salutar	Methods for detecting blood perfusion variations by magnetic resonance imaging
US5494655A (en) *	1990-03-09	1996-02-27	The Regents Of The University Of California	Methods for detecting blood perfusion variations by magnetic resonance imaging
FR2663544B1 (fr) *	1990-06-26	1994-05-06	Medgenix Group Sa	Agent de contraste pour l'imagerie par rmn et agents chelateurs comportant des structures peptidiques.
US5370901A (en) *	1991-02-15	1994-12-06	Bracco International B.V.	Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients
EP0598837A4 (en) *	1991-08-09	1994-07-13	Univ California	Amino acid, ester and/or catechol contrast agents for mri.
US5562894A (en) *	1991-08-09	1996-10-08	Regents Of The University Of California	Amino-acyl-type and catecholamine-type contrast agents for MRI
CA2092596A1 (en) *	1992-03-27	1993-09-28	Kan Kubomura	Tetraazacyclododecane derivative and its use
US5514379A (en) *	1992-08-07	1996-05-07	The General Hospital Corporation	Hydrogel compositions and methods of use
EP0665729B1 (en) *	1992-09-04	2003-05-07	The General Hospital Corporation	Biocompatible polymers containing diagnostic or therapeutic moieties
US5871710A (en) *	1992-09-04	1999-02-16	The General Hospital Corporation	Graft co-polymer adducts of platinum (II) compounds
US5817292A (en) *	1992-10-14	1998-10-06	Nycomed Imaging As	MR imaging compositions and methods
US5756688A (en) *	1992-10-14	1998-05-26	Sterling Winthrop Inc.	MR imaging compositions and methods
US5401493A (en) *	1993-03-26	1995-03-28	Molecular Biosystems, Inc.	Perfluoro-1H,-1H-neopentyl containing contrast agents and method to use same
WO1994027498A1 (en) *	1993-05-20	1994-12-08	The Regents Of The University Of California	Macromolecular contrast media for mr imaging
US5605672A (en) *	1993-06-09	1997-02-25	The General Hospital Corporation	Blood pool imaging composition and method of its use
JP3320734B2 (ja) *	1993-07-28	2002-09-03	ダイアタイド・インコーポレイテッド	放射性同位体標識したグルカン類
US5730968A (en) *	1994-03-31	1998-03-24	Sterling Winthrop Inc.	Segmented chelating polymers as imaging and therapeutic agents
FI954967A (fi) *	1994-10-21	1996-04-22	Nihon Mediphysics Co Ltd	Diagnostinen kuvausaine
US5602180A (en) *	1995-03-31	1997-02-11	World Health Group	Method of administering EDTA complexes
US6106866A (en) *	1995-07-31	2000-08-22	Access Pharmaceuticals, Inc.	In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
US6107090A (en)	1996-05-06	2000-08-22	Cornell Research Foundation, Inc.	Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
US6136311A (en) *	1996-05-06	2000-10-24	Cornell Research Foundation, Inc.	Treatment and diagnosis of cancer
NL1003776C2 (nl) *	1996-08-09	1998-02-20	Cooperatie Cosun U A	Milieuvriendelijke complexanten voor zware metalen
US6045776A (en) *	1996-12-04	2000-04-04	Schering Aktiengesellschaft	Process for the production of metal-complex carboxylic acid amides
DE19808079A1 (de) *	1998-02-20	1999-08-26	Schering Ag	Hydroxyethylstärke-Konjugate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
EP1390069A1 (en) *	2001-05-30	2004-02-25	Cornell Research Foundation, Inc.	Endopeptidase/anti-psma antibody fusion proteins for treatment of cancer
US7666414B2 (en) *	2001-06-01	2010-02-23	Cornell Research Foundation, Inc.	Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen
US7514078B2 (en) *	2001-06-01	2009-04-07	Cornell Research Foundation, Inc.	Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies
IL158969A0 (en) *	2001-06-01	2004-05-12	Cornell Res Foundation Inc	Modified antibodies to prostate-specific membrane antigen and uses thereof
IL159422A0 (en)	2001-09-20	2004-06-01	Cornell Res Foundation Inc	Methods and compositions for treating or preventing skin disorders using binding agents specific for prostate-specific membrane antigen
US20040136998A1 (en) *	2002-10-30	2004-07-15	Bander Neil H.	Methods and compositions for treating or preventing insulin-related disorders using binding agents specific for prostate specific membrane antigen
WO2004063701A2 (en) *	2003-01-10	2004-07-29	Millennium Pharmaceuticals, Inc.	Methods of diagnosing and treating cancer
US20050202020A1 (en) *	2004-01-09	2005-09-15	Jeffrey Ross	Diagnosing and treating cancer
WO2005094882A1 (en) *	2004-03-03	2005-10-13	Millennium Pharmaceuticals, Inc.	Modified antibodies to prostate-specific membrane antigen and uses thereof
WO2006124726A2 (en)	2005-05-12	2006-11-23	The General Hospital Corporation	Novel biotinylated compositions
US20090258028A1 (en) *	2006-06-05	2009-10-15	Abbott Cardiovascular Systems Inc.	Methods Of Forming Coatings For Implantable Medical Devices For Controlled Release Of A Peptide And A Hydrophobic Drug
US8323676B2 (en) *	2008-06-30	2012-12-04	Abbott Cardiovascular Systems Inc.	Poly(ester-amide) and poly(amide) coatings for implantable medical devices for controlled release of a protein or peptide and a hydrophobic drug
DE102007002726A1 (de)	2007-01-18	2008-07-31	Bayer Schering Pharma Aktiengesellschaft	Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US8765162B2 (en)	2008-06-30	2014-07-01	Abbott Cardiovascular Systems Inc.	Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same
US20100196272A1 (en) *	2009-01-30	2010-08-05	Neoprobe Corporation	Compositions for radiolabeling diethylenetriaminepentaacetic acid (dtpa)-dextran
KR20140037208A (ko) *	2011-06-21	2014-03-26	이뮤노젠 아이엔씨	펩타이드 링커를 갖는 신규한 메이탄시노이드 유도체 및 이의 접합체
EP2890788A1 (en)	2012-08-31	2015-07-08	The General Hospital Corporation	Biotin complexes for treatment and diagnosis of alzheimer's disease
WO2018053460A1 (en) *	2016-09-19	2018-03-22	The Regents Of The University Of California	Paramagnetic polymers
US11590225B2 (en)	2016-12-08	2023-02-28	The Brigham And Women's Hospital, Inc.	Bismuth-gadolinium nanoparticles
WO2021189052A1 (en)	2020-03-20	2021-09-23	Robert Taub	Composition for radiation treatment of intracavitary or metastatic deposits of malignancy and method for treatment therewith
FR3116197A1 (fr) *	2020-11-19	2022-05-20	Nh Theraguix	Procédé de traitement de tumeurs par captation du cuivre et/ou du fer

