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ES517444A0 - Procedimiento para obtener medicamentos altamente solubles por atomizacion en presencia de un estabilizante y un agente inhibidor de formacion de cristales. - Google Patents

Procedimiento para obtener medicamentos altamente solubles por atomizacion en presencia de un estabilizante y un agente inhibidor de formacion de cristales.

Info

Publication number
ES517444A0
ES517444A0 ES517444A ES517444A ES517444A0 ES 517444 A0 ES517444 A0 ES 517444A0 ES 517444 A ES517444 A ES 517444A ES 517444 A ES517444 A ES 517444A ES 517444 A0 ES517444 A0 ES 517444A0
Authority
ES
Spain
Prior art keywords
atomization
stabilizer
procedure
crystal formation
inhibiting agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES517444A
Other languages
English (en)
Other versions
ES8505249A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Corp PLC
Original Assignee
Elan Corp PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corp PLC filed Critical Elan Corp PLC
Publication of ES8505249A1 publication Critical patent/ES8505249A1/es
Publication of ES517444A0 publication Critical patent/ES517444A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
ES517444A 1982-04-19 1982-11-17 Procedimiento para obtener medicamentos altamente solubles por atomizacion en presencia de un estabilizante y un agente inhibidor de formacion de cristales. Granted ES517444A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8206646A FR2525108B1 (fr) 1982-04-19 1982-04-19 Medicaments a haut degre de solubilite et procede pour leur obtention

Publications (2)

Publication Number Publication Date
ES8505249A1 ES8505249A1 (es) 1985-05-16
ES517444A0 true ES517444A0 (es) 1985-05-16

Family

ID=9273120

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517444A Granted ES517444A0 (es) 1982-04-19 1982-11-17 Procedimiento para obtener medicamentos altamente solubles por atomizacion en presencia de un estabilizante y un agente inhibidor de formacion de cristales.

Country Status (18)

Country Link
US (2) US4610875A (es)
JP (1) JPS58183615A (es)
AR (1) AR230183A1 (es)
AT (1) AT389813B (es)
AU (1) AU555579B2 (es)
BE (1) BE894942A (es)
CA (1) CA1225029A (es)
CH (1) CH655003A5 (es)
DE (1) DE3241097A1 (es)
ES (1) ES517444A0 (es)
FR (1) FR2525108B1 (es)
GB (1) GB2119784B (es)
IE (1) IE54084B1 (es)
IT (1) IT1153099B (es)
LU (1) LU84468A1 (es)
NL (1) NL8204461A (es)
PT (1) PT75867B (es)
SE (1) SE8206697L (es)

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JPH0648937A (ja) * 1992-04-07 1994-02-22 Seitai Kagaku Kenkyusho:Kk 経口投与に適する薬剤およびその製造方法
US5512300A (en) * 1992-09-15 1996-04-30 Warner-Lambert Company Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms
FR2722984B1 (fr) * 1994-07-26 1996-10-18 Effik Lab Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
BE1009856A5 (fr) * 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
US5686133A (en) * 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals
WO1997034601A1 (fr) * 1996-03-18 1997-09-25 Eisai Co., Ltd. Compositions medicamenteuses a solubilite amelioree
US6066339A (en) * 1997-10-17 2000-05-23 Elan Corporation, Plc Oral morphine multiparticulate formulation
US6086915A (en) * 1998-04-01 2000-07-11 Bioresponse L.L.C. Compositions and methods of adjusting steroid hormone metabolism through phytochemicals
AU763309B2 (en) * 1998-07-20 2003-07-17 Smithkline Beecham Corporation Bioenhanced formulations comprising eprosartan in oral solid dosage form
EP1120120A4 (en) * 1998-10-05 2009-04-29 Eisai R&D Man Co Ltd TABLETS DISSOLVING DIRECTLY IN MOUTH
EP1175205B1 (en) * 1999-11-12 2006-06-14 Abbott Laboratories Solid dispersion comprising ritonavir, fenofibrate or griseofulvin
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
AU784572B2 (en) * 1999-12-08 2006-05-04 Pharmacia Corporation Solid-state form of celecoxib having enhanced bioavailability
DZ3227A1 (fr) 1999-12-23 2001-07-05 Pfizer Prod Inc Compositions pharmaceutiques fournissant des concentrations de medicaments ameliorees
IL134701A0 (en) * 2000-02-23 2001-04-30 J P M E D Ltd Homogeneous solid matrix containing vegetable proteins
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
EP1297836A4 (en) 2000-06-16 2007-06-13 Mitsubishi Pharma Corp COMPOSITIONS FOR REGULATING THE RANGE AND / OR SPEED OF PH RELEASE
DK1334720T3 (da) * 2000-10-24 2009-01-19 Ajinomoto Kk Nateglinid-indeholdende fremstillinger
US20030170309A1 (en) * 2001-06-22 2003-09-11 Babcock Walter C. Pharmaceutical compositions containing polymer and drug assemblies
NZ529490A (en) * 2001-06-22 2005-08-26 Pfizer Prod Inc Pharmaceutical compositions of adsorbates of amorphous drug
EP1269994A3 (en) * 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmaceutical compositions comprising drug and concentration-enhancing polymers
SI21223A (sl) * 2002-06-19 2003-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom
US20040132771A1 (en) * 2002-12-20 2004-07-08 Pfizer Inc Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
US20050152932A1 (en) * 2003-06-12 2005-07-14 Valery Normand Non-crystalline perfume or flavor delivery system
US20050048112A1 (en) 2003-08-28 2005-03-03 Jorg Breitenbach Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US20080146615A1 (en) * 2004-12-20 2008-06-19 Dr. Reddy's Laboratories Limited Pharmaceutical Compositions Comprising Amorphous Benzimidazole Compounds
CA2603783C (en) * 2005-04-11 2014-11-18 Abbott Laboratories Pharmaceutical compositions having improved dissolution profiles for poorly soluble drugs
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
WO2007086039A1 (en) * 2006-01-27 2007-08-02 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin A method of producing porous microparticles
PT103743B (pt) * 2007-05-16 2013-01-15 Hovione Farmaciencia S A Processo para preparar derivados de 21-disódio fosfato de pregnanos.
CA2742356A1 (en) * 2008-11-04 2010-05-14 Cipla Limited Tiotropium bromide having a low degree of crystallinity
RU2013134339A (ru) 2010-12-23 2015-01-27 Эбботт Гмбх Унд Ко. Кг Твердые составы с замедленным действием на основе твердой дисперсии
CA2837266A1 (en) 2011-05-27 2012-12-06 Hetero Research Foundation Amorphous ritonavir co-precipitated

