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FI873398A - EXAMINATION OF CLINICAL PARAMETERS WITH ENHANCED IMMUNOPROCESS. - Google Patents

EXAMINATION OF CLINICAL PARAMETERS WITH ENHANCED IMMUNOPROCESS. Download PDF

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Publication number
FI873398A
FI873398A FI873398A FI873398A FI873398A FI 873398 A FI873398 A FI 873398A FI 873398 A FI873398 A FI 873398A FI 873398 A FI873398 A FI 873398A FI 873398 A FI873398 A FI 873398A
Authority
FI
Finland
Prior art keywords
immunoprocess
antigens
enzyme
clinical parameters
antibodies
Prior art date
Application number
FI873398A
Other languages
Finnish (fi)
Other versions
FI85194B (en
FI85194C (en
FI873398A0 (en
Inventor
Ennio Iaccheri
Paola Piro
Claudio Manzati
Original Assignee
Boehringer Biochemia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Srl filed Critical Boehringer Biochemia Srl
Publication of FI873398A publication Critical patent/FI873398A/en
Publication of FI873398A0 publication Critical patent/FI873398A0/en
Publication of FI85194B publication Critical patent/FI85194B/en
Application granted granted Critical
Publication of FI85194C publication Critical patent/FI85194C/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54391Immunochromatographic test strips based on vertical flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Method and device for determination of clinical parameters and biological fluids with an enzymatic immunoprocess in which the biological fluid is successively brought into contact (a) with enzyme-labeled antibodies or antigens that are adsorbed on a solid carrier reversibly; (b) with antibodies, antigens, anti antibodies or a complex between an antigen and an antibody, which are immobilized on a solid carrier in an amount that is stoichiometrically the same as the amounts of enzyme-labeled antibodies or antigens; (c) with one or more such chromogenic substrates that have a capacity to produce a detecting reaction with an enzyme that is conjugated to an antibody or antigen.
FI873398A 1985-02-08 1987-08-05 Determination of clinical parameters using an enzymatic immunoprocess FI85194C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT1944385 1985-02-08
IT19443/85A IT1200382B (en) 1985-02-08 1985-02-08 DETECTION AND / OR DOSAGE SYSTEM OF CLINICAL PARAMETERS BY IMMUNO ENZYMATIC ROUTE
EP8600055 1986-02-02
PCT/EP1986/000055 WO1986004683A1 (en) 1985-02-08 1986-02-02 Determination of clinical parameters by enzyme immunoprocess

Publications (4)

Publication Number Publication Date
FI873398A true FI873398A (en) 1987-08-05
FI873398A0 FI873398A0 (en) 1987-08-05
FI85194B FI85194B (en) 1991-11-29
FI85194C FI85194C (en) 1992-03-10

Family

ID=11158028

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873398A FI85194C (en) 1985-02-08 1987-08-05 Determination of clinical parameters using an enzymatic immunoprocess

Country Status (12)

