ES8707715A1 - Un preocedimiento para producir acidos 5-florunicotinicos - Google Patents
Un preocedimiento para producir acidos 5-florunicotinicosInfo
- Publication number
- ES8707715A1 ES8707715A1 ES557078A ES557078A ES8707715A1 ES 8707715 A1 ES8707715 A1 ES 8707715A1 ES 557078 A ES557078 A ES 557078A ES 557078 A ES557078 A ES 557078A ES 8707715 A1 ES8707715 A1 ES 8707715A1
- Authority
- ES
- Spain
- Prior art keywords
- opt
- prodn
- protecting
- naphthyridine
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 formamide acetal Chemical class 0.000 abstract 5
- 239000000543 intermediate Substances 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FLBAYUMRQUHISI-UHFFFAOYSA-N 1,8-naphthyridine Chemical compound N1=CC=CC2=CC=CN=C21 FLBAYUMRQUHISI-UHFFFAOYSA-N 0.000 abstract 1
- UJHBRXADHIQCLJ-UHFFFAOYSA-N 3-oxo-3-pyridin-3-ylpropanoic acid Chemical compound OC(=O)CC(=O)C1=CC=CN=C1 UJHBRXADHIQCLJ-UHFFFAOYSA-N 0.000 abstract 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- ZHNUHDYFZUAESO-UHFFFAOYSA-N formamide Substances NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
METODO DE PRODUCIR ACIDOS 5-FLUORNICOTINICOS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN AGUA O BENCENO, EN PRESENCIA DE METOXIDO SODICO, ENTRE 0 Y 150JC Y DURANTE 5 MIUNUTOS A 30 HORAS, PARA OBTENER UN COMPUESTO DE FORMULA (I) O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO, SIENDO: R1 H O UN PROTECTOR DE CARBOXILO; X H O F; Y Z UN GRUPO SEPARABLE COMO HIDROXILO, HALOGENO O ALCANOSULFONILOXI. SE UTILIZAN COMO ANTIBACTERIALES.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60009191A JPH0629247B2 (ja) | 1985-01-23 | 1985-01-23 | ５−フルオロニコチン酸誘導体およびその塩 |
| JP60028397A JPH0629246B2 (ja) | 1985-02-18 | 1985-02-18 | ２−（５−フルオロニコチノイル）酢酸誘導体およびその塩 |
| JP60043644A JPH0665670B2 (ja) | 1985-03-07 | 1985-03-07 | １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩 |
| JP60069061A JPH0665671B2 (ja) | 1985-04-03 | 1985-04-03 | １−置換アリ−ル−１，４−ジヒドロ−４−オキソナフチリジン誘導体またはその塩の新規製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8707715A1 true ES8707715A1 (es) | 1987-08-16 |
| ES557078A0 ES557078A0 (es) | 1987-08-16 |
Family
ID=27455116
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES551134A Expired ES8702362A1 (es) | 1985-01-23 | 1986-01-22 | Un procedimiento para producir un derivado de 1,4-dihidro-4-oxo-naftiridina |
| ES557077A Expired ES8707730A1 (es) | 1985-01-23 | 1986-09-19 | Un precedimiento para producir un derivado de 1,4-dihidro-4-oxo-naftiridina |
| ES557078A Expired ES8707715A1 (es) | 1985-01-23 | 1986-09-19 | Un preocedimiento para producir acidos 5-florunicotinicos |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES551134A Expired ES8702362A1 (es) | 1985-01-23 | 1986-01-22 | Un procedimiento para producir un derivado de 1,4-dihidro-4-oxo-naftiridina |
| ES557077A Expired ES8707730A1 (es) | 1985-01-23 | 1986-09-19 | Un precedimiento para producir un derivado de 1,4-dihidro-4-oxo-naftiridina |
Country Status (1)
| Country | Link |
|---|---|
| ES (3) | ES8702362A1 (es) |
-
1986
- 1986-01-22 ES ES551134A patent/ES8702362A1/es not_active Expired
- 1986-09-19 ES ES557077A patent/ES8707730A1/es not_active Expired
- 1986-09-19 ES ES557078A patent/ES8707715A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES551134A0 (es) | 1986-12-16 |
| ES8707730A1 (es) | 1987-08-16 |
| ES557077A0 (es) | 1987-08-16 |
| ES8702362A1 (es) | 1986-12-16 |
| ES557078A0 (es) | 1987-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20070609 |