ES8900231A1 - Procedimiento para la obtencion de n-glicosilderivados de 2-amino-2-desoxi-hexosa sustituida - Google Patents
Procedimiento para la obtencion de n-glicosilderivados de 2-amino-2-desoxi-hexosa sustituidaInfo
- Publication number
- ES8900231A1 ES8900231A1 ES557729A ES557729A ES8900231A1 ES 8900231 A1 ES8900231 A1 ES 8900231A1 ES 557729 A ES557729 A ES 557729A ES 557729 A ES557729 A ES 557729A ES 8900231 A1 ES8900231 A1 ES 8900231A1
- Authority
- ES
- Spain
- Prior art keywords
- denotes hydrogen
- carbon atoms
- alkyl radical
- hydrogen
- aminoacylamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001408 amides Chemical class 0.000 title 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 title 1
- 235000013877 carbamide Nutrition 0.000 title 1
- 150000003672 ureas Chemical class 0.000 title 1
- -1 mercaptomethyl Chemical group 0.000 abstract 9
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 1
- 125000004066 1-hydroxyethyl group Chemical group [H]OC([H])([*])C([H])([H])[H] 0.000 abstract 1
- UTQNKKSJPHTPBS-UHFFFAOYSA-N 2,2,2-trichloroethanone Chemical group ClC(Cl)(Cl)[C]=O UTQNKKSJPHTPBS-UHFFFAOYSA-N 0.000 abstract 1
- 125000000143 2-carboxyethyl group Chemical group [H]OC(=O)C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000004042 4-aminobutyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- 125000003143 4-hydroxybenzyl group Chemical group [H]C([*])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Chemical group O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 1
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical group CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
LA PREPARACION DE N-GLICOSIL DERIVADOS DE 2-AMINO-2-DESOXI-HEXOSA SUSTITUIDA, DE FORMULA GENERAL (I), DONDE LOS DISTINTOS R TIENEN LOS SIGNIFICADOS DESCRITOS EN LA MEMORIA, SE LLEVA A CABO HACIENDO REACCIONAR UN COMPUESTO DE FORMULA (II) CON COMPUESTOS DE FORMULA H2N-R1, PARA OBTENER UN COMPUESTO DE FORMULA (III). A CONTINUACION DICHO COMPUESTO III SE HACE REACCIONAR CON OTRO DE FORMULA R15-CO-X-R2 PARA OBTENER UN DERIVADO DE FORMULA IV, EN EL CUAL SE LELVA A CABO LA DISOCIACION DEL GRUPO PROTECTOR R14 PARA OBTENER LA CORRESPONDIENTE FUNCION AMIDA, URETANO O UREA PROPIA DEL COMPUESTO I, HABIENDO PURIFICADO PREVIAMENTE EL COMPUESTO IV POR CROMATOGRAFIA. ESTOS COMPUESTOS PRESENTAN UN EFECTO MARCADO ACRECENTADOR DE LAS DEFENSAS Y PUEDEN EMPLEARSE A MODO DE ADYUVANTES EN MEZCLAS CON VACUNAS. *FORMULA*
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853521994 DE3521994A1 (de) | 1985-06-20 | 1985-06-20 | N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8900231A1 true ES8900231A1 (es) | 1989-04-16 |
| ES557729A0 ES557729A0 (es) | 1989-04-16 |
Family
ID=6273684
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES556287A Expired ES8801769A1 (es) | 1985-06-20 | 1986-06-19 | Procedimiento para la obtencion de n-glicosilderivados de 2-amino-2-desoxi-hexosa sustituida. |
| ES557729A Expired ES8900231A1 (es) | 1985-06-20 | 1987-09-15 | Procedimiento para la obtencion de n-glicosilderivados de 2-amino-2-desoxi-hexosa sustituida |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES556287A Expired ES8801769A1 (es) | 1985-06-20 | 1986-06-19 | Procedimiento para la obtencion de n-glicosilderivados de 2-amino-2-desoxi-hexosa sustituida. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4855283A (es) |
| EP (1) | EP0206037B1 (es) |
