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ES8608862A1 - Un procedimiento para estabilizar particulas micelares y aumentar su duracion en estado preparado. - Google Patents

Un procedimiento para estabilizar particulas micelares y aumentar su duracion en estado preparado.

Info

Publication number
ES8608862A1
ES8608862A1 ES543495A ES543495A ES8608862A1 ES 8608862 A1 ES8608862 A1 ES 8608862A1 ES 543495 A ES543495 A ES 543495A ES 543495 A ES543495 A ES 543495A ES 8608862 A1 ES8608862 A1 ES 8608862A1
Authority
ES
Spain
Prior art keywords
micelles
protective
gel matrix
gel
vesicle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543495A
Other languages
English (en)
Other versions
ES543495A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexstar Pharmaceuticals Inc
Original Assignee
Vestar Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Research Inc filed Critical Vestar Research Inc
Publication of ES543495A0 publication Critical patent/ES543495A0/es
Publication of ES8608862A1 publication Critical patent/ES8608862A1/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1227Micelles, e.g. phospholipidic or polymeric micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Colloid Chemistry (AREA)
  • Luminescent Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Ceramic Products (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

PROCEDIMIENTO PARA LA ESTABILIZACION DE PARTICULAS MICELARES Y PARA AUMENTAR SU DURACION EN ESTADO PREPARADO. CONSISTE EN SUSPENDER LAS PARTICULAS EN UNA MATRIZ DE GEL POLIMERA PARA FORMAR UNA SUPERFICIE DE GEL PROTECTORA ALREDEDOR DE DICHAS PARTICULAS, SIENDO DICHA MATRIZ CAPAZ DE TRANSFORMARSE EN UN FLUIDO, TRANSFORMANDO LA SUPERFICIE DE GEL PROTECTORA EN UNA SUSPENSION ACUOSA. EL TAMAÑO Y PROPIEDADES DE LAS PARTICULAS MICERALES PERMANECEN CON EL MISMO TAMAÑO A LO LARGO DEL ALMACENAMIENTO, MIENTRAS EL GEL PERMANEZCA EN SU ESTADO SOLIDO. SIN EMBARGO, A TEMPERATURA AMBIENTE O SUPERIOR, EL GEL SE FUNDE Y LA VESICULA U OTRA PARTICULA CUALQUIERA VUELVE A SU FORMA ORIGINAL EN SUSPENSION EN UN MEDIO ACUOSO. DE APLICACION COMO PORTADORES PARA AGENTES FARMACEUTICAS.
ES543495A 1984-05-25 1985-05-24 Un procedimiento para estabilizar particulas micelares y aumentar su duracion en estado preparado. Expired ES8608862A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61425584A 1984-05-25 1984-05-25

Publications (2)

Publication Number Publication Date
ES543495A0 ES543495A0 (es) 1986-09-01
ES8608862A1 true ES8608862A1 (es) 1986-09-01

Family

ID=24460474

Family Applications (1)

Application Number Title Priority Date Filing Date
ES543495A Expired ES8608862A1 (es) 1984-05-25 1985-05-24 Un procedimiento para estabilizar particulas micelares y aumentar su duracion en estado preparado.

Country Status (13)