Family Cites Families (24)

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Publication number	Priority date	Publication date	Assignee	Title
SE420565B (sv) *	1974-06-06	1981-10-19	Pharmacia Ab	Hjelpmedel for intravaskuler administraring for anvendning i samband med intravaskuler administrering av en losning eller en suspension av ett diagnostiseringsmedel
DE3129906C3 (de) *	1981-07-24	1996-12-19	Schering Ag	Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
US4741900A (en) *	1982-11-16	1988-05-03	Cytogen Corporation	Antibody-metal ion complexes
NL194579C (nl) *	1983-01-21	2002-08-05	Schering Ag	Diagnostisch middel.
DE3324235A1 (de) *	1983-07-01	1985-01-10	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue komplexbildner, komplexe und komplexsalze
CA1243602A (en) *	1983-08-25	1988-10-25	Hong-Ning Yeung	Methods for enhancing the contrast in nmr imaging
US4615879A (en) *	1983-11-14	1986-10-07	Vanderbilt University	Particulate NMR contrast agents for gastrointestinal application
GB8413772D0 (en) *	1984-05-30	1984-07-04	Nyegaard & Co As	Chemical compounds
GB8413849D0 (en) *	1984-05-31	1984-07-04	Amersham Int Plc	Nmr contrast agents
US4687659A (en) *	1984-11-13	1987-08-18	Salutar, Inc.	Diamide-DTPA-paramagnetic contrast agents for MR imaging
US4687658A (en) *	1984-10-04	1987-08-18	Salutar, Inc.	Metal chelates of diethylenetriaminepentaacetic acid partial esters for NMR imaging
US4639365A (en) *	1984-10-18	1987-01-27	The Board Of Regents, The University Of Texas System	Gadolinium chelates as NMR contrast agents
SE465907B (sv) *	1984-11-01	1991-11-18	Nyegaard & Co As	Diagnosticeringsmedel innehaallande en paramagnetisk metall
EP0184899B1 (en) *	1984-11-01	1990-04-18	Nycomed As	Paramagnetic contrast agents for use in "in vivo" diagnostic methods using nmr, and their preparation
GB8522535D0 (en) *	1985-09-11	1985-10-16	Amersham Int Plc	Contrast agent
WO1987002893A1 (en) *	1985-11-18	1987-05-21	Board Of Regents, The University Of Texas System	Polychelating agents for image and spectral enhancement (and spectral shift)
US4885363A (en) *	1987-04-24	1989-12-05	E. R. Squibb & Sons, Inc.	1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
DE3772785D1 (de) *	1986-01-23	1991-10-17	Squibb & Sons Inc	1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga.
IT1213029B (it) *	1986-01-30	1989-12-07	Bracco Ind Chimica Spa	Chelati di ioni metallici paramagnetici.
US4699784A (en) *	1986-02-25	1987-10-13	Center For Molecular Medicine & Immunology	Tumoricidal methotrexate-antibody conjugate
US5057313A (en) *	1986-02-25	1991-10-15	The Center For Molecular Medicine And Immunology	Diagnostic and therapeutic antibody conjugates
FR2614020B1 (fr) *	1987-04-14	1989-07-28	Guerbet Sa	Nouveaux ligands cycliques azotes, complexes metalliques formes par ces ligands, compositions de diagnostic contenant ces complexes et procede de preparation des ligands.
EP0466200B1 (en) *	1987-07-16	1996-04-24	Nycomed Imaging As	Aminocarboxylic acids and derivatives thereof
US5047227A (en) *	1988-02-08	1991-09-10	Cytogen Corporation	Novel and improved antibodies for site specific attachment of compounds

