ES8608862A1 - Un procedimiento para estabilizar particulas micelares y aumentar su duracion en estado preparado. - Google Patents
Un procedimiento para estabilizar particulas micelares y aumentar su duracion en estado preparado.Info
- Publication number
- ES8608862A1 ES8608862A1 ES543495A ES543495A ES8608862A1 ES 8608862 A1 ES8608862 A1 ES 8608862A1 ES 543495 A ES543495 A ES 543495A ES 543495 A ES543495 A ES 543495A ES 8608862 A1 ES8608862 A1 ES 8608862A1
- Authority
- ES
- Spain
- Prior art keywords
- micelles
- protective
- gel matrix
- gel
- vesicle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
- 239000000693 micelle Substances 0.000 abstract 3
- 239000011159 matrix material Substances 0.000 abstract 2
- 230000001681 protective effect Effects 0.000 abstract 2
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
- A61K51/1227—Micelles, e.g. phospholipidic or polymeric micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
- A61K51/1234—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Colloid Chemistry (AREA)
- Luminescent Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Signal Processing For Digital Recording And Reproducing (AREA)
- Ceramic Products (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
PROCEDIMIENTO PARA LA ESTABILIZACION DE PARTICULAS MICELARES Y PARA AUMENTAR SU DURACION EN ESTADO PREPARADO. CONSISTE EN SUSPENDER LAS PARTICULAS EN UNA MATRIZ DE GEL POLIMERA PARA FORMAR UNA SUPERFICIE DE GEL PROTECTORA ALREDEDOR DE DICHAS PARTICULAS, SIENDO DICHA MATRIZ CAPAZ DE TRANSFORMARSE EN UN FLUIDO, TRANSFORMANDO LA SUPERFICIE DE GEL PROTECTORA EN UNA SUSPENSION ACUOSA. EL TAMAÑO Y PROPIEDADES DE LAS PARTICULAS MICERALES PERMANECEN CON EL MISMO TAMAÑO A LO LARGO DEL ALMACENAMIENTO, MIENTRAS EL GEL PERMANEZCA EN SU ESTADO SOLIDO. SIN EMBARGO, A TEMPERATURA AMBIENTE O SUPERIOR, EL GEL SE FUNDE Y LA VESICULA U OTRA PARTICULA CUALQUIERA VUELVE A SU FORMA ORIGINAL EN SUSPENSION EN UN MEDIO ACUOSO. DE APLICACION COMO PORTADORES PARA AGENTES FARMACEUTICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61425584A | 1984-05-25 | 1984-05-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES543495A0 ES543495A0 (es) | 1986-09-01 |
ES8608862A1 true ES8608862A1 (es) | 1986-09-01 |
Family
ID=24460474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543495A Expired ES8608862A1 (es) | 1984-05-25 | 1985-05-24 | Un procedimiento para estabilizar particulas micelares y aumentar su duracion en estado preparado. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0162724B1 (es) |
JP (1) | JPH0696515B2 (es) |
KR (1) | KR850008450A (es) |
AT (1) | ATE93387T1 (es) |
AU (1) | AU576363B2 (es) |
CA (1) | CA1263311A (es) |
DE (1) | DE3587541T2 (es) |
DK (1) | DK164483C (es) |
ES (1) | ES8608862A1 (es) |
HU (1) | HU200698B (es) |
IE (1) | IE61706B1 (es) |
IL (1) | IL75315A (es) |
ZA (1) | ZA853943B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4708861A (en) * | 1984-02-15 | 1987-11-24 | The Liposome Company, Inc. | Liposome-gel compositions |
US4740375A (en) * | 1985-02-25 | 1988-04-26 | Technology Unlimited, Inc. | Gelcores |
EP0199362A3 (en) * | 1985-04-26 | 1987-10-07 | Massachusetts Institute Of Technology | System and apparatus for delayed and pulsed release of biologically active substances |
GB8522963D0 (en) * | 1985-09-17 | 1985-10-23 | Biocompatibles Ltd | Microcapsules |
US4839111A (en) * | 1987-02-02 | 1989-06-13 | The University Of Tennessee Research Corporation | Preparation of solid core liposomes |
FR2620333B1 (fr) * | 1987-09-15 | 1990-01-05 | Inst Nat Sante Rech Med | Liposomes, leur procede de preparation et application desdits liposomes comme vecteur de produits |
US5006473A (en) * | 1988-08-09 | 1991-04-09 | Abbott Laboratories | Electrophoresis method using vesicles |
US5064655A (en) * | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
CA2229068A1 (en) * | 1995-08-10 | 1997-02-20 | Masao Kato | Block polymer having functional groups on its both ends |
US5962015A (en) * | 1997-05-02 | 1999-10-05 | Kobo Products S.A.R.L. | Stabilized liposomes |
