ES8106505A1 - Procedimiento para la obtencion de un derivado amidico de latrimetoprima - Google Patents
Procedimiento para la obtencion de un derivado amidico de latrimetoprimaInfo
- Publication number
- ES8106505A1 ES8106505A1 ES494151A ES494151A ES8106505A1 ES 8106505 A1 ES8106505 A1 ES 8106505A1 ES 494151 A ES494151 A ES 494151A ES 494151 A ES494151 A ES 494151A ES 8106505 A1 ES8106505 A1 ES 8106505A1
- Authority
- ES
- Spain
- Prior art keywords
- trimetoprima
- translation
- procedure
- obtaining
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 title abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 abstract 1
- -1 fthalide anhydride Chemical class 0.000 abstract 1
- 239000012454 non-polar solvent Substances 0.000 abstract 1
- 239000003507 refrigerant Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- 239000008096 xylene Substances 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE LA MONOAMIDA DE 2,4-DIAMINO-5-(3'',4'',5''-TRIMETOXIBENZIL)-PIRIMIDINA(TRIMETOPRIMA). CONSISTE EN HACER REACCIONAR LA TRIMETOPIRIMA CON EL ANHIDRIDO FTALICO EN MEDIO DE UN SOLVENTE NO POLAR TAL COMO EL BENCENO, TOLUENO O XILENO. EL PRODUCTO OBTENIDO SE PURIFICA POR LAVADOS CON HIDROXIDO SODICO A PH 9 Y POSTERIOR ACIDULACION A PH 5. SE EMPLEA UN REACTOR DOTADO CON AGITADOR MECANICO Y REFRIGENRANTE A REFLUJO.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES494151A ES494151A0 (es) | 1980-08-09 | 1980-08-09 | Procedimiento para la obtencion de un derivado amidico de latrimetoprima |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES494151A ES494151A0 (es) | 1980-08-09 | 1980-08-09 | Procedimiento para la obtencion de un derivado amidico de latrimetoprima |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8106505A1 true ES8106505A1 (es) | 1981-08-01 |
| ES494151A0 ES494151A0 (es) | 1981-08-01 |
Family
ID=8480947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES494151A Granted ES494151A0 (es) | 1980-08-09 | 1980-08-09 | Procedimiento para la obtencion de un derivado amidico de latrimetoprima |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES494151A0 (es) |
-
1980
- 1980-08-09 ES ES494151A patent/ES494151A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES494151A0 (es) | 1981-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20010301 |