ES532044A0 - Un procedimiento de preparacion de derivados de bencimidazol. - Google Patents

Un procedimiento de preparacion de derivados de bencimidazol.

Info

Publication number: ES532044A0
Authority: ES; Spain
Prior art keywords: carbon atoms; group; preparation; oc2h5; och3
Prior art date: 1981-08-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES532044A

Other languages

English (en)

Other versions

ES8502109A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hassle AB

Original Assignee

Hassle AB

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-08-13

Filing date

1984-04-30

Publication date

1984-12-16

1984-04-30 Application filed by Hassle AB filed Critical Hassle AB

1984-12-16 Publication of ES532044A0 publication Critical patent/ES532044A0/es

1984-12-16 Publication of ES8502109A1 publication Critical patent/ES8502109A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

ES532044A 1981-08-13 1984-04-30 Un procedimiento de preparacion de derivados de bencimidazol. Expired ES8502109A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8104811		1981-08-13

Publications (2)

Publication Number	Publication Date
ES532044A0 true ES532044A0 (es)	1984-12-16
ES8502109A1 ES8502109A1 (es)	1984-12-16

Family

ID=20344360

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES514947A Granted ES514947A0 (es)	1981-08-13	1982-08-12	"un procedimiento de preparacion de derivados de bencimidazol".
ES523344A Granted ES523344A0 (es)	1981-08-13	1983-06-16	Un procedimiento de preparacion de derivados de bencimidazol (divisional de la patente de invencion num. 514.947, presentada el 12 de agosto 1982)
ES532044A Expired ES8502109A1 (es)	1981-08-13	1984-04-30	Un procedimiento de preparacion de derivados de bencimidazol.

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
ES514947A Granted ES514947A0 (es)	1981-08-13	1982-08-12	"un procedimiento de preparacion de derivados de bencimidazol".
ES523344A Granted ES523344A0 (es)	1981-08-13	1983-06-16	Un procedimiento de preparacion de derivados de bencimidazol (divisional de la patente de invencion num. 514.947, presentada el 12 de agosto 1982)

Country Status (27)