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
JPS5163925A (ja) * 1974-11-30 1976-06-02 Kyowa Hakko Kogyo Kk Muteikeikuroramufuenikooruno seizoho
US4127647A (en) * 1975-04-08 1978-11-28 Meiji Seika Kaisha, Ltd. Process for preparation of stable amorphous macrolide antibiotic solids
JPS51118816A (en) * 1975-04-08 1976-10-19 Meiji Seika Kaisha Ltd A process for stabilizing non-crystalloidal solid
DE2634004B2 (de) * 1976-07-29 1978-08-10 Bernhard Dr. 8000 Muenchen Lippold Verfahren zur Beschleunigung der Auflösung und Verbesserung der Löslichkeit von schlechtlöslichen zur peroralen Verabreichung bestimmten Arzneistoffen
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
US4128632A (en) * 1978-02-13 1978-12-05 Merck & Co., Inc. Solubilization of Rafoxanide
US4344934A (en) * 1978-11-20 1982-08-17 American Home Products Corporation Therapeutic compositions with enhanced bioavailability
JPS55139319A (en) * 1979-04-13 1980-10-31 Furointo Sangyo Kk Activation of drug soluble in alkali and acid
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
JPS587609B2 (ja) * 1979-06-17 1983-02-10 フロイント産業株式会社 粉体薬剤のコ−テング法
JPS6024768B2 (ja) * 1979-06-16 1985-06-14 フロイント産業株式会社 活性化薬剤の製法
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS5948810B2 (ja) * 1980-03-22 1984-11-29 山之内製薬株式会社 ニカルジピン持続性製剤用組成物
JPS5646837A (en) * 1979-09-27 1981-04-28 Kowa Yakuhin Kogyo Kk Preparation of ibuprofen clathrate compound
JPS5655370A (en) * 1979-10-13 1981-05-15 Kyorin Pharmaceut Co Ltd Amorphous nicomol
US4327080A (en) * 1981-07-13 1982-04-27 E. R. Squibb & Sons, Inc. Novel Bendroflumethiazide formulations and method
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
DE3318649A1 (de) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen Zweiphasenformulierung

Also Published As

Publication number Publication date
BE894942A (fr) 1983-05-09
US4769236A (en) 1988-09-06
JPS58183615A (ja) 1983-10-26
AU555579B2 (en) 1986-10-02
IE54084B1 (en) 1989-06-07
ES8505249A1 (es) 1985-05-16
US4610875A (en) 1986-09-09
LU84468A1 (fr) 1983-06-13
PT75867A (fr) 1982-12-01
CH655003A5 (fr) 1986-03-27
SE8206697D0 (sv) 1982-11-24
AU9043182A (en) 1983-10-27
ATA427282A (de) 1989-07-15
FR2525108A1 (fr) 1983-10-21
JPH0341444B2 (es) 1991-06-24
AR230183A1 (es) 1984-03-01
IE822610L (en) 1983-10-19
IT8224368A1 (it) 1984-05-23
NL8204461A (nl) 1983-11-16
DE3241097C2 (es) 1989-04-13
IT8224368A0 (it) 1982-11-23
SE8206697L (sv) 1983-10-20
AT389813B (de) 1990-02-12
FR2525108B1 (fr) 1989-05-12
IT1153099B (it) 1987-01-14
PT75867B (fr) 1986-01-21
GB2119784A (en) 1983-11-23
CA1225029A (en) 1987-08-04
GB2119784B (en) 1986-04-03
DE3241097A1 (de) 1983-10-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20011110