[go: up one dir, main page]

ES8500287A1 - Nuevos derivados de 19-tioandrostano - Google Patents

Nuevos derivados de 19-tioandrostano

Info

Publication number
ES8500287A1
ES8500287A1 ES524096A ES524096A ES8500287A1 ES 8500287 A1 ES8500287 A1 ES 8500287A1 ES 524096 A ES524096 A ES 524096A ES 524096 A ES524096 A ES 524096A ES 8500287 A1 ES8500287 A1 ES 8500287A1
Authority
ES
Spain
Prior art keywords
novel
thio
hydrocarbyl
androstane derivatives
aromatase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524096A
Other languages
English (en)
Other versions
ES524096A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of ES524096A0 publication Critical patent/ES524096A0/es
Publication of ES8500287A1 publication Critical patent/ES8500287A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 19-TIOANDROSTANO, DE FORMULA GENERAL (I) Y SUS 4,5-DIHIDRO-ANALOGOS.CONSISTE EN HACER REACCIONAR EL 19-SULFONATO CORRESPONDIENTE O EL 19-HALO-DERIVADO CON ESTRUCTURA 3-OXO-Q4 O 3-HIDROXI-Q5, CON UNA SAL METALICA DE UN TIOL O DE UN ACIDO TIOCARBOXILICO.DE APLICACION EN LA OBTENCION DE PREPARADOS FARMACEUTICOS POR SUS PROPIEDADES INHIBIDORAS DE LA AROMATASA.
ES524096A 1982-07-14 1983-07-13 Nuevos derivados de 19-tioandrostano Expired ES8500287A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8202841 1982-07-14

Publications (2)

Publication Number Publication Date
ES524096A0 ES524096A0 (es) 1984-10-01
ES8500287A1 true ES8500287A1 (es) 1984-10-01

Family

ID=19840027

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524096A Expired ES8500287A1 (es) 1982-07-14 1983-07-13 Nuevos derivados de 19-tioandrostano

Country Status (12)

Country Link
EP (1) EP0100566B1 (es)
JP (1) JPS5931800A (es)
KR (1) KR840005465A (es)
AU (1) AU555982B2 (es)
CA (1) CA1199023A (es)
DE (1) DE3362176D1 (es)
DK (1) DK323083A (es)
ES (1) ES8500287A1 (es)
FI (1) FI78710C (es)
HU (1) HU188923B (es)
IE (1) IE55077B1 (es)
ZA (1) ZA834726B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3121152A1 (de) * 1981-05-22 1982-12-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen "verwendung der kombination eines aromatase-hemmers mit einem antiandrogen zur prophylaxe und therapie der prostatahyperplasie"
DE3121153A1 (de) * 1981-05-22 1982-12-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen "verwendung von aromatase-hemmern zur prophylaxe und therapie der prostatahyperplasie"
US4634694A (en) * 1984-01-14 1987-01-06 Akzo N.V. Novel Δ4 - and Δ5 -androstene derivatives and pharmaceutical compositions containing these derivatives
US4745109A (en) * 1984-08-20 1988-05-17 Washington Research Foundation Suicide inhibitors of aromatase
GB8624251D0 (en) * 1986-10-09 1986-11-12 Erba Farmitalia "1,2-beta-methylene-4-substituted androstene-3,17 dione derivatives
DE3714965A1 (de) * 1987-04-30 1988-11-10 Schering Ag 3-methylen-4-androsten-17-one, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
DE3714964A1 (de) * 1987-04-30 1988-11-10 Schering Ag 15-alkyl-19-thio-4-androsten-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
EP0334425A1 (en) * 1988-03-24 1989-09-27 Akzo N.V. Novel delta4 - androstene derivatives
DE3820948A1 (de) * 1988-06-16 1989-12-21 Schering Ag 10ss, 11ss-ueberbrueckte steroide
DE4435368A1 (de) * 1994-09-22 1996-03-28 Schering Ag Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann
EP1854465A1 (en) 2006-05-12 2007-11-14 Alexander Tobias Teichmann Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers
US8969327B2 (en) 2010-04-08 2015-03-03 Emory University Substituted androst-4-ene diones
EP3666276A1 (en) 2018-12-14 2020-06-17 dcic Biopharmaceutical Limited Medication against estrogen-receptor beta (erbeta) positive breast tumor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4239681A (en) * 1974-04-15 1980-12-16 Richardson-Merrell Inc. Androst-4-en-19-ols
US4322416A (en) * 1980-06-27 1982-03-30 Merrell Dow Pharmaceuticals Inc. 10-Alkynyl steroids
US4289762A (en) * 1980-06-27 1981-09-15 Merrell Dow Pharmaceuticals Inc. 10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors

Also Published As

Publication number Publication date
ES524096A0 (es) 1984-10-01
FI832556L (fi) 1984-01-15
FI78710C (fi) 1989-09-11
EP0100566B1 (en) 1986-02-19
IE831495L (en) 1984-01-14
DK323083D0 (da) 1983-07-13
EP0100566A1 (en) 1984-02-15
HU188923B (en) 1986-05-28
FI832556A0 (fi) 1983-07-13
KR840005465A (ko) 1984-11-12
DK323083A (da) 1984-01-15
CA1199023A (en) 1986-01-07
AU555982B2 (en) 1986-10-16
JPS5931800A (ja) 1984-02-20
ZA834726B (en) 1984-10-31
DE3362176D1 (en) 1986-03-27
IE55077B1 (en) 1990-05-23
FI78710B (fi) 1989-05-31
AU1636583A (en) 1984-01-19

Similar Documents

Publication Publication Date Title
ES8500287A1 (es) Nuevos derivados de 19-tioandrostano
IL79211A0 (en) Diamino-androstane derivatives,process for their preparation and pharmaceutical compositions containing them
FI823917L (fi) Foerfarande foer framstaellning av nya pyridin-tiometyl-cefalosporin derivat
ES2005450A6 (es) Procedimiento para la preparacion de derivados n(4-etil-2,3-dioxo)-piperacin-1-iln-carbonilo.
ATE131061T1 (de) Förderung der osteogenese durch verwendung von vitamin d-derivaten.
FR2517309B1 (es)
ATE43589T1 (de) Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
FI941431A0 (fi) Menetelmä puolisynteettisten glykoaminoglykaanien valmistamiseksi, joilla on hepariini- tai heparaanirakenne modifioituna alfa-L-iduroni-2-0-sulfaattihapon 2-asemassa
NZ314991A (en) Preparation of cephem and isooxacephem derivatives using a thiophosphoric/carboxylic anhydride for acylation; 2-aminothiazolyl substituted diethoxy-phosphoryl ester intermediate
GB1412377A (en) Oxazolo- 5,4-d azepines
KR840006667A (ko) 세팔로스포린 유도체의 제조방법
ES8705417A1 (es) Un procedimiento para preparar derivados de 1,5-benzoxatiepina
SE8502317D0 (sv) Cefalosporinantibiotika
AU542419B2 (en) 17-amino-16-hydroxy steroids of the androstane and oestrane series
KR870002118A (ko) 벤질아민 유도체 및 그 제조방법
ES423178A1 (es) Procedimiento para la preparacion de esteres acilamidometi-licos de penicilinas y cefalosporinas.
KR900003178A (ko) 세펨 화합물의 제조방법
JPS56125385A (en) Novel piperidine derivative
JPS5278891A (en) Synthesis of cephalosporin antibiotics
BG38336A3 (en) Method for preparing 1- etoxycarbonyloxyethylic ester of 6- (d (-)- alpha- amino- alpha- phenylacetate- amino)- penicillanic acid
JPS5283778A (en) Hydrocarbylated cephem compound
KR940014365A (ko) 세팔로스포린 제조용 중간체의 제조방법
KR880011173A (ko) 세팔로스포린 유도체의 제조방법