ES540858A0 - Un procedimiento para la preparacion de derivados de espiro-hidantoina - Google Patents

Un procedimiento para la preparacion de derivados de espiro-hidantoina

Info

Publication number: ES540858A0
Authority: ES; Spain
Prior art keywords: spiro; trione; imidazolidine; indoline; spiral
Prior art date: 1983-05-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES540858A

Other languages

English (en)

Other versions

ES8607304A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Corp Belgium

Pfizer Corp SRL

Original Assignee

Pfizer Corp Belgium

Pfizer Corp SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-05-25

Filing date

1985-03-01

Publication date

1986-06-01

1985-03-01 Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium

1986-06-01 Publication of ES8607304A1 publication Critical patent/ES8607304A1/es

1986-06-01 Publication of ES540858A0 publication Critical patent/ES540858A0/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cosmetics (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
External Artificial Organs (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Fats And Perfumes (AREA)

ES540858A 1983-05-25 1985-03-01 Un procedimiento para la preparacion de derivados de espiro-hidantoina Expired ES8607304A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/497,962 US4464380A (en)	1983-05-25	1983-05-25	Imidazolidinedione derivatives

Publications (2)

Publication Number	Publication Date
ES8607304A1 ES8607304A1 (es)	1986-06-01
ES540858A0 true ES540858A0 (es)	1986-06-01

Family

ID=23979057

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES532736A Expired ES8600764A1 (es)	1983-05-25	1984-05-23	Un procedimiento para la preparacion de derivados de espiro-hidantoina
ES540858A Expired ES8607304A1 (es)	1983-05-25	1985-03-01	Un procedimiento para la preparacion de derivados de espiro-hidantoina

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ES532736A Expired ES8600764A1 (es)	1983-05-25	1984-05-23	Un procedimiento para la preparacion de derivados de espiro-hidantoina

Country Status (19)

Country	Link
US (1)	US4464380A (es)
EP (1)	EP0127412B1 (es)
JP (1)	JPS604183A (es)
KR (1)	KR860001869B1 (es)
AT (1)	ATE57531T1 (es)
AU (1)	AU543916B2 (es)
CA (1)	CA1266270A (es)
DE (1)	DE3483402D1 (es)
DK (1)	DK163924C (es)
ES (2)	ES8600764A1 (es)
FI (1)	FI78699C (es)
GR (1)	GR82020B (es)
HU (1)	HU190548B (es)
IE (1)	IE57520B1 (es)
IL (1)	IL71904A (es)
PH (1)	PH21151A (es)
PL (3)	PL252850A1 (es)
PT (1)	PT78625A (es)
YU (2)	YU43931B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0172719B1 (en) *	1984-08-20	1988-09-21	Pfizer Inc.	Process for the production as asymmetric hydantoins
US4762839A (en) *	1985-06-06	1988-08-09	Tanabe Seiyaku Co., Ltd.	Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications
JPS63132889A (ja) *	1986-11-21	1988-06-04	Tanabe Seiyaku Co Ltd	キナゾリノン誘導体
US4841079A (en) *	1987-08-07	1989-06-20	Pfizer, Inc.	Process for the production of asymmetric hydantoins
ATE229948T1 (de) *	1995-10-18	2003-01-15	Hoffmann La Roche	Hydroxymethylierung von tocopherolen
NZ512870A (en)	1998-12-19	2003-11-28	Janssen Pharmaceutica Nv	Antihistaminic spiro compounds
EP2013216A2 (en) *	2006-02-07	2009-01-14	AstraZeneca AB	Novel spiro [imidazolidine-4, 3' -indole] 2, 2', 5' (1h) triones for treatment of conditions associated with vanilloid receptor 1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3821383A (en) *	1972-07-10	1974-06-28	Ayerst Mckenna & Harrison	Compositions for and a method of treating diabetic complications
US4200642A (en) *	1978-08-21	1980-04-29	Pfizer Inc.	Spiro-oxazolidindiones
IE50332B1 (en) *	1979-11-13	1986-04-02	Ici Ltd	1'-substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones,processes for their manufacture and pharmaceutical compositions thereof
ZA806623B (en) *	1979-11-13	1981-12-30	Ici Ltd	Substituted indoline-2-one derivatives
US4248882A (en) *	1980-02-12	1981-02-03	Pfizer Inc.	Treating diabetes-associated complications with hydantoin amines
IE52879B1 (en) *	1981-05-12	1988-03-30	Ici Plc	Pharmaceutical spiro-hydantoin derivatives

