FI895447A0 - Substituerade adeninderivat anvaendbara som terapeutiska substanser. - Google Patents

Substituerade adeninderivat anvaendbara som terapeutiska substanser.

Info

Publication number: FI895447A0
Authority: FI; Finland
Prior art keywords: terapeutiska; substanser; adeninderivat; substitute; anvaendbara som
Prior art date: 1988-03-16

Application number

FI895447A

Other languages

English (en)

Finnish (fi)

Other versions

FI895447A7 (fi

Inventor

Dennis A Carson

Carlos J Carrera

Original Assignee

Scripps Clinic Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-16

Filing date

1989-03-16

Publication date

1989-11-15

1989-03-16 Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res

1989-11-15 Publication of FI895447A7 publication Critical patent/FI895447A7/fi

1989-11-15 Publication of FI895447A0 publication Critical patent/FI895447A0/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/19—Purine radicals with arabinosyl as the saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Virology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Table Equipment (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Orthopedics, Nursing, And Contraception (AREA)

FI895447A 1988-03-16 1989-03-16 Substituerade adeninderivat anvaendbara som terapeutiska substanser. FI895447A0 (fi)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US16961888A	1988-03-16	1988-03-16
US32335089A	1989-03-14	1989-03-14
PCT/US1989/001088 WO1989008658A1 (en)	1988-03-16	1989-03-16	Substituted adenine derivatives useful as therapeutic agents

Publications (2)

Publication Number	Publication Date
FI895447A7 FI895447A7 (fi)	1989-11-15
FI895447A0 true FI895447A0 (fi)	1989-11-15

Family

ID=26865224

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI895447A FI895447A0 (fi)	1988-03-16	1989-03-16	Substituerade adeninderivat anvaendbara som terapeutiska substanser.

Country Status (9)

Country	Link
EP (1)	EP0364559B1 (de)
JP (1)	JP3090456B2 (de)
KR (1)	KR0138996B1 (de)
AT (1)	ATE128141T1 (de)
AU (1)	AU626296B2 (de)
CA (1)	CA1339964C (de)
DE (1)	DE68924319T2 (de)
FI (1)	FI895447A0 (de)
WO (1)	WO1989008658A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5310732A (en) *	1986-02-03	1994-05-10	The Scripps Research Institute	2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
US5384310A (en) *	1989-05-23	1995-01-24	Southern Research Institute	2'-fluoro-2-haloarabinoadinosines and their pharmaceutical compositions
US5034518A (en) *	1989-05-23	1991-07-23	Southern Research Institute	2-fluoro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl) adenine nucleosides
US5420115A (en) *	1990-09-10	1995-05-30	Burroughs Wellcome Co.	Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides
WO1992011276A1 (en) *	1990-12-18	1992-07-09	Sloan-Kettering Institute For Cancer Research	Novel synthesis of 2'-'up' fluorinated 2''-deoxy-arabinofuranosylpurines
GB9301000D0 (en) *	1993-01-20	1993-03-10	Glaxo Group Ltd	Chemical compounds
IL108524A0 (en) *	1993-02-03	1994-05-30	Gensia Inc	Imidazodiazepine analogs
WO1995032718A1 (en) *	1994-05-26	1995-12-07	The Scripps Research Institute	2-halo-2'-deoxyadenosine treatement for inflammatory bowel disease
AU735319B2 (en) *	1994-05-26	2001-07-05	Scripps Research Institute, The	2-halo-2'-deoxyadenosine treatment for inflammatory bowel disease
US5559114A (en) *	1994-12-16	1996-09-24	Exley; Ray W.	Treatment of autoimmune disease using 2-amino purine derivatives
DE19832519A1 (de) *	1998-07-20	2000-01-27	Hartmut Oswald	Arzneimittelzubereitungen zur topischen Behandlung mukokutaner Herpesinfektionen sowie der Keratitis herpetica des Auges
PT1261350E (pt) *	2000-02-18	2006-11-30	Southern Res Inst	Processos para síntese de 2-cloro-9-(2-desoxi-2-fluoro-b-d-arabinofuranosil)-9h-purin-6-amina
US7528247B2 (en)	2001-08-02	2009-05-05	Genzyme Corporation	Process for preparing purine nucleosides
CA2500091A1 (en) *	2002-09-27	2004-04-08	Bioenvision, Inc.	Methods and compositions for the treatment of lupus using clofarabine
US20060100167A1 (en)	2002-09-27	2006-05-11	Wood Christopher B	Methods and compositions for the treatment of autoimmune disorders using clofarabine
EP1768662A2 (de)	2004-06-24	2007-04-04	Novartis Vaccines and Diagnostics, Inc.	Immunstimulatoren kleiner moleküle und assays für deren nachweis
JP6510621B2 (ja) *	2017-11-29	2019-05-08	華安醫學股分有限公司ＥｎｅｒｇｅｎｅｓｉｓＢｉｏｍｅｄｉｃａｌＣｏ．，Ｌｔｄ．	活性化ａｍｐｋの化合物及びその使用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3539550A (en) *	1967-01-23	1970-11-10	Syntex Corp	Process for the preparation of 2'-halo-2'-deoxy pyrimidine nucleosides
US3472838A (en) *	1967-12-01	1969-10-14	Parke Davis & Co	9 - (beta - d - arabinofuranosyl) - 6 - (amidino) purine compounds and methods for their production
BE759011A (fr) *	1969-11-17	1971-05-17	Wellcome Found	Aminopurines
GB1386585A (en) *	1970-11-16	1975-03-12	Wellcome Found	Purine sugar derivatives
US4081534A (en) *	1973-09-11	1978-03-28	Burroughs Wellcome Co.	Amino purine nucleosides as autoimmune suppressant agents
US4526988A (en) *	1983-03-10	1985-07-02	Eli Lilly And Company	Difluoro antivirals and intermediate therefor
US4751221A (en) *	1985-10-18	1988-06-14	Sloan-Kettering Institute For Cancer Research	2-fluoro-arabinofuranosyl purine nucleosides
GB8708050D0 (en) *	1987-04-03	1987-05-07	Wellcome Found	Therapeutic nucleosides
CA1340645C (en) *	1987-04-17	1999-07-13	Victor E. Marquez	Acid stable dideoxynucleosides active against the cytopathic effects of human immunodeficiency virus
NZ226672A (en) *	1987-10-30	1991-07-26	Hoffmann La Roche	6-amino-9-(2,3-dideoxy-2-fluoro-b-d-threopentofuranosyl)-9h-purine derivatives and pharmaceutical compositions

