FI833270A - Foerfarande foer avskiljning av optiska isomerer - Google Patents

Foerfarande foer avskiljning av optiska isomerer Download PDF

Info

Publication number: FI833270A
Authority: FI; Finland
Prior art keywords: optiska; isomerer; foerfarande foer; avskiljning; foer avskiljning
Prior art date: 1982-09-13

Application number

FI833270A

Other languages

English (en)

Other versions

FI833270A0 (fi

FI83767B (fi

FI83767C (fi

Inventor

Ronald D Dennis

Terence M Dolak

William Kreighbaum

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-09-13

Filing date

1983-10-13

Publication date

1984-03-14

1983-09-13 Publication of FI833270A0 publication Critical patent/FI833270A0/fi

1983-10-13 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1984-03-14 Publication of FI833270A publication Critical patent/FI833270A/fi

1991-05-15 Publication of FI83767B publication Critical patent/FI83767B/fi

1991-08-26 Application granted granted Critical

1991-08-26 Publication of FI83767C publication Critical patent/FI83767C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

FI833270A 1982-09-13 1983-10-13 Foerfarande foer uppspjaelkning av en racemisk form av -adrenergiska aryl- eller heteroaryloxipropanolaminer till sina optiskt aktiva isomerer, mellanprodukt vid foerfarandet foer framstaellning av mellanprodukten. FI83767C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US41779482		1982-09-13
US06/417,794 US4463176A (en)	1982-09-13	1982-09-13	Process for resolution of optical isomers

Publications (4)

Publication Number	Publication Date
FI833270A0 FI833270A0 (fi)	1983-09-13
FI833270A true FI833270A (fi)	1984-03-14
FI83767B FI83767B (fi)	1991-05-15
FI83767C FI83767C (fi)	1991-08-26

Family

ID=23655420

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI833270A FI83767C (fi)	1982-09-13	1983-10-13	Foerfarande foer uppspjaelkning av en racemisk form av -adrenergiska aryl- eller heteroaryloxipropanolaminer till sina optiskt aktiva isomerer, mellanprodukt vid foerfarandet foer framstaellning av mellanprodukten.

Country Status (29)

