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Fisons Ltd
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Fisons Ltd
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Publication date
Priority claimed from EP81302546Aexternal-prioritypatent/EP0043194A3/en
Application filed by Fisons LtdfiledCriticalFisons Ltd
Publication of ES503139A0publicationCriticalpatent/ES503139A0/en
Publication of ES8203826A1publicationCriticalpatent/ES8203826A1/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDURE FOR THE OBTAINING OF BICYCLE COMPOUNDS AND THEIR PHYSIOLOGICALLY COMPATIBLE SALTS, OF FORMULA (I), IN WHICH ONE OF A, B AND D IS HYDROGEN AND THE OTHER TWO CAN BE VARIOUS TYPES OF RADICALS, THE SAME AS R2 AND R3. IT CONSISTS OF THE REDUCTION OR HYDROLYSIS REACTION OF A COMPOUND OF FORMULA (II), IN WHICH ONE OF A1, B1 AND D1 IS HYDROGEN AND THE OTHER TWO ARE EQUAL TO B AND D, RESPECTIVELY, OR ARE BLOCKING GROUPS; Q IS -CH2NR2R3, -CN OR -CONR2R3, BEING R2 AND R3 THE SAME AS IN FORMULA (I). THE REDUCTION CAN BE CARRIED OUT WITH A METALLIC HYDRIDE OR WITH CATALYTIC HYDROGEN, AND THE HYDROLYSIS IS CARRIED OUT IN A MEDIUM ACID. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND PARKINSON'S DISEASE. (Machine-translation by Google Translate, not legally binding)
ES503139A1980-06-191981-06-17A procedure for obtaining biciclic compounds (Machine-translation by Google Translate, not legally binding)
ExpiredES8203826A1
(en)
(Arylmethyl)aryl-amino-cyclohexanols, -cyclohexanes, -cyclohexenes and intermediates thereof, a process for preparing the same and their use as medicaments.