1989
- 1989-03-16 AU AU34105/89A patent/AU626296B2/en not_active Expired
- 1989-03-16 FI FI895447A patent/FI895447A0/fi not_active Application Discontinuation
- 1989-03-16 JP JP01504299A patent/JP3090456B2/ja not_active Expired - Lifetime
- 1989-03-16 CA CA000593979A patent/CA1339964C/en not_active Expired - Lifetime
- 1989-03-16 EP EP89904431A patent/EP0364559B1/de not_active Expired - Lifetime
- 1989-03-16 WO PCT/US1989/001088 patent/WO1989008658A1/en active IP Right Grant
- 1989-03-16 AT AT89904431T patent/ATE128141T1/de not_active IP Right Cessation
- 1989-03-16 DE DE68924319T patent/DE68924319T2/de not_active Expired - Lifetime
- 1989-03-16 KR KR1019890702130A patent/KR0138996B1/ko not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0364559B1 (de)	1995-09-20
KR0138996B1 (ko)	1998-04-30
AU3410589A (en)	1989-10-05
AU626296B2 (en)	1992-07-30
EP0364559A4 (en)	1991-01-09
KR900700495A (ko)	1990-08-13
DE68924319T2 (de)	1996-05-15
JP3090456B2 (ja)	2000-09-18
JPH03501258A (ja)	1991-03-22
ATE128141T1 (de)	1995-10-15
EP0364559A1 (de)	1990-04-25
WO1989008658A1 (en)	1989-09-21
CA1339964C (en)	1998-07-21
DE68924319D1 (de)	1995-10-26
FI895447A7 (fi)	1989-11-15

Publication	Publication Date	Title
FI895447A0 (fi)	1989-11-15	Substituerade adeninderivat anvaendbara som terapeutiska substanser.
BR9305907A (pt)	1997-10-21	Uso de derivados de substituída para tratamento de esclerose múltipla
KR950700298A (ko)	1995-01-16	뉴클레오시드 치료제(Therapeutic Nucleosides)
DK0813525T3 (da)	2004-02-16	Benzamidinderivater, deres fremstilling og anvendelse som antikoagulanter
FI834872A0 (fi)	1983-12-30	Substituerade 4-aminoetylen-kromaner och -kromener, foerfaranden foer deras framstaellning och deraanvaendning som laekemedel
DE3774918D1 (de)	1992-01-16	Cancerostatisches mittel.
ES2037013T3 (es)	1993-06-16	Procedimiento para preparar tieno-1,4-diazepinas.
DE3873007D1 (de)	1992-08-27	Kathartica.
ATE69953T1 (de)	1991-12-15	Verwendung von polysulfatierten heparinen.
ES507807A0 (es)	1982-10-01	Procedimiento para la obtencion de derivados triciclicos de citosina.
DK621487A (da)	1988-01-26	Fremgangsmaade til oegning af adenosinexkretion
PT88150A (pt)	1989-06-30	Processo para a preparacao de uma composicao farmaceutica combinada contendo um polissacarido sulfatado e um derivado de xantina
DK217488D0 (da)	1988-04-21	17beta-(cyclopropyloxy(thio))-androst-5-en-3beta-olderivater, deres fremstilling og anvendelse som laegemidler
ES2016464A6 (es)	1990-11-01	Procedimiento para preparar derivados de 2', 5' -oligoadenilato.
SE7902866L (sv)	1979-10-16	3-0-(beta-d-glukuronopyranosyl)-sojasapogenol b
ES2018807B3 (es)	1991-05-16	Procedimiento para curtir el cuero
ES2052483T1 (es)	1994-07-16	Nuevos derivados del 3,3,5-trimetilciclohexanol, su procedimiento de preparacion asi como las composiciones terapeuticas que los contienen.
ES2073919T3 (es)	1995-08-16	Derivados de piperidina 1,3,4-trisubstituidos, su obtencion y empleo.
DK572189A (da)	1989-11-15	Substituerede adeninderivater og farmaceutisk praeparat indeholdende dem
NO960849L (no)	1996-03-01	Difluorstaton-antivirale analoger
ES2059097T3 (es)	1994-11-01	Derivados de la ergolina.
SE8202433L (sv)	1982-10-21	Linkomycin-3-(5'-ribonukleotider)lempade for behandling av protosoriska sjukdomar
ES2034017T3 (es)	1993-04-01	Procedimiento para la obtencion de 3-fenil-2-estril-pirrolidinas.

Legal Events

Date	Code	Title	Description
1993-07-15	FD	Application lapsed
2004-08-31	FD	Application lapsed	Owner name: SCRIPPS CLINIC AND RESEARCH FOUNDATION