| JP (1) | JPH07116207B2 (es) |
| KR (1) | KR930011281B1 (es) |
| CN (1) | CN86104185A (es) |
| AT (1) | ATE71631T1 (es) |
| AU (1) | AU564222B2 (es) |
| CA (1) | CA1289952C (es) |
| CS (1) | CS270209B2 (es) |
| DE (2) | DE3521994A1 (es) |
| DK (1) | DK287886A (es) |
| ES (2) | ES8801769A1 (es) |
| FI (1) | FI84833C (es) |
| GR (1) | GR861574B (es) |
| HU (1) | HU206123B (es) |
| IE (1) | IE58918B1 (es) |
| IL (1) | IL79126A (es) |
| NO (1) | NO166002C (es) |
| PH (1) | PH26775A (es) |
| PT (1) | PT82796B (es) |
| ZA (1) | ZA864571B (es) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3812681A1 (de) * | 1988-04-16 | 1989-11-02 | Bayer Ag | Substituierte n-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US5977336A (en) * | 1993-03-16 | 1999-11-02 | St. Louis University | High molecular weight surface proteins of non-typeable haemophilus |
| EP0716658B1 (de) * | 1993-08-30 | 1997-06-04 | Bayer Ag | Glycosylamide von 2-aminoacylamino-2-desoxy-zuckern |
| US6361779B1 (en) | 1993-11-08 | 2002-03-26 | Aventis Pasteur Limited | Transferrin receptor genes |
| AU705998B2 (en) | 1993-11-08 | 1999-06-03 | Connaught Laboratories Limited | Haemophilus transferrin receptor genes |
| US6764682B1 (en) * | 1994-06-16 | 2004-07-20 | Aventis Pasteur Limited | Adjuvant compositions containing more than one adjuvant |
| US6440425B1 (en) | 1995-05-01 | 2002-08-27 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
| US6335018B1 (en) | 1995-05-01 | 2002-01-01 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
| EP0824358B1 (en) | 1995-05-04 | 2002-12-04 | Aventis Pasteur Limited | Acellular pertussis vaccines and methods of preparation thereof |
| US5827654A (en) * | 1995-05-08 | 1998-10-27 | University Of Toronto | Basal body rod protein genes of campylobacter |
| US5780606A (en) * | 1995-06-07 | 1998-07-14 | Connaught Laboratories Limited | Neisseria meningitidis capsular polysaccharide conjugates |
| US6251405B1 (en) | 1995-06-07 | 2001-06-26 | Connaught Laboratories, Inc. | Immunological combination compositions and methods |
| US6290971B1 (en) * | 1995-06-15 | 2001-09-18 | Aventis Pasteur Limited | Adjuvant compositions comprising a mineral salt and another immunostimulating compound |
| US6048539A (en) * | 1995-11-02 | 2000-04-11 | Connaught Laboratories Limited | Lactoferrin receptor protein |
| FR2746643B1 (fr) * | 1996-04-01 | 1998-06-12 | Techni Pharma | Nouvelles compositions laxatives et leur procede de fabrication |
| DK0914153T3 (da) | 1996-07-02 | 2007-01-29 | Sanofi Pasteur Ltd | Multivalente DTP-poliovacciner |
| US6042820A (en) | 1996-12-20 | 2000-03-28 | Connaught Laboratories Limited | Biodegradable copolymer containing α-hydroxy acid and α-amino acid units |
| FR2762788B1 (fr) * | 1997-04-30 | 2000-10-06 | Pasteur Merieux Serums Vacc | Composition vaccinale anti-helicobacter pour usage par voie systemique sous-diaphragmatique |
| FR2762787B1 (fr) * | 1997-04-30 | 2000-10-06 | Pasteur Merieux Serums Vacc | Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1 |
| WO1998048836A1 (fr) * | 1997-04-30 | 1998-11-05 | Merieux Oravax | Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1 |
| US5977337A (en) | 1997-06-03 | 1999-11-02 | Connaught Laboratories Limited | Lactoferrin receptor genes of Moraxella |
| US7459524B1 (en) | 1997-10-02 | 2008-12-02 | Emergent Product Development Gaithersburg Inc. | Chlamydia protein, sequence and uses thereof |
