ES8405394A1 - Un procedimiento para preparar derivados de imidazolina. - Google Patents
Un procedimiento para preparar derivados de imidazolina.Info
- Publication number
- ES8405394A1 ES8405394A1 ES521440A ES521440A ES8405394A1 ES 8405394 A1 ES8405394 A1 ES 8405394A1 ES 521440 A ES521440 A ES 521440A ES 521440 A ES521440 A ES 521440A ES 8405394 A1 ES8405394 A1 ES 8405394A1
- Authority
- ES
- Spain
- Prior art keywords
- imidazoline derivatives
- phenethyl
- hydroxyalkyl
- allyl
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Lock And Its Accessories (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Photoreceptors In Electrophotography (AREA)
- Paper (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE IMIDAZOLINA.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN EQUIVALENTE MOLAR DE ETILENDIAMINA Y UN ALCOHOL DE FORMULA ROH, PARA OBTENER DERIVADOS DE IMIDAZOLINA DE FORMULA (I), DONDE R ES ALCOHILO DE C 1 A 4, ALILO, BENCILO, FENETILO, O HIDROXIALCOHILO DE C 2 A 4; HX ES UN ACIDO TAL COMO CLORURO DE HIDROGENO; Y R ES ALCOHILO DE C 1 A 4. LA REACCION SE REALIZA A TEMPERATURA EN EL INTERVALO DE 0-25JC Y EN PRESENCIA DE UN DISOLVENTE TAL COMO ALCOHOL DE FORMULA ROH.TIENE APLICACION, POR PRESENTARACTIVIDAD ANTAGONISTA DEL ALFA2-ADRENORRECEPTOR, PARA EL TRATAMIENTO DE LA DEPRESION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8211205 | 1982-04-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES521440A0 ES521440A0 (es) | 1984-06-01 |
| ES8405394A1 true ES8405394A1 (es) | 1984-06-01 |
Family
ID=10529762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES521440A Expired ES8405394A1 (es) | 1982-04-17 | 1983-04-14 | Un procedimiento para preparar derivados de imidazolina. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4446148A (es) |
| EP (1) | EP0092328B1 (es) |
| JP (1) | JPS58192882A (es) |
| AT (1) | ATE27275T1 (es) |
| AU (1) | AU552397B2 (es) |
| CA (1) | CA1190932A (es) |
| CS (1) | CS233746B2 (es) |
| DD (1) | DD209628A5 (es) |
| DE (1) | DE3371631D1 (es) |
| DK (1) | DK160093C (es) |
| ES (1) | ES8405394A1 (es) |
| FI (1) | FI73676C (es) |
| GB (1) | GB2118548B (es) |
| GR (1) | GR78528B (es) |
| HU (1) | HU190894B (es) |
| IE (1) | IE54922B1 (es) |
| IL (1) | IL68318A (es) |
| NO (1) | NO158019C (es) |
| NZ (1) | NZ203680A (es) |
| PL (1) | PL143658B1 (es) |
| PT (1) | PT76558B (es) |
| SU (1) | SU1217257A3 (es) |
| ZA (1) | ZA832278B (es) |
| ZW (1) | ZW8783A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4882343A (en) * | 1987-08-28 | 1989-11-21 | G. D. Searle & Co. | Biarylalkylimidazole derivatives as anti-depressants |
| IL95760A0 (en) * | 1989-09-27 | 1992-05-25 | Rhone Poulenc Sante | Imidazole derivatives,their preparation and pharmaceutical compositions containing the same |
| FR2698789B1 (fr) * | 1992-12-07 | 1995-03-03 | Pf Medicament | Utilisation de l'idazoxan et ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson et de son évolution. |
| FR2700113B1 (fr) * | 1993-01-07 | 1995-03-24 | Pf Medicament | Utilisation de l'Idazoxan et ses dérivés pour la fabrication de médicaments destinés au traitement des maladies neurodégénératives et en particulier l'évolution de la maladie d'Alzheimer. |
| US6162455A (en) * | 1997-01-22 | 2000-12-19 | American Cyanamid Company | Method for increasing lean meat, improving the lean meat to fat ratio and improving amino acid utilization in warm-blooded animals |