Country	Link
US (1)	US4463176A (fi)
JP (2)	JPS5980616A (fi)
KR (1)	KR890000616B1 (fi)
AT (1)	AT385032B (fi)
AU (1)	AU573535B2 (fi)
BE (1)	BE897737A (fi)
CA (1)	CA1250290A (fi)
CH (1)	CH660732A5 (fi)
CY (1)	CY1543A (fi)
DE (1)	DE3333025A1 (fi)
DK (2)	DK172720B1 (fi)
ES (1)	ES525543A0 (fi)
FI (1)	FI83767C (fi)
FR (1)	FR2540490B1 (fi)
GB (2)	GB2127020B (fi)
GR (1)	GR81546B (fi)
HK (1)	HK97990A (fi)
HU (1)	HU193183B (fi)
IE (1)	IE55650B1 (fi)
IL (1)	IL69708A (fi)
IT (1)	IT1170213B (fi)
LU (1)	LU84998A1 (fi)
NL (1)	NL8303154A (fi)
NO (1)	NO159267C (fi)
NZ (1)	NZ205554A (fi)
PT (1)	PT77331B (fi)
SE (2)	SE452608B (fi)
YU (1)	YU43327B (fi)
ZA (1)	ZA836795B (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4849527A (en) *	1982-09-13	1989-07-18	Bristol-Myers Company	Process for resolution of optical isomers
IT1163107B (it) *	1983-02-15	1987-04-08	Simes	Composizioni farmaceutiche e loro uso nel trattamento del glaucoma
US5364872A (en) *	1984-04-16	1994-11-15	Yamanouchi Pharmaceutical Co., Ltd.	Dihydropyridine-3,5-dicarboxylic acid ester derivatives
US5039801A (en) *	1985-12-20	1991-08-13	The United States Of America As Represented By The Department Of Health & Human Services	Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines
US4797498A (en) *	1986-07-18	1989-01-10	Pennwalt Corporation	Flavonoxypropanolamines and esters of flavonoxypropanolamines as antiarrhythmic agents
EP0305496A4 (en) *	1987-03-17	1989-07-11	Insite Vision Inc	TIMOLOL DERIVATIVES.
US4889941A (en) *	1987-04-23	1989-12-26	Fisons Corporation	Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase
US4806660A (en) *	1987-11-06	1989-02-21	Pennwalt Corporation	Aurone oxypropanolamines
JP2801768B2 (ja) *	1990-11-17	1998-09-21	日東電工株式会社	新規な光学活性メトプロロール・酒石酸誘導体塩及びその製法、並びにこの塩を用いる光学活性メトプロロールの製法
US5082970A (en) *	1991-03-06	1992-01-21	Pfizer Inc.	Process for recycling amine isomer
ES2065278B1 (es) *	1993-06-24	1995-09-01	Medichem Sa	Procedimiento de obtencion enantioselectivo del levobunolol.
AU702594B2 (en) *	1995-10-13	1999-02-25	Duphar International Research B.V.	Process for the preparation of enantiomerically pure imidazolyl compounds
KR100332399B1 (ko) *	1999-02-22	2002-04-13	김경호	메토프롤롤 라세미체로부터 메토프롤롤 에난티오머의 제조방법
BE1012622A3 (fr) *	1999-04-21	2001-01-09	Solvay	Procede pour la separation d'enantiomeres et reactif enantiopur.
US7138538B2 (en) *	2000-04-14	2006-11-21	Solvay (Societe Anonyme)	Process for the separation of enantiomers and enantiopure reagent
OA12905A (en)	2002-08-19	2006-10-13	Pfizer Prod Inc	Combination therapy for hyperproliferative diseases.
US20050037063A1 (en) *	2003-07-21	2005-02-17	Bolton Anthony E.	Combined therapies
GT200600381A (es)	2005-08-25	2007-03-28		Compuestos organicos
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
WO2008070496A2 (en)	2006-12-01	2008-06-12	Bristol-Myers Squibb Company	N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US9782488B2 (en)	2007-03-12	2017-10-10	Nektar Therapeutics	Oligomer-beta blocker conjugates
RU2618628C1 (ru)	2013-04-17	2017-05-05	Пфайзер Инк.	Производные N-пиперидин-3-илбензамида для лечения сердечно-сосудистых заболеваний
WO2016055901A1 (en)	2014-10-08	2016-04-14	Pfizer Inc.	Substituted amide compounds
CA3125765A1 (en)	2019-01-18	2020-07-23	Astrazeneca Ab	Pcsk9 inhibitors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US234595A (en) *		1880-11-16		Juan f
GB1211589A (en) *	1968-08-06	1970-11-11	Ici Ltd	Enantiomer isolation process
BE786963A (fr) *	1971-07-30	1973-01-29	Degussa	Procede pour le dedoublement racemique de d,1-phenylpropanolamine
US4314943A (en) *	1977-07-13	1982-02-09	Mead Johnson & Company	Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
US4234595A (en) *	1977-07-13	1980-11-18	Mead Johnson & Company	3-Indolyl-tertiary butylaminopropanols
IT1113029B (it) *	1979-03-01	1986-01-20	Simes	Processo per la separazione dei due isomeri ottici del moprololo e composizioni farmaceutiche dell'antipodo levogiro
JPS5770884A (en) *	1980-10-21	1982-05-01	Kyowa Hakko Kogyo Co Ltd	Novel piperidine derivative and its preparation
FI76551C (fi) *	1980-11-06	1988-11-10	Sandoz Ag	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-aminopropoxifenylderivat.

