ES8304060A1 - "procedimiento para la preparacion de 3,4,5-trimetoxibenzoato de 2-(4-isobutilfenil)propanol-1". - Google Patents
"procedimiento para la preparacion de 3,4,5-trimetoxibenzoato de 2-(4-isobutilfenil)propanol-1".Info
- Publication number
- ES8304060A1 ES8304060A1 ES513331A ES513331A ES8304060A1 ES 8304060 A1 ES8304060 A1 ES 8304060A1 ES 513331 A ES513331 A ES 513331A ES 513331 A ES513331 A ES 513331A ES 8304060 A1 ES8304060 A1 ES 8304060A1
- Authority
- ES
- Spain
- Prior art keywords
- antiinflammatory
- analgesic
- preparation
- pharmaceutical compositions
- new compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000001754 anti-pyretic effect Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000008569 process Effects 0.000 title 1
- IZXWIWYERZDWOA-UHFFFAOYSA-N 2-[4-(2-methylpropyl)phenyl]propan-1-ol Chemical compound CC(C)CC1=CC=C(C(C)CO)C=C1 IZXWIWYERZDWOA-UHFFFAOYSA-N 0.000 abstract 1
- BUHYMJLFRZAFBF-UHFFFAOYSA-N 3,4,5-trimethoxybenzoyl chloride Chemical compound COC1=CC(C(Cl)=O)=CC(OC)=C1OC BUHYMJLFRZAFBF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- -1 compound 2-(4-isobutylphenyl)1-propanol 3,4,5-trimethoxybenzoate Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 3,4,5-TRIMETOXIBENZOATO DE 2-(4-ISOBUTILFENIL)-PROPANOL-1, QUE TIENE APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANALGESICA, ANTIINFLAMATORIA Y ANTIPIRETICA. CONSISTE EN LA REACCION DEL CLORURO DEL ACIDO 3,4,5-TRIMETOXIBENZOICO CON 2-(4-ISOBUTILFENIL)PROPANOL-1. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE APROTICO, EN PRESENCIA DE ACEPTORES DE ACIDO, TALES COMO PIRIDINA O TRIETILAMINA, A UNA TEMPERATURA COMPRENDIDA ENTRE 20 C Y 100 C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20074/82A IT1190728B (it) | 1982-03-10 | 1982-03-10 | Composto ad attivita' analgesica,antiinfiammatoria e antipiretica,procedimento per la sua preparazione e relative composizioni farmaceutiche |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8304060A1 true ES8304060A1 (es) | 1983-03-01 |
| ES513331A0 ES513331A0 (es) | 1983-03-01 |
Family
ID=11163593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES513331A Granted ES513331A0 (es) | 1982-03-10 | 1982-06-22 | "procedimiento para la preparacion de 3,4,5-trimetoxibenzoato de 2-(4-isobutilfenil)propanol-1". |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4435591A (es) |
| EP (1) | EP0088147A1 (es) |
| JP (1) | JPS5931735A (es) |
| AU (1) | AU8505482A (es) |
| CA (1) | CA1173056A (es) |
| ES (1) | ES513331A0 (es) |
| GR (1) | GR76157B (es) |
| IT (1) | IT1190728B (es) |
| PT (1) | PT75106A (es) |
| ZA (1) | ZA824414B (es) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1445969A1 (de) | 1963-07-24 | 1969-11-20 | Krewel Werke Gmbh | Verfahren zur Herstellung von basischen 3,4,5-Trimethoxybenzoesaeureestern |
| IT1121509B (it) * | 1979-05-25 | 1986-04-02 | Ripari Gero Istituto Farmacao | Esteri del 2-(4-isobutilfenil)propanolo-1,processo per la loro preparazione e composizioni farmaceutiche che li contengono |
-
1982
- 1982-03-10 IT IT20074/82A patent/IT1190728B/it active
- 1982-06-16 EP EP82105269A patent/EP0088147A1/en not_active Withdrawn
- 1982-06-21 AU AU85054/82A patent/AU8505482A/en not_active Abandoned
- 1982-06-22 ES ES513331A patent/ES513331A0/es active Granted
- 1982-06-22 ZA ZA824414A patent/ZA824414B/xx unknown
- 1982-06-22 CA CA000405747A patent/CA1173056A/en not_active Expired
- 1982-06-22 US US06/390,979 patent/US4435591A/en not_active Expired - Fee Related
- 1982-06-23 PT PT75106A patent/PT75106A/pt unknown
- 1982-06-23 GR GR68537A patent/GR76157B/el unknown
- 1982-06-25 JP JP57110560A patent/JPS5931735A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IT8220074A0 (it) | 1982-03-10 |
| AU8505482A (en) | 1983-09-15 |
| IT1190728B (it) | 1988-02-24 |
| CA1173056A (en) | 1984-08-21 |
| JPS5931735A (ja) | 1984-02-20 |
| EP0088147A1 (en) | 1983-09-14 |
| GR76157B (es) | 1984-08-03 |
| ES513331A0 (es) | 1983-03-01 |
| PT75106A (en) | 1982-07-01 |
| US4435591A (en) | 1984-03-06 |
| ZA824414B (en) | 1983-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19851214 |