Country	Link
US (1)	US4746667A (es)
EP (1)	EP0074341B1 (es)
JP (1)	JPS5839622A (es)
KR (1)	KR880001714B1 (es)
AT (1)	ATE18765T1 (es)
AU (1)	AU556736B2 (es)
CA (1)	CA1226223A (es)
CS (1)	CS249124B2 (es)
CY (1)	CY1450A (es)
DD (1)	DD202876A5 (es)
DE (1)	DE3270116D1 (es)
DK (1)	DK362482A (es)
ES (3)	ES514947A0 (es)
FI (1)	FI822813L (es)
GR (1)	GR76267B (es)
HK (1)	HK2189A (es)
HU (1)	HU190408B (es)
IE (1)	IE54215B1 (es)
IL (1)	IL66340A (es)
IS (1)	IS1360B6 (es)
MY (1)	MY8700139A (es)
NO (1)	NO822686L (es)
NZ (1)	NZ201538A (es)
OA (1)	OA07182A (es)
PH (1)	PH18635A (es)
PT (1)	PT75420B (es)
ZA (1)	ZA825106B (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4472409A (en) *	1981-11-05	1984-09-18	Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung	2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
DE3216843C2 (de) *	1982-05-05	1986-10-23	Ludwig Heumann & Co GmbH, 8500 Nürnberg	3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) *	1983-02-11	1983-02-11	Haessle Ab	Novel pharmacologically active compounds
IL71664A (en) *	1983-05-03	1987-11-30	Byk Gulden Lomberg Chem Fab	Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same
CA1259070A (en) *	1983-07-01	1989-09-05	Upjohn Company (The)	Substituted 2-¬monoannelated(3,4-,4,5-, and 5,6-)- pyridylalkylenesulfinyl\|-benzimidazoles
US4575554A (en) *	1983-12-05	1986-03-11	The Upjohn Company	Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
IL75400A (en) *	1984-06-16	1988-10-31	Byk Gulden Lomberg Chem Fab	Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8404065D0 (sv) *	1984-08-10	1984-08-10	Haessle Ab	Novel biologically active compounds
JPS6150978A (ja) *	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
JPS6150979A (ja) *	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
AU568441B2 (en) *	1984-09-24	1987-12-24	Upjohn Company, The	2-(pyridylalkenesulfinyl) benzimidazole derivatives
JO1406B1 (en) *	1984-11-02	1986-11-30	سميث كلاين اند فرينش لابوراتوريز ليمتد	Chemical compounds
GB8526154D0 (en) *	1985-02-06	1985-11-27	Kotobuki Seiyaku Co Ltd	2-substituted cyclo-heptoimidazoles
US4738975A (en) *	1985-07-02	1988-04-19	Takeda Chemical Industries, Ltd.	Pyridine derivatives, and use as anti-ulcer agents
AR243167A1 (es) *	1985-08-24	1993-07-30	Hoechst Ag	Procedimiento para la preparacion de toluidinas sustituidas.
EP0786461A1 (en) *	1986-11-13	1997-07-30	Eisai Co., Ltd.	Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same
FI90544C (fi) *	1986-11-13	1994-02-25	Eisai Co Ltd	Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
JP2718945B2 (ja) *	1987-06-17	1998-02-25	エーザイ株式会社	ピリジン誘導体及びそれを含有する潰瘍治療剤
FI96860C (fi) *	1987-06-17	1996-09-10	Eisai Co Ltd	Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
US5223515A (en) *	1988-08-18	1993-06-29	Takeda Chemical Industries, Ltd.	Injectable solution containing a pyridyl methylsulfinylbenzimidazole
AT394368B (de) *	1990-08-07	1992-03-25	Byk Gulden Lomberg Chem Fab	Verfahren zur herstellung von 3,4-dialkoxypyridinen
CA2136993A1 (en) *	1992-06-01	1993-12-09	Takeshi Kawakita	Pyridine compound and pharmaceutical use thereof
US5504082A (en) *	1992-06-01	1996-04-02	Yoshitomi Pharmaceutical Industries, Ltd.	Pyridine compound and pharmaceutical compostions
US5387600A (en) *	1992-07-30	1995-02-07	Fuji Photo Film Co., Ltd.	Treating arteriosclerosis using benzimidazole compositions
EP0729957A4 (en) *	1993-10-29	1996-12-27	Yoshitomi Pharmaceutical	PYRIDINE COMPOUND AND ITS USE AS A REMEDY
JP3559045B2 (ja)	1994-06-10	2004-08-25	ナウチノ−イススレドバテルスキインスティテュトファルマコロギイロスシイスコイアカデミイメディツィンスキフナウク	薬理学的活性を有する２−メルカプトベンズイミダゾール誘導体
US7230014B1 (en)	1997-10-14	2007-06-12	Eisai Co., Ltd.	Pharmaceutical formulation comprising glycine as a stabilizer
US6245913B1 (en)	1999-06-30	2001-06-12	Wockhardt Europe Limited	Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
DE10140492A1 (de)	2001-08-17	2003-08-14	Gruenenthal Gmbh	Hydrate von gegebenenfalls substituierten 2-(2-Pyridinyl)methylthio-1H-benzimidazolen und Verfahren zu ihrer Herstellung
JP5173191B2 (ja)	2004-09-13	2013-03-27	武田薬品工業株式会社	酸化化合物の製造方法及び製造装置
SI2003130T1 (sl)	2006-03-10	2012-02-29	Arigen Pharmaceuticals Inc	Nov piridinski derivat, ki ima aktivnost proti Helicobacter pylori
WO2008057802A2 (en)	2006-10-27	2008-05-15	The Curators Of The University Of Missouri	Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
AU2007335663B2 (en)	2006-12-18	2011-12-15	Link Genomics, Inc.	Helicobacter pylori eradicating agent having inhibitory activity on gastric acid secretion
CN101980700A (zh)	2008-02-20	2011-02-23	密苏里大学董事会	包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法
RU2484089C1 (ru) *	2009-04-09	2013-06-10	Ариджен Фармасьютикалз, Инк.	Тиопроизводное пиридина и фармацевтическая композиция, которая его содержит и имеет способность действовать против helicobacter pylori
US8722026B2 (en) *	2010-01-06	2014-05-13	Elc Management, Llc	Skin lightening compositions
US8992897B2 (en) *	2010-01-06	2015-03-31	Elc Management Llc	Skin lightening compositions
AU2013267022B2 (en) *	2010-01-06	2016-04-21	Elc Management Llc	Skin lightening compositions
IL307576B1 (en) *	2016-09-14	2025-02-01	Yufeng Jane Tseng	History of new modified benzimidazoles as D-amino acid oxidase (DAAO) inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7112208A (es) *	1971-09-04	1973-03-06
SE418966B (sv) *	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) *	1974-05-16	1981-01-26	Haessle Ab	Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (es) *	1977-09-19	1981-07-25	Hoffmann La Roche
SE7804231L (sv) *	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
US4359465A (en) *	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
CH644116A5 (de) *	1980-08-21	1984-07-13	Hoffmann La Roche	Imidazolderivate.
US4472409A (en) *	1981-11-05	1984-09-18	Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung	2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects

1982
- 1982-07-16 IL IL66340A patent/IL66340A/xx not_active IP Right Cessation
- 1982-07-16 ZA ZA825106A patent/ZA825106B/xx unknown
- 1982-08-05 NO NO822686A patent/NO822686L/no unknown
- 1982-08-09 NZ NZ201538A patent/NZ201538A/en unknown
- 1982-08-09 AU AU86978/82A patent/AU556736B2/en not_active Ceased
- 1982-08-10 OA OA57774A patent/OA07182A/xx unknown
- 1982-08-10 PH PH27697A patent/PH18635A/en unknown
- 1982-08-11 AT AT82850166T patent/ATE18765T1/de not_active IP Right Cessation
- 1982-08-11 DE DE8282850166T patent/DE3270116D1/de not_active Expired
- 1982-08-11 KR KR8203613A patent/KR880001714B1/ko active Pre-grant Review Request
- 1982-08-11 EP EP82850166A patent/EP0074341B1/en not_active Expired
- 1982-08-11 DD DD82242428A patent/DD202876A5/de not_active IP Right Cessation
- 1982-08-11 IE IE1940/82A patent/IE54215B1/en not_active IP Right Cessation
- 1982-08-12 PT PT75420A patent/PT75420B/pt not_active IP Right Cessation
- 1982-08-12 JP JP57139276A patent/JPS5839622A/ja active Granted
- 1982-08-12 CA CA000409351A patent/CA1226223A/en not_active Expired
- 1982-08-12 FI FI822813A patent/FI822813L/fi not_active Application Discontinuation
- 1982-08-12 HU HU822603A patent/HU190408B/hu not_active IP Right Cessation
- 1982-08-12 ES ES514947A patent/ES514947A0/es active Granted
- 1982-08-12 DK DK362482A patent/DK362482A/da not_active Application Discontinuation
- 1982-08-13 GR GR69047A patent/GR76267B/el unknown
- 1982-08-13 IS IS2749A patent/IS1360B6/is unknown
- 1982-08-13 CS CS826004A patent/CS249124B2/cs unknown
1983
- 1983-06-16 ES ES523344A patent/ES523344A0/es active Granted
1984
- 1984-04-30 ES ES532044A patent/ES8502109A1/es not_active Expired
1986
- 1986-12-10 US US06/939,274 patent/US4746667A/en not_active Expired - Fee Related
1987
- 1987-12-30 MY MY139/87A patent/MY8700139A/xx unknown
1989
- 1989-01-12 HK HK21/89A patent/HK2189A/xx not_active IP Right Cessation
- 1989-03-10 CY CY1450A patent/CY1450A/xx unknown