1982
- 1982-09-13 US US06/417,794 patent/US4463176A/en not_active Expired - Lifetime
1983
- 1983-09-12 CH CH4958/83A patent/CH660732A5/fr not_active IP Right Cessation
- 1983-09-12 LU LU84998A patent/LU84998A1/fr unknown
- 1983-09-12 NO NO833254A patent/NO159267C/no not_active IP Right Cessation
- 1983-09-12 IT IT22852/83A patent/IT1170213B/it active
- 1983-09-12 CA CA000436530A patent/CA1250290A/en not_active Expired
- 1983-09-12 BE BE0/211517A patent/BE897737A/fr not_active IP Right Cessation
- 1983-09-12 NZ NZ205554A patent/NZ205554A/en unknown
- 1983-09-12 SE SE8304887A patent/SE452608B/sv not_active IP Right Cessation
- 1983-09-12 FR FR8314464A patent/FR2540490B1/fr not_active Expired
- 1983-09-12 ES ES525543A patent/ES525543A0/es active Granted
- 1983-09-12 PT PT77331A patent/PT77331B/pt unknown
- 1983-09-12 GR GR72427A patent/GR81546B/el unknown
- 1983-09-12 IE IE2134/83A patent/IE55650B1/en not_active IP Right Cessation
- 1983-09-13 HU HU833181A patent/HU193183B/hu unknown
- 1983-09-13 JP JP58167667A patent/JPS5980616A/ja active Granted
- 1983-09-13 AU AU19081/83A patent/AU573535B2/en not_active Expired
- 1983-09-13 ZA ZA836795A patent/ZA836795B/xx unknown
- 1983-09-13 KR KR1019830004298A patent/KR890000616B1/ko not_active IP Right Cessation
- 1983-09-13 GB GB08324536A patent/GB2127020B/en not_active Expired
- 1983-09-13 DK DK198304164A patent/DK172720B1/da not_active IP Right Cessation
- 1983-09-13 AT AT0326383A patent/AT385032B/de not_active IP Right Cessation
- 1983-09-13 IL IL69708A patent/IL69708A/xx not_active IP Right Cessation
- 1983-09-13 DE DE19833333025 patent/DE3333025A1/de active Granted
- 1983-09-13 YU YU1846/83A patent/YU43327B/xx unknown
- 1983-09-13 NL NL8303154A patent/NL8303154A/nl active Search and Examination
- 1983-10-13 FI FI833270A patent/FI83767C/fi not_active IP Right Cessation
1986
- 1986-02-24 GB GB08604515A patent/GB2169294B/en not_active Expired
- 1986-06-18 SE SE8602724A patent/SE8602724D0/xx not_active Application Discontinuation
1990
- 1990-11-22 HK HK979/90A patent/HK97990A/xx not_active IP Right Cessation
1991
- 1991-03-22 CY CY1543A patent/CY1543A/xx unknown
- 1991-09-25 JP JP3315620A patent/JP2759184B2/ja not_active Expired - Lifetime
1997
- 1997-09-17 DK DK199701068A patent/DK172732B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK416483D0 (da)	1983-09-13
ES8504104A1 (es)	1985-04-16
NO159267C (no)	1988-12-14
IT1170213B (it)	1987-06-03
ATA326383A (de)	1987-07-15
FI833270A0 (fi)	1983-09-13
GB8604515D0 (en)	1986-04-03
FI83767B (fi)	1991-05-15
GB2169294A (en)	1986-07-09
ZA836795B (en)	1984-04-25
PT77331B (en)	1986-08-28
DE3333025C2 (fi)	1992-01-23
FR2540490B1 (fr)	1986-09-05
KR890000616B1 (ko)	1989-03-22
SE8304887L (sv)	1984-03-14
PT77331A (en)	1983-10-01
JP2759184B2 (ja)	1998-05-28
CY1543A (en)	1991-03-22
YU184683A (en)	1986-02-28
DK416483A (da)	1984-03-14
JPS5980616A (ja)	1984-05-10
SE8602724L (sv)	1986-06-18
AU1908183A (en)	1984-03-22
IL69708A0 (en)	1983-12-30
KR840005998A (ko)	1984-11-21
DK172720B1 (da)	1999-06-14
NO159267B (no)	1988-09-05
IE55650B1 (en)	1990-12-05
YU43327B (en)	1989-06-30
DE3333025A1 (de)	1984-03-29
GB8324536D0 (en)	1983-10-12
IL69708A (en)	1987-02-27
FI83767C (fi)	1991-08-26
SE8304887D0 (sv)	1983-09-12
IT8322852A0 (it)	1983-09-12
AU573535B2 (en)	1988-06-16
GB2127020A (en)	1984-04-04
HK97990A (en)	1990-11-30
NZ205554A (en)	1987-09-30
GB2127020B (en)	1987-05-07
CH660732A5 (fr)	1987-06-15
SE452608B (sv)	1987-12-07
GB2169294B (en)	1987-05-13
ES525543A0 (es)	1985-04-16
NO833254L (no)	1984-03-14
HU193183B (en)	1987-08-28
LU84998A1 (fr)	1984-04-24
JPH0414086B2 (fi)	1992-03-11
CA1250290A (en)	1989-02-21
BE897737A (fr)	1984-03-12
AT385032B (de)	1988-02-10
FR2540490A1 (fr)	1984-08-10
US4463176A (en)	1984-07-31
GR81546B (fi)	1984-12-11
IE832134L (en)	1984-03-13
NL8303154A (nl)	1984-04-02
DK106897A (da)	1997-09-17
SE8602724D0 (sv)	1986-06-18
DK172732B1 (da)	1999-06-21
JPH0859597A (ja)	1996-03-05

