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ES8600236A1 - PROCEDURE FOR THE PREPARATION OF NEW HETERO-CYCLIC ESTERS OF ACETIC ACID. - Google Patents

PROCEDURE FOR THE PREPARATION OF NEW HETERO-CYCLIC ESTERS OF ACETIC ACID.

Info

Publication number
ES8600236A1
ES8600236A1 ES533664A ES533664A ES8600236A1 ES 8600236 A1 ES8600236 A1 ES 8600236A1 ES 533664 A ES533664 A ES 533664A ES 533664 A ES533664 A ES 533664A ES 8600236 A1 ES8600236 A1 ES 8600236A1
Authority
ES
Spain
Prior art keywords
preparation
procedure
acetic acid
cyclic esters
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533664A
Other languages
Spanish (es)
Other versions
ES533664A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Biogal Gyogyszergyar Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT, Biogal Gyogyszergyar Rt filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES533664A0 publication Critical patent/ES533664A0/en
Publication of ES8600236A1 publication Critical patent/ES8600236A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DIASTEREOISOMEROS, DE FORMULA GENERAL (I).COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, DE UN COMPUESTO DE FORMULA GENERAL (II) SE SEPARA EL GRUPO CETAL ETILENICO; SEGUNDA, EL COMPUESTO DE FORMULA GENERAL (II) OBTENIDO EN LA REACCION ANTERIOR SE SOMETE A UN PROCESO DE REDUCCION; Y POR ULTIMO, SE AISLA EL PRODUCTO ASI OBTENIDO.DE APLICACION COMO PRODUCTOS INTERMEDIOS EN LA PREPARACION DE TIENAMICINA, QUEA SU VEZ SE UTILIZA EN MEDICINA COMO ANTIBIOTICO.PROCEDURE FOR THE PREPARATION OF DIASTEREOISOMERS, OF GENERAL FORMULA (I). INCLUDES THE FOLLOWING OPERATIONS: FIRST, FROM A COMPOUND OF GENERAL FORMULA (II) THE ETHYLENE KETAL GROUP IS SEPARATED; SECOND, THE COMPOUND OF GENERAL FORMULA (II) OBTAINED IN THE PREVIOUS REACTION IS SUBJECTED TO A REDUCTION PROCESS; AND FINALLY, THE PRODUCT SO OBTAINED IS ISOLATED. FROM APPLICATION AS INTERMEDIATE PRODUCTS IN THE PREPARATION OF THIENAMYCIN, WHICH IN TURN IS USED IN MEDICINE AS AN ANTIBIOTIC.

ES533664A 1983-06-23 1984-06-22 PROCEDURE FOR THE PREPARATION OF NEW HETERO-CYCLIC ESTERS OF ACETIC ACID. Expired ES8600236A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU832218A HU188913B (en) 1983-06-23 1983-06-23 Process for producing new azetidinyl-acetic acid esters

Publications (2)

Publication Number Publication Date
ES533664A0 ES533664A0 (en) 1985-10-01
ES8600236A1 true ES8600236A1 (en) 1985-10-01

Family

ID=10958351

Family Applications (1)

Application Number Title Priority Date Filing Date
ES533664A Expired ES8600236A1 (en) 1983-06-23 1984-06-22 PROCEDURE FOR THE PREPARATION OF NEW HETERO-CYCLIC ESTERS OF ACETIC ACID.

Country Status (19)

Country Link
JP (1) JPS6056955A (en)
AT (1) AT383118B (en)
AU (1) AU560544B2 (en)
BE (1) BE899936A (en)
CA (1) CA1215715A (en)
CH (1) CH661269A5 (en)
DE (1) DE3423069A1 (en)
ES (1) ES8600236A1 (en)
FI (1) FI842515L (en)
FR (1) FR2549052B1 (en)
GB (1) GB2144120B (en)
GR (1) GR81634B (en)
HU (1) HU188913B (en)
IT (1) IT1196155B (en)
LU (1) LU85424A1 (en)
NL (1) NL8401978A (en)
PL (1) PL142079B1 (en)
SE (1) SE8403349L (en)
ZA (1) ZA844724B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59222696A (en) * 1983-05-31 1984-12-14 ハウス食品工業株式会社 Method and device for discharging drain
HU193323B (en) * 1985-03-27 1987-09-28 Richter Gedeon Vegyeszet Process for preparing azetidinone derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS604814B2 (en) * 1978-03-03 1985-02-06 協和醗酵工業株式会社 2-azetidinone derivative and method for producing the same
PT71553B (en) * 1979-07-23 1981-12-14 Merck & Co Inc Process for the preparation of thienamycin and intermediates
US4287123A (en) * 1980-01-14 1981-09-01 Merck & Co., Inc. Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate
JPS57167964A (en) * 1981-04-09 1982-10-16 Toyama Chem Co Ltd Preparation of (4r)-3-substituted-4-(substituted or unsubstituted carboxymethyl)-2-azetidinone derivative

Also Published As

Publication number Publication date
ZA844724B (en) 1985-02-27
HUT34441A (en) 1985-03-28
HU188913B (en) 1986-05-28
SE8403349L (en) 1984-12-24
SE8403349D0 (en) 1984-06-21
FR2549052A1 (en) 1985-01-18
FR2549052B1 (en) 1987-12-04
CH661269A5 (en) 1987-07-15
PL142079B1 (en) 1987-09-30
GR81634B (en) 1984-12-11
NL8401978A (en) 1985-01-16
GB2144120A (en) 1985-02-27
JPS6056955A (en) 1985-04-02
LU85424A1 (en) 1986-02-18
CA1215715A (en) 1986-12-23
ATA202784A (en) 1986-10-15
PL248312A1 (en) 1985-07-16
FI842515A7 (en) 1984-12-24
AU560544B2 (en) 1987-04-09
ES533664A0 (en) 1985-10-01
DE3423069A1 (en) 1985-01-10
IT8421534A1 (en) 1985-12-21
FI842515A0 (en) 1984-06-21
AT383118B (en) 1987-05-25
IT1196155B (en) 1988-11-10
IT8421534A0 (en) 1984-06-21
GB2144120B (en) 1987-01-21
FI842515L (en) 1984-12-24
BE899936A (en) 1984-10-15
GB8415800D0 (en) 1984-07-25
AU2974584A (en) 1985-01-03

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