FR2764507B1 (fr) * | 1997-06-11 | 2000-10-20 | Lipogel Sarl | Compositions pulverulentes de liposomes unilamellaires, leur procede de preparation et leurs applications comme complements nutritionnels et comme complements nutritionnels et comme medicaments |
US6048546A (en) * | 1997-07-31 | 2000-04-11 | Sandia Corporation | Immobilized lipid-bilayer materials |
WO2000076476A1 (en) * | 1999-06-11 | 2000-12-21 | Endorex Corporation | Adjuvant-containing polymerized liposomes for oral, mucosal or intranasal vaccination |
US20050129751A1 (en) * | 2003-12-16 | 2005-06-16 | Rothenberg Barry E. | Drug delivery compositions and methods |
PL2066310T3 (pl) * | 2006-09-22 | 2012-09-28 | Mivital Ag | Emulsje zawierające gumę arabską |
US20110020428A1 (en) * | 2007-11-15 | 2011-01-27 | Qun Zeng | Gel-stabilized liposome compositions, methods for their preparation and uses thereof |
BRPI0915271A2 (pt) * | 2008-11-14 | 2016-06-14 | Archer Daniels Midland Co | composição de organo-gel fosfolipídico estruturado termorreversível, uso da composição de organo-gel fosfolipídico estruturado termorreversível, processo para a obtenção de um produto cristalino líquido e método de carregar organo-gel fosfolipídico estruturado termorreversível |
FR2943252B1 (fr) * | 2009-03-17 | 2011-08-05 | Dermo Cosmetique Animale Lab De | Composition dermo-cosmetique |
MX339957B (es) * | 2010-05-14 | 2016-06-20 | Archer Daniels Midland Co | Composiciones alimenticias que comprenden organogeles. |
JP2012102043A (ja) * | 2010-11-10 | 2012-05-31 | Konica Minolta Holdings Inc | 単胞リポソームの製造方法、単胞リポソームの分散液とその乾燥粉末及びそれらの製造方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3269611D1 (en) * | 1981-07-02 | 1986-04-10 | Hoffmann La Roche | Process for preparing liposome solutions |
GB2135647A (en) * | 1983-02-15 | 1984-09-05 | Squibb & Sons Inc | Method of preparing liposomes and products produced thereby |
US4608278A (en) * | 1983-06-22 | 1986-08-26 | The Ohio State University Research Foundation | Small particule formation and encapsulation |
FR2548902B1 (fr) * | 1983-07-13 | 1986-04-11 | Guerbet Sa | Gel pour embolisation therapeutique |
US4708861A (en) * | 1984-02-15 | 1987-11-24 | The Liposome Company, Inc. | Liposome-gel compositions |
-
1985
- 1985-05-24 JP JP60111974A patent/JPH0696515B2/ja not_active Expired - Lifetime
- 1985-05-24 DE DE85303676T patent/DE3587541T2/de not_active Expired - Fee Related
- 1985-05-24 EP EP85303676A patent/EP0162724B1/en not_active Expired - Lifetime
- 1985-05-24 CA CA000482261A patent/CA1263311A/en not_active Expired
- 1985-05-24 DK DK234185A patent/DK164483C/da active
- 1985-05-24 HU HU851987A patent/HU200698B/hu not_active IP Right Cessation
- 1985-05-24 IE IE130685A patent/IE61706B1/en not_active IP Right Cessation
- 1985-05-24 ES ES543495A patent/ES8608862A1/es not_active Expired
- 1985-05-24 AT AT85303676T patent/ATE93387T1/de active
- 1985-05-24 AU AU42856/85A patent/AU576363B2/en not_active Ceased
- 1985-05-24 ZA ZA853943A patent/ZA853943B/xx unknown
- 1985-05-24 IL IL75315A patent/IL75315A/xx not_active IP Right Cessation
- 1985-05-25 KR KR1019850003629A patent/KR850008450A/ko not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
DE3587541D1 (de) | 1993-09-30 |
ZA853943B (en) | 1988-12-28 |
CA1263311A (en) | 1989-11-28 |
DK234185A (da) | 1985-11-26 |
ATE93387T1 (de) | 1993-09-15 |
DE3587541T2 (de) | 1993-12-23 |
ES543495A0 (es) | 1986-09-01 |
IL75315A0 (en) | 1985-09-29 |
DK164483C (da) | 1992-11-16 |
JPS60258109A (ja) | 1985-12-20 |
AU4285685A (en) | 1985-12-12 |
EP0162724A3 (en) | 1986-07-23 |
IE61706B1 (en) | 1994-11-30 |
EP0162724A2 (en) | 1985-11-27 |
DK234185D0 (da) | 1985-05-24 |
HU200698B (en) | 1990-08-28 |
AU576363B2 (en) | 1988-08-25 |
KR850008450A (ko) | 1985-12-18 |
EP0162724B1 (en) | 1993-08-25 |
DK164483B (da) | 1992-07-06 |
HUT38266A (en) | 1986-05-28 |
IE851306L (en) | 1985-11-25 |
JPH0696515B2 (ja) | 1994-11-30 |
IL75315A (en) | 1991-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted | ||
FD1A | Patent lapsed |
Effective date: 20000401 |