Publication	Publication Date	Title
FI834804A0 (fi)	1983-12-27	Av cellulosafyllning innehaollande etyleninterpolymerer framstaellda traelika foeremaol
FI830173A0 (fi)	1983-01-19	Fyllblandning av polyesterfibrer
FI830130A0 (fi)	1983-01-14	Anordning foer avskiljande av vaetska
FI833213A0 (fi)	1983-09-08	Roerkonstruktion foer foerflyttning av vaetskor
FI833270A (fi)	1984-03-14	Foerfarande foer avskiljning av optiska isomerer
FI824215A0 (fi)	1982-12-08	Foerfarande foer upploesning av cellulosakarbamat
FI831520A0 (fi)	1983-05-03	Foerfarande foer framstaellning av hydroxialkylmetylcellulosa
FI830288A0 (fi)	1983-01-27	Foerfarande foer behandling av kemiska pappersmassor
FI824482A0 (fi)	1982-12-28	Foerfarande foer foerstaerkning av fibervaevnader medelst vattenhaltiga plastdispersioner
FI832113A0 (fi)	1983-06-13	Framstaellning av vinylkarboxylsyraderivat
FI830896A0 (fi)	1983-03-17	Blaoshuvud foer framstaellning av en plastfolie
FI64260B (fi)	1983-07-29	Anordning foer foerdelning av en stroemning
FI833649A (fi)	1984-04-14	Behandling av cyanidhaltiga utfloeden
FI832817A0 (fi)	1983-08-04	Foerfarande foer framstaellning av alfaarylalkanosyror
FI834382A0 (fi)	1983-11-30	Foerfarande foer delignifierande blekning av cellulosamassa
FI821044L (fi)	1983-09-25	Taetning av ventillock
FI824297A0 (fi)	1982-12-14	Foerbaettrat foerfarande foer anvaendning av en elektrokemisk vaetske/gascell
FI830905A0 (fi)	1983-03-18	Foerbaettringar av dimensionsstabiliserat papper
FI822107L (fi)	1983-10-17	Foerfarande foer rengoering av gasgenomstroemningsvaermevaexlare
FI830996L (fi)	1983-09-30	Foerfarande foer framstaellning av en tvaolstaong
FI820403L (fi)	1983-08-10	Foerfarande foer framstaellning av betongmassa
FI834648A0 (fi)	1983-12-16	Foerfarande foer framstaellning av kefalosporinderivat
FI833255A (fi)	1984-03-17	Foerfarande foer framstaellning av pressprodukter av humle
FI820789L (fi)	1983-09-09	Foerfarande foer bildande av en vertikaldraen
FI833745A0 (fi)	1983-10-14	Anordning foer dosering av vaetskor

Legal Events

Date	Code	Title	Description
2004-08-31	MA	Patent expired	Owner name: BRISTOL-MYERS SQUIBB COMPANY