| FR2766824B1 (fr) * | 1997-07-30 | 1999-09-10 | Adir | Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2795727B1 (fr) * | 1999-06-29 | 2001-09-21 | Pf Medicament | Nouveaux derives benzodioxanne imidazolines fluores, leur preparation et leurs applications en therapeutique |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2979511A (en) * | 1959-03-25 | 1961-04-11 | Olin Mathieson | Certain 1, 4-benzodioxanyl imidazolines and corresponding pyrimidines and process |
| PH16249A (en) * | 1980-02-04 | 1983-08-16 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives,its pharmaceutical composition and method of use |
| NZ199469A (en) * | 1981-01-30 | 1984-03-16 | Reckitt & Colmann Prod Ltd | Benzodioxanyl-2-imidazoline derivatives and pharmaceutical compositions |
-
1983
- 1983-03-24 NZ NZ203680A patent/NZ203680A/en unknown
- 1983-03-29 US US06/480,370 patent/US4446148A/en not_active Expired - Lifetime
- 1983-03-29 EP EP83301776A patent/EP0092328B1/en not_active Expired
- 1983-03-29 DE DE8383301776T patent/DE3371631D1/de not_active Expired
- 1983-03-29 CS CS832172A patent/CS233746B2/cs unknown
- 1983-03-29 AT AT83301776T patent/ATE27275T1/de active
- 1983-03-30 ZA ZA832278A patent/ZA832278B/xx unknown
- 1983-03-30 GB GB08308885A patent/GB2118548B/en not_active Expired
- 1983-03-31 CA CA000425114A patent/CA1190932A/en not_active Expired
- 1983-04-07 IL IL68318A patent/IL68318A/xx not_active IP Right Cessation
- 1983-04-11 AU AU13298/83A patent/AU552397B2/en not_active Ceased
- 1983-04-11 FI FI831199A patent/FI73676C/fi not_active IP Right Cessation
- 1983-04-12 SU SU833576788A patent/SU1217257A3/ru active
- 1983-04-13 ZW ZW87/83A patent/ZW8783A1/xx unknown
- 1983-04-14 GR GR71079A patent/GR78528B/el unknown
- 1983-04-14 NO NO831318A patent/NO158019C/no unknown
- 1983-04-14 ES ES521440A patent/ES8405394A1/es not_active Expired
- 1983-04-14 DK DK163783A patent/DK160093C/da not_active IP Right Cessation
- 1983-04-15 PT PT76558A patent/PT76558B/pt not_active IP Right Cessation
- 1983-04-15 HU HU831330A patent/HU190894B/hu not_active IP Right Cessation
- 1983-04-15 DD DD83249904A patent/DD209628A5/de not_active IP Right Cessation
- 1983-04-15 JP JP58066854A patent/JPS58192882A/ja active Granted
- 1983-04-15 PL PL1983241515A patent/PL143658B1/pl unknown
- 1983-04-15 IE IE858/83A patent/IE54922B1/en not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8307796A1 (es) | Un procedimiento para la preparacion de derivados de imidazolina. | |
| ES8401961A1 (es) | Procedimiento para la preparacion de nuevas n-(4-indolil-piperidino-alcohil-bencimidazolonas sustituidas. | |
| ES2001094A6 (es) | Un procedimiento para la preparacion de un derivado de guanina | |
| ES8405394A1 (es) | Un procedimiento para preparar derivados de imidazolina. | |
| EP0088385A3 (en) | 7-acylamino-3-cephem-4-carboxylic acid derivatives, processes for the preparation of the same and pharmaceutical composition comprising the same | |
| PT77231B (en) | Process for the preparation of 2-nitro-1,1-ethenediamines having a hypotensive effect and their use for the preparation of pharmaceutical compositions with a hypotensive effect | |
| IE820209L (en) | Imidazoline derivatives | |
| DK407885A (da) | 7-(2-(dialkylamino)ethyl)-4-hydroxy-1,3-benzimidazol-2-oner | |
| DE3266036D1 (en) | 3-piperidinylindole derivatives, their salts and preparation, their use in medicines and pharmaceutical preparations containing them | |
| PH20505A (en) | 1-acetonyl-2-(phenylimino)imidazolines and salts thereof and pharmaceutical compositions containing them | |
| AU567498B2 (en) | 5-phenyl-1h-2,3-dihydro-1,4-benzodiazepine derivatives. | |
| GB1480892A (en) | 3-nitropyrazole derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20011110 |