1983
- 1983-05-25 US US06/497,962 patent/US4464380A/en not_active Expired - Fee Related
1984
- 1984-05-21 DE DE8484303420T patent/DE3483402D1/de not_active Expired - Lifetime
- 1984-05-21 PT PT78625A patent/PT78625A/pt not_active IP Right Cessation
- 1984-05-21 EP EP84303420A patent/EP0127412B1/en not_active Expired - Lifetime
- 1984-05-21 AT AT84303420T patent/ATE57531T1/de not_active IP Right Cessation
- 1984-05-22 DK DK250084A patent/DK163924C/da not_active IP Right Cessation
- 1984-05-23 CA CA000454883A patent/CA1266270A/en not_active Expired - Lifetime
- 1984-05-23 PL PL25285084A patent/PL252850A1/xx unknown
- 1984-05-23 IL IL71904A patent/IL71904A/xx unknown
- 1984-05-23 ES ES532736A patent/ES8600764A1/es not_active Expired
- 1984-05-23 PL PL1984242850A patent/PL143070B1/pl unknown
- 1984-05-23 PH PH30711A patent/PH21151A/en unknown
- 1984-05-23 YU YU897/84A patent/YU43931B/xx unknown
- 1984-05-23 PL PL1984247804A patent/PL143290B1/pl unknown
- 1984-05-24 FI FI842079A patent/FI78699C/fi not_active IP Right Cessation
- 1984-05-24 IE IE1294/84A patent/IE57520B1/en not_active IP Right Cessation
- 1984-05-24 HU HU842021A patent/HU190548B/hu not_active IP Right Cessation
- 1984-05-24 GR GR74816A patent/GR82020B/el unknown
- 1984-05-24 AU AU28563/84A patent/AU543916B2/en not_active Ceased
- 1984-05-24 KR KR1019840002843A patent/KR860001869B1/ko not_active IP Right Cessation
- 1984-05-25 JP JP59106330A patent/JPS604183A/ja active Granted
1985
- 1985-03-01 ES ES540858A patent/ES8607304A1/es not_active Expired
1986
- 1986-12-11 YU YU2122/86A patent/YU43958B/xx unknown

Also Published As

Publication number	Publication date
FI78699B (fi)	1989-05-31
HUT34194A (en)	1985-02-28
EP0127412A2 (en)	1984-12-05
PT78625A (en)	1984-06-01
DK250084D0 (da)	1984-05-22
ES8607304A1 (es)	1986-06-01
FI78699C (fi)	1989-09-11
ATE57531T1 (de)	1990-11-15
EP0127412A3 (en)	1987-09-02
KR840009101A (ko)	1984-12-24
IL71904A0 (en)	1984-09-30
ES532736A0 (es)	1985-10-16
YU89784A (en)	1987-04-30
YU43931B (en)	1989-12-31
DK163924C (da)	1992-09-14
KR860001869B1 (ko)	1986-10-24
YU212286A (en)	1987-10-31
US4464380A (en)	1984-08-07
PL143290B1 (en)	1988-02-29
FI842079A0 (fi)	1984-05-24
PH21151A (en)	1987-07-30
JPS604183A (ja)	1985-01-10
DE3483402D1 (de)	1990-11-22
GR82020B (es)	1984-12-12
YU43958B (en)	1989-12-31
FI842079A (fi)	1984-11-26
IE57520B1 (en)	1993-05-19
DK163924B (da)	1992-04-21
CA1266270A (en)	1990-02-27
AU2856384A (en)	1984-11-29
PL252850A1 (en)	1985-11-19
IE841294L (en)	1984-11-25
AU543916B2 (en)	1985-05-09
HU190548B (en)	1986-09-29
JPH0573754B2 (es)	1993-10-15
DK250084A (da)	1984-11-26
PL247804A1 (en)	1985-08-13
EP0127412B1 (en)	1990-10-17
IL71904A (en)	1988-01-31
ES8600764A1 (es)	1985-10-16
PL143070B1 (en)	1988-01-30

Publication	Publication Date	Title
MY102038A (en)	1992-02-29	4-substituted androstendione derivatives and process for their preparation
IE790088L (en)	1979-07-18	Thienohydantoin derivatives
ES540858A0 (es)	1986-06-01	Un procedimiento para la preparacion de derivados de espiro-hidantoina
AU7767287A (en)	1988-03-17	New imidazolylguanidine derivatives, processes for their preparation and medicaments containing these compounds
NO893909L (no)	1990-04-04	Fremgangsmaate for fremstilling av terapeutisk aktive imidazol-derivater.
IE851155L (en)	1985-11-10	Benzo-(pyrano and thiopyrano)-pyridines
BG60101B2 (bg)	1993-10-29	Метод за получаване на 4-флуор-2-(((4-метокси-2- пиридинил)метил)тионил)-1н-бензимидазол
MY103765A (en)	1993-09-30	Azolidinedione derivatives
MY101896A (en)	1992-02-15	New tetracyclic indole derivatives
IE800672L (en)	1980-10-04	Spiro-quinolone hydantoins
ES8407050A1 (es)	1984-08-16	Un derivado de trifluormetil-espiro(imidazolidina-4,3'-indolina)-2,2'5-triona.
FI832959A0 (fi)	1983-08-18	Spiro/2h-1,4-benzodiazepin-3(5h)4'-piperidin och 3'-pyrrolidin/foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel
DK423186A (da)	1987-03-06	Spiro-(benzofuran-2(3h),1`cycloheptan)-derivater, deres fremstilling og anvendelse samt mellemprodukt til fremstillingen
NO882279D0 (no)	1988-05-25	Fremgangsmaate for fremstilling av terapeutisk aktive endo-bicyklo (2,2,1) heptyl-adenosin-derivater.

Legal Events

Date	Code	Title	Description
1997-07-16	FD1A	Patent lapsed	Effective date: 19970519