[go: up one dir, main page]

ES8402942A1 - Procedimiento para la produccion de un preparado de tromboplastina de tejidos. - Google Patents

Procedimiento para la produccion de un preparado de tromboplastina de tejidos.

Info

Publication number
ES8402942A1
ES8402942A1 ES518420A ES518420A ES8402942A1 ES 8402942 A1 ES8402942 A1 ES 8402942A1 ES 518420 A ES518420 A ES 518420A ES 518420 A ES518420 A ES 518420A ES 8402942 A1 ES8402942 A1 ES 8402942A1
Authority
ES
Spain
Prior art keywords
tissue
thromboplastine
preparing
composition
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518420A
Other languages
English (en)
Other versions
ES518420A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES8402942A1 publication Critical patent/ES8402942A1/es
Publication of ES518420A0 publication Critical patent/ES518420A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/839—Nerves; brain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Lubricants (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA TROMBOPLASTINA DE TEJIDO A PARTIR DE TEJIDOS DE ANIMALES MAMIFEROS, LA CUAL ES SENSIBLE FRENTE AL FACTOR DE COAGULACION VII.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, A PARTIR DE TEJIDO DE ANIMALES MAMIFEROS SE PREPARA POLVO SECADO CON ACETONA; SEGUNDA, EL POLVO OBTENIDO SE EXTRAE CON UNA SOLUCION DE SAL, QUE CONTIENE ENTRE UNO Y VEINTE MILIMOLES POR LITRO DE IONES CALCIO Y PREFERIBLEMENTE UN AGENTE TENSIOACTIVO; Y POR ULTIMO, SE SECA EL EXTRACTO OBTENIDO.DE APLICACION EN LA COAGULACION DE LA SANGREY EN EL CIERRE DE LAS HERIDAS VASCULARES.
ES518420A 1981-12-21 1982-12-21 Procedimiento para la produccion de un preparado de tromboplastina de tejidos. Granted ES518420A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813150596 DE3150596A1 (de) 1981-12-21 1981-12-21 Verfahren zur herstellung von gewebsthromboplastin

Publications (2)

Publication Number Publication Date
ES8402942A1 true ES8402942A1 (es) 1984-03-01
ES518420A0 ES518420A0 (es) 1984-03-01

Family

ID=6149306

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518420A Granted ES518420A0 (es) 1981-12-21 1982-12-21 Procedimiento para la produccion de un preparado de tromboplastina de tejidos.

Country Status (11)

Country Link
US (1) US4416812A (es)
EP (1) EP0083773B1 (es)
JP (1) JPS58154515A (es)
AT (1) ATE13447T1 (es)
CA (1) CA1195614A (es)
DD (1) DD208811A5 (es)
DE (2) DE3150596A1 (es)
DK (1) DK158474C (es)
ES (1) ES518420A0 (es)
NO (1) NO160747C (es)
ZA (1) ZA829315B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4928603A (en) * 1984-09-07 1990-05-29 The Trustees Of Columbia University In The City Of New York Method of preparing a cryoprecipitated suspension and use thereof
US4755461A (en) * 1986-04-17 1988-07-05 Bio/Data Corporation Tableted blood plasma microconcentrated thromboplastin coagulation reagent
US5589173A (en) * 1986-11-04 1996-12-31 Genentech, Inc. Method and therapeutic compositions for the treatment of myocardial infarction
ATE120645T1 (de) * 1986-11-04 1995-04-15 Genentech Inc Verfahren und therapeutische zubereitungen für die behandlung von gerinnungsstörungen.
US5017556A (en) * 1986-11-04 1991-05-21 Genentech, Inc. Treatment of bleeding disorders using lipid-free tissue factor protein
US5270451A (en) * 1988-11-23 1993-12-14 Baxter Diagnostics Inc. Extraction method for preparing thromboplastin reagents
US5281528A (en) * 1989-12-18 1994-01-25 Warner-Lambert Company Process for purified thromboplastin for ultra-pure thrombin preparation
US5254350A (en) * 1991-07-22 1993-10-19 Helena Laboratories Corporation Method of preparing a thromboplastin extract
JP3180824B2 (ja) * 1991-08-30 2001-06-25 シスメックス株式会社 血液凝固試薬
CA2080428C (en) * 1991-10-22 2004-01-27 Ray F. Ebert A method for preparing a thromboplastin reagent from cultured cells that is suitable for use in the prothrombin time test
US5358853A (en) * 1992-08-03 1994-10-25 Akzo Av Liquid thromboplastin reagent
US5418141A (en) * 1994-05-06 1995-05-23 Avocet Medical, Inc. Test articles for performing dry reagent prothrombin time assays
DE19538716A1 (de) * 1995-10-18 1997-04-24 Behringwerke Ag Verfahren zur Quantifizierung von aktiviertem Gerinnungsfaktor VII (FVIIa)
DE19538715A1 (de) 1995-10-18 1997-04-30 Behringwerke Ag Verfahren zur Reinigung von Faktor VII und aktiviertem Faktor VII
NL1008674C2 (nl) * 1998-03-23 1999-09-24 Harimex Bv Werkwijze voor het bereiden van tromboplastine uit dierlijk weefsel.
AU1311800A (en) 1998-10-07 2000-04-26 Sigma-Aldrich Co. Thromboplastin reagents and methods for preparing and using such reagents
US6183979B1 (en) * 1999-03-24 2001-02-06 International Technidyne Corporation Preparation of dried synthetic prothrombin time reagents
JP4526152B2 (ja) * 2000-03-08 2010-08-18 シスメックス株式会社 プロトロンビン時間測定試薬
GB0327094D0 (en) * 2003-11-21 2003-12-24 Inverness Medical Switzerland Laminated device
US7148067B2 (en) * 2004-08-31 2006-12-12 The Board Of Trustees Of The University Of Illinois Thromboplastin reagents
US20080260858A1 (en) * 2005-02-16 2008-10-23 The Board Of Trustees Of The University Of Illnois Universal Procoagulant
CA2600907C (en) * 2005-03-04 2016-06-28 The Board Of Trustees Of The University Of Illinois Coagulation and fibrinolytic cascades modulator
US8821861B2 (en) * 2007-10-05 2014-09-02 The Board Of Trustees Of The University Of Illinois Fibrin sealant
US20100297257A1 (en) 2007-11-09 2010-11-25 National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs) Anticoagulant antagonist and hemophillia procoagulant
DE102007062323A1 (de) * 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Langzeitstabiles Thromboplastin-Reagenz
EP2405274A1 (en) 2010-07-06 2012-01-11 Good biomarker Sciences B.V. Monitoring anticoagulant therapy and identifying reversible direct factor Xa inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2847350A (en) * 1954-05-27 1958-08-12 Ortho Pharma Corp Preparation of highly active thromboplastin
US2847348A (en) * 1954-05-27 1958-08-12 Ortho Pharma Corp Plasma fractionation and product therefrom
US2842480A (en) * 1954-05-27 1958-07-08 Ortho Pharma Corp Preparation of thromboplastin
US2921000A (en) * 1956-05-22 1960-01-12 Ortho Pharma Corp Thromboplastin
NL238873A (es) * 1958-05-16
US3228841A (en) * 1965-06-10 1966-01-11 Warner Lambert Pharmaceutical Diagnostic reagent composition for determining blood coagulation factors and method of use
US3522148A (en) * 1965-08-13 1970-07-28 Dade Reagents Inc Stabilized thromboplastin preparation
US3980432A (en) * 1973-04-02 1976-09-14 Behringwerke Aktiengesellschaft Partial thromboplastin, its use as diagnostic agent and process for preparing it
ES431736A1 (es) * 1973-11-13 1977-05-16 Behringwerke Ag Procedimiento para la preparacion de un agente para diagnos-tico para el proposito de efectuar el control de la capaci- dad de coagulacion de la sangre.

Also Published As

Publication number Publication date
JPS58154515A (ja) 1983-09-14
ZA829315B (en) 1983-10-26
DE3263793D1 (en) 1985-06-27
US4416812A (en) 1983-11-22
CA1195614A (en) 1985-10-22
NO824279L (no) 1983-06-22
NO160747B (no) 1989-02-13
DD208811A5 (de) 1984-04-11
NO160747C (no) 1989-05-24
DK540082A (da) 1983-06-22
ATE13447T1 (de) 1985-06-15
EP0083773B1 (de) 1985-05-22
DK158474C (da) 1990-10-15
ES518420A0 (es) 1984-03-01
DK158474B (da) 1990-05-21
DE3150596A1 (de) 1983-06-30
JPH0339267B2 (es) 1991-06-13
EP0083773A1 (de) 1983-07-20

Similar Documents

Publication Publication Date Title
ES8402942A1 (es) Procedimiento para la produccion de un preparado de tromboplastina de tejidos.
ES471896A1 (es) Procedimiento para preparar particulas conteniendo enzimas
MY8500594A (en) Acaricidal, larvicidaland ovicidal tetrazine derivatives and compositions, processes for their preparation and methods of using them
ATA387777A (de) Verfahren zur kontinuierlichen herstellung von thermoplastischen polyurethanen
JPS54107941A (en) Preparation of impregnating polymer latex composition
JPS57136596A (en) Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same
AU549794B2 (en) Manufacture of soap powder
JPS5547214A (en) Preparation of minute zinc phosphate
GB2028314B (en) Process for the preparation of dicyclopentylene (2,2-bis(4-alkyl-6-t-butylphenols
JPS545097A (en) Preparation of immobilized glucose isomerase
DE2961465D1 (en) Process for the preparation of 3,3-dimethyl-2-oxo-butanoic acid
DE2962886D1 (en) Derivatives of l-cysteine, their use as medicaments and process for their preparation
DE2961653D1 (en) Alkylaminopropanol derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazoles, processes for their preparation and therapeutical compositions containing them
GB1471854A (en) Process for preparing cyclohexanone
JPS54132600A (en) Preparation of pectic acid alkali metal salt
JPS5517347A (en) Production of poultice with high water content
JPS54129120A (en) Use of plant meristem acting substance against impregnating material
JPS5223038A (en) Process for preparation of styrenesulfonic acid alkali metal salts
JPS5581855A (en) Adduct of pantethine with metal salt
DE2964521D1 (en) Process for the manufacture of the pure sodium hydroxide addition compounds of cis-naphthoylene-bis-benzimidazoles
DE2860035D1 (en) Process for the preparation of sulfonic acid groups and phosphonate groups bearing polyisocyanate mixtures
JPS54138086A (en) Preparation of coagulation alginate
GR60038B (en) Preparation process of calcium salt of 2,5-dihydroxybenzenesulphonic acid
GB2013196A (en) Process for the Electrochemical Preparation of 2-Amino-2-Ethyl- Thiophene
JPS5212622A (en) Process and equipment for producing zincdust