| US7785609B1 (en) | 1999-03-16 | 2010-08-31 | Sanofi Pasteur Limited | Recombinant Haemophilus influenzae adhesin proteins |
| US6335182B1 (en) | 1999-03-16 | 2002-01-01 | Aventis Pasteur Limited | Recombinant Haemophilus influenzae adhesin proteins |
| US7241449B1 (en) | 1999-04-12 | 2007-07-10 | Aventis Pasteur Limited | Transferrin receptor genes of moraxella |
| WO2001030847A1 (en) | 1999-10-22 | 2001-05-03 | Aventis Pasteur Limited | Modified gp100 and uses thereof |
| GB0000891D0 (en) * | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| PT1282702E (pt) | 2000-05-10 | 2007-02-28 | Ludwig Inst Cancer Res | Polipéptidos imunogénicos codificados por minigenes mage e suas utilizações |
| AUPS143402A0 (en) * | 2002-03-28 | 2002-05-09 | Alchemia Pty Ltd | Anomeric derivatives of monosaccharides |
| US8506959B2 (en) | 2002-11-01 | 2013-08-13 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
| TW200509968A (en) | 2002-11-01 | 2005-03-16 | Elan Pharm Inc | Prevention and treatment of synucleinopathic disease |
| AU2003293733B2 (en) * | 2002-11-26 | 2010-02-11 | Eurocine Ab | Novel amine-based adjuvant |
| JP4820291B2 (ja) | 2003-05-19 | 2011-11-24 | エラン ファーマシューティカルズ，インコーポレイテッド | レヴィー小体病におけるαシヌクレインの切断断片 |
| US7358331B2 (en) | 2003-05-19 | 2008-04-15 | Elan Pharmaceuticals, Inc. | Truncated fragments of alpha-synuclein in Lewy body disease |
| MX2007001679A (es) | 2004-08-09 | 2007-05-23 | Elan Pharm Inc | Prevencion y tratamiento de la enfermedad sinucleinopatica y amiloidogenica. |
| CN101374551B (zh) * | 2006-01-26 | 2013-06-12 | 辉瑞产品公司 | 新的糖脂佐剂组合物 |
| BRPI0706709B8 (pt) | 2006-01-26 | 2021-05-25 | Pah Usa 15 Llc | composição e processo para preparar a composição |
| PL2583978T3 (pl) | 2007-02-23 | 2016-07-29 | Prothena Biosciences Ltd Co | Profilaktyka i leczenie chorób synukleinopatycznych i amyloidogennych |
| PT2118300E (pt) | 2007-02-23 | 2015-09-22 | Univ California | Prevenção e tratamento da doença sinucleinopática e amiloidogénica |
| GB2450088A (en) * | 2007-06-11 | 2008-12-17 | Diosamine Dev Corp | Optionally modified monosaccharides with imine/iminium or glycosidic amine/ammonium group for use in modifying the level of cytokines & in therapy |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| SG186689A1 (en) | 2007-12-28 | 2013-01-30 | Univ Tennessee Res Foundation | Treatment and prophylaxis of amyloidosis |
| EP2196196A1 (en) | 2008-12-10 | 2010-06-16 | Medipol S.A. | Compound, medicament, vaccine composition and nanocapsules |
| GB201000196D0 (en) * | 2010-01-07 | 2010-02-24 | Galvez Julian M | Novel combination |
| JP6030052B2 (ja) | 2010-05-14 | 2016-11-24 | バクスアルタ インコーポレイテッド | Ｏｓｐａキメラおよびそのワクチンでの使用法 |
| CN104640563A (zh) | 2012-07-27 | 2015-05-20 | 巴克斯特国际公司 | 包含嵌合的ospa分子的组合物及其使用方法 |
| CN104628802B (zh) * | 2013-11-07 | 2017-01-18 | 北大方正集团有限公司 | 从发酵液中提取并纯化尼莫克汀的方法 |
| EP3071974A2 (en) | 2013-11-19 | 2016-09-28 | Prothena Biosciences Limited | Monitoring immunotherapy of lewy body disease from constipation symptoms |
| EP3028711A1 (en) * | 2014-12-05 | 2016-06-08 | Gubra ApS | Molecular building blocks capable of assembling carbohydrate derivatives, fatty acid residues and peptides |
| US10456459B2 (en) * | 2015-07-20 | 2019-10-29 | Zoetis Services Llc | Liposomal adjuvant compositions |
