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FI61902C - Foerfarande foer framstaellning av farmakologiskt effektiva imdazo(5,1-c)(1,4)bensoxazin-1-on-derivat - Google Patents

Foerfarande foer framstaellning av farmakologiskt effektiva imdazo(5,1-c)(1,4)bensoxazin-1-on-derivat Download PDF

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Publication number
FI61902C
FI61902C FI763752A FI763752A FI61902C FI 61902 C FI61902 C FI 61902C FI 763752 A FI763752 A FI 763752A FI 763752 A FI763752 A FI 763752A FI 61902 C FI61902 C FI 61902C
Authority
FI
Finland
Prior art keywords
formula
compound
hydrogen
phenyl
benzoxazin
Prior art date
Application number
FI763752A
Other languages
English (en)
Finnish (fi)
Other versions
FI61902B (fi
FI763752A (fr
Inventor
Piero Melloni
Nicola Mongelli
Francesco Lauria
Alessandro Rossi
Raffaele Tommasini
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI763752A publication Critical patent/FI763752A/fi
Publication of FI61902B publication Critical patent/FI61902B/fi
Application granted granted Critical
Publication of FI61902C publication Critical patent/FI61902C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI763752A 1975-12-30 1976-12-30 Foerfarande foer framstaellning av farmakologiskt effektiva imdazo(5,1-c)(1,4)bensoxazin-1-on-derivat FI61902C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT30829/75A IT1052009B (it) 1975-12-30 1975-12-30 Imidazo 4.3 c 1.4 benzossazino imidazo 4.3 c 1.4 benzotiazino pirazo 2.1 c 1.4 benzossazino e pirazo 2.1 c 1.4 benzotiazino derivati
IT3082975 1975-12-30

Publications (3)

Publication Number Publication Date
FI763752A FI763752A (fr) 1977-07-01
FI61902B FI61902B (fi) 1982-06-30
FI61902C true FI61902C (fi) 1982-10-11

Family

ID=11232353

Family Applications (1)

Application Number Title Priority Date Filing Date
FI763752A FI61902C (fi) 1975-12-30 1976-12-30 Foerfarande foer framstaellning av farmakologiskt effektiva imdazo(5,1-c)(1,4)bensoxazin-1-on-derivat

Country Status (22)

Country Link
US (1) US4134974A (fr)
JP (1) JPS5283397A (fr)
AT (1) AT351041B (fr)
AU (1) AU504565B2 (fr)
BE (1) BE849919A (fr)
CA (1) CA1099267A (fr)
CH (1) CH630383A5 (fr)
CS (1) CS197301B2 (fr)
DE (1) DE2658806A1 (fr)
DK (1) DK587476A (fr)
FI (1) FI61902C (fr)
FR (1) FR2336929A1 (fr)
GB (1) GB1533020A (fr)
HU (1) HU176510B (fr)
IL (1) IL51091A (fr)
IT (1) IT1052009B (fr)
NL (1) NL7614445A (fr)
NO (1) NO150882C (fr)
NZ (1) NZ182952A (fr)
SE (1) SE7613778L (fr)
SU (1) SU812181A3 (fr)
ZA (1) ZA767588B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049422A (en) * 1976-03-29 1977-09-20 United States Borax & Chemical Corporation Herbicidal morpholinobenzimidazoles
SE444319B (sv) * 1977-11-18 1986-04-07 Roussel Uclaf Nya imidazobensoxazinderivat, forfarande for framstellning derav och farmaceutiska kompositioner innehallande dessa foreningar
US4254121A (en) * 1979-08-13 1981-03-03 Ayerst, Mckenna & Harrison Inc. 3-Oxo-5H-pyrimido[2,1-c][1,4 ]benzoxazines
US4254118A (en) * 1979-08-13 1981-03-03 Ayerst, Mckenna & Harrison Inc. 1-Oxo-5H-pyrimido[2,1-c][1,4]benzthiazine-2-carboxylic acid esters
US5166343A (en) * 1988-02-05 1992-11-24 Riker Laboratories, Inc. Triazolo[1,5-c]pyrimido[1,4]-azines as bronchodilators
US5089493A (en) * 1988-02-05 1992-02-18 Riker Laboratories, Inc. Triazolo[1,5-C]pyrimido[1,4]azines as bronchodilators
WO1993016082A1 (fr) * 1992-02-13 1993-08-19 The Upjohn Company Benzoxazines 4-oxo et 4h-imidazo(5,1-c)(1,4) utiles comme agents de liaison de recepteurs de benzodiazepine
GB9212486D0 (en) * 1992-06-12 1992-07-22 Erba Carlo Spa Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation
US5512566A (en) * 1993-10-25 1996-04-30 Ortho Pharmaceutical Corporation Tricyclic compounds having affinity for the 5-HT1A receptor
GB9410469D0 (en) * 1994-05-25 1994-07-13 Erba Farmitalia Imidazolylalkyl derivatives of imidazo (5,1-c) (1,4) benzoxazin-1-one and process for their preparation
AU4547796A (en) * 1995-02-03 1996-08-21 Sankyo Company Limited Hexahydropyrazinoquinoline derivatives
JP2009523820A (ja) * 2006-01-23 2009-06-25 アミラ ファーマシューティカルス，インコーポレーテッド ５−リポキシゲナーゼの三環系抑制剤
WO2014089904A1 (fr) 2012-12-10 2014-06-19 Abbvie Inc. Composés triazinones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929783A (en) * 1974-12-06 1975-12-30 Squibb & Sons Inc 1-Substituted-4-phenyl-4H-{8 1,2,4{9 triazolo{8 3,4-C{9 {8 1,4{9 {0 benzothiazines or benzoxazines
US4035495A (en) * 1975-02-10 1977-07-12 Ayerst Mckenna And Harrison Ltd. Pyrrolobenzoxazines, pyrrolobenzothiazines and process therefor

Also Published As

Publication number Publication date
SU812181A3 (ru) 1981-03-07
NO764395L (fr) 1977-07-01
FR2336929B1 (fr) 1980-04-18
NL7614445A (nl) 1977-07-04
BE849919A (fr) 1977-04-15
NZ182952A (en) 1980-05-08
IL51091A0 (en) 1977-02-28
AU2086376A (en) 1978-06-29
FI61902B (fi) 1982-06-30
FR2336929A1 (fr) 1977-07-29
US4134974A (en) 1979-01-16
FI763752A (fr) 1977-07-01
NO150882C (no) 1985-01-09
IT1052009B (it) 1981-06-20
SE7613778L (sv) 1977-07-01
DK587476A (da) 1977-07-01
AU504565B2 (en) 1979-10-18
IL51091A (en) 1984-01-31
CH630383A5 (de) 1982-06-15
AT351041B (de) 1979-07-10
ATA985776A (de) 1978-12-15
ZA767588B (en) 1977-11-30
HU176510B (en) 1981-03-28
GB1533020A (en) 1978-11-22
CS197301B2 (en) 1980-04-30
DE2658806A1 (de) 1977-07-14
CA1099267A (fr) 1981-04-14
NO150882B (no) 1984-09-24
JPS5283397A (en) 1977-07-12

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MM Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A