ES8206501A1 - Procedimiento para la preparacion de derivados de 2-guanidi-notiazol - Google Patents
Procedimiento para la preparacion de derivados de 2-guanidi-notiazolInfo
- Publication number
- ES8206501A1 ES8206501A1 ES501736A ES501736A ES8206501A1 ES 8206501 A1 ES8206501 A1 ES 8206501A1 ES 501736 A ES501736 A ES 501736A ES 501736 A ES501736 A ES 501736A ES 8206501 A1 ES8206501 A1 ES 8206501A1
- Authority
- ES
- Spain
- Prior art keywords
- optionally substituted
- alkyl
- cyano
- alkoxy
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008327 2-guanidinothiazoles Chemical class 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000006828 (C2-C7) alkoxycarbonyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- -1 hydroxy, cyano, amino Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 229940122957 Histamine H2 receptor antagonist Drugs 0.000 abstract 1
- 241000534944 Thia Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 230000002467 anti-pepsin effect Effects 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 125000001231 benzoyloxy group Chemical group C(C1=CC=CC=C1)(=O)O* 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000003485 histamine H2 receptor antagonist Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14494680A | 1980-04-29 | 1980-04-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES501736A0 ES501736A0 (es) | 1982-08-16 |
| ES8206501A1 true ES8206501A1 (es) | 1982-08-16 |
Family
ID=22510873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES501736A Expired ES8206501A1 (es) | 1980-04-29 | 1981-04-28 | Procedimiento para la preparacion de derivados de 2-guanidi-notiazol |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS574977A (de) |
| AR (1) | AR231538A1 (de) |
| AU (1) | AU540239B2 (de) |
| BE (1) | BE888602A (de) |
| CH (1) | CH646964A5 (de) |
| DE (1) | DE3116890A1 (de) |
| DK (1) | DK188881A (de) |
| ES (1) | ES8206501A1 (de) |
| FR (1) | FR2481280A1 (de) |
| GB (1) | GB2076397B (de) |
| IE (1) | IE51151B1 (de) |
| IL (1) | IL62747A (de) |
| IT (1) | IT1146750B (de) |
| NL (1) | NL8102099A (de) |
| NZ (1) | NZ196923A (de) |
| SE (1) | SE452462B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4501747A (en) * | 1982-05-10 | 1985-02-26 | Sanofi | Certain amide derivatives of 2-guanidino-thiazoles and compositions containing same |
| FR2531705B1 (fr) * | 1982-08-13 | 1986-12-05 | Sanofi Sa | Amidobenzamides, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant |
| JPS59104370A (ja) * | 1982-12-03 | 1984-06-16 | Kotobuki Seiyaku Kk | チアゾ−ル誘導体及びその製造方法 |
| GB2138803B (en) * | 1983-04-26 | 1986-06-18 | Shionogi & Co | 2-guanidino-4-hydroxymethylthiazole and derivatives thereof |
| US4680300A (en) * | 1985-01-10 | 1987-07-14 | Syntex (U.S.A.) Inc. | Anti-inflammatory guanidines |
| US4837316A (en) * | 1985-08-29 | 1989-06-06 | Fujirebio Kabushiki Kaisha | Alkylamide derivatives with H2 -receptor antagonistic and cytoprotective action |
| EP0385525B1 (de) * | 1989-03-03 | 1994-04-13 | Akzo Nv | Aminoethylthiazole und Aminoethyloxazol-Derivate. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4165378A (en) * | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
| IE47044B1 (en) * | 1977-04-20 | 1983-12-14 | Ici Ltd | Guanidine derivatives |
| US4315009A (en) * | 1978-01-18 | 1982-02-09 | Imperial Chemical Industries Limited | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
| US4309435A (en) * | 1978-10-16 | 1982-01-05 | Imperial Chemical Industries Ltd. | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
| DE2966646D1 (en) | 1978-10-16 | 1984-03-15 | Ici Plc | Antisecretory branched-chain heterocyclic guanidine derivatives, processes for their manufacture, intermediates, and pharmaceutical compositions containing said derivatives |
| EP0014057B1 (de) * | 1979-01-18 | 1985-01-02 | Imperial Chemical Industries Plc | Guanidin-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
| PH16099A (en) * | 1979-03-06 | 1983-06-24 | Yamanouchi Pharma Co Ltd | Guanidinothiazole compounds,process for preparing them and medical composition containing them |
| GR71929B (de) * | 1979-11-13 | 1983-08-19 | Ici Ltd | |
| JPS5754177A (ja) * | 1980-09-19 | 1982-03-31 | Teikoku Hormone Mfg Co Ltd | Chikanchiazoorujudotai |
| JPS57102852A (en) * | 1980-12-19 | 1982-06-26 | Shionogi & Co Ltd | Dicarboxylic acid diamide |
-
1981
- 1981-04-24 NZ NZ196923A patent/NZ196923A/xx unknown
- 1981-04-28 JP JP6473981A patent/JPS574977A/ja active Granted
- 1981-04-28 DK DK188881A patent/DK188881A/da not_active Application Discontinuation
- 1981-04-28 DE DE19813116890 patent/DE3116890A1/de not_active Ceased
- 1981-04-28 SE SE8102683A patent/SE452462B/sv not_active IP Right Cessation
- 1981-04-28 FR FR8108468A patent/FR2481280A1/fr active Granted
- 1981-04-28 BE BE0/204631A patent/BE888602A/fr not_active IP Right Cessation
- 1981-04-28 ES ES501736A patent/ES8206501A1/es not_active Expired
- 1981-04-28 NL NL8102099A patent/NL8102099A/nl not_active Application Discontinuation
- 1981-04-29 IT IT67585/81A patent/IT1146750B/it active
- 1981-04-29 CH CH279381A patent/CH646964A5/de not_active IP Right Cessation
- 1981-04-29 GB GB8113289A patent/GB2076397B/en not_active Expired
- 1981-04-29 IL IL62747A patent/IL62747A/xx unknown
- 1981-04-29 IE IE956/81A patent/IE51151B1/en unknown
- 1981-04-29 AU AU69966/81A patent/AU540239B2/en not_active Ceased
-
1984
- 1984-01-01 AR AR23153884D patent/AR231538A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| NZ196923A (en) | 1983-12-16 |
| ES501736A0 (es) | 1982-08-16 |
| SE452462B (sv) | 1987-11-30 |
| DK188881A (da) | 1981-10-30 |
| GB2076397A (en) | 1981-12-02 |
| BE888602A (fr) | 1981-10-28 |
| SE8102683L (sv) | 1981-10-30 |
| IE51151B1 (en) | 1986-10-15 |
| JPH027952B2 (de) | 1990-02-21 |
| AU540239B2 (en) | 1984-11-08 |
| IE810956L (en) | 1981-10-29 |
| CH646964A5 (de) | 1984-12-28 |
| IL62747A (en) | 1984-10-31 |
| AU6996681A (en) | 1981-11-05 |
| IL62747A0 (en) | 1981-06-29 |
| IT8167585A0 (it) | 1981-04-29 |
| NL8102099A (nl) | 1981-11-16 |
| FR2481280A1 (fr) | 1981-10-30 |
| IT1146750B (it) | 1986-11-19 |
| FR2481280B1 (de) | 1983-10-28 |
| GB2076397B (en) | 1984-02-08 |
| DE3116890A1 (de) | 1982-03-04 |
| JPS574977A (en) | 1982-01-11 |
| AR231538A1 (es) | 1984-12-28 |
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