| SMT202100414T1 (it) * | 2015-07-20 | 2021-09-14 | Zoetis Services Llc | Composizioni di adiuvante liposomiale |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3213650A1 (de) * | 1982-04-14 | 1983-10-27 | Bayer Ag, 5090 Leverkusen | N-glycosylierte carbonsaeureamid-derivate, verfahren zu ihrer herstellung sowie ihre verwendung zur beeinflussung der koerpereigenen abwehr |
| DE3344257A1 (de) * | 1983-12-07 | 1985-06-13 | Bayer Ag, 5090 Leverkusen | Substituierte o-acyl-glycosylamide, verfahren zu iherer herstellung sowie ihre verwendung |
-
1985
- 1985-06-20 DE DE19853521994 patent/DE3521994A1/de not_active Withdrawn
-
1986
- 1986-06-03 NO NO862199A patent/NO166002C/no unknown
- 1986-06-05 EP EP86107665A patent/EP0206037B1/de not_active Expired - Lifetime
- 1986-06-05 AT AT86107665T patent/ATE71631T1/de not_active IP Right Cessation
- 1986-06-05 DE DE8686107665T patent/DE3683410D1/de not_active Expired - Lifetime
- 1986-06-16 US US06/874,983 patent/US4855283A/en not_active Expired - Lifetime
- 1986-06-17 IL IL79126A patent/IL79126A/xx not_active IP Right Cessation
- 1986-06-18 CA CA000511894A patent/CA1289952C/en not_active Expired - Lifetime
- 1986-06-18 AU AU58979/86A patent/AU564222B2/en not_active Expired
- 1986-06-18 GR GR861574A patent/GR861574B/el unknown
- 1986-06-18 CS CS864513A patent/CS270209B2/cs unknown
- 1986-06-18 FI FI862619A patent/FI84833C/fi not_active IP Right Cessation
- 1986-06-18 PH PH33904A patent/PH26775A/en unknown
- 1986-06-18 JP JP61140434A patent/JPH07116207B2/ja not_active Expired - Lifetime
- 1986-06-19 ES ES556287A patent/ES8801769A1/es not_active Expired
- 1986-06-19 HU HU862584A patent/HU206123B/hu unknown
- 1986-06-19 DK DK287886A patent/DK287886A/da not_active Application Discontinuation
- 1986-06-19 KR KR8604878A patent/KR930011281B1/ko not_active IP Right Cessation
- 1986-06-19 ZA ZA864571A patent/ZA864571B/xx unknown
- 1986-06-19 PT PT82796A patent/PT82796B/pt not_active IP Right Cessation
- 1986-06-19 IE IE163686A patent/IE58918B1/en not_active IP Right Cessation
- 1986-06-20 CN CN198686104185A patent/CN86104185A/zh active Pending
-
1987
- 1987-09-15 ES ES557729A patent/ES8900231A1/es not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8801769A1 (es) | Procedimiento para la obtencion de n-glicosilderivados de 2-amino-2-desoxi-hexosa sustituida. | |
| MX9203744A (es) | Analogos de camptotecina solubles en agua utiles para inhibir el crecimiento de celulas de tumor de animal. | |
| ES8200645A1 (es) | Un procedimiento para la preparacion de un muramildipeptido. | |
| MY106314A (en) | New tetrazole derivatives, process for their preparation and their use | |
| DE3269422D1 (en) | Pharmaceutical amides, and preparation, formulations and use thereof | |
| ZA853830B (en) | New cephalosporins and processes for their preparation | |
| ES8500219A1 (es) | Procedimiento para preparar un hexapeptido ciclico | |
| AU6368690A (en) | Intermediates for use in the synthesis of peptide amides by means of a solid phase method using acid-labile anchoring groups | |
| DE3360881D1 (en) | Benzhydrylsulfinyl ethyl amines, process for their preparation and their use in therapy | |
| DK0609310T3 (da) | N-(mercaptoacyl)aminosyrer, fremgangsmåder til fremstilling og terapeutisk anvendelse deraf og farmaceutiske sammensætninge | |
| ES485828A1 (es) | Procedimiento para la preparacion de piridazinas substitui- das | |
| DE3361670D1 (en) | N-substituted imidazole derivatives, their preparation, pharmaceutical compositions containing them and their use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |