FI893162L - Som 19-hydroxylasinhibitorer anvaendbara 19-fluor- eller cyano-21-hydroxiprogesteronderivat. - Google Patents

Som 19-hydroxylasinhibitorer anvaendbara 19-fluor- eller cyano-21-hydroxiprogesteronderivat. Download PDF

Info

Publication number: FI893162L
Authority: FI; Finland
Prior art keywords: hydroxylasinhibitorer; hydroxiprogesteronderivat; anvaendbara; eller; som
Prior art date: 1988-06-28

Application number

FI893162A

Other languages

English (en)

Other versions

FI893162A0 (fi

Inventor

Gene Warwick Holbert

John O'neal Johnston

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-06-28

Filing date

1989-06-28

Publication date

1989-12-29

1989-06-28 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-06-28 Publication of FI893162A0 publication Critical patent/FI893162A0/fi

1989-12-29 Publication of FI893162L publication Critical patent/FI893162L/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Manufacture Of Macromolecular Shaped Articles (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Organic Insulating Materials (AREA)

FI893162A 1988-06-28 1989-06-28 Som 19-hydroxylasinhibitorer anvaendbara 19-fluor- eller cyano-21-hydroxiprogesteronderivat. FI893162L (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/212,410 US4920114A (en)	1988-06-28	1988-06-28	19-fluoro- or cyano-21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors

Publications (2)

Publication Number	Publication Date
FI893162A0 FI893162A0 (fi)	1989-06-28
FI893162L true FI893162L (fi)	1989-12-29

Family

ID=22790899

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI893162A FI893162L (fi)	1988-06-28	1989-06-28	Som 19-hydroxylasinhibitorer anvaendbara 19-fluor- eller cyano-21-hydroxiprogesteronderivat.

Country Status (19)

Country	Link
US (1)	US4920114A (fi)
EP (1)	EP0348911B1 (fi)
JP (1)	JP2727466B2 (fi)
KR (1)	KR0140885B1 (fi)
CN (1)	CN1039424A (fi)
AT (1)	ATE100462T1 (fi)
AU (1)	AU610413B2 (fi)
CA (1)	CA1321579C (fi)
DE (1)	DE68912422T2 (fi)
DK (1)	DK318489A (fi)
ES (1)	ES2061802T3 (fi)
FI (1)	FI893162L (fi)
HU (1)	HUT51289A (fi)
IL (1)	IL90728A0 (fi)
NO (1)	NO892679L (fi)
NZ (1)	NZ229694A (fi)
PH (1)	PH25771A (fi)
PT (1)	PT90989B (fi)
ZA (1)	ZA894753B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4433374A1 (de) *	1994-09-20	1996-03-21	Hoechst Ag	17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US6787530B1 (en)	1996-08-23	2004-09-07	Monash University	Use of pregnane-diones as analgesic agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3124574A (en) *		1964-03-10		Iz-halo pregnenes
IT1051705B (it) *	1962-05-12	1981-05-20	Vismara Spa F	Metodo per la preparazione di intermedi steroidali
US3154569A (en) *	1961-10-10	1964-10-27	Vismara Francesco Spa	19-nitrilosteroids and process for producing 19-norsteroids
GB984093A (en) *	1962-02-19	1965-02-24	Syntex Corp	Improvements in or relating to 19-halo-pregnane compounds
US3257435A (en) *	1962-09-21	1966-06-21	Syntex Corp	19-bisdifluoro pregnanes
US3257389A (en) *	1962-09-21	1966-06-21	Syntex Corp	19-bisdifluoro-pregnanes
US3205228A (en) *	1963-03-01	1965-09-07	Syntex Corp	19-substituted pregnenes
US3159620A (en) *	1963-05-22	1964-12-01	Vismara Francesco Spa	Process for the preparation of 17 alpha-ethynyl-19-norandrostene compounds
US3394128A (en) *	1964-09-26	1968-07-23	Syntex Corp	19-halo-androstane and pregnane derivatives and processes for the preparation thereof
FR2462445A1 (fr) *	1979-07-31	1981-02-13	Roussel Uclaf	Nouveaux derives 17-/(hydroxymethyl) (formamido) methylene/steroides, leur procede de preparation et leur application a l'introduction de la chaine laterale hydroxyacetyle
US4293548A (en) *	1980-09-02	1981-10-06	Merrell Dow Pharmaceuticals Inc.	18-Substituted pregn-4-ene-3,20-diones

1988
- 1988-06-28 US US07/212,410 patent/US4920114A/en not_active Expired - Lifetime
1989
- 1989-06-22 ZA ZA894753A patent/ZA894753B/xx unknown
- 1989-06-23 IL IL90728A patent/IL90728A0/xx not_active IP Right Cessation
- 1989-06-23 NZ NZ229694A patent/NZ229694A/en unknown
- 1989-06-26 KR KR1019890008781A patent/KR0140885B1/ko not_active Expired - Fee Related
- 1989-06-27 CN CN89106339A patent/CN1039424A/zh active Pending
- 1989-06-27 CA CA000604022A patent/CA1321579C/en not_active Expired - Lifetime
- 1989-06-27 DE DE68912422T patent/DE68912422T2/de not_active Expired - Lifetime
- 1989-06-27 NO NO89892679A patent/NO892679L/no unknown
- 1989-06-27 ES ES89111699T patent/ES2061802T3/es not_active Expired - Lifetime
- 1989-06-27 AT AT89111699T patent/ATE100462T1/de not_active IP Right Cessation
- 1989-06-27 JP JP1162845A patent/JP2727466B2/ja not_active Expired - Lifetime
- 1989-06-27 EP EP89111699A patent/EP0348911B1/en not_active Expired - Lifetime
- 1989-06-27 DK DK318489A patent/DK318489A/da not_active Application Discontinuation
- 1989-06-27 HU HU893242A patent/HUT51289A/hu unknown
- 1989-06-27 PT PT90989A patent/PT90989B/pt not_active IP Right Cessation
- 1989-06-27 PH PH38862A patent/PH25771A/en unknown
- 1989-06-28 FI FI893162A patent/FI893162L/fi not_active Application Discontinuation
- 1989-06-28 AU AU37126/89A patent/AU610413B2/en not_active Ceased