Also Published As

Publication number	Publication date
CA1226223A (en)	1987-09-01
EP0074341A1 (en)	1983-03-16
JPH0313203B2 (es)	1991-02-22
OA07182A (fr)	1984-04-30
PH18635A (en)	1985-08-23
IL66340A (en)	1986-08-31
PT75420B (en)	1986-12-09
HK2189A (en)	1989-01-20
CY1450A (en)	1989-03-10
ZA825106B (en)	1983-04-27
AU556736B2 (en)	1986-11-20
GR76267B (es)	1984-08-04
IS2749A7 (is)	1983-02-14
DE3270116D1 (en)	1986-04-30
DD202876A5 (de)	1983-10-05
NZ201538A (en)	1985-12-13
KR880001714B1 (ko)	1988-09-08
CS249124B2 (en)	1987-03-12
IE821940L (en)	1983-02-13
US4746667A (en)	1988-05-24
ES8500265A1 (es)	1984-10-01
KR840001156A (ko)	1984-03-28
IS1360B6 (is)	1989-05-25
PT75420A (en)	1982-09-01
AU8697882A (en)	1983-02-17
ES8502109A1 (es)	1984-12-16
IL66340A0 (en)	1982-11-30
MY8700139A (en)	1987-12-31
HU190408B (en)	1986-09-29
ES8401482A1 (es)	1983-12-16
DK362482A (da)	1983-02-14
NO822686L (no)	1983-02-14
IE54215B1 (en)	1989-07-19
ES523344A0 (es)	1984-10-01
EP0074341B1 (en)	1986-03-26
JPS5839622A (ja)	1983-03-08
FI822813L (fi)	1983-02-14
ATE18765T1 (de)	1986-04-15
FI822813A0 (fi)	1982-08-12
ES514947A0 (es)	1983-12-16

Publication	Publication Date	Title
ES532044A0 (es)	1984-12-16	Un procedimiento de preparacion de derivados de bencimidazol.
IL57577A (en)	1982-03-31	1,2-dihydroquinolin-2-one derivatives,processes for their preparation and pharmaceutical compositions containing the same
ES2001341A6 (es)	1988-05-16	Un procedimiento de producir un derivado de acido guanidinometilbenzoico.
IE812683L (en)	1982-05-28	Thieno-pyridine derivatives
ES8201979A1 (es)	1982-01-16	Procedimiento para la obtencion de derivados de bifeni- lil-azoliletano
JPS5432468A (en)	1979-03-09	Pyrrole derivatives
AU567498B2 (en)	1987-11-26	5-phenyl-1h-2,3-dihydro-1,4-benzodiazepine derivatives.
AU530949B2 (en)	1983-08-04	(1,2)-fused-7-phenyl-1,4-benzodiazepine
JPS5473797A (en)	1979-06-13	Pyride 3.2.1-jk carbazole derivative
JPS5246083A (en)	1977-04-12	Preparation of 3-amino-4-hyaroxycarbostyrils
JPS5246085A (en)	1977-04-12	Preparation of 3-amino-4-hydroxycarbostyrils
IE832769L (en)	1984-05-26	Acridanone derivative.
JPS5246084A (en)	1977-04-12	Preparation of 4-hydroxycarbostyril derivatives
JPS53119825A (en)	1978-10-19	1,3-dithioallophanate derivatives, their preparation, insecticides, acaricides, and bactericides for agricultural and horticultural uses
JPS5384991A (en)	1978-07-26	Novel nitrogen-containing heterocyclic compound and its preparation
JPS53119857A (en)	1978-10-19	Hydroxyindaneacetic acid derivatives and their preparation
JPS5418850A (en)	1979-02-13	Coloring of high polymeric organic materials

Legal Events

Date	Code	Title	Description
2001-01-01	FD1A	Patent lapsed	Effective date: 20001002