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ES8609470A1 - Procedimiento para la inmovilizacion de celulas de bacillus subtilis - Google Patents

Procedimiento para la inmovilizacion de celulas de bacillus subtilis

Info

Publication number
ES8609470A1
ES8609470A1 ES546542A ES546542A ES8609470A1 ES 8609470 A1 ES8609470 A1 ES 8609470A1 ES 546542 A ES546542 A ES 546542A ES 546542 A ES546542 A ES 546542A ES 8609470 A1 ES8609470 A1 ES 8609470A1
Authority
ES
Spain
Prior art keywords
beta
acids
bacillus subtilis
cepholosporan
acylamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546542A
Other languages
English (en)
Other versions
ES546542A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8609470A1 publication Critical patent/ES8609470A1/es
Publication of ES546542A0 publication Critical patent/ES546542A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/098—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer formed in the presence of the enzymes or microbial cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

METODO DE TRANSFORMACION DE ACIDOS 7-B-ACILAMIDO-CEFALOSPORANICOS PROTEGIDOS REVERSIBLEMENTE EN ACIDOS 7-B-ACILAMIDO-3-HIDROXIMETIL-CEF-3-EM-4-CARBOXILICOS. CONSISTE EN LLEVAR A CABO DICHA TRANSFORMACION EN UN INTERVALO DE PH COMPRENDIDO ENTRE 6 Y 8, CON CELULAS DE BACILLUS SUBTILIS INMOVILIZADAS, MEDIANTE COMBINACION DE UNA SUSPENSION DE LAS MISMAS, PARA SU PRECIPITACION Y FIJACION, CON EL AGENTE PRECIPITANTE TANINO, CON POLIETILENIMINA Y CON BETZ 11800, ASI COMO CON EL RETICULANTE TRANSVERSAL GLUTARDIALDEHIDO. LA TRANSFORMACION SE LLEVA A CABO A UNA CONCENTRACION DE LOS SUSTRATOS DE 1 A 20%, A UNA TEMPERATURA COMPRENDIDA ENTRE 20JC Y 40JC. ESTOS COMPUESTOS TIENEN APLICACIONES PARA PRODUCIR CEFALOSPORINAS SEMISINTETICAS.
ES546542A 1984-08-31 1985-08-29 Procedimiento para la inmovilizacion de celulas de bacillus subtilis Expired ES8609470A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843432060 DE3432060A1 (de) 1984-08-31 1984-08-31 Immobilisierte zellen von bacillus subtilis, immobilisierungsverfahren und verwendung des praeparats zur abspaltung der 3-acetoxygruppe aus 7-ss-acylamido-cephalosporansaeuren

Publications (2)

Publication Number Publication Date
ES8609470A1 true ES8609470A1 (es) 1986-07-16
ES546542A0 ES546542A0 (es) 1986-07-16

Family

ID=6244370

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546542A Expired ES8609470A1 (es) 1984-08-31 1985-08-29 Procedimiento para la inmovilizacion de celulas de bacillus subtilis

Country Status (5)

Country Link
EP (1) EP0173206A1 (es)
JP (1) JPS6167489A (es)
DE (1) DE3432060A1 (es)
DK (1) DK398085A (es)
ES (1) ES8609470A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2040707C (en) * 1990-04-27 2002-07-09 Kenji Mitsushima Cephalosporin acetylhydrolase gene and protein encoded by said gene
JPH088877B2 (ja) * 1990-06-19 1996-01-31 塩野義製薬株式会社 デアセチル―７―アミノセファロスポラン酸の製造法
US5512454A (en) * 1994-02-03 1996-04-30 Bristol-Myers Squibb Company Enzymatic acylation of 3-hydroxymethyl cephalosporins
NO301445B1 (no) * 1994-07-13 1997-10-27 Petroleum Geo Services As Anordning for sleping

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1474519A (es) * 1973-05-14 1977-05-25
DE2355078A1 (de) * 1973-11-03 1975-05-07 Bayer Ag Verfahren zur herstellung von 7-amino-delta hoch 3-cephem-derivaten
AT378003B (de) * 1979-07-19 1985-06-10 Glaxo Group Ltd Verfahren zur herstellung von desactylcephalosporin c
US4337313A (en) * 1980-12-08 1982-06-29 Miles Laboratories, Inc. Immobilization of biocatalysts
US4390627A (en) * 1981-10-26 1983-06-28 Miles Laboratories, Inc. Immobilization of the sucrose mutase in whole cells of protaminobacter rubrum

Also Published As

Publication number Publication date
DK398085A (da) 1986-03-01
JPS6167489A (ja) 1986-04-07
EP0173206A1 (de) 1986-03-05
DK398085D0 (da) 1985-08-30
ES546542A0 (es) 1986-07-16
DE3432060A1 (de) 1986-03-06

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