Also Published As

Publication number	Publication date
FI893162A0 (fi)	1989-06-28
PH25771A (en)	1991-10-18
DE68912422D1 (de)	1994-03-03
CA1321579C (en)	1993-08-24
JP2727466B2 (ja)	1998-03-11
DK318489A (da)	1989-12-29
NO892679D0 (no)	1989-06-27
HUT51289A (en)	1990-04-28
EP0348911A3 (en)	1990-03-28
ATE100462T1 (de)	1994-02-15
AU3712689A (en)	1990-01-04
EP0348911B1 (en)	1994-01-19
DE68912422T2 (de)	1994-08-18
KR0140885B1 (ko)	1998-06-15
AU610413B2 (en)	1991-05-16
ZA894753B (en)	1990-03-28
PT90989B (pt)	1994-11-30
DK318489D0 (da)	1989-06-27
JPH0248597A (ja)	1990-02-19
ES2061802T3 (es)	1994-12-16
IL90728A0 (en)	1990-01-18
NO892679L (no)	1989-12-29
EP0348911A2 (en)	1990-01-03
PT90989A (pt)	1989-12-29
CN1039424A (zh)	1990-02-07
NZ229694A (en)	1992-03-26
KR900000321A (ko)	1990-01-30
US4920114A (en)	1990-04-24

Publication	Publication Date	Title
FI893334L (fi)	1990-01-09	Trycksensitiva bindemedel som innehaoller en alkoxifunktionell kiselfoerening.
FI896138A0 (fi)	1989-12-20	Polyolpolyestrar som fuktighetsbarriaer foer livsmedel.
FI895792A0 (fi)	1989-12-04	Bild-display-anordning som anvaender alternering i svepriktning.
FI921279L (fi)	1992-03-25	Amino-b-lyasenzyminhibitorer som deodoranter.
FI881570L (fi)	1989-10-06	Differentialutgaongens koppling som enpolig.
FI900763A0 (fi)	1990-02-15	Tris-hydroximetyl-laegre alkanestrar som fettsurrogat.
FI881910L (fi)	1989-10-23	Underlag i synnerhet foer personer som saknar roerelsefoermaoga.
FI894600L (fi)	1990-03-29	Ny sammansaettning som innehaoller isocyanat-reaktiva vaete innehaollande foereningar.
FI892214L (fi)	1990-11-10	Kopparlegering foer anvaendning som motstaondssvetselektrod.
FI895483L (fi)	1991-05-18	Som slaglod anvaendbara kopparblandningar.
FI890033A0 (fi)	1989-01-04	Bildskaermanordning som innehaoller en vaogformsgenerator.
FI890147A0 (fi)	1989-01-12	Aemnen som motverkar rytmstoerningar.
FI890798L (fi)	1989-08-19	Foerfarande foer diacylering av foereningar som innehaoller tvao aromatiska kaernor.
FI900940A0 (fi)	1990-02-23	Tryckt kretsskiva som foerhindrar elektromagnetisk interferens.
FI893863L (fi)	1990-02-20	Foerfarande foer neutralisering av svavelsyra som innehaoller zinkjoner.
FI905238A0 (fi)	1990-10-24	Foerbraenningsmotor foer fartyg som transporterar foerbraenningsgas.
FI922124L (fi)	1992-05-11	Azabicykloamider och -estrar som 5-ht3-receptorantagonister.
FI894475A0 (fi)	1989-09-21	Anvaendning av sampolymerisat innehaollande aminogrupper i vattenbaserade kompositioner som grundfaerg.
FI893162L (fi)	1989-12-29	Som 19-hydroxylasinhibitorer anvaendbara 19-fluor- eller cyano-21-hydroxiprogesteronderivat.
FI905274A0 (fi)	1990-10-25	Katod som frigoer vaete.
FI881817A0 (fi)	1988-04-19	Maskinhelhet som hopsaetts av luftkonditionerings-,luftrenings-,vaermeutjaemnings-och dammsugningsmoduler.
FI910281A0 (fi)	1991-01-18	Kopplingsarrangemang som bildar triangelpuls.
FI881591A0 (fi)	1988-04-06	Vaermeradiator som lagrar vaermeenergi.
FI894664A0 (fi)	1989-10-02	Inpassningskil foer vaeggelement som skall sammanfogas.
FI880902A0 (fi)	1988-02-26	Landsvaegskonstruktion som minskar spaorbildning.

Legal Events

Date	Code	Title	Description
1994-02-06	FD	Application lapsed
2004-08-31	FD	Application lapsed	Owner name: MERRELL DOW PHARMACEUTICALS INC.