1988
- 1988-01-26 GB GB888801646A patent/GB8801646D0/en active Pending
1989
- 1989-01-26 US US07/548,994 patent/US5208324A/en not_active Expired - Lifetime
- 1989-01-26 ZA ZA89628A patent/ZA89628B/xx unknown
- 1989-01-26 RU SU894830652A patent/RU2081881C1/ru active
- 1989-01-26 HU HU891057A patent/HU205212B/hu not_active IP Right Cessation
- 1989-01-26 WO PCT/EP1989/000078 patent/WO1989006979A1/en active IP Right Grant
- 1989-01-26 JP JP1501713A patent/JPH03502338A/ja active Pending
- 1989-01-26 IE IE890233A patent/IE890233L/xx unknown
- 1989-01-26 NZ NZ227750A patent/NZ227750A/en unknown
- 1989-01-26 CA CA000589198A patent/CA1331458C/en not_active Expired - Fee Related
- 1989-01-26 EP EP89200168A patent/EP0326226A1/en not_active Ceased
- 1989-01-26 EP EP89901948A patent/EP0396617B1/en not_active Expired - Lifetime
1990
- 1990-06-20 FI FI903108A patent/FI903108A0/fi not_active Application Discontinuation
- 1990-07-23 DK DK175390A patent/DK175390A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUT55022A (en)	1991-04-29
CA1331458C (en)	1994-08-16
ZA89628B (en)	1989-10-25
EP0396617B1 (en)	1992-06-24
RU2081881C1 (ru)	1997-06-20
JPH03502338A (ja)	1991-05-30
WO1989006979A1 (en)	1989-08-10
HU891057D0 (en)	1990-12-28
US5208324A (en)	1993-05-04
DK175390A (da)	1990-09-20
HU205212B (en)	1992-03-30
GB8801646D0 (en)	1988-02-24
EP0326226A1 (en)	1989-08-02
IE890233L (en)	1989-07-26
NZ227750A (en)	1991-03-26
DK175390D0 (da)	1990-07-23
EP0396617A1 (en)	1990-11-14

Publication	Publication Date	Title
FI903108A0 (fi)	1990-06-20	Paramagnetiska foereningar.
DE68906637D1 (de)	1993-06-24	Wafertraeger.
DE58905119D1 (de)	1993-09-09	Heteroaryloxyessigsaeure-n-isopropylanilide.
FI892342A (fi)	1989-12-05	Spontfoerbindning foer vaegg- eller takelement.
DE68921898D1 (de)	1995-04-27	Ringbinder.
FI904561A0 (fi)	1990-09-17	Modifierade hydrofila polyestrar.
DE58904437D1 (de)	1993-06-24	Rakelfarbwerk.
DE58904326D1 (de)	1993-06-17	Rakelfarbwerk.
DE58902774D1 (de)	1992-12-24	Pflanztafel.
DE68909215D1 (de)	1993-10-21	Laseroszillator.
FI891299A0 (fi)	1989-03-20	Straolningskaensliga silikonpolymerer.
DE58902346D1 (de)	1992-11-05	Traenkeventil.
DE58903112D1 (de)	1993-02-04	Kannenstock.
DE58902190D1 (de)	1992-10-08	Schaelmaschine.
FI891511A0 (fi)	1989-03-29	Kontrollsystem foer datarutter.
FI891294A (fi)	1989-09-23	Modifierade terpolymer-emulsioner.
NO903307D0 (no)	1990-07-25	Paramagnetiske forbindelser.
DE58900554D1 (de)	1992-01-23	Aminoguanidinoazine.
DE58903712D1 (de)	1993-04-15	Gegenseheinrichtung.
FI83400B (fi)	1991-03-28	Faestningsklaemma.
FI880914A0 (fi)	1988-02-26	Behaollarelement.
ES1007880Y (es)	1989-09-01	Munequera magnetica.
ES1007733Y (es)	1989-09-01	Arqueta.
FI80861B (fi)	1990-04-30	Plastdosa.
ATE86241T1 (de)	1993-03-15	Indanderivate.

Legal Events

Date	Code	Title	Description
1996-07-05	FD	Application lapsed
2004-08-31	FD	Application lapsed	Owner name: NYCOMED AS