Country Link
EP (1) EP0243370A1 (en)
JP (1) JPS62501989A (en)
AU (1) AU5511886A (en)
DD (1) DD245727A5 (en)
ES (5) ES8802256A1 (en)
FI (1) FI85194C (en)
HU (1) HUT56632A (en)
IT (1) IT1200382B (en)
MW (1) MW5287A1 (en)
OA (1) OA08640A (en)
RO (1) RO100056A2 (en)
WO (1) WO1986004683A1 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
CA1289872C (en) * 1986-06-18 1991-10-01 David L. Woodrum Reversible immobilization of assay reagents in a multizone test device
US4959305A (en) * 1986-06-18 1990-09-25 Miles Inc. Reversible immobilization of assay reagents in a multizone test device
ES2004066A6 (en) * 1987-01-21 1988-12-01 Euro Fassel Aktiebolag A kit for qualitative and quantitative analysis of antigens, antibodies and/or microorganisms or other cells
AU592174B2 (en) * 1987-02-17 1990-01-04 Genesis Labs, Inc. Immunoassay test strip
AU586552B2 (en) * 1987-02-25 1989-07-13 Genesis Labs, Inc. Dry test strip for devices using oxygen demanding detection system
ATE195022T1 (en) * 1987-04-27 2000-08-15 Unilever Nv SPECIFIC BINDING TESTING METHODS
DE3878820T2 (en) * 1987-04-29 1993-07-22 Celltech Ltd DEVICE FOR BINDING TEST.
US5641639A (en) * 1987-04-29 1997-06-24 Celltech Therapeutics Limited Binding assay device
IT1223295B (en) * 1987-08-14 1990-09-19 Boehringer Biochemia Srl IMMUNODIAGNOSTIC DEVICE AND METHOD
FR2621393B1 (en) * 1987-10-05 1991-12-13 Toledano Jacques DEVICE FOR IMMUNOENZYMATIC DETECTION OF SUBSTANCES FROM A DROP OF BLOOD OR LIQUID FROM ANY BIOLOGICAL MEDIUM
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5338513A (en) * 1988-07-30 1994-08-16 Boehringer Mannheim Gmbh Test carrier for the analytical determination of a component of a liquid sample
FR2634891B1 (en) * 1988-08-01 1994-05-06 Biotrol Laboratoires METHOD AND DEVICE FOR THE QUALITATIVE AND / OR QUANTITATIVE DETERMINATION OF A LIGAND IN A FLUID
US5079174A (en) * 1988-12-08 1992-01-07 Boehringer Mannheim Corporation Apparatus for sequential determination of an analyte in a fluid sample
DE3842702A1 (en) * 1988-12-19 1990-06-21 Boehringer Mannheim Gmbh TEST CARRIER FOR ANALYTICAL EXAMINATION OF A SAMPLING LIQUID WITH THE AID OF A SPECIFIC BINDING REACTION OF TWO BIOAFFIN BINDING PARTNERS AND A CORRESPONDING TEST PROCEDURE
GB8903627D0 (en) * 1989-02-17 1989-04-05 Unilever Plc Assays
AU2247192A (en) * 1991-06-13 1993-01-12 Pacific Biotech, Inc. Assay for the detection of specific ligands
DE4121493A1 (en) * 1991-06-28 1993-01-07 Draegerwerk Ag ANALYSIS DEVICE FOR THE QUANTITATIVE, IMMUNOLOGICAL DETERMINATION OF POLLUTANTS
FI92882C (en) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Disposable test strip and process for its manufacture
FR2725023B1 (en) * 1994-09-28 1997-01-31 Gks Technologies DIRECT DIAGNOSIS OF HAPTENES
JP3010699U (en) * 1994-10-29 1995-05-02 株式会社ニッポンジーン Chromatographic inspection device capable of direct urine collection
FR2917171A1 (en) * 2007-06-07 2008-12-12 Biosynex Sarl Detection of molecule of interest e.g. peptide in liquid sample by contacting the sample with first antibody, contacting the antibody with marked conjugate, contacting the first antibody with second antibody, and analysis of test zone
CN102095860B (en) * 2011-01-25 2013-12-18 厦门大学附属中山医院 Syphilis specific IgG antibody western blot kit and preparation method thereof
EP4062066A1 (en) 2019-11-22 2022-09-28 Nano Scale Machining GmbH Fluid machine, in particular hydraulic machine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2644249A1 (en) * 1976-09-30 1978-04-06 Abbott Lab Reactive, stable metal and organic cpd. compsns. - comprising metal surface coated with polymer and coupled to enzymes, protein(s) etc.
US4320111A (en) * 1977-06-14 1982-03-16 American Home Products Corporation Immunologic compositions methods of preparation and use
US4189304A (en) * 1978-10-27 1980-02-19 Miles Laboratories, Inc. Device and method for detecting myoglobin
US4331650A (en) * 1980-07-18 1982-05-25 Science Research Center, Inc. Identification of reagins in the blood serum of allergen sensitized vertebrates
JPS5818167A (en) * 1981-07-24 1983-02-02 Fuji Photo Film Co Ltd Analyzing film and analysis using said film
US4446232A (en) * 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens
US4447546A (en) * 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
DE3484505D1 (en) * 1983-12-19 1991-05-29 Daiichi Pure Chemicals Co Ltd IMMUNTEST.

Also Published As

Publication number Publication date
ES551760A0 (en) 1988-04-16
WO1986004683A1 (en) 1986-08-14
EP0243370A1 (en) 1987-11-04
ES557662A0 (en) 1988-11-16
DD245727A5 (en) 1987-05-13
AU5511886A (en) 1986-08-26
RO100056B1 (en) 1990-10-30
ES557818A0 (en) 1988-04-16
ES557803A0 (en) 1988-04-16
IT8519443A0 (en) 1985-02-08
ES8802260A1 (en) 1988-04-16
IT1200382B (en) 1989-01-18
FI85194B (en) 1991-11-29
ES8900067A1 (en) 1988-11-16
JPS62501989A (en) 1987-08-06
ES557802A0 (en) 1988-04-16
OA08640A (en) 1988-11-30
FI85194C (en) 1992-03-10
ES8802258A1 (en) 1988-04-16
FI873398A0 (en) 1987-08-05
RO100056A2 (en) 1991-03-23
MW5287A1 (en) 1988-11-09
ES8802256A1 (en) 1988-04-16
ES8802259A1 (en) 1988-04-16
HUT56632A (en) 1991-09-30

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Owner name: BOEHRINGER BIOCHEMIA ROBIN S.P.A.