Country Link
EP (1) EP0162724B1 (es)
JP (1) JPH0696515B2 (es)
KR (1) KR850008450A (es)
AT (1) ATE93387T1 (es)
AU (1) AU576363B2 (es)
CA (1) CA1263311A (es)
DE (1) DE3587541T2 (es)
DK (1) DK164483C (es)
ES (1) ES8608862A1 (es)
HU (1) HU200698B (es)
IE (1) IE61706B1 (es)
IL (1) IL75315A (es)
ZA (1) ZA853943B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708861A (en) * 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
US4740375A (en) * 1985-02-25 1988-04-26 Technology Unlimited, Inc. Gelcores
EP0199362A3 (en) * 1985-04-26 1987-10-07 Massachusetts Institute Of Technology System and apparatus for delayed and pulsed release of biologically active substances
GB8522963D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Microcapsules
US4839111A (en) * 1987-02-02 1989-06-13 The University Of Tennessee Research Corporation Preparation of solid core liposomes
FR2620333B1 (fr) * 1987-09-15 1990-01-05 Inst Nat Sante Rech Med Liposomes, leur procede de preparation et application desdits liposomes comme vecteur de produits
US5006473A (en) * 1988-08-09 1991-04-09 Abbott Laboratories Electrophoresis method using vesicles
US5064655A (en) * 1989-02-24 1991-11-12 Liposome Technology, Inc. Liposome gel composition and method
CA2229068A1 (en) * 1995-08-10 1997-02-20 Masao Kato Block polymer having functional groups on its both ends
US5962015A (en) * 1997-05-02 1999-10-05 Kobo Products S.A.R.L. Stabilized liposomes
FR2764507B1 (fr) * 1997-06-11 2000-10-20 Lipogel Sarl Compositions pulverulentes de liposomes unilamellaires, leur procede de preparation et leurs applications comme complements nutritionnels et comme complements nutritionnels et comme medicaments
US6048546A (en) * 1997-07-31 2000-04-11 Sandia Corporation Immobilized lipid-bilayer materials
WO2000076476A1 (en) * 1999-06-11 2000-12-21 Endorex Corporation Adjuvant-containing polymerized liposomes for oral, mucosal or intranasal vaccination
US20050129751A1 (en) * 2003-12-16 2005-06-16 Rothenberg Barry E. Drug delivery compositions and methods
PL2066310T3 (pl) * 2006-09-22 2012-09-28 Mivital Ag Emulsje zawierające gumę arabską
US20110020428A1 (en) * 2007-11-15 2011-01-27 Qun Zeng Gel-stabilized liposome compositions, methods for their preparation and uses thereof
BRPI0915271A2 (pt) * 2008-11-14 2016-06-14 Archer Daniels Midland Co composição de organo-gel fosfolipídico estruturado termorreversível, uso da composição de organo-gel fosfolipídico estruturado termorreversível, processo para a obtenção de um produto cristalino líquido e método de carregar organo-gel fosfolipídico estruturado termorreversível
FR2943252B1 (fr) * 2009-03-17 2011-08-05 Dermo Cosmetique Animale Lab De Composition dermo-cosmetique
MX339957B (es) * 2010-05-14 2016-06-20 Archer Daniels Midland Co Composiciones alimenticias que comprenden organogeles.
JP2012102043A (ja) * 2010-11-10 2012-05-31 Konica Minolta Holdings Inc 単胞リポソームの製造方法、単胞リポソームの分散液とその乾燥粉末及びそれらの製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3269611D1 (en) * 1981-07-02 1986-04-10 Hoffmann La Roche Process for preparing liposome solutions
GB2135647A (en) * 1983-02-15 1984-09-05 Squibb & Sons Inc Method of preparing liposomes and products produced thereby
US4608278A (en) * 1983-06-22 1986-08-26 The Ohio State University Research Foundation Small particule formation and encapsulation
FR2548902B1 (fr) * 1983-07-13 1986-04-11 Guerbet Sa Gel pour embolisation therapeutique
US4708861A (en) * 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions

Also Published As

Publication number Publication date
DE3587541D1 (de) 1993-09-30
ZA853943B (en) 1988-12-28
CA1263311A (en) 1989-11-28
DK234185A (da) 1985-11-26
ATE93387T1 (de) 1993-09-15
DE3587541T2 (de) 1993-12-23
ES543495A0 (es) 1986-09-01
IL75315A0 (en) 1985-09-29
DK164483C (da) 1992-11-16
JPS60258109A (ja) 1985-12-20
AU4285685A (en) 1985-12-12
EP0162724A3 (en) 1986-07-23
IE61706B1 (en) 1994-11-30
EP0162724A2 (en) 1985-11-27
DK234185D0 (da) 1985-05-24
HU200698B (en) 1990-08-28
AU576363B2 (en) 1988-08-25
KR850008450A (ko) 1985-12-18
EP0162724B1 (en) 1993-08-25
DK164483B (da) 1992-07-06
HUT38266A (en) 1986-05-28
IE851306L (en) 1985-11-25
JPH0696515B2 (ja) 1994-11-30
IL75315A (en